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MATERNAL EXPOSURE TO ENDOCRINE DISRUPTORS AND INFANT DEVELOPMENT: FINDINGS FROM THE LIFE MILCH COHORT STUDY Silvia PATERLINI1, Maria Maddalena BRAMBILLA1, Francesca ALBERGHI2, Alessia ARDENGHI3, Mariateresa BELLANTONI1, Marta FONTANA2, Laura FILONZI3, Francesco NONNIS MARZANO3, Francesca NUTI4, Annalisa PELOSI1, Serafina PERRONE1, Silvia PETZA5, Roberta PINTUS5, Feliciana REAL-FERNANDEZ4, Vassilios FANOS5, Anna Maria PAPINI4, Maria E. STREET1,2, Paola PALANZA1 | 1Department of Medicine and Surgery, University of Parma (IT); 2Department of Obstetrics, Gynecology and Pediatrics, Azienda USL-IRCCS, Reggio Emilia (IT); 3Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma (IT); 4Department of Chemistry “Ugo Schiff”, University of Florence; 5Department of Surgical Sciences, University of Cagliari, Italy
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COMMERCIALLY-DERIVED MICROPLASTICS AFFECT EARLY LIFE STAGES IN PARACENTROTUS LIVIDUS SEA URCHIN Amalia AMATO1,2,3, Ermelinda PRATO4, Mariacristina COCCA5, Francesca BIANDOLINO4, Immacolata LIOTTA5,6, Simone GIOIA1,2,3, Roberta ESPOSITO1, Davide CARAMIELLO7, Loredana MANFRA1,8, Giovanni LIBRALATO1,2, Valerio ZUPO3, Maria COSTANTINI1 | 1Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Napoli, Italy; 2Department of Biology, University of Naples Federico II, Napoli, Italy; 3Stazione Zoologica Anton Dohrn, Department of Ecosustainable Marine Biotechnology, Ischia Marine Centre, Ischia, Italy; 4National Research Council, Water Research Institute (IRSA-CNR), Taranto, Italy; 5Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Pozzuoli, Napoli, Italy; 6Department of Chemical, Materials and Production Engineering, University of Naples “Federico II”, Napoli, Italy; 7Stazione Zoologica Anton Dohrn, Department of Marine Animal Conservation and Public Engagement, Naples, Italy; 8Institute for Environmental Protection and Research (ISPRA), Rome, Italy
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140 | The “invisible” plastic in our seafood chain: how a simple box can Sabrina Pricl1|2|3 | 1Molecular Biology and Nanotechnology Laboratory MolBNL@UniTS, Department of Engineering and Architecture DEA, University of Trieste, Italy; 2Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Poland; 3Delegate for Friuli Venezia-Giulia Region, WWF Italia, Rome, Italy;.
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02 | MICROPLASTICS ENDOCRINE-DISRUPTING CHEMICALS AND HUMAN HEALTH: METABOLIC AND REPRODUCTIVE RISKS IN A ONE HEALTH PERSPECTIVE Oliana Carnevali | Department of Life and Environmental Sciences, Università Politecnica delle Marche, Ancona, Italy
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FROM PRISTINE TO LABORATORY-WEATHERED MICRO- AND NANOPLASTICS: INTERACTION WITH ENVIRONMENTAL CONTAMINANTS AND BIOLOGICAL EFFECTS Astrid SARACENI1, Barbara MOGNETTI1, Erika COTTONE1, Andrey Ethan RUBIN2, Maria Pia GALLO1, Yoav GOTHILF3, Ines ZUCKER2,4, Federica DAL BELLO5, Patrizia BOVOLIN1 | 1Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy; 2Porter School of Earth and Environmental Studies, Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel; 3Department of Neurobiology, The George S. Wise Faculty of Life Sciences and Sagol School of Neuroscience, Tel-Aviv University, Tel Aviv, Israel; 4School of Mechanical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel; 5Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy
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113 | Ecotoxicological effects of bromuconazole in Oryzias latipes from embryos to adult endpoints Tania Russo1|2, Ilaria Olivito1, Iolanda Carratù2, Chiara Barone2, Ivan Conte2, Anna Di Cosmo2, Gianluca Polese2, Elvira Brunelli1 | 1Dipartimento di Biologia, Ecologia e Scienze della Terra, Università della Calabria, Rende [CS], Italy; 2Dipartimento di Biologia, Università di Napoli Federico II, Napoli, Italy.
