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Muscle pathology in upper motor neuron paraplegia
2306Downloads: 7067 -
Abstract 066 | Longitudinal study in low and high functioning older healthy adults: preliminary data on plasma metabolomics and muscle DNA methylation Samantha S. Ali, Ashley C. Amontree | College of Pharmacy, College of Medicine, University of Florida, Gainesville, USA.
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07 | Role of GDF5 on macrophage polarization in the maintenance of muscle mass and function and during aging Maxime Gelin1, E. Hemery1, F. Truffault1, G. Juban2, C. Perrotta3, F. Pietri-Rouxel1, M. Traoré1, S. Falcone1 | 1Centre de Recherche en Myologie – U974 INSERM, Sorbonne Université, Institut de Myologie, Paris, France; 2Institut NeuroMyoGène, Physiopathologie et Génétique du Neurone et du Muscle Université Claude Bernard Lyon 1, CNRS U5261, Inserm U1315, University Lyon, Lyon, France; 3Department of Biomedical and Clinical Sciences Università degli Studi di Milano, Milan, Italy. | M. Traoré and S. Falcone contributed equally to this work and corresponding authors. s.falcone@institut-myologie.org; m.traore@institut-myologie.org.
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Abstract 056 | Role of prohibitin isoforms in mitochondrial function with aging and exercise Sabrina Champsi, David A. Hood | Muscle Health Research Centre, School of Kinesiology and Health science, York University, Toronto, Canada.
107Downloads: 47 -
28 | Impairment of skeletal muscle force and mitochondrial respiratory capacity precedes muscle mass loss in an aged murine model of diet-induced obesity Clara Sciorati1, R. De Lorenzo1|2, A. Avola1, M. Giovarelli3, C. De Palma3, E. Clementi3, C. Lanzani1, P. Rovere-Querini1|2 | 1IRCCS San Raffaele Hospital Scientific Institute, Milan, Italy; 2Vita-Salute San Raffaele University, Milan, Italy; 3Department of Biomedical and Clinical Science, University of Milan, Italy.
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02 | Entrainment of skeletal muscle circaldian clock by 2-hydroxybutyrate, a noval exerkine Taoyue Yang1|2, L. Matta1, A. Bartelt1|3, K. Dyar1 | 1Institute for Diabetes and Cancer, Helmholtz Munich, Germany; 2Faculty of Medicine, Ludwig-Maximilian-Universität München, Germany; 3Traslational Nutritional Medicine, Technical University of Munich, Germany.
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Comments on: Effect of physical activity on long COVID fatigue
740Downloads: 319HTML: 5 -
32 | Trifolium pratense extract mitigates skeletal muscle atrophy: a nutraceutical approach for the prevention of sarcopenia Tommaso Raiteri1, H. Meskine2, M. Paiella1, A. Trabalzini1, I. Varfaj4, L. Salvadori2, F. Riuzzi1, R. Sardella4, F. Orlandi3, N. Filigheddu2, G. Sorci1 | 1Department of Medicine and Surgery, University of Perugia, Italy; 2Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 3Department of Civil and Environmental Engineering, University of Perugia, Italy; 4Department of Pharmaceutical Sciences, University of Perugia, Italy.
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44 | Targeted delivery of mir-486 to skeletal muscle: efficacy, tropism, and integrin dependency of MYOAAV2A vs. AAV9 Chiara Ricciardi1, S. Perni1, V. Sorrentino1|2 | 1Department of Molecular and Developmental Medicine, University of Siena, Italy; 2Interdepartmental Program of Molecular Diagnosis and Pathogenetic Mechanisms of Rare Genetic Diseases, Azienda Ospedaliera Universitaria Senese, Italy.
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Oxy-inflammation in hyperbaric oxygen therapy applications
1434Downloads: 712HTML: 11 -
11 | Human immortalized myoblasts/induced pluripotent stem cell derived skeletal muscle model to investigate cystinosis myopathy Jianhao Zhang1, R. Mora De La Serna2, M. Smits2, V. Marini1, A. Wang1, M. Biglietto1, M. Campaner Socias1, L. Rinvenuto1, Z. Ge1, R. Gijsbers2|3, M. Sampaolesi1|4 | 1Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; 3Leuven Viral Vector Core, KU Leuven, Leuven, Belgium; 4Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Rome, Italy.
