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Abstract 024 | Targeting fibro-adipogenic progenitors to treat Duchenne muscular dystrophy Luca Sali 1, Baptiste Periou 2, Andreea Cojocaru 1, Estelle Giry 1, Gianmarco Severa 1, Lorenzo Giordani 3, Valentina Taglietti 1, Edoardo Malfatti 2 | 1Université Paris-Est Créteil, INSERM, U955 IMRB, Créteil, France; 2Assistance Publique-Hôpitaux de Paris, Centre de Référence de Pathologie Neuromusculaire Nord-Est-Ile-de-France, Filnemus, Hôpital Henri Mondor, Créteil, France; European Reference Center for Neuromuscular Disorders, EURO-NMD, France; 3Sorbonne Université, INSERM UMRS 974, Association Institut de Myologie, Centre de Recherche en Myologie, 75013 Paris, France.
208Downloads: 120 -
2017Spring PaduaMuscleDays, roots and byproducts
1492Downloads: 881HTML: 352 -
Chemotherapy-induced muscle wasting: association with NF-κB and cancer cachexia
3952Downloads: 1910HTML: 210 -
Stem cells and tissue niche: two faces of the same coin of muscle regeneration
2465Downloads: 1185HTML: 749 -
Research into the physiology of myosins - a personal odyssey
1393Downloads: 664HTML: 12 -
Abstract 029 | Adulthood transition age in dystrophinopathies: a management model for integrated care delivery in Tuscany region Giulia Ricci 1, Francesca Torri 1, Sara Loprieno 1, Mariaconcetta Rende 1, Aruzhan Nugumanova 1, Michele Sacchini 2, Chiara Ticci 2, Guja Astrea 3, Bianca Buchignani 3, Elena Procopio 2, Roberta Battini 3, Gabriele Siciliano 1 | 1Department of Clinical and Experimental Medicine, University of Pisa, Italy; 2Metabolic and Muscular Diseases Unit, Meyer Children's Hospital IRCCS, Italy; 3Molecular Medicine for Neurodegenerative and Neuromuscular Diseases Unit, IRCCS Stella Maris Foundation, Calambrone Pisa, Italy.
217Downloads: 127 -
23 | Preclinical evaluation of 3s-HMGB1 as a therapeutic strategy for Duchenne muscular dystrophy Federica Esposito1, E. Sbolli1, S. Curtarello1, E. Ruggieri1|2, M. Patrone1|2, M. Rodrigues3, V. Taglietti3, F. Relaix3, E. Vénéreau1|2 | 1Unit, Division of Genetics and Cellular Biology, IRCCS Ospedale San Raffaele, Milan, Italy; 2University Vita-Salute San Raffaele, Milan, Italy; 3Univ Paris-Est Créteil, INSERM, U955 IMRB, Créteil, France.
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26 | Validation of a new multi-target antioxidant treatment for the therapy of Duchenne muscular dystrophy F. Fontana1|2, F. Carozzi1, G. Piccoli3, L. Nogara3, G. Romagnoli2, E. Petricci2, B. Blaauw3, M. Canton3, Libero Vitiello1, F. Galvagni2 | 1Dept. of Biology, Univ. of Padova, Italy; 2Dept. of Biotechnology, Chemistry and Pharmacy, Univ. of Siena, Italy; 3Dept. of Biomedical Sciences, Univ. of Padova, Italy.
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Do neurogenic and cancer-induced muscle atrophy follow common or divergent paths?
1300Downloads: 803HTML: 48 -
15 | GDF5 therapeutic potential for Duchenne muscular dystrophy C. Gentil, A. Bourguiba, A. Vergnol, B. Cadot, Z. Guesmia, L. Saillard, P. Meunier, S. Falcone, L. Giordani, France Pietri-Rouxel | Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
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41 | SRT2104 improves muscle and cognitive outcomes and has the potential to enhance μDys gene therapy in Duchenne muscular dystrophy Laura Lociuro1, A. Arcari2, O. Gjana1, G. Scolari1, S.R. Casati1|2, S. Zecchini2, M. Giovarelli2, C. Perrotta2, C. De Palma1 | 1Department of Medical Biotechnology and Translational Medicine (BioMeTra), Università degli Studi di Milano, Segrate (MI), Italy; 2Department of Biomedical and Clinical Sciences "Luigi Sacco" (DIBIC), Università degli Studi di Milano, Italy.
