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BIODEGRADABLE NANOPLASTIC: A TOOL FOR DRUG DELIVERY AND ENVIRONMENTAL CHALLENGE Enza TORINO1,2,3, Anna MENALE1, Samuele FIORENZA1,2, Simona SILVESTRI1,3 | 1University of Naples Federico II - Department of Chemical, Materials Engineering and Industrial Production; 2Interdepartmental Research Center on Biomaterial (CRIB); 3Fondazione Istituto Italiano di Tecnologia – Center for Advanced Biomaterials for Healthcare
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PLASTIC PACKAGING BETWEEN IMPACT AND INNOVATION: STRATEGIES FOR SUSTAINABLE MANAGEMENT Loredana INCARNATO | Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA)
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011 | Physicochemical and biological evaluation of IgG binding to self-assembling dendrimer nanomicelles Gabriele Cavalieri, Anna Laura La Monaca, Erik Laurini, Sabrina Pricl | Molecular Biology and Nanotechnology Laboratory - MolBNL@UniTS, Department of Engineering and Architecture - DEA, University of Trieste, Italy.
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178 | Food-borne and environmental pathogens in wild ungulates from Sicily: implications for public health at the wildlife–livestock–human interface Elisa Maria Petta1, Valeria Vaglica1, Ilenia Giacchino1, Paola Galluzzo1, Sergio Migliore1, Federico Cangialosi1, Silvia Scibetta1, Elena Lo Bue1, Martina Imburgia1, Giuseppina Chiarenza1, Ettore Napoli2, Annalisa Guercio1, Francesca Grippi1, Valeria Blanda1 | 1Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri”, Palermo, Italy; 2Department of Veterinary Sciences, University of Messina, Italy.
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05 | ENGINEERED PARTICLES IN DRUG DELIVERY AND TISSUE ENGINEERING: IMPLICATIONS FOR PUBLIC HEALTH Anna Barbara Di Stefano1, Simona Di Leo1, Mara Franza2|3, Francesca Toia1|2|3 | 1BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; 2Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; 3Section of Plastic and Reconstructive Surgery, Department of DAI chirurgico, Azienda Policlinico Paolo Giaccone, Palermo, Italy
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THE RISING THREAT: NANO AND MICROPLASTICS INFILTRATION IN URINARY AND REPRODUCTIVE SYSTEMS Luigi MONTANO | Andrology Unit and Service of Lifestyle Medicine in UroAndrology, “S. Francesco d’Assisi” Hospital, Local Health Authority (ASL) Salerno, EcoFoodFertility Project Coordi-nation Unit, Italian Network for Environmental and Reproductive Health, Oliveto Citra, Italy
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061 | Immunosafe(r)-by-design invertebrate-based nanoparticles: from engineered to biogenic structures for translational nanomedicine Annalisa Pinsino1, Giovanni Perconti1, Alessia Giannetto2, Andi Alijagic3 | 1Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy; 2Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy; 3Man-Technology-Environment Research Center MTM, Orebro University, Sweden.
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The role of selenium in autoimmune thyroiditis
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147 | Screening of novel metabotropic glutamate receptor 4-oriented molecules in an in vitro model of Parkinson’s disease Cristina Giuffré1, Miriana Scordino1, Giulia Urone1, Miriam Buttacavoli1, Alessandra Montalbano2, Marilia Barreca2, Roberta Bivacqua2, Paola Barraja2, Virginia Spano’2, Giuseppa Mudo’1, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy.
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EVALUATING ENDOCRINE AND OXIDATIVE EFFECTS OF POLYLACTIC ACID NANOPLASTICS (PLA-NPs) ON BREAST CELL MODELS Maria Denise AMICO1, Antonietta SANTORO2, Erwin Pavel LAMPARELLI2, Giovanna DELLA PORTA2, Magdalena GORSKA-PONIKOWSKA3,4,5, Francesca RAPPA1,5, Fabio BUCCHIERI1, Francesco CAPPELLO1,5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medical Chemistry, Medical University of Gdansk, Poland; 4Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Germany; 5Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
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033 | Innovative autonomous surface vehicles for enhanced welfare and continuous monitoring in sustainable aquaculture Alex Carnevale1, Ayman El Qemmah2, Rosario Sorbello3, Alessia Avolicino1 | 1DIBEST, Università della Calabria; 2DIMES, Università della Calabria; 3Dipartimento di Ingegneria Industriale e dell’Informazione, Università eCampus, Italy.