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013 | Innovative therapeutic approaches in solid tumors Alessia Dottore1, Rosalba Rossello2, Francesco Ferraù1 | 1UOC Oncologia Medica, Ospedale “San Vincenzo”, Taormina [ME], Italy; 2UOS Oncologia Medica, Ospedale “Cutroni Zodda”, Barcellona Pozzo di Gotto [ME], Italy.
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PRELIMINARY RESULTS ON MICROPLASTIC AND NANOPLASTIC IMPACT IN VIRUS AND BACTERIAL REPLICATION Nicoletta CAPUANO1,2, Alessia GIANNATTASIO3, Noemi CAFA’1,2, Anna BARBATO1,2, Mariarosa SCOGNAMIGLIO4, Vincenzo BELGIORNO5, Luca RINALDI6, Veronica FOLLIERO1,2, Antonio BUONERBA3, Gianluigi FRANCI1,2 | 1Dipartimento di Medicina, Chirurgia e Odontoiatria, Scuola Medica Salernitana, Università degli Studi di Salerno, Baronissi (SA), Italia; 2UOS di Microbiologia e Virologia, AOU San Giovanni di Dio e Ruggi D’Aragona, Salerno, Italia; 3Dipartimento di Chimica e Biologia, Università degli Studi di Salerno, Fisciano (SA), Italia; 4Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA), Italia; 5Dipartimento di Ingegneria Civile, Università degli Studi di Salerno, Fisciano (SA), Italia; 6Dipartimento di Medicina e Scienze della Salute, Università degli Studi del Molise, Italy
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056 | Thidiazuron exposure reprograms metabolic networks with lasting effects on growth and photosynthetic efficiency in Arabidopsis thaliana Manuela Giraldo-Acosta1, Giulia Giovanna Salerno2, Marino B. Arnao1, Cinzia Margherita Bertea3, Ada Ricci2, Giuseppe Mannino3 | 1Department of Plant Biology Plant Physiology, University of Murci, Spain; 2Department of Chemical, Life and Environmental Sustainability Sciences, University of Parma, Italy; 3Department of Life Sciences and Systems Biology, Plant Physiology Unit, University of Turin, Italy.
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PLASTIC PACKAGING BETWEEN IMPACT AND INNOVATION: STRATEGIES FOR SUSTAINABLE MANAGEMENT Loredana INCARNATO | Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA)
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01 | INTEGRATED STRATEGIES FOR PLASTIC MANAGEMENT: MONITORING, BIOLOGICAL IMPACT, AND CIRCULAR PERSPECTIVES ROUND TABLE REPORT Giorgia Görner Enrile1|2, Antonietta Santoro3, Federica Scalia4, Stefania D’Angelo5, Annamaria Visco6, Andrea Pace7, Michele Torregrossa8, Dario Scalia9, Alessandro Aglialoro10, Salvatore Campanella10 | 1Siciliamedica.it; 2Ilsicilia.it; 3PI, Plastamination Project, University of Salerno, Italy; 4Human Anatomy, University Kore, Enna, Italy; 5Biochemistry, University Parthenope of Naples, Italy; 6Life Restart Project, University of Messina, Italy; 7Research and Technology Transfer, University of Palermo, Italy; 8Engineering, University of Palermo, Italy; 9Plastic Free Onlus Sicily, Italy; 10Regional Environmental Protection Agency of Sicily, Italy
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019 | PDE5A promotes hypoxic hepatocellular carcinoma cell survival through ERK-dependent signalling Lara Lizzi, Alberto Massimi, Mara Massimi | Dept. of Life, Health and Environmental Sciences, University of L’Aquila, Italy.