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Abstract 022 | Lecture: new insights leading to improved designs of micro-dystrophins for use in adeno-associated viruses vectors David Hammers, Cora Hart, Matthew Lee, H. Lee Sweeney, and UF Animal Assessment Core | University of Florida Myology Institute, Gainesville, Florida, USA.
213Downloads: 118 -
29 | RNA-based combinatorial multi-target therapy for the treatment of Duchenne muscular dystrophy Mathieu Horeau, C. Pezzini, M. Sandri | Department of Biomedical Sciences, University of Padova, Italy.
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25 | Target adipogenic progenitors to cure Duchenne muscular dystrophy Luca Sali1, B. Periou2, A. Cojocaru1, E. Giry1, G. Severa2, L. Giordani3, V. Taglietti1, E. Malfatti1|2 | 1Univ. Paris-Est Créteil, INSERM, U955 IMRB, Créteil, France; 2Assistance Publique-Hôpitaux de Paris, Centre de Référence de Pathologie Neuromusculaire Nord-Est-Ile-de-France, Filnemus, Hôpital Henri Mondor, Créteil, France; European Reference Center for Neuromuscular Disorders, EURO-NMD, France; 3Sorbonne Université, INSERM UMRS 974, Association Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
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16 | Immunoproteasome inhibition positively impacts the gut-muscle axis in Duchenne muscular dystrophy Debora Mostosi1, A. Farini2, F. Strati3, M. Molinaro2, S. Saccone2, C. Amoroso3, B. Cassani4, E. Leonetti1, F. Caprioli5, F. Facciotti3, Y. Torrente1|2 | 1Stem Cell Laboratory, Dino Ferrari Center, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 2Neurology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy; 4Department of Medical Biotechnologies and Translational Medicine, University of Milan, Italy; 5Department of Pathophysiology and Transplantation, University of Milan, Unit of Gastroenterology and Endoscopy, Fondazione IRCCS Ca’ Granda, Ospedale Policlinico di Milano, Italy.
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FES in Europe and beyond: Current Translational Research
1888Downloads: 1089HTML: 419 -
Assessing muscle architecture with ultrasound: implications for spasticity
1925Downloads: 1197HTML: 20 -
08 | Combination therapy targeting HDAC8 and SIRT1 improves muscle integrity in a Duchenne muscular dystrophy zebrafish model Sabrina Carbone1, A. Brix1, L. Lociuro1, O. Gjana1, L. Belleri2, M. Schiavone3, A. Marozzi1, F. Del Bene2, C. De Palma1, A. Pezzotta1, A. Pistocchi1 | 1Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy; 2Sorbonne Université, INSERM U968, CNRS UMR 7210, Institut de la Vision, Paris, France; 3Department of Molecular and translational medicine, Università degli Studi di Brescia, Brescia, Italy.
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11 | Human immortalized myoblasts/induced pluripotent stem cell derived skeletal muscle model to investigate cystinosis myopathy Jianhao Zhang1, R. Mora De La Serna2, M. Smits2, V. Marini1, A. Wang1, M. Biglietto1, M. Campaner Socias1, L. Rinvenuto1, Z. Ge1, R. Gijsbers2|3, M. Sampaolesi1|4 | 1Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; 3Leuven Viral Vector Core, KU Leuven, Leuven, Belgium; 4Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Rome, Italy.
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22 | Subcutaneous injection of microencapsulated Sertoli cells is more efficacious than deflazacort treatment in mdx mice Sara Chiappalupi1|2, G. Gentili1|2, L. Salvadori2|3, I. Arato1, F. Mancuso1, M. Paiella1|2, F. Riuzzi1|2, R. Calafiore1, G. Luca1, G. Sorci1|2 | 1Department of Medicine and Surgery, University of Perugia, Italy; 2Interuniversity Institute of Myology (IIM), Perugia, Italy; 3Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy. | S. Chiappalupi and G. Sorci shared Senior authorship; S. Chiappalupi and G. Gentili contributed equally.
