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057 | Bioactive metabolites from antarctic sponge-associated bacteria: bioactivity and cytotoxic assessment Claudia Gravagno1|2, Stefano Putaggio2, Teresa Romeo2|3, Annamaria Russo2, Carmen Rizzo2|4, Ester Tellone2, Angelina Lo Giudice4 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2University of Messina, Italy; 3National Institute for Environmental Protection and Research, Milazzo [ME], Italy; 4National Research Council, Institute of Polar Sciences, Messina, Italy.
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062 | Enriched bioplastics with natural compounds as innovative hemocompatible biomaterials targeting red blood cells Stefano Putaggio, Annamaria Russo, Giuseppe Tancredi Patanè, Claudia Gravagno, Antonella Calderaro, Davide Barreca, Silvana Ficarra, Ester Tellone | Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy.
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106 | Health effects of noise pollution on juvenile crustaceans: behavioral and molecular responses in Procambarus clarkii Maria Ceraulo1|2, Giuseppa Buscaino1, Clarissa De Vita1, Aiti Vizzini2|3|*, Mirella Vazzana2|3, Elena Papale1, Vincenzo Arizza2|3, Francesco Longo3, Francesco Paolo Faraone3, Manuela Mauro2|3 | 1Institute for the Study of Anthropogenic impacts and Sustainability in the marine environment, National Research Council of Italy, Torretta Granitola, Campobello di Mazara [TP], Italy; 2NBFC, National Biodiversity Future Center, Palermo, Italy; 3Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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058 | Interaction between cyclic peptides and lipids: spectroscopic, calorimetric and structural analysis Anna Laura La Monaca, Gabriele Cavalieri, Erik Laurini, Sabrina Pricl | Molecular Biology and Nanotechnology Laboratory MolBNL@UniTs, Department of Engineerig and Architecture DEA, University of Trieste, Italy.
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040 | Comparative neurotoxicity of glyphosate and its metabolite aminomethylphosphonic acid: evidence from Cyprinus carpio Serafina Ferrara1, Jana Blahova2, Premysl Mikula2, Petr Marsalek2, Caterina Faggio1|3 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Animal Protection and Welfare and Veterinary Public Health, University of Veterinary Sciences Brno, Brno, Czech Republic; 3Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.
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IDENTIFICATION OF D. MELANOGASTER ENZYMES POTENTIALLY INVOLVED IN PENTACHLOROPHENOL DEGRADATION M. CASTALDO1,2, D.M. MONTI2, A. TESTA3, J. VONTAS4,5, D. TSAKIRELLI4,5, M.M. MONTI1, P.A. PEDATA1 | 1Institute for Sustainable Plant Protection (CNR-IPSP), Portici (NA), Italy; 2Department of Chemical Sciences, University of Naples “Federico II”, Naples, Italy; 3Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Caserta, Italy; 4Pesticide Science Lab, Agricultural University of Athens, Athens, Greece; 5Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Crete, Greece
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025 | Protect colorectal cancer: in vitro chemopreventive effects of bronte pistachio extracts on colorectal cancer cells Graziella Serio1, Roberto Chiarelli1, Giuseppe Mannino2, Samuele Davì1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Life Sciences and Systems Biology, Innovation Centre, University of Turin, Italy.
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118 | Perinatal tissue-derived extracellular vesicles for diabetic wound healing: a translational proposal Mattia Biondo1, Laura Tomasello2, Giuseppina Biscari1, Grazia L. Di Grado2, Calogero Fiorica1, Fabio S. Palumbo1, Marian Mellen3, Ismael Santa-Maria3, Antonio S. Laganà2, Maite Iglesias3, Giovanna Pitarresi1, Giuseppe Pizzolanti2|4 | 1Dept of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; 2Dept of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties PROMISE, University of Palermo, Italy; 3Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Madrid, Spain; 4ATeN Center, Palermo, Italy.
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124 | Immunomodulatory effects of extracellular vesicles from invertebrate species on human cells Kristian Riolo1, Francesco Di Pietro1, Sabrina Oliva1, Claudia Mosca1, Valeria Stefanizzi1, Giovanna Montana2, Annalisa Pinsino2, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy.
