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Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

Editors-in-Chief: Gian Luigi Mariottini - Antonella Marino Gammazza, Italy | eISSN 2284-0230 - pISSN 1826-8838

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  • Role of Cell-Cell bond for the viability and the function of vascular smooth muscle cells

    M. Mura, S. Garibaldi, C. Barisione, E. Fulcheri, G. Ghigliotti, I. Tracchi, C. Aloi, P. Fabbi, P. Altieri, P. Spallarossa, C. Brunelli
    30-01-2010
    https://doi.org/10.4081/jbr.2010.4438
    801
    Downloads: 544
  • 064 | Sustainable extraction and functional characterization of bioactive compounds from Spirulina platensis for nutraceutical and cosmetic applications Carmen Sica1, Chiara Copat1, Gea Oliveri Conti1, Sheima Inoubli2, Margherita Ferrante1 | 1Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Italy; 2Department of Chemical Engineering, Universidade de Vigo, Campus de Ourense, Spain.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15316
    81
  • 161 | Anle 138b inclusion complex with methyl-β-cylodextrin: a novel liquid formulation for administration in Parkinson disease Giuditta Colangelo1, Adriana Trapani2, Giuseppe Fracchiolla2, Rosa Angela Cardone3, Anna Patrizia De Nichilo2, Stefano Castellani4, Michele Maffia5, Massimo Conese1, Rosanna Mallamaci3 | 1Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 2Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, Bari, Italy; 3Department of Biosciences, Biotechnologies and Environment, University of Bari “Aldo Moro”, Bari, Italy; 4Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J, University of Bari “Aldo Moro”, Bari, Italy; 5Department of Biological and Environmental Science and Technologies DiSTeBA, University of Salento, Lecce, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15413
    106
  • 011 | Physicochemical and biological evaluation of IgG binding to self-assembling dendrimer nanomicelles Gabriele Cavalieri, Anna Laura La Monaca, Erik Laurini, Sabrina Pricl | Molecular Biology and Nanotechnology Laboratory - MolBNL@UniTS, Department of Engineering and Architecture - DEA, University of Trieste, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15263
    86
  • In vitro biocontrol of phytopathogenic fungi isolated from the rhizosphere of multiple crops by a native Trichoderma strain

    Alondra Santos Villegas, Nuria Jiménez-Juárez, Minerva Rosas Morales, Dalia Castillo-Hernández
    16-04-2024
    https://doi.org/10.4081/jbr.2024.11664
    1011
    Downloads: 806
  • 077 | Activation of the Keap1–Nrf2 axis underlies the antioxidant astrocytes protective effects of Boswellia sacra ethanolic extract: in vitro evidences supported by in silico analysis Graziella Serio1, Alessia Bono1, Roberto Chiarelli1, Marta Amato1, Mariangela Geraci1, Adriano Trapani1, Alessia Vermiglio1, Lorenza La Rosa1, Andrea Occhipinti2, Gabriella Schiera1, Antonino Lauria1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Abel Nutraceuticals SRL, Turin, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15329
    113
  • 02 | MICROPLASTICS ENDOCRINE-DISRUPTING CHEMICALS AND HUMAN HEALTH: METABOLIC AND REPRODUCTIVE RISKS IN A ONE HEALTH PERSPECTIVE Oliana Carnevali | Department of Life and Environmental Sciences, Università Politecnica delle Marche, Ancona, Italy

    Società Italiana di Biologia Sperimentale
    20-04-2026
    https://doi.org/10.4081/jbr.2026.15571
    179
    Downloads: 66
  • 024 | In vitro analysis of molecular chaperone involvement in the radiological response of triple-negative breast cancer models Giusi Alberti1, Giuseppe Vergilio1, Domiziana Picone1, Denise Amico1, Rosario Barone1, Francesca Rappa1, Marco Calvaruso3, Gaia Pucci3, Luigi Minafra3, Antonella Marino Gammazza2 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostic BIND, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; 3Institute of Bioimaging and Complex Biological Systems-National Reasearch Council IBSBC-CNR, Cefalù-Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15276
    78
  • Characterization of sponge-associated actinobacteria with potential to promote plant growth on tidal swamps

