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086 | Kir4.1 channels at the crossroads of oxidative stress and presbycusis: redox imbalance, electrophysiological failure and quercetin-mediated rescue Sara Spinelli1, Alessia Remigante2, Angela Marino1, Rossana Morabito1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina, Italy.
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153 | α-synuclein regulation in brain and bone marrow is releted to the differential expression of GATA1 transcription factor Viola Velardi1, Francesca Arciprete1, Claudia Caturano,1Rosa Alba Rana1, Romina Mancinelli2, Maria Zingariello1, Giorgio Vivacqua1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy.
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134 | Living with mold: a growing problem for urban biodiversity Andrea Furlan1, Paolo Bonivento2 | 1Nanocoatings Research, Trieste, Italy; 2Istituto di Studi Europei “A. De Gasperi”, Roma, Italy.
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122 | Tangential flow filtration enables high-yield isolation and stable characterization of grape-derived extracellular vesicles for therapeutic application Sabino Porro1|2, Tamer Esmail1|2, Francesca D’Ascanio1|2|3, Giulia Colasante1|2, Arianna Aquilini-Mummolo,1|2, Luana D’Onofrio1|2, Mariagiulia Filoso1|2, Ayesha Younas1|2, Isabel Maria Vallejo Bermudez4|5, Camilla Cichella1|2, Michela Battistelli6, Anna Piro7, Serena Veschi7, Serena Pilato7, Antonella Fontana7, Alessandro Cama7, Angelo Cichelli8, Paola Lanuti1|2, Federica Flamminii9 | 1Department of Medicine and Aging Sciences, University “G d’Annunzio” of Chieti-Pescara, Italy; 2Center for Advanced Studies and Technology CAST; 3Molecular Immunology Group CTS208 Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy; 4Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; 5Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain; 6Department of Biomolecular Sciences DISB University of Urbino Carlo Bo, Italy; 7Department of Pharmacy, University “G d’Annunzio” of Chieti-Pescara, Italy; 8Department of Innovative Technologies in Medicine & Dentistry, University “G d’Annunzio” of Chieti-Pescara, Italy; 9Department of Promotion of Human Sciences and Quality of Life, San Raffaele Telematic University, Rome, Italy.
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ENVIRONMENTAL NANOPLASTIC ACCUMULATION AND NEURODEGENERATIVE DISEASE IN ANIMAL MODELS Beatrice ZARRILLI1,2, Nicola B. MERCURI2,3, Rosaria MECCARIELLO1, Ezia GUATTEO1,2 | 1University of Naples ‘Parthenope’, Department of Medical, Human Movement and Well-being Sciences, Naples, Italy; 2Experimental Neurology Laboratory, Fondazione Santa Lucia IRCCS, Rome, Italy; 3University of Rome Tor Vergata, Department of Systems Medicine, Rome, Italy
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095 | Nanoplastic as modulators of human immune responses: effect on natural killer and T cells Francesca D’Ascanio1|2|3, Isabel María Vallejo Bermúdez4|5, Domenico De Bellis1|2, Giulia Colasante,1|2, Arianna Aquilini1|2, Sabino Porro1|2, Tamer Shibl Ali Esmail1|2, Ayesha Younas1|2, Mariagiulia Filoso1|2, Luana D’Onofrio1|2, Piero Chiacchiaretta1|6, Melania Dovizio1|6, Patrizia Ballerini1|6, Piero Di Carlo1|6, Alejandra Pera4|5, Bruna Sinjiari6, Paola Lanuti1|2. | 1Center for Advanced Studies and Technology CAST, "G.d'Annunzio" University of Chieti-Pescara, Chieti, Italy; 2Department of Medicine and Aging Sciences, "G.d'Annunzio" University of Chieti-Pescara, Chieti, Italy; 3Department of Humanities, Law and Economics, “Leonardo da Vinci” University, Torrevecchia Teatina, Italy; 4Immunology and Allergy Group GC01, Instituto Maimónides de Investigación Biomédica IMIBIC, Córdoba, Spain; 5Molecular Immunology Group CTS208, Department of Cell Biology, Physiology and Immunology, University of Cordoba, , Spain; 6Department of Innovative Technologies in Medicine and Dentistry, University "G d'Annunzio" of Chieti-Pescara, Chieti, Italy.
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FROM PRISTINE TO LABORATORY-WEATHERED MICRO- AND NANOPLASTICS: INTERACTION WITH ENVIRONMENTAL CONTAMINANTS AND BIOLOGICAL EFFECTS Astrid SARACENI1, Barbara MOGNETTI1, Erika COTTONE1, Andrey Ethan RUBIN2, Maria Pia GALLO1, Yoav GOTHILF3, Ines ZUCKER2,4, Federica DAL BELLO5, Patrizia BOVOLIN1 | 1Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy; 2Porter School of Earth and Environmental Studies, Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel; 3Department of Neurobiology, The George S. Wise Faculty of Life Sciences and Sagol School of Neuroscience, Tel-Aviv University, Tel Aviv, Israel; 4School of Mechanical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel; 5Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy
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073 | Modulation of NLRP3 inflammasome and macrophage polarization by quantum molecular resonance in THP-1 cells Maria Giulia Di Battista1, Osama Elsallabi1, Benedetta Rizza1, Tiziano Lupi1, Alessandro Pozzato2, Paola Lanuti1, Antonia Patruno1 | 1Department of Medicine and Aging Sciences, University “G. d’Annunzio” of Chieti-Pescara, Italy; 2Telea Electronic Engineering Srl, Sandrigo [VI], Italy.
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051 | Optimization of a combined spectral and imaging flow cytometry protocol integrated with AI for rapid human microbiota screening Arianna Aquilini-Mummolo1|2, Francesca D’Ascanio1|2|3, Giulia Colasante1|2, Domenico De Bellis1|2, Pasquale Simeone4, Sabino Porro1|2, Tamer Esmail1|2, Ayesha Younas1|2, Luana D’Onofrio1|2, Isabel Vallejo Bermúdez5|6, Camilla Cichella2, Mariagiulia Filoso1|2, Chiara Porro4, Paola Lanuti1|2. | 1Department of Medicine and Aging Sciences, University “G d’Annunzio”, Chieti-Pescara, Chieti; 2Center for Advanced Studies and Technology CAST, University “G d’Annunzio”, Chieti-Pescara; 3Department of Humanities, Law and Economics, “Leonardo da Vinci” University, Torrevecchia Teatina, Italy; 4Department of Clinical and Experimental Medicine, University of Foggia, Italy; 5Molecular Immunology Group CTS208, Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; 6Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain.
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