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031 | Hypoxia exposure influences the oxidative status of Mytilus galloprovincialis in a time-dependent manner Alessia Caferro1, Mariacristina Filice1, Giorgia Giurlanda1, Maria Assunta Iovine1, Alfonsina Gattuso1, Federica Impellitteri2, Caterina Faggio3, Maria Carmela Cerra1, Sandra Imbrogno1 | 1 Department of Biology, Ecology, and Earth Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy; 2 Department of Veterinary Sciences, University of Messina, Italy; 3 Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.
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021 | Novel para-phenylenediamine-based derivatives as receptor tyrosine kinase-like orphan receptor 1 inhibitors: an in vitro preliminary characterization Maria Rosaria Miranda1, Gerardina Smaldone1, Francesca Di Matteo1, Valeria Napolitano1, Michela Aliberti1, Simona Musella1, Veronica Di Sarno1, Gianluigi Lauro1, Giuseppe Bifulco1, Giacomo Pepe1, Giovanna Aquino1, Mario Felice Tecce1, Isabel Maria Gomez-Monterrey2, Pietro Campiglia1, Carmine Ostacolo1, Alessia Bertamino1, Tania Ciaglia1, Vincenzo Vestuto1 | 1Department of Pharmacy, University of Salerno, Italy; 2Department of Pharmacy, University of Naples Federico II, Naples, Italy.
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103 | Valorization of olive mill wastewaters for the recovery of polyphenols with reducing, radical scavenging and anti-inflammatory activities Francesco Longo1, Luisa Tesoriere1, Claudio Luparello1, Ignazio Restivo1, Federica Bellistrì1, Serena Indelicato1, David Bongiorno1, Rosi De Luca1, Giulia Abruscato1, Antonio Fabbrizio2, Salvatore Terrani3, Mirella Vazzana1, Vincenzo Arizza1, Manuela Mauro1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences DiSTA, University e Campus, Novedrate [CIO], Italy; 3The Wave Innovation Group, Verona, Italy.
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162 | Functional and health-promoting properties of EVOO from Sicilian olive cultivars: focus on oxidative stress and inflammation Mariateresa Cristani1, Ali Mert Yetisgin2, Giovanni Bartolomeo3, Nicola Cicero3|4, Rosaria Costa3, Nicola Micale1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2İnönü University, Faculty of Pharmacy, Kampüs, Battalgazi/Malatya, Türkiye; 3Department of Biomedical, Dental, Morphological and Functional Images Sciences BIOMORF, University of Messina, Messina, Italy; 4Science4Life srl, start-up of the University of Messina, Messina, Italy.
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049 | CMIT as an emerging contaminant: physiological and biochemical effects in Mytilus galloprovincialis Giuseppe Stracuzzi1, Federica Impellitteri1, Maria Giovanna Rizzo1, Monia Perugini2, Marika Cordaro3, Kateryna Yunko4, Oksana Stoliar4, Caterina Faggio1|5 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Feed and Food Scienxes, Teramo Univesity, Teramo, Italy; 3Department of Biomedical, Dental and Morphological and Functional Imaging University of Messina, Messina, Italy; 4Ternopil Volodymyr Hnatiuk National Pedagogical University, Ternopil, Ukraine; 5Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.
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141 | An inverted taxonomic approach unveils diversity of cladophoraceae (Chlorophyta) in two nature oriented reserves in northern Sicily (Italy) Matteo Vita1, Vincenzo Zammuto1, Mattia Soppelsa1, Fabio Mondello1, Salvatore Giacobbe2, Marina Morabito1, Antonio Manghisi1 | 1Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2CNR-IRBIM, Messina, Italy.
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068 | In vitro modulation of inflammatory mediators by eggplant peel extracts from two cultivar Alessandra Armeli, Desirèe Bonfiglio, Serena Munaò, Giovanna Calabrese | Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy.
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190 | Surface engineering of titanium implants with vanillin-chitosan and cerium doped-nanoparticle coatings for improved osteoimmune response Ioannis Tsamesidis1, Styliani Axypolitou1, Georgia K. Pouroutzidou1, Maria Bousnaki1, Dimitrios Bikiaris1, Evi Christodoulou1, Antonios D. Anastasiou2, Eleana Kontonasaki1 | 1Aristotle University of Thessaloniki, Greece 2University of Manchester, UK.
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011 | Physicochemical and biological evaluation of IgG binding to self-assembling dendrimer nanomicelles Gabriele Cavalieri, Anna Laura La Monaca, Erik Laurini, Sabrina Pricl | Molecular Biology and Nanotechnology Laboratory - MolBNL@UniTS, Department of Engineering and Architecture - DEA, University of Trieste, Italy.