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46 | Investigating the impact of the tumor secretome on in vitro human skeletal and cardiac muscle models of cancer-induced cachexia Ashley Ju-Wei Wang1, L. Yedigaryan 1|2, M. Campaner Socias1, J. Zhang1, F. Palmieri3, L. Rinvenuto1, V. Marini1, R. Squecco3, M. Seelaender4, M. Sampaolesi1|5 | 1Laboratory of Translational Cardiomyology, Stem Cell Institute Leuven, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, Illkirch, France; 3Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence, Italy; 4Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo, São Paulo SP, Brazil; 5Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy. | Correspondence to A. Ju-Wei Wang and M. Sampaolesi, ashley.wang@kuleuven.be; maurilio.sampaolesi@kuleuven.be.
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Abstract 002 | Muscle and brain dysfunction associated with modern critical care. Mechanisms and interventions Lars Larsson 1|2 | 1Department of Clinical Sciences, SLU, Uppsala, Sweden; 2Muscle Biology Program, Viron Molecular Medicine Institute, Boston, MA, USA.
142Downloads: 42 -
42 | RAGE-ablated skeletal muscles resist cancer-induced atrophy through Akt-GSK-3β-PGC-1α pathway and fast-to-slow myofiber transition Giulia Gentili1|2, S. Chiappalupi1|2, L. Salvadori1|3, M. Paiella1|2, K. Mangar4, A.M. Schmidt4, M. Muscaritoli5, F. Riuzzi1|2, G. Sorci1|2 | 1Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 2Interuniversity Institute of Myology (IIM), Perugia, Italy; 3Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 4Department of Medicine, NYU Grossman School of Medicine, New York, USA; 5Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; Giulia Gentili and S. Chiappalupi contributed equally; F. Riuzzi and G. Sorci Shared Senior authorship.
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Abstract 022 | Lecture: new insights leading to improved designs of micro-dystrophins for use in adeno-associated viruses vectors David Hammers, Cora Hart, Matthew Lee, H. Lee Sweeney, and UF Animal Assessment Core | University of Florida Myology Institute, Gainesville, Florida, USA.
96Downloads: 37 -
Abstract 031 | Lecture: the wonderful machine Stefano Schiaffino | Veneto Institute of Molecular Medicine - VIMM, Padua, Italy Veneto Institute of Molecular Medicine - VIMM, Padua, Italy.
92Downloads: 32 -
Abstract 069 | Exercise oncology and biomarkers: how skeletal muscle interacts with inflammation and immunity Elena Barbieri 1, Giosuè Annibalini 1, Mauro De Santi 1, Giulia Baldelli 1, Veronica Gentilini 1, Francesco Lucertini 1, Valentina Natalucci 1, Marta Imperio 1, Seyedehmahboobeh Mosavi 1, Roberta Saltarelli 1, Fabio Ferrini 1, Matteo Bocconcelli 1, Davide Sisti 1, Simone Barocci 2, Vincenzo Catalano 1, Rita Emili 1 | 1Department of Biomolecular Sciences, University of Urbino, Italy; 2Ospedale Santa Maria della Misericordia, AST Pesaro Urbino, Italy; 3Department of Medicine and Surgery, Section of Hygiene and Public Health, University of Perugia, Perugia, Italy.
94Downloads: 48 -
Abstract 008 | Functional and structural specialization of human donor tendons Jan Fridén 1, Richard L. Lieber 2|3|4 | 1Swiss Paraplegic Center Nottwil, Switzerland; 2Northwestern University, Chicago USA; 3Shirley Ryan AbilityLab, Chicago USA; 4Hines VA Medical Center, Chicago USA.
117Downloads: 49 -
43 | Synergistic negative effects of advanced glycation end products and tumor-conditioned medium on C2C12 myotubes and the protective activity of Vaccinium macrocarpon T. Raiteri2, Hajar Meskine1, L. Salvadori1, M. Paiella2, F. Prodam3, F. Riuzzi2, N. Filigheddu1 | 1Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 2Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 3Department of Health Science, University of Piemonte Orientale, Novara, Italy.
