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065 | Phytochemical profile, oxidative response and antimicrobial activity of Scutellaria lateriflora extract against Staphylococcus aureus Dionysia Amanatidou1, Ioannis Tsamesidis1|2, Stylaini Axipolitou2, Nektaria Grammatika2, Antonella Pantaleo3, Eleana Kontonasaki2, Phaedra Eleftheriou1 | 1Department of Biomedical Sciences, International Hellenic University, Thessaloniki, Greece; 2Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece; 3Department of Biomedical Science, University of Sassari, Italy.
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155 | Mitochondrial dynamics and therapeutic insights in spinal muscular atrophy: effects of MFN2 boosting in motoneurons and human fibroblasts Francesco Paolo Zummo1, Serena Stanga1, Letizia Paladino2, Maria Beltran3, Francesco Fedeli4, Maria Rosa Soler3, Fabio Bucchieri5, Marina Boido1 | 1Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy; 2E-Campus University, Palermo, Italy; 3Neuronal Signaling Unit, Experimental Medicine Department, University of Lleida-IRBLleida, Lleida, Spain; 4University of Pavia, Italy; 5Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy.
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064 | Sustainable extraction and functional characterization of bioactive compounds from Spirulina platensis for nutraceutical and cosmetic applications Carmen Sica1, Chiara Copat1, Gea Oliveri Conti1, Sheima Inoubli2, Margherita Ferrante1 | 1Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Italy; 2Department of Chemical Engineering, Universidade de Vigo, Campus de Ourense, Spain.
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162 | Functional and health-promoting properties of EVOO from Sicilian olive cultivars: focus on oxidative stress and inflammation Mariateresa Cristani1, Ali Mert Yetisgin2, Giovanni Bartolomeo3, Nicola Cicero3|4, Rosaria Costa3, Nicola Micale1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2İnönü University, Faculty of Pharmacy, Kampüs, Battalgazi/Malatya, Türkiye; 3Department of Biomedical, Dental, Morphological and Functional Images Sciences BIOMORF, University of Messina, Messina, Italy; 4Science4Life srl, start-up of the University of Messina, Messina, Italy.
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124 | Immunomodulatory effects of extracellular vesicles from invertebrate species on human cells Kristian Riolo1, Francesco Di Pietro1, Sabrina Oliva1, Claudia Mosca1, Valeria Stefanizzi1, Giovanna Montana2, Annalisa Pinsino2, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy.
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025 | Protect colorectal cancer: in vitro chemopreventive effects of bronte pistachio extracts on colorectal cancer cells Graziella Serio1, Roberto Chiarelli1, Giuseppe Mannino2, Samuele Davì1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Life Sciences and Systems Biology, Innovation Centre, University of Turin, Italy.
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116 | Exosomes and miRNA content engagement in inflammatory processes let's take stock in the veterinary field Francesca Arfuso1, Jessica M. Abbate2, Claudia Giannetto1, Marilena Briglia3, Elisabetta Giudice1, Giovanni Lanteri2, Giuseppe Piccione1 | 1Department of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, Messina, Italy; 2Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, Polo Universitario Papardo, Messina, Italy; 3Department of Medicine and Surgery “Kore”, University of Enna, Italy.
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059 | Marine cyanobacterial biomasses as biocompatible soil-wetting and water-retention agents Angela Macrì1|2, Vincenzo Zammuto1|2, Alice Restifo Chiavetta1, Antonio Ficara1, Erminia Conti3, Diego Leone3, Patrizia Trifilò1, Maria Teresa Caccamo2|4, Salvatore Magazù2|4, Concetta Gugliandolo1|2 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2University of Messina, Research Centre for Extreme Environments and Extremophiles, Messina, Italy; 3Department of Biological, Geological and Environmental Sciences, University of Catania, Italy; 4Department of Mathematical and Computer Sciences, Physical and Earth Sciences, University of Messina, Italy.
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107 | Protective effects of hydroxytyrosol against dichlorodiphenilethylene-induced oxidative injury in liver cells Vincenzo Migliaccio1, Ilaria Di Gregorio1, Martina Coletta1, Giuliana Panico2, Assunta Lombardi2, Lillà Lionetti1 | 1Dept Chemistry and Biology “Adolfo Zambelli”, University of Salerno, Italy; 2Dept Biology, University Federico II, Napoli, Italy.
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143 | Anodal tDCS enhances decision precision during biological motion perception: a computational active inference perspective Antonio Cangelosi1, Umberto Quartetti1, Giulio Musotto2, Dimitri Ognibene3, Giuditta Gambino1, Giuseppe Giglia1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, Section of Human Physiology, University of Palermo, Italy; 2Bioengineering Unit, RiMED Foundation, Palermo, Italy; 3Department of Psychology, University of Milan-Bicocca, Milan, Italy.