    Dwi Retnowati, Dedy Duryadi Solihin, Munif Ghulamahdi, Yulin Lestari
    26-09-2019
    https://doi.org/10.4081/jbr.2019.8191
    1082
    Downloads: 741
  • Airborne microplastics: a Trojan horse for respiratory dysfunction and multiorgan damage

    Domiziana Picone, Adelaide Carista, Giulia Maria Giorgia Lo Piano, Olga Maria Manna, Stefano Burgio, Fabio Bucchieri, Giuseppa D'Amico, Alessandro Pitruzzella, Alberto Fucarino
    22-10-2025
    https://doi.org/10.4081/jbr.2025.13945
    340
    Downloads: 342
  • 062 | Enriched bioplastics with natural compounds as innovative hemocompatible biomaterials targeting red blood cells Stefano Putaggio, Annamaria Russo, Giuseppe Tancredi Patanè, Claudia Gravagno, Antonella Calderaro, Davide Barreca, Silvana Ficarra, Ester Tellone | Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15314
    85
  • Fourier transform infrared conformational investigation of type I collagen aged by in vitro induced dehydration and non-enzymatic glycation treatments

    Maria Grazia Bridelli, Chiaramaria Stani, Roberta Bedotti
    16-10-2017
    https://doi.org/10.4081/jbr.2017.6254
    103116
    Downloads: 1098
  • MICROFLUIDIC SYNTHESIS OF PLA NANOPARTICLES: COMPARISON OF DIFFERENT SYSTEMS TO ACHIEVE HIGH SCALABILITY AND BATCH-TO-BATCH REPRODUCIBILITY Federica MONTELLA , Erwin Pavel LAMPARELLI, Giovanna DELLA PORTA | Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi (SA), Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14577
    241
  • 150 | New strategies to counteract dopaminergic degeneration: in vitro and in vivo neurotrophic properties of a tetrahydro-isoquinoline derivative as a novel mGlu2/3 agonist/positive allosteric modulator Miriana Scordino1, Giulia Urone1, Monica Frinchi1, Lucia Seidita1, Alessandra Montalbano2, Marilia Barreca2, Paola Barraja2, Maria Valeria Raimondi2, Roberta Bivacqua2, Fanny Malhaire3, Cyril Goudet3, Giuseppa Mudò1, Virginia Spanò2, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 3IGF, Université de Montpellier, CNRS, INSERM, France.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15402
    82
  • Magnolia officinalis: botanical characteristics, pharmacological properties and current evidence from preclinical studies

    Martina Martorana, Fabio Venturella
    30-03-2026
    https://doi.org/10.4081/jbr.2026.14131
    520
    Downloads: 219
  • 075 | Cytotoxic effects of grape seed oils on cancer cells Daniela Ganci1, Giulia Abruscato1, Roberto Chiarelli1, Manuela Mauro1|2, Vincenzo Arizza1|2, Mirella Vazzana1|2, Claudio Luparello1|2 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; 2NFBC, National Biodiversity Future Center, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15327
    87
  • Escherichia coli isolated from human polymicrobial bacteriuria are able to suppress in vitro interleukin production

    D. Saverino, A.M. Schito, A. Mannini, S. Penco, A.M. Bassi, G. Piatti
    30-01-2011
    https://doi.org/10.4081/jbr.2011.4658
    2291
    Downloads: 754
  • 071 | Decoding eryptosis: human red blood cells response to xenobiotic-induced stress Marilena Briglia1, Alice Foti1, Fabio Allia1, Rosalia Battaglia1, Giuseppe Piccione2, Alessandro Attanzio3, Caterina Faggio4, Roberta Malaguarnera1, Adriana Carol Eleonora Graziano1 | 1Department of Medicine and Surgery, University of Enna “Kore”, Enna, Italy; 2Department of Veterinary Sciences, University of Messina, Messina, Italy; 3Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 4Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15323
    95
  • 022 | Physiologic remodelling in 3D hepatocellular carcinoma models: temporal evolution from day 0 to day 9 Serena Munaò, Alessandra Armeli, Desirèe Bonfiglio, Giovanna Calabrese | Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences ChiBioFarAm, University of Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15274
    84
  • Antitumoral activity of curcumin: an adjuvant therapeutic strategy

