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089 | Epithelial-immune cell crosstalk in salivary gland tumors: implications for tumor progression and diagnostic assessment Martina Sausa1, Giuseppe Vergilio1, Rosario Barone1, Rossana Porcasi2, Prince Ofori3, Fatima Azhraa Haddad3|4, Francesca Rappa1|5, Francesca Levi-Schaffer,3 Angelo Leone1|3 | 1Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties PROMISE, University of Palermo, Italy; 3Pharmacology and Experimental Therapeutics Unit, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel; 4Department of Otolaryngology Head and Neck Surgery, Hadassah Medical Center, Hebrew University of Jerusalem, Israel; 5Institute of Translational Pharmacology, National Research Council of Italy CNR, Palermo, Italy.
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06 | FROM MACRO- TO MICROPLASTICS IN THE SOUTHERN TYRRHENIAN SEA: AN INTEGRATED ANALYSIS OF MONITORING, IMPACTS ON BIOTA, AND MITIGATION STRATEGIES Monique Mancuso1|2, Francesca Fabrizi1|3, Ilaria Guardamagna1, Chiara Anastasia Bruno1, Teresa Bottari1|2 | 1Istituto per le Risorse Biologiche e le Biotecnologie Marine (IRBIM) - CNR, Messina, Italy; 2National Biodiversity Future Center (NBFC), Palermo, Italy; 3Scuola Universitaria Superiore IUSS Pavia, Italy
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103 | Valorization of olive mill wastewaters for the recovery of polyphenols with reducing, radical scavenging and anti-inflammatory activities Francesco Longo1, Luisa Tesoriere1, Claudio Luparello1, Ignazio Restivo1, Federica Bellistrì1, Serena Indelicato1, David Bongiorno1, Rosi De Luca1, Giulia Abruscato1, Antonio Fabbrizio2, Salvatore Terrani3, Mirella Vazzana1, Vincenzo Arizza1, Manuela Mauro1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences DiSTA, University e Campus, Novedrate [CIO], Italy; 3The Wave Innovation Group, Verona, Italy.
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151 | Dysregulation of the lung-brain axis induced by CMIT/MIT: oxidative stress and junctional protein impairment lead to α-synuclein accumulation and dopaminergic neurotoxicity Nicla Tranchida1, Rosanna Di Paola2, Marika Cordaro3 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Italy; 3Department of Biomedical, Dental and Morphological and Functional Imaging University of Messina, Italy.
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052 | Metabolic analysis of farm animal plasma by 1H-NMR: variation and preliminary spectral characterization Luca Cicero1, Silvia Orecchio1, Aldo Migliazzo1, Valeria Vitale Badaco1, Stefano Burgio3, Tiziana Orefice1, Giuseppe La Corte1, Antonino La Corte1, Grazia Scuderi2, Paolo Fagone2, Giovanni Cassata1 | 1Istituto Zooprofilattico Sperimentale della Sicilia, Italy; 2Università degli Studi di Catania, Italy; 3Università di Enna "Kore", Italy.
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111 | Plastic contamination in bycaught yelkouan shearwater (Puffinus yelkouan) from the Mediterranean sea Marco Parolini1, Federico Tossani1, Federico De Pascalis2, Dimitra Christidi3, Angelos Evangelidis3, Andrea Benvenuti4, Sara Di Leo1, Simona Mondellini1, Giacomo Dell’Omo4, Danae Portolou3, Jacopo G. Cecere2, Diego Rubolini1 | 1Department of Environmental Science and Policy, University of Milan, Italy; 2Area Avifauna Migratrice, Istituto Superiore per la Protezione e la Ricerca Ambientale ISPRA, Ozzano dell’Emilia, Italy; 3Hellenic Ornithological Society, Athens, Greece; 4Animal Tracking, TECHNOSMART EUROPE srl, Guidonia-Montecelio, Roma, Italy.
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027 | Exploring the cooperative effect of osilodrostat and mitotane in 3D spheroid models of adrenocortical carcinoma Fabiola Vaglica1, Laura Tomasello1, Mattia Biondo2, Giuseppe Siragusa2, Giorgio Arnaldi1, Giuseppe Pizzolanti1|3, Valentina Guarnotta1 | 1Dept. of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties PROMISE, University of Palermo; 2Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo; 3ATeN Center, Palermo, Italy.
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087 | Synergistic collapse of redox homeostasis in human hepatic and renal cells: perfluorooctane sulfonate as a priming factor for oxidative pathophysiology Graziano Vinci1, Marika Cordaro2, Rosanna Di Paola3 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy; 2Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy; 3Department of Veterinary Sciences, University of Messina, Italy.