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044 | Thyroid response to stress in illness Caretta caretta: a preliminary study Chiara Lomonaco1, Paola Galluzzo2|3, Giorgia Schirò1|3, Angelo Costanza2|3, Rosario Adragna3, Vincenzo Monteverde2|3, Claudia Giannetto1, Salvatore Dara2|3, Rosaria Disclafani2|4 | 1Dipartimento di Scienze Veterinarie, Polo Universitario dell’Annunziata, University of Messina, Italy; 2Centro Referenza Nazionale per il Benessere, Monitoraggio e Diagnostica delle malattie delle Tartarughe Marine CReTaM; 3Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri”, Palermo, Italy; 4Centro di Sostenibilità e Transizione Ecologica, University of Palermo, Italy.
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125 | Impact of 2D and 3D in vitro culture models on extracellular vesicles in human ovarian cancer Giulia Di Fazio1, Giuseppina Poppa1, Giuseppe Cammarata2, Sandra D’Ascenzo1, Vincenza Dolo1, Simona Taverna2, Ilaria Giusti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Institute of Translational Pharmacology IFT, National Research Council of Italy CNR, Palermo, Italy.
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076 | Iron-driven redox dysregulation fuels psoriatic signaling in CARD14 e138a mutant keratinocytes Cristiana Galeano1, Anna Martina Battaglia1, Emanuele Giorgio1, Lavinia Petriaggi1, Giuseppe Natali2, Flavia Biamonte1 | 1Laboratory of Biochemistry and Cell Biology, Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Italy; 2Department of Life Science, Magna Graecia University of Catanzaro, Italy.
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ISSUE INFORMATION Program | Committees | Sponsors |
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POLYSTYRENE NANOPARTICLES IN ZEBRAFISH: THEIR ROLE IN OCULAR STRESS AND LIPID METABOLIC IMBALANCE V. IEZZI1, F. PERRELLA2, S. ZUGARO1, R. M. FERRI1, A. IANNETTA3, L. SULCANESE3, T. SILVESTRINI3,4, M. PERUGINI3, E. BENEDETTI1, C. FERRANTE5 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila; 2Department of Physical and Chemical Sciences University of L’Aquila; 3Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo; 4Advanced Study “Theoretical and Applied Neuroscience” Preclinical, clinical and Translational neuroscience, University of Camerino, Italy; 5CNR-SPIN, c/o Department of Physical and Chemical Sciences University of L’Aquila, Italy
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106 | Health effects of noise pollution on juvenile crustaceans: behavioral and molecular responses in Procambarus clarkii Maria Ceraulo1|2, Giuseppa Buscaino1, Clarissa De Vita1, Aiti Vizzini2|3|*, Mirella Vazzana2|3, Elena Papale1, Vincenzo Arizza2|3, Francesco Longo3, Francesco Paolo Faraone3, Manuela Mauro2|3 | 1Institute for the Study of Anthropogenic impacts and Sustainability in the marine environment, National Research Council of Italy, Torretta Granitola, Campobello di Mazara [TP], Italy; 2NBFC, National Biodiversity Future Center, Palermo, Italy; 3Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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039 | Age and growth of the mesopelagic fish Electrona risso (myctophidae) from the Strait of Messina (central Mediterranean sea) Calogero Fontana1, Alice Vaccaro2, Francesco Longo1, Danilo Malara3, Emanuela Fanelli2|4, Pietro Battaglia1|4 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2Università Politecnica delle Marche UNIVPM, Dipartimento di Scienze della Vita e dell’Ambiente, Ancona, Italy; 3Northern Territory Government of Australia, Department of Agriculture and Fisheries, Fisheries Division, Berrimah, NT, Australia; 4National Biodiversity Future Center, Palermo, Italy.
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123 | Characterization of extracellular vesicles from the insect Hermetia illucens, a potential source of bioactive molecules Sharon Catrin Raimondi1, Kristian Riolo1, Domenico Savastano2, Sabrina Oliva1, Jessica Maria Abbate1, Antonio Leonardi1, Alessia Irrera3, Annalisa Pinsino4, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Progetto Hermetia, Gioia Tauro, Reggio Calabria, Italy; 3CNR IMM sede di Messina, Messina, Italy; 4Institute of Translational Pharmacology IFT National Research Council CNR, Palermo, Italy.