    Giovanni Tomasello, Marco Giammanco, Margherita Mazzola, Provvidenza Damiani, William Ra’, Paola Giammanco, Francesca Rappa, Alessandro Pitruzzella, Dario Saguto, Benedetto Di Trapani, Giovanni Taverna, Mike Carini, Antonio Ciulla, Francesco Carini
    21-01-2021
    https://doi.org/10.4081/jbr.2020.8252
    848
    Downloads: 480
  • 103 | Valorization of olive mill wastewaters for the recovery of polyphenols with reducing, radical scavenging and anti-inflammatory activities Francesco Longo1, Luisa Tesoriere1, Claudio Luparello1, Ignazio Restivo1, Federica Bellistrì1, Serena Indelicato1, David Bongiorno1, Rosi De Luca1, Giulia Abruscato1, Antonio Fabbrizio2, Salvatore Terrani3, Mirella Vazzana1, Vincenzo Arizza1, Manuela Mauro1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences DiSTA, University e Campus, Novedrate [CIO], Italy; 3The Wave Innovation Group, Verona, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15355
    91
  • BIODEGRADATION OF POLYETHYLENE TEREPHTHALATE MICROPLASTIC IN THE RUMEN OF CATTLE Sonia TASSONE1, Salvatore BARBERA1, Valentina BALESTRA2, Rabeb ISSAOUI1, Hatsumi KAIHARA1, Stefania PRAGLIOLA3, Vincenzo VENDITTO3, Khalil ABID1 | 1Dipartimento di Scienze Agrarie, Forestali e Alimentari – Università di Torino; 2Dipartimento di Ingegneria dell’Ambiente, del Territorio e delle Infrastrutture, Politecnico di Torino; 3Dipartimento di Chimica e Biologia – Università di Salerno, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14536
    280
  • 061 | Immunosafe(r)-by-design invertebrate-based nanoparticles: from engineered to biogenic structures for translational nanomedicine Annalisa Pinsino1, Giovanni Perconti1, Alessia Giannetto2, Andi Alijagic3 | 1Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy; 2Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy; 3Man-Technology-Environment Research Center MTM, Orebro University, Sweden.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15313
    74
  • Antimicrobial, antifungal and antioxidant activities of bee glue ethanol and aqueous extracts

    Nabi Shariatifar, Akram Janghorban, Rezvan Rahimnia, Amir Sasan Mozaffari Nejad
    12-02-2018
    https://doi.org/10.4081/jbr.2017.6452
    1221
    Downloads: 683
  • 073 | Modulation of NLRP3 inflammasome and macrophage polarization by quantum molecular resonance in THP-1 cells Maria Giulia Di Battista1, Osama Elsallabi1, Benedetta Rizza1, Tiziano Lupi1, Alessandro Pozzato2, Paola Lanuti1, Antonia Patruno1 | 1Department of Medicine and Aging Sciences, University “G. d’Annunzio” of Chieti-Pescara, Italy; 2Telea Electronic Engineering Srl, Sandrigo [VI], Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15325
    76
  • The frequency of T regulatory cells is increased in peripheral blood of patients with colon-rectal cancer

    D. Saverino, C. Stabilini, R. SImone, E. Gianetta, F. Milintenda-Florian
    30-01-2011
    https://doi.org/10.4081/jbr.2011.4659
    922
    Downloads: 624
  • 190 | Surface engineering of titanium implants with vanillin-chitosan and cerium doped-nanoparticle coatings for improved osteoimmune response Ioannis Tsamesidis1, Styliani Axypolitou1, Georgia K. Pouroutzidou1, Maria Bousnaki1, Dimitrios Bikiaris1, Evi Christodoulou1, Antonios D. Anastasiou2, Eleana Kontonasaki1 | 1Aristotle University of Thessaloniki, Greece 2University of Manchester, UK.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15442
    99
  • Does zinc sulfate inhibit the in vitro cytotoxicity of crude toxin from Pelagia noctiluca?