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129 | Ochratoxin and green coffee: certified analyses to prevent the presence of toxic alien microorganisms transported by logistic carriers Lorenzo Cergol1, Elena Ramalli1, Paolo Bonivento2 | 1New Eco srl, Trieste, Italy; 2Istituto di Studi Europei “A De Gasperi”, Roma, Italy.
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173 | Lab-on-chip (LOC) as a tool for parkinson disease diagnosis: preliminary evaluation of neuronal cell culture on LOC Rosanna Mallamaci1, Rosangela Cardone1, Lorenzo Guerra1, Maria Noemi Sgobba1, Marilena Ardone1, Antonio Ancona2, Annalisa Volpe2a, Stefania Caragnano2, Salvatore Petralia3, Adriana Trapani4 | 1Department of Biosciences, Biotechnologies and Environment, University of Bari “Aldo Moro”, Bari, Italy; 2Physics Department, Università degli Studi di Bari & Politecnico di Bari, Italy; 3Department of Drug and Health Sciences, University of Catania, Italy; 4Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, Bari, Italy.
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POLYSTYRENE NANOPARTICLES IN ZEBRAFISH: THEIR ROLE IN OCULAR STRESS AND LIPID METABOLIC IMBALANCE V. IEZZI1, F. PERRELLA2, S. ZUGARO1, R. M. FERRI1, A. IANNETTA3, L. SULCANESE3, T. SILVESTRINI3,4, M. PERUGINI3, E. BENEDETTI1, C. FERRANTE5 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila; 2Department of Physical and Chemical Sciences University of L’Aquila; 3Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo; 4Advanced Study “Theoretical and Applied Neuroscience” Preclinical, clinical and Translational neuroscience, University of Camerino, Italy; 5CNR-SPIN, c/o Department of Physical and Chemical Sciences University of L’Aquila, Italy
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015 | A flavonoid-rich extract of bergamot juice modulates redox homeostasis and apoptosis in colorectal cancer experimental models Martina Farina1, Alessandro Maugeri2, Michele Navarra1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Italy.
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093 | Beyond biodegradability: assessing the toxicological footprint of polylactic acid nanoplastics on zebrafish gastrointestinal tract development Francesca Chiara Cecala1, Giusy Vultaggio1, Martina Di Marco1, Alessandra Maria Vitale1, Rosario Barone1, Francesca Rappa1, Maria Denise Amico1, Erwin Pavel Lamparelli2, Giovanna Della Porta2, Antonietta Santoro2, Francesco Cappello1|4, Federica Scalia3, Marta Anna Szychlinska5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medicine and Surgery - Kore University of Enna, Italy; 4Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy; 5Department of Precision Medicine in Medical, Surgical and Critical Care MePreCC, University of Palermo, Italy.
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169 | Microbiological resistance and clinical ineffectiveness: an investigation into amoxicillin and amoxicillin/clavulanate efficacy in real-world populations Pierangela Irrera1, Gabriella Frattima1, Fabiola De Luca1, Anna Paola Capra1, Michela Campolo1, Alessio Ardizzone2, Emanuela Esposito1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy.
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UNTARGETED METABOLOMICS REVEALS GONADAL METABOLIC DISRUPTION IN MYTILUS GALLOPROVINCIALIS EXPOSED TO CADMIUM AND MICROPLASTICS Vera ABENANTE1,2, Andrea INGENITO1,2, Alessio TROTTA1,2, Giulio SANTANIELLO3, Gennaro LETTIERI3 , Marina PISCOPO3, Jacopo TROISI1,2,4 | 1Theoreo S.r.l., University of Salerno; 2European Institute of Metabolomics - Fondazione EIM, Baronissi (SA); 3Department of Biology, University of Naples Federico II, Naples; 4Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy
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012 | Anticancer activity of Orobanche crenata leaf extract in human colorectal cancer cell lines Floriana D’Angeli1, Alfio Distefano2, Laura Orlando2, Elisa Gili3, Valentina Di Salvatore4, Simone Ronsisvalle4, Ivana Roberta Romano2, Giuliana Mannino2, Debora Lo Furno2, Giovanni Giurdanella1, Giovanni Li Volti2, Carlo Genovese1 | 1Department of Medicine and Surgery, School of Medicine and Surgery, University of Enna "Kore", Enna, Italy; 2Department of Biomedical and Biotechnological Sciences, University of Catania, Italy; 3Department of Clinical and Experimental Medicine, "Regional Referral Center for Rare Lung Diseases", University, Hospital Policlinico "G. Rodolico-San Marco", University of Catania, Italy; 4Department of Health and Drug Sciences, University of Catania, Italy.