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109 | Novel eco-sustainable approaches to prevent and mitigate emerging contaminants-induced physiological changes in a marine model organisms Cristiana Roberta Multisanti1, Marina Russo2, Paolo Pastorino3, Giuseppe Piccione1, Federica Impellitteri1, Caterina Faggio4|5 | 1Dept of Veterinary Sciences, University of Messina, Messina, Italy; 2Dept of Chemical, Biological, Pharmaceutical, and Environmental Sciences, Messina Institute of Technology c/o, University of Messina, Messina, Italy; 3Zooprophylactic Institute of Piedmont, Liguria and Valle d'Aosta, Turin, Italy; 4Dept of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 5Dept of Eco-sustainable Marine Biotechnology, SZN Anton Dohrn, Naples, Italy.
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105 | The invasive crab Callinectes sapidus as a model for assessing sub-lethal effects of polyvinyl alcohol Alessandra Maganza1|2, Alice Gabetti1, Camilla Mossotto1|2, Alessia Merialdi1, Monia Renzi3, Francesca Provenza4, Serena Anselmi4, Antonia Concetta Elia2, Giorgia Zicarelli1, Annalisa Cotugno1, Giuseppe Esposito1, Caterina Faggio5|6, Marino Prearo1, Paolo Pastorino1 | 1The Veterinary Medical Research Institute for Piemonte, Liguria and Valle d’Aosta, Torino, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy; 3Bioscience Research Center, Orbetello, Italy; 4Department of Life Sciences, University of Trieste, Trieste, Italy; 5Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 6Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Napoli, Italy.
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012 | Anticancer activity of Orobanche crenata leaf extract in human colorectal cancer cell lines Floriana D’Angeli1, Alfio Distefano2, Laura Orlando2, Elisa Gili3, Valentina Di Salvatore4, Simone Ronsisvalle4, Ivana Roberta Romano2, Giuliana Mannino2, Debora Lo Furno2, Giovanni Giurdanella1, Giovanni Li Volti2, Carlo Genovese1 | 1Department of Medicine and Surgery, School of Medicine and Surgery, University of Enna "Kore", Enna, Italy; 2Department of Biomedical and Biotechnological Sciences, University of Catania, Italy; 3Department of Clinical and Experimental Medicine, "Regional Referral Center for Rare Lung Diseases", University, Hospital Policlinico "G. Rodolico-San Marco", University of Catania, Italy; 4Department of Health and Drug Sciences, University of Catania, Italy.
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104 | In vitro crosstalk between perfluorooctanoic acid–induced hypertrophic adipocytes and MCF-7 breast cancer cells Maria Sofia Molonia1, Federica Lina Salamone1|2, Santi Trischitta1, Antonella Saija1, Antonio Speciale1, Francesco Cimino1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 2Imbesi Foundation, Messina, Italy.
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091 | Increased vulnerability to experimental colitis following chronic low-dose exposure to Sicilian environmental contaminants Noemi Aloi1|2, Paolo Colombo2, Valeria Longo2, Rosa Serio1, Maria Grazia Zizzo1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, Università di Palermo, Italy; 2Institute for Biomedical Research and Innovation, National Research Council of Italy IRIB-CNR, Palermo, Italy.
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079 | Pharmacological modulation of the STING pathway as an antiviral strategy against HSV-1 Federica Mastrolembo Barnà1|2, Paola Trischitta1|2, Marianna Costa1|2, Antonella Torre3, Alessia Onali3, Angela Pagliaro3, Alberto Deplano3, Elias Maccioni3, Rita Meleddu3, Simona Distinto3, Rosamaria Pennisi1, Maria Teresa Sciortino1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Dep of chemistry, biology and biotechnology, University of Perugia, Italy; 3Department of Life and Environmental Sciences, Section of Drug Sciences, University of Cagliari, University Campus, Monserrato [CA], Italy.
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086 | Kir4.1 channels at the crossroads of oxidative stress and presbycusis: redox imbalance, electrophysiological failure and quercetin-mediated rescue Sara Spinelli1, Alessia Remigante2, Angela Marino1, Rossana Morabito1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina, Italy.