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187 | Beyond marker genes: mitochondrial genomics as a high-resolution tool for Sporothrix schenckii molecular epidemiology Laura Taca1, Andrea Bonomo2, Gabriele Rigano3|4, Letterio Giuffrè1, Orazio Romeo1, Domenico Giosa1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Mathematics, University of Pavia, Italy; 3Department of Biology, University of Rome “Tor Vergata”, Rome, Italy; 4PhD programme in Space Science and Technology, Department of Physics, University of Trento, Italy.
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103 | Valorization of olive mill wastewaters for the recovery of polyphenols with reducing, radical scavenging and anti-inflammatory activities Francesco Longo1, Luisa Tesoriere1, Claudio Luparello1, Ignazio Restivo1, Federica Bellistrì1, Serena Indelicato1, David Bongiorno1, Rosi De Luca1, Giulia Abruscato1, Antonio Fabbrizio2, Salvatore Terrani3, Mirella Vazzana1, Vincenzo Arizza1, Manuela Mauro1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences DiSTA, University e Campus, Novedrate [CIO], Italy; 3The Wave Innovation Group, Verona, Italy.
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142 | Drug repositioning reveals novel therapeutic candidates for spinal muscular atrophy Marina Boido1, Daniela Maria Rasà1, Serena Stanga1, Ersilia Nicorvo1, Pamela Santonicola2, Nadia Mazzarella3, Antonella Camera2, Roberto Iacomino2, Ilenia Matino2, Silvia Chasseur1, Giuseppina Zampi2, Piera Smeriglio4, Elia Di Schiavi2, Alessandro Vercelli1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy; 2Institute of Biosciences and BioResources IBBR, National Research Council CNR, Naples, Italy; 3Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" IGB-ABT, National Research Council CNR, Naples, Italy; 4Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
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054 | Biostimulant-mediated mitigation of hypoxic stress and recovery in lettuce under flooding conditions Chiara Dellapiana1, Chiara Agliassa2, Francesco Caldo1, Moez Maghrebi1, Valeria Contartese2, Giuseppe Mannino1, Gianpiero Vigani1 | 1Department of Life Sciences and Systems Biology, University of Turin, Italy; 2Green Has Italia SpA, Canale [AT], Italy.
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100 | Tracking polystyrene nanoplastics by raman microscopy reveals intestinal and retinal toxicity Valentina Iezzi1, Roberta Maria Ferri1, Annamaria Iannetta2, Ludovica Sulcanese2, Tommaso Silvestrini2, Vanessa D’Altilia2, Giovanni Angelozzi2, Federico Perrella3, Carino Ferrante4, Giulia Fioravanti3, Monia Perugini2, Elisabetta Benedetti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Italy; 3Department of Physical and Chemical Sciences University of L’Aquila, Italy; 4CNR-SPIN, c/o department of Physical and Chemical Sciences University of L’Aquila, Italy.
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125 | Impact of 2D and 3D in vitro culture models on extracellular vesicles in human ovarian cancer Giulia Di Fazio1, Giuseppina Poppa1, Giuseppe Cammarata2, Sandra D’Ascenzo1, Vincenza Dolo1, Simona Taverna2, Ilaria Giusti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Institute of Translational Pharmacology IFT, National Research Council of Italy CNR, Palermo, Italy.
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043 | Hemocyte motility integrated into a multimarker ecophysiological approach for thermal stress assessment in native and invasive bivalve species Gayatri Udayan, Claudio Calabrese1, Daniele Arduini; Antonella Giacovelli1, Maria Elena Giordano1, Adriana Giangrande1|2, Maria Giulia Lionetto1|2 | 1Dept Biological and Environmental Sciences and Technologies DiSTeBA, University of Salento; 2NBFC, National Biodiversity Future Center, Palermo, Italy.
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160 | Short-term mild caloric restriction induces early adaptive metabolic and mitochondrial responses in the liver of healthy rats Martina Coletta1, Vincenzo Migliaccio1, Giuliana Panico2, Ilaria Di Gregorio1, Assunta Lombardi2, Lillà Lionetti1 | 1Dept Chemistry and Biology "A Zambelli", University of Salerno, Italy; 2Dept Biology, University of Naples Federico II, Naples, Italy.
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075 | Cytotoxic effects of grape seed oils on cancer cells Daniela Ganci1, Giulia Abruscato1, Roberto Chiarelli1, Manuela Mauro1|2, Vincenzo Arizza1|2, Mirella Vazzana1|2, Claudio Luparello1|2 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; 2NFBC, National Biodiversity Future Center, Palermo, Italy.
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072 | A standardized onion peel-derived bioactive ingredient attenuates palmitate-induced steatosis and oxidative stress in HepG2 cells Ilaria Di Gregorio1|2, Vincenzo Migliaccio2, Maria D’Elia1|3|4, Rita Celano1|3, Anna Lisa Piccinelli1|3, Luca Rastrelli1|3, Lillà Lionetti2|3 | 1Dept Pharmacy, University of Salerno, Salerno, Italy; 2Dept Chemistry and Biology “A Zambelli”, University of Salerno, Italy; 3National Biodiversity Future Center NBFC, Palermo, Italy; 4Dept Earth and Marine Sciences, University of Palermo, Italy.
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