    G.L. Mariottini, E. Giacco, L. Pane
    30-01-2011
    https://doi.org/10.4081/jbr.2011.4488
    1133
    Downloads: 677
  • MICROPLASTICS IN EDIBLE PLANTS: AN UNDERESTIMATED RISK IN THE HUMAN FOOD CHAIN Pasquale PERRONE, Stefania D’ANGELO | Department of Medical, Movement, and Wellbeing Sciences, Parthenope University of Naples, Naples, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14537
    688
  • 056 | Thidiazuron exposure reprograms metabolic networks with lasting effects on growth and photosynthetic efficiency in Arabidopsis thaliana Manuela Giraldo-Acosta1, Giulia Giovanna Salerno2, Marino B. Arnao1, Cinzia Margherita Bertea3, Ada Ricci2, Giuseppe Mannino3 | 1Department of Plant Biology Plant Physiology, University of Murci, Spain; 2Department of Chemical, Life and Environmental Sustainability Sciences, University of Parma, Italy; 3Department of Life Sciences and Systems Biology, Plant Physiology Unit, University of Turin, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15308
    82
  • Biological activity and chemical identification of ornithine lipid produced by Burkholderia gladioli pv. agaricicola ICMP 11096 using LC-MS and NMR analyses

    Hazem Salaheldin Elshafie, Licia Viggiani, Mohamed Said Mostafa, Maher A. El-Hashash, Ippolito Camele, Sabino Aurelio Bufo
    12-02-2018
    https://doi.org/10.4081/jbr.2017.6534
    1937
    Downloads: 1103
  • Antioxidant and antifungal activities in vitro of essential oils and extracts of twelve Algerian species of Thymus against some mycotoxigenic Aspergillus genera

    Yamina Ben Miri, Aldjia Taoudiat, Mohamed Mahdid
    11-01-2022
    https://doi.org/10.4081/jbr.2022.10299
    2657
    Downloads: 744
  • On probiotic integration in the management of inflammation and the maintenance of the intestinal epithelial barrier’s integrity

    Giovanna Traina
    08-08-2024
    https://doi.org/10.4081/jbr.2024.12362
    1186
    Downloads: 530
  • 072 | A standardized onion peel-derived bioactive ingredient attenuates palmitate-induced steatosis and oxidative stress in HepG2 cells Ilaria Di Gregorio1|2, Vincenzo Migliaccio2, Maria D’Elia1|3|4, Rita Celano1|3, Anna Lisa Piccinelli1|3, Luca Rastrelli1|3, Lillà Lionetti2|3 | 1Dept Pharmacy, University of Salerno, Salerno, Italy; 2Dept Chemistry and Biology “A Zambelli”, University of Salerno, Italy; 3National Biodiversity Future Center NBFC, Palermo, Italy; 4Dept Earth and Marine Sciences, University of Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15324
    83
  • 185 | From mycelium to medicine: cytotoxic effects of Ganoderma adspersum extracts in renal cancer cells Maria Noemi Sgobba1, Nikola Schlosserova1|2, Biagia Musio3, Federica Mastropirro1, Antonio Radesco4, Maria Favia5, Simona Marianna Sanzani4, Stefano Todisco3, Mariateresa Volpicella1, Anna De Grassi1, Vito Gallo3, Elena Ciani1, Ciro Leonardo Pierri6, Jakub Treml7, Lorenzo Guerra1 | 1Department of Biosciences, Biotechnologies and Environment, University of Bari, Italy; 2Department of Chemistry and Biochemistry, Faculty of AgriSciences, Mendel University in Brno, Czech Republic; 3Department of Civil, Environmental, Land, Building Engineering and Chemistry DICATECh, Polytechnic University of Bari, Italy; 4Department of Soil, Plant and Food Sciences, University of Bari, Italy; 5Department of Translational Biomedicine and Neurosciences DiBraiN, University of Bari, Italy; 6Department of Pharmacy – Pharmaceutical Sciences, University of Bari, Italy; 7Department of Molecular Pharmacy, Faculty of Pharmacy, Masaryk University, Brno, Czech Republic.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15437
    83
  • 016 | Mechanisms underlying resistance to CDK4/6 inhibitors in aggressive medulloblastoma subtypes Alice Foti1, Fabio Allia1, Marilena Briglia1, Gianpiero Tamburrini2, Roberta Malaguarnera1, Francesco Cecconi2|3, Vittoria Pagliarini2|3, Veronica Marabitti4, Francesca Nazio4, Adriana C.E. Graziano1 | 1University of Enna “Kore”, Enna, Italy; 2Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; 3Università Cattolica del Sacro Cuore, Rome, Italy; 4University of Rome Tor Vergata, Rome, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15268
    93
  • In vitro Assessment of Anti-Inflammatory and COX-2 inhibitory action of some medicinal plants