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040 | Comparative neurotoxicity of glyphosate and its metabolite aminomethylphosphonic acid: evidence from Cyprinus carpio Serafina Ferrara1, Jana Blahova2, Premysl Mikula2, Petr Marsalek2, Caterina Faggio1|3 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Animal Protection and Welfare and Veterinary Public Health, University of Veterinary Sciences Brno, Brno, Czech Republic; 3Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.
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182 | Preliminary data on clinical assessment, blood biochemistry analysis, and infrared thermography in dairy cows affected by foot diseases Maria Rizzo1, Nicolò Parisi1, Andrea Spadaro1, Esterina Fazio1, Enrico Fiore2, Giorgia Taio2, Giuseppe Piccione1, Francesca Arfuso1, Filippo Spadola1 | 1Department of Veterinary Sciences, University of Messina, Polo University Annunziata, Messina, Italy; 2Department of Animal Medicine, Productions and Health MAPS, University of Padua, Legnaro, Italy;.
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102 | Polylactic acid nanoparticles as metabolically active entities: a metabolomics and fluxomics perspective Martina Lombardi1|2|3, Vera Abenante2|3, Alessio Trotta2|3, Erwin Pavel Lamparelli1, Federica Montella1, Giovanna Della Porta1, Andrea Viggiano1, Jacopo Troisi1|2|3|4, Antonietta Santoro1 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 2Theoreo Srl, Montecorvino Pugliano, Salerno, Italy; 3European Institute of Metabolomics - Fondazione EIM, Baronissi, Salerno, Italy; 4Department of Chemistry and Biology, “A Zambelli”, University of Salerno, Fisciano [SA], Italy.
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CO-EXPOSURE TO MICROPLASTICS AND CADMIUM: EFFECTS ON DNA DAMAGE IN MYTILUS GALLOPROVINCIALIS Marina PISCOPO, Giulio SANTANIELLO, Simona AMORE, Carmela MARINARO, Anna Rita BIANCHI, Martina FALACE, Bruno BERMAN, Gennaro LETTIERI, Anna DE MAIO | Dipartimento di Biologia, Università degli Studi di Napoli Federico II, Napoli, Italy
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139 | Municipal and agricultural waste is increasingly complex and impacts local biodiversity electronics integrated with ai systems can help Matteo Mottica1, Paolo Bonivento2 | 1MQuadro srl, Trieste, Italy; 2Istituto di Studi Europei “A. De Gasperi”, Roma, Italy.
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051 | Optimization of a combined spectral and imaging flow cytometry protocol integrated with AI for rapid human microbiota screening Arianna Aquilini-Mummolo1|2, Francesca D’Ascanio1|2|3, Giulia Colasante1|2, Domenico De Bellis1|2, Pasquale Simeone4, Sabino Porro1|2, Tamer Esmail1|2, Ayesha Younas1|2, Luana D’Onofrio1|2, Isabel Vallejo Bermúdez5|6, Camilla Cichella2, Mariagiulia Filoso1|2, Chiara Porro4, Paola Lanuti1|2. | 1Department of Medicine and Aging Sciences, University “G d’Annunzio”, Chieti-Pescara, Chieti; 2Center for Advanced Studies and Technology CAST, University “G d’Annunzio”, Chieti-Pescara; 3Department of Humanities, Law and Economics, “Leonardo da Vinci” University, Torrevecchia Teatina, Italy; 4Department of Clinical and Experimental Medicine, University of Foggia, Italy; 5Molecular Immunology Group CTS208, Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; 6Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain.
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110 | Integrative ultrastructural and molecular evidence of ferroptosis in lead-exposed zebrafish liver Ilaria Olivito, Abdalmoiz I.m. Ahmed, Federica Talarico, Marcello Mezzasalma, Elvira Brunelli | Department of Biology, Ecology and Earth Sciences DiBEST, University of Calabria, Rende [CS], Italy.
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025 | Protect colorectal cancer: in vitro chemopreventive effects of bronte pistachio extracts on colorectal cancer cells Graziella Serio1, Roberto Chiarelli1, Giuseppe Mannino2, Samuele Davì1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Life Sciences and Systems Biology, Innovation Centre, University of Turin, Italy.
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167 | The importance of personalized oxygen-ozone dosing in systemic therapy: algorithmic solutions for regenerative medicine Antonio Galoforo1, Paolo Bonivento2 | 1Tavolo Tecnico “Salute ed Ambiente”, Intergruppo parlamentare “One Health”, Camera dei Deputati, Roma, Italy; 2RING - ODR Research Innovation Networking Generation, Organismo di Ricerca, Milano, Italy.
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125 | Impact of 2D and 3D in vitro culture models on extracellular vesicles in human ovarian cancer Giulia Di Fazio1, Giuseppina Poppa1, Giuseppe Cammarata2, Sandra D’Ascenzo1, Vincenza Dolo1, Simona Taverna2, Ilaria Giusti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Institute of Translational Pharmacology IFT, National Research Council of Italy CNR, Palermo, Italy.