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14 | Extracellular matrix guides human neuromuscular organoid morphogenesis Beatrice Auletta1|2|3, P. Chiolerio1|2, G. Cecconi1|2, L. Sartore1|2, L. Rossi1|2, E. Maghin4, S. Angiolillo3|5, S. Calabrò1, O. Gagliano3|5, C. Laterza3|5, M. Cescon1, Y. Torrente6|7, C. Luni8, M. Piccoli4, N. Elvassore3|5, A. Urciuolo1|2 | 1Department of Molecular Medicine, University of Padova, Padova, Italy; 2Neuromuscular Engineering lab, Istituto di Ricerca Pediatrica, Città della Speranza, Padova, Italy; 3Department of Industrial Engineering, University of Padova, Padova, Italy; 4Tissue Engineering lab, Istituto di Ricerca Pediatrica, Città della Speranza, Padova, Italy; 5Veneto Institute of Molecular Medicine, Padova, Italy; 6Stem Cell Laboratory, Dino Ferrari Center, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 7Neurology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 8Department of Civil, Chemical, Environmental and Materials Engineering (DICAM), University of Bologna, Italy.
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Pax7 reporter mouse models: a pocket guide for satellite cell research
2088Downloads: 1072HTML: 62 -
Culture conditions influence satellite cell activation and survival of single myofibers
1812Downloads: 1414HTML: 139 -
21 | Transcriptional and metabolic analyses of cardiac mononucleated cells in dystrophic mdx mice upon treatment with a specific monoamino oxidase B inhibitor Francesca Fontana1|2, F.C. Venegas3|4, E. Baldisseri3|4, R. Sánchez-Rodríguez3|4, A. Reggio5, A. Palma6, M. Canton3|4, L. Vitiello1 | 1Department of Biology, University of Padova, Italy; 2Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Italy; 3Fondazione Istituto di Ricerca Pediatrica Città della Speranza, IRP, Italy; 4Department of Biomedical Sciences, University of Padova, Italy; 5Saint Camillus International University of Health Sciences, Italy; 6Department of Biology and Biotechnologies "Charles Darwin", Sapienza University of Rome, Italy.
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2019Spring PaduaMuscleDays: Translational Myology and Mobility Medicine
1511Downloads: 767HTML: 31 -
13 | Generation of human stem cell-derived cardiac in vitro models to investigate the role of epicardial activation in adverse cardiac remodeling Margalida Campaner Socias1, V. Marini1, L. Rinvenuto1, A. Wang1, J. Zhang1, S. Morri1, D. Stalkopf1, R. Oida1, B. Sampaio1, M. Sampaolesi1|2 | 1Laboratory of Translational Cardiomyology, Stem Cell and Developmental Biology Unit, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy.
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04 | CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance Lorenzo Marramiero1|2, S. Di Savino1|2, E. Kheir1|2, M. Libergoli1|2, S. Metti3, A. Zola1|2, J.B. Jensen4|5, J.Wang5, N. Jessen4|5|6, F. Florio1|2, F. Murganti1|2, M. Belicchi 7|8, C. Villa8, K. Vissing9, M. Verma10, L. Giordani11, P. Bonaldo3, Y. Torrente7|8, J. Farup4, S. Biressi1|2 | 1Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Povo, Italy; 2Dulbecco Telethon Institute at University of Trento, Povo, Italy; 3Department of Molecular Medicine, University of Padova, Italy; 4Department of Biomedicine, Aarhus University, Denmark; 5Steno Dia,5betes Center Aarhus, Denmark; 6Department of Clinical Pharmacology, Aarhus University Hospital, Denmark; 7Neurology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 8Stem Cell Laboratory, Dino Ferrari Center, Department of Pathophysiology and Transplantation, University of Milan, Italy; 9Department of Public Health, Aarhus University, Denmark; 10University of Texas Southwestern Medical Center, Dallas, USA; 11Centre de Recherche en Myologie, Sorbonne Universités,Paris, France.
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EJTM3 is also covering Mobility and Medicine at large, an update
1196Downloads: 619HTML: 59