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Abstract 030 | Expression of the ERG1A potassium channel affects nanoscale membrane characteristics of cultured skeletal muscle cells Amber L. Pond 1, Annie Yojaira Vargas Lizarazo 2, Judith K. Davie 1, Punit Kohli 2 | 1Department of Basic Medical Sciences, School of Medicine, Southern Illinois University; 2School of Chemical and Biomolecular Sciences, Southern Illinois University Carbondale, Illinois, USA.
96Downloads: 51 -
Abstract 060 | Muscle transcriptomics involved in mitochondrial ets activities are associated with cardiorespiratory fitness and physical performance in older adults in the study of muscle, mobility and aging (somma) Bumsoo Ahn 1|2, Tyler A. Mansfield 3, Peggy M. Cawthon 3|4, Paul M. Coen 5, Russell T. Hepple 6, Karyn A. Esser 7, Gregory J. Tranah 3|4, Nancy W. Glynn 8, Daniel S. Evans 3|4, Theresa Mau 3, Bret H. Goodpaster 5, Michael J. Jurczak 9, Anne B. Newman 8, Steven R. Cummings 3|4, Stephen B. Kritchevsky 1|2 | 1Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; 2Sticht Center for Healthy Aging and Alzheimer’s Prevention, Wake Forest School of Medicine; Winston-Salem, NC, USA; 3San Francisco Coordinating Center, California Pacific Medical Center Research Institute, Sutter health, San Francisco, California, USA; 4Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA; 5Translational Research Institute, AdventHealth, Orlando, Florida, USA; 6Department of Physical Therapy, University of Florida College of Medicine, Gainesville, Florida, USA; 7Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL; 8Department of Epidemiology, University of Pittsburgh, Pennsylvania, USA; 9Division of Endocrinology and Metabolism, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
102Downloads: 37 -
10 | Human myogenic progenitor and 3D bioprinting for volumetric muscle loss recovery in swine model Rebecca Deodati, F. De Paolis, E. Guarnaccia, B. Corci, S. Bernardini, M. Costantini, C. Fuoco, C. Gargioli | Dept. of Biology, University of Tor Vergata, Rome, Italy.
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04 | CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance Lorenzo Marramiero1|2, S. Di Savino1|2, E. Kheir1|2, M. Libergoli1|2, S. Metti3, A. Zola1|2, J.B. Jensen4|5, J.Wang5, N. Jessen4|5|6, F. Florio1|2, F. Murganti1|2, M. Belicchi 7|8, C. Villa8, K. Vissing9, M. Verma10, L. Giordani11, P. Bonaldo3, Y. Torrente7|8, J. Farup4, S. Biressi1|2 | 1Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Povo, Italy; 2Dulbecco Telethon Institute at University of Trento, Povo, Italy; 3Department of Molecular Medicine, University of Padova, Italy; 4Department of Biomedicine, Aarhus University, Denmark; 5Steno Dia,5betes Center Aarhus, Denmark; 6Department of Clinical Pharmacology, Aarhus University Hospital, Denmark; 7Neurology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 8Stem Cell Laboratory, Dino Ferrari Center, Department of Pathophysiology and Transplantation, University of Milan, Italy; 9Department of Public Health, Aarhus University, Denmark; 10University of Texas Southwestern Medical Center, Dallas, USA; 11Centre de Recherche en Myologie, Sorbonne Universités,Paris, France.
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22 | Subcutaneous injection of microencapsulated Sertoli cells is more efficacious than deflazacort treatment in mdx mice Sara Chiappalupi1|2, G. Gentili1|2, L. Salvadori2|3, I. Arato1, F. Mancuso1, M. Paiella1|2, F. Riuzzi1|2, R. Calafiore1, G. Luca1, G. Sorci1|2 | 1Department of Medicine and Surgery, University of Perugia, Italy; 2Interuniversity Institute of Myology (IIM), Perugia, Italy; 3Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy. | S. Chiappalupi and G. Sorci shared Senior authorship; S. Chiappalupi and G. Gentili contributed equally.
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Abstract 028 | Modelling satellite cell dysfunction to understand pathogenesis of neuromuscular disorders Massimo Ganassi | Genetic Therapy Accelerator Centre, Queen Square Institute of Neurology, University College London, London, UK.
104Downloads: 38