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189 | Fluorescent analysis by confocal microscopy of lipid droplets as a marker of oocyte quality in Sarda sheep under different seasonal conditions Silvia Zaccardi1, Domenica Cocciolone1, Guido Macchiarelli1, Sara Succu2, Giovanni Giuseppe Leoni3, Maria Grazia Palmerini1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Veterinary Medicine, University of Sassari, Italy; 3Department of Biomedical Sciences, University of Sassari, Italy.
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010 | Combining a gemcitabine-derived prodrug, GEM-C18, with nanoparticles to counteract acidic ph-dependent chemoresistance of pancreatic adenocarcinoma Francesca Fracasso, Marilena Ardone, Tiago Miguel Amaral Carvalho1|2, Barbara Rolando3, Silvia Arpicco3, Valeria Bincoletto3, Francesca Bianco4, Alessandra Fiorio Pla4, Daniela Isabel Abbrescia5, Ylenia Antonacci5, Chrysovalentinos Pousis5, Sharon Natasha Cox1, Flaviana Marzano5, Graziano Pesole1, Apollonia Tullo5, Stephan Joel Reshikn1, Rosa Angela Cardone1 | 1Dept of Biosciences, Biotechnology and Environment, University of Bari, ltaly; 2CICS-UBI-Health Sciences Research Center, Universidade da Beira Interior, Covilhã, Portugal; 3Dept. of Drug Science and Technology, University of Turin, ltaly; 4Dept of Life Sciences and Systems Biology, University of Turin, Italy 5Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies – IBIOM - CNR, Bari, Italy.
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PERINATAL EXPOSURE TO BISPHENOL A AND BISPHENOL B CAN ALTER THE SEXUAL BEHAVIOUR AND REPRODUCTIVE SYSTEM OF OFFSPRING Elena RICCI1,2, Marilena MARRAUDINO1,2, Noemi CADORIN1, Iva SABOVIC3, Alberto FERLIN3, Stefano GOTTI1,2 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Torino, Italy; 2Department of Neuroscience ‘Rita Levi Montalcini’, University of Torino, Torino, Italy; 3Department of Medicine, Operative Unit of Andrology and Medicine of Human Reproduction, University of Padova, Padova, Italy
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105 | The invasive crab Callinectes sapidus as a model for assessing sub-lethal effects of polyvinyl alcohol Alessandra Maganza1|2, Alice Gabetti1, Camilla Mossotto1|2, Alessia Merialdi1, Monia Renzi3, Francesca Provenza4, Serena Anselmi4, Antonia Concetta Elia2, Giorgia Zicarelli1, Annalisa Cotugno1, Giuseppe Esposito1, Caterina Faggio5|6, Marino Prearo1, Paolo Pastorino1 | 1The Veterinary Medical Research Institute for Piemonte, Liguria and Valle d’Aosta, Torino, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy; 3Bioscience Research Center, Orbetello, Italy; 4Department of Life Sciences, University of Trieste, Trieste, Italy; 5Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 6Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Napoli, Italy.
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035 | Shkodra lake – Drini river basin and buna in UNESCO Transboundary Biosphere Reserve: values to be protected and used in a sustainable way Aurora Dibra, Neira Medja, Irida Zmijanej, Gjergj Shegaj | University of Shkodra “Luigj Gurakuqi” Faculty of Natural Sciences, Tirana, Albania.
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MICRO- AND NANO-PLASTICS: HEALTH, DENTAL PRACTICE, AND ENVIRONMENT Giuseppina DE BENEDETTO1, Veronica FOLLIERO1, Maria Pia DI PALO1, Leonardo AULISIO1, Luca RINALDI2, Gianluigi FRANCI1, Federica DI SPIRITO1 | 1Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy; 2Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy
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122 | Tangential flow filtration enables high-yield isolation and stable characterization of grape-derived extracellular vesicles for therapeutic application Sabino Porro1|2, Tamer Esmail1|2, Francesca D’Ascanio1|2|3, Giulia Colasante1|2, Arianna Aquilini-Mummolo,1|2, Luana D’Onofrio1|2, Mariagiulia Filoso1|2, Ayesha Younas1|2, Isabel Maria Vallejo Bermudez4|5, Camilla Cichella1|2, Michela Battistelli6, Anna Piro7, Serena Veschi7, Serena Pilato7, Antonella Fontana7, Alessandro Cama7, Angelo Cichelli8, Paola Lanuti1|2, Federica Flamminii9 | 1Department of Medicine and Aging Sciences, University “G d’Annunzio” of Chieti-Pescara, Italy; 2Center for Advanced Studies and Technology CAST; 3Molecular Immunology Group CTS208 Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy; 4Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; 5Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain; 6Department of Biomolecular Sciences DISB University of Urbino Carlo Bo, Italy; 7Department of Pharmacy, University “G d’Annunzio” of Chieti-Pescara, Italy; 8Department of Innovative Technologies in Medicine & Dentistry, University “G d’Annunzio” of Chieti-Pescara, Italy; 9Department of Promotion of Human Sciences and Quality of Life, San Raffaele Telematic University, Rome, Italy.