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117 | Modulation of DNA methylation patterns and heat shock proteins following exercise and probiotic supplementation A. Boatta1|2, G. Messina1, A. Pagliaro3, A. Alioto3, C. Rossi3, L. Paladino4, F. Rappa6, F. Naselli5, F. Cappello6, R. Barone6, P. Proia3 | 1Department of Human Sciences and Promotion of Quality of Life, San Raffaele Roma Open University, Roma, Italy; 2Institute for Biomedical Research and Innovation, CNR, Palermo, Italy; 3Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Sciences and Human Movement, University of Palermo, Palermo, Italy; 4Department of Theoretical and Applied Sciences DiSTA, eCampus University, Novedrate, Italy; 5Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy; 6Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Palermo, Italy.
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064 | Sustainable extraction and functional characterization of bioactive compounds from Spirulina platensis for nutraceutical and cosmetic applications Carmen Sica1, Chiara Copat1, Gea Oliveri Conti1, Sheima Inoubli2, Margherita Ferrante1 | 1Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Italy; 2Department of Chemical Engineering, Universidade de Vigo, Campus de Ourense, Spain.
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099 | Mechanistic insights into the ecotoxicity of bisphenol analogues and their mixtures in marine mussels: oxidative stress and neuro-immune responses Antonella Iaconis1, Marika Cordaro2, Davide Di Paola1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 2Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina,, Italy.
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022 | Physiologic remodelling in 3D hepatocellular carcinoma models: temporal evolution from day 0 to day 9 Serena Munaò, Alessandra Armeli, Desirèe Bonfiglio, Giovanna Calabrese | Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences ChiBioFarAm, University of Messina, Italy.
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MARINE POLLUTION: MYTILUS GALLOPROVINCIALIS AS A MODEL ORGANISM TO ASSESS MICRO- AND NANOPLASTIC IMPACT Palma SIMONIELLO1, Rossana ROMANO1, Vincenzo MIGLIACCIO2, Gaetana NAPOLITANO1, Lilla LIONETTI2, Luigi ROSATI3, Chiara M. MOTTA3 | 1Department of Science and Technology, Parthenope University of Naples; 2Department of Chemistry and Biology “Adolfo Zambelli”, University of Salerno; 3Department of Biology, University of Naples Federico II, Italy
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123 | Characterization of extracellular vesicles from the insect Hermetia illucens, a potential source of bioactive molecules Sharon Catrin Raimondi1, Kristian Riolo1, Domenico Savastano2, Sabrina Oliva1, Jessica Maria Abbate1, Antonio Leonardi1, Alessia Irrera3, Annalisa Pinsino4, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Progetto Hermetia, Gioia Tauro, Reggio Calabria, Italy; 3CNR IMM sede di Messina, Messina, Italy; 4Institute of Translational Pharmacology IFT National Research Council CNR, Palermo, Italy.
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081 | Redox imbalance and ER stress mediate the anti-cancer effects of quinoline-based derivatives in triple-negative breast cancer cells Chiara Occhipinti1, Gabriele La Monica2, Federica Alamia2, Alessia Bono2, Antonino Lauria2, Annamaria Martorana2, Antonella D’Anneo1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, Laboratory of Biochemistry, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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101 | Physiological and cellular responses of the Mediterranean mussel to antifouling biocides 2-n-octyl-4-isothiazolin-3-one and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one, alone and in mixture Federica Impellitteri1, Maria Giovanna Rizzo1, Giuseppe Piccione2, Paolo Pastorino3, Cristiana Roberta Multisanti2, Caterina Faggio1|4 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Messina, Italy; 3Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Torino, Italy; 4Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.
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129 | Ochratoxin and green coffee: certified analyses to prevent the presence of toxic alien microorganisms transported by logistic carriers Lorenzo Cergol1, Elena Ramalli1, Paolo Bonivento2 | 1New Eco srl, Trieste, Italy; 2Istituto di Studi Europei “A De Gasperi”, Roma, Italy.
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159 | Innovative and sustainable strategies to recover bioactive molecules from pruning waste Giovanna Cafeo1, Marina Russo1, Alessia Arena2, Mariosimone Zoccali3, Paola Dugo1|2, Luigi Mondello1|2 | 1Messina Institute of Technology, c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Chromaleont srl, c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 3Department of Mathematical and Computer Science, Physical Sciences and Earth Sciences, University of Messina, Italy.
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047 | Halophila stipulacea: population dynamics in the oriented nature reserve “Laghetti di Marinello”, Sicily, Italy Ilaria Nusco1, Mattia Soppelsa1, Fabio Mondello1, Antonio