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179 | Body fat reduction in adult women: a longitudinal study after six-month Bikram yoga Federico Zoila1|2, Francesca Martina Filannino1, Maria Ida De Stefano1, Pasquale Simeone1, Daniela Cagnetta1, Antonia Cianciulli3, Melania Ruggiero3, Maria Antonietta Panaro3, Chiara Porro1 | 1Department of Clinical and Experimental Medicine, University of Foggia, Italy; 2Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy; 3Department of Biosciences, Biotechnologies and Environment, University of Bari, Italy.
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100 | Tracking polystyrene nanoplastics by raman microscopy reveals intestinal and retinal toxicity Valentina Iezzi1, Roberta Maria Ferri1, Annamaria Iannetta2, Ludovica Sulcanese2, Tommaso Silvestrini2, Vanessa D’Altilia2, Giovanni Angelozzi2, Federico Perrella3, Carino Ferrante4, Giulia Fioravanti3, Monia Perugini2, Elisabetta Benedetti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Italy; 3Department of Physical and Chemical Sciences University of L’Aquila, Italy; 4CNR-SPIN, c/o department of Physical and Chemical Sciences University of L’Aquila, Italy.
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BIODEGRADATION OF POLYETHYLENE TEREPHTHALATE MICROPLASTIC IN THE RUMEN OF CATTLE Sonia TASSONE1, Salvatore BARBERA1, Valentina BALESTRA2, Rabeb ISSAOUI1, Hatsumi KAIHARA1, Stefania PRAGLIOLA3, Vincenzo VENDITTO3, Khalil ABID1 | 1Dipartimento di Scienze Agrarie, Forestali e Alimentari – Università di Torino; 2Dipartimento di Ingegneria dell’Ambiente, del Territorio e delle Infrastrutture, Politecnico di Torino; 3Dipartimento di Chimica e Biologia – Università di Salerno, Italy
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138 | Genetic studies to investigate the taxonomic issues of Vespa velutina and Vespa orientalis, expanding in Italian urban and agricultural areas Valeria Maselli1, Mariangela Norcia1, Alessia Illiano2, Paolo Bonivento3 | 1Dipartimento di Biologia, Università degli Studi di Napoli Federico II, Napoli, Italy; 2NEW ECO srl, Trieste, Italy; 3Istituto di Studi Europei “A. De Gasperi”, Roma, Italy.
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The role of selenium in autoimmune thyroiditis
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019 | PDE5A promotes hypoxic hepatocellular carcinoma cell survival through ERK-dependent signalling Lara Lizzi, Alberto Massimi, Mara Massimi | Dept. of Life, Health and Environmental Sciences, University of L’Aquila, Italy.
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069 | Comparative analysis of inflammatory and redox responses in human and rat macrophages exposed to calcium-doped mesoporous silica nanoparticles Styliani Axypolitou1, Antonietta Ligas2, Ioannis Tsamesidis1, Georgia K. Pouroutzidou1, Pier Luigi Fiori2, Antonella Pantaleo2, Eleana Kontonasaki1 | 1Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece 2Department of Biomedical Sciences, Division of Microbiology and Virology, University of Sassari, Italy.
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03 | MICRO- AND NANOPLASTICS: A NEW UNCONVENTIONAL RISK FACTOR FOR CARDIOVASCULAR HEALTH Raffaele Marfella | Departments of Advanced Medical and Surgical Sciences, University of Naples, Italy
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122 | Tangential flow filtration enables high-yield isolation and stable characterization of grape-derived extracellular vesicles for therapeutic application Sabino Porro1|2, Tamer Esmail1|2, Francesca D’Ascanio1|2|3, Giulia Colasante1|2, Arianna Aquilini-Mummolo,1|2, Luana D’Onofrio1|2, Mariagiulia Filoso1|2, Ayesha Younas1|2, Isabel Maria Vallejo Bermudez4|5, Camilla Cichella1|2, Michela Battistelli6, Anna Piro7, Serena Veschi7, Serena Pilato7, Antonella Fontana7, Alessandro Cama7, Angelo Cichelli8, Paola Lanuti1|2, Federica Flamminii9 | 1Department of Medicine and Aging Sciences, University “G d’Annunzio” of Chieti-Pescara, Italy; 2Center for Advanced Studies and Technology CAST; 3Molecular Immunology Group CTS208 Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy; 4Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; 5Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain; 6Department of Biomolecular Sciences DISB University of Urbino Carlo Bo, Italy; 7Department of Pharmacy, University “G d’Annunzio” of Chieti-Pescara, Italy; 8Department of Innovative Technologies in Medicine & Dentistry, University “G d’Annunzio” of Chieti-Pescara, Italy; 9Department of Promotion of Human Sciences and Quality of Life, San Raffaele Telematic University, Rome, Italy.
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