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078 | Stress-driven Dhurrin accumulation in sorghum revealed by physiological and biochemical markers Alessio Giannilivigni1, Manuela Giraldo-Acosta2, Flavia Girolami3, Stefano Giantin4, Luca Carisio4, Carlo Nebbia3, Marino Bañón Arnao2, Alberico Franzin4, Giuseppe Mannino1. | 1Department of Life Sciences and Systems Biology, Plant Physiology Unit, University of Turin, Italy; 2Department of Plant Biology Plant Physiology, University of Murcia, Spain; 3Department of Veterinary Sciences, University of Turin, Grugliasco [TO], Italy; 4Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta IZSPLV, Turin, Italy; 5Green Has Italia Spa, Plant Physiology Unit, Canale [CN], Italy.
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167 | The importance of personalized oxygen-ozone dosing in systemic therapy: algorithmic solutions for regenerative medicine Antonio Galoforo1, Paolo Bonivento2 | 1Tavolo Tecnico “Salute ed Ambiente”, Intergruppo parlamentare “One Health”, Camera dei Deputati, Roma, Italy; 2RING - ODR Research Innovation Networking Generation, Organismo di Ricerca, Milano, Italy.
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069 | Comparative analysis of inflammatory and redox responses in human and rat macrophages exposed to calcium-doped mesoporous silica nanoparticles Styliani Axypolitou1, Antonietta Ligas2, Ioannis Tsamesidis1, Georgia K. Pouroutzidou1, Pier Luigi Fiori2, Antonella Pantaleo2, Eleana Kontonasaki1 | 1Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece 2Department of Biomedical Sciences, Division of Microbiology and Virology, University of Sassari, Italy.
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164 | Analysis of the regenerative capacity and biochemical composition of pediatric platelet rich plasma in oronasal fistulas Anna Barbara Di Stefano1, Daniele Matta2, Francesca Toia1|2 | 1Department of Precision Medicine in Medical, Surgical and Critical Care, Plastic and Reconstructive Surgery Section, Palermo, Italy; 2BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, University of Palermo, Italy; 2Department of Precision Medicine in Medical, Surgical and Critical Care, Plastic and Reconstructive Surgery Section, University of Palermo, Italy.
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057 | Bioactive metabolites from antarctic sponge-associated bacteria: bioactivity and cytotoxic assessment Claudia Gravagno1|2, Stefano Putaggio2, Teresa Romeo2|3, Annamaria Russo2, Carmen Rizzo2|4, Ester Tellone2, Angelina Lo Giudice4 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2University of Messina, Italy; 3National Institute for Environmental Protection and Research, Milazzo [ME], Italy; 4National Research Council, Institute of Polar Sciences, Messina, Italy.
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MICRO- AND NANO-PLASTICS: HEALTH, DENTAL PRACTICE, AND ENVIRONMENT Giuseppina DE BENEDETTO1, Veronica FOLLIERO1, Maria Pia DI PALO1, Leonardo AULISIO1, Luca RINALDI2, Gianluigi FRANCI1, Federica DI SPIRITO1 | 1Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy; 2Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy
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062 | Enriched bioplastics with natural compounds as innovative hemocompatible biomaterials targeting red blood cells Stefano Putaggio, Annamaria Russo, Giuseppe Tancredi Patanè, Claudia Gravagno, Antonella Calderaro, Davide Barreca, Silvana Ficarra, Ester Tellone | Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy.
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159 | Innovative and sustainable strategies to recover bioactive molecules from pruning waste Giovanna Cafeo1, Marina Russo1, Alessia Arena2, Mariosimone Zoccali3, Paola Dugo1|2, Luigi Mondello1|2 | 1Messina Institute of Technology, c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Chromaleont srl, c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 3Department of Mathematical and Computer Science, Physical Sciences and Earth Sciences, University of Messina, Italy.
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