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054 | Biostimulant-mediated mitigation of hypoxic stress and recovery in lettuce under flooding conditions Chiara Dellapiana1, Chiara Agliassa2, Francesco Caldo1, Moez Maghrebi1, Valeria Contartese2, Giuseppe Mannino1, Gianpiero Vigani1 | 1Department of Life Sciences and Systems Biology, University of Turin, Italy; 2Green Has Italia SpA, Canale [AT], Italy.
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184 | Phytochemicals in pruning waste and food industry by-products: biodiversity and circular economy Marina Russo1, Giovanna Cafeo1, Luigi Mondello1|2, Paola Dugo1|2 | 1Messina Institute of Technology c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, former Veterinary School, University of Messina, Italy; 2Chromaleont srl, c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, former Veterinary School, University of Messina, Italy.
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002 | Ecotoxicology in a changing planet: challenges and opportunities in the Anthropocene Paolo Pastorino1, Antonia Concetta Elia2, Monia Renzi3, Caterina Faggio4|5, Marino Prearo1, Damià Barceló6 | 1Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Torino, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy; 3Department of Life Sciences, University of Trieste, Italy; 4Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 5Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy; 6Department of Chemistry and Physics, University of Almería, Carretera Sacramento, Almería, Spain.
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EXPOSITION TO PLASTIC AND ASSOCIATED-CHEMICALS IN NEURODEVELPMENTAL DISORDER: AN OVERVIEW Grazia Maria Giovanna PASTORINO, Francesca Felicia OPERTO | Department of Science of Health School of Medicine, University Magna Greacia of Catanzaro, Italy
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100 | Tracking polystyrene nanoplastics by raman microscopy reveals intestinal and retinal toxicity Valentina Iezzi1, Roberta Maria Ferri1, Annamaria Iannetta2, Ludovica Sulcanese2, Tommaso Silvestrini2, Vanessa D’Altilia2, Giovanni Angelozzi2, Federico Perrella3, Carino Ferrante4, Giulia Fioravanti3, Monia Perugini2, Elisabetta Benedetti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Italy; 3Department of Physical and Chemical Sciences University of L’Aquila, Italy; 4CNR-SPIN, c/o department of Physical and Chemical Sciences University of L’Aquila, Italy.
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028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale1, Giuseppa D’Amico1, Martina Di Marco1, Giuseppina Poppa2, Pierlorenzo Maria Veiceschi3, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Paola Limoncelli2, Ilaria Giusti2, Vincenza Dolo2, Claudia Campanella1, Francesca Rappa1, Rosario Barone1, Giovanni Tringali3, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.
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117 | Modulation of DNA methylation patterns and heat shock proteins following exercise and probiotic supplementation A. Boatta1|2, G. Messina1, A. Pagliaro3, A. Alioto3, C. Rossi3, L. Paladino4, F. Rappa6, F. Naselli5, F. Cappello6, R. Barone6, P. Proia3 | 1Department of Human Sciences and Promotion of Quality of Life, San Raffaele Roma Open University, Roma, Italy; 2Institute for Biomedical Research and Innovation, CNR, Palermo, Italy; 3Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Sciences and Human Movement, University of Palermo, Palermo, Italy; 4Department of Theoretical and Applied Sciences DiSTA, eCampus University, Novedrate, Italy; 5Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy; 6Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Palermo, Italy.
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