    Usama Ramadhan
    03-08-2020
    https://doi.org/10.4081/jbr.2020.8723
    2161
    Downloads: 944
  • Effects of PCB mixtures on recognized targets of endocrine disrupters exposure: search for early biomarkers

    L. Stecca, C. La Rocca, S. Tait, A. Mantovani
    30-01-2011
    https://doi.org/10.4081/jbr.2011.4628
    818
    Downloads: 604
  • IDENTIFICATION OF D. MELANOGASTER ENZYMES POTENTIALLY INVOLVED IN PENTACHLOROPHENOL DEGRADATION M. CASTALDO1,2, D.M. MONTI2, A. TESTA3, J. VONTAS4,5, D. TSAKIRELLI4,5, M.M. MONTI1, P.A. PEDATA1 | 1Institute for Sustainable Plant Protection (CNR-IPSP), Portici (NA), Italy; 2Department of Chemical Sciences, University of Naples “Federico II”, Naples, Italy; 3Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Caserta, Italy; 4Pesticide Science Lab, Agricultural University of Athens, Athens, Greece; 5Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Crete, Greece

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14545
    166
  • Forhidrol, a bioactive fraction of Phaleria macrocarpa (Scheff.) Boerl., increases reverse cholesterol transport pathway by down-regulation of cholesteryl ester transfer protein activity

    Guntur Berlian, Olivia M. Tandrasasmita, Dwi A.S. Suciptan, Raymond R. Tjandrawinata
    11-05-2018
    https://doi.org/10.4081/jbr.2018.6863
    1443
    Downloads: 784
  • METHYLEUGENOL AND EUGENOL VARIATION IN OCIMUM BASILICUM CV. GENOVESE GIGANTE GROWN IN GREENHOUSE AND IN VITRO

    M. MIELE, B. LEDDA, C. FALUGI, M. MAZZEI
    31-05-2024
    https://doi.org/10.4081/jbr.2001.12518
    212
    Downloads: 302
  • Effects of microgravity and cosmic radiations on human T lymphocytes

    P. Pippia, G. Galleri, M.A. Meloni, A. Saba, G. Pani, M. Cogoli-Greuter, A. Cogoli
    30-01-2011
    https://doi.org/10.4081/jbr.2009.4697
    1489
    Downloads: 821
  • NANOPLASTICS AND IMMUNITY: INVESTIGATING THE EXTRACELLULAR MATRIX’S INFLUENCE ON MACROPHAGE INTERACTION WITH POLYSTYRENE NANOPARTICLES Marianna ROCA1, Naym BLAL1, Zeynep RENKLER2, Vincenzo GUARINO2, Antonia DI MOLA1, Antonio MASSA1, Ilaria DE MARTINO3, Velia SICILIANO3, Daniela GUARNIERI1 | 1Department of Chemistry and Biology, “Adolfo Zambelli”, University of Salerno; 2Institute of Polymers, Composites and Biomaterials, National Research Council of Italy; 3Synthetic and Systems Biology for Biomedicine Lab, Istituto Italiano di Tecnologia, Naples, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14561
    255
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Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

is the official journal of the Società Italiana di Biologia Sperimentale and it is published online by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

pISSN: 1826-8838
eISSN: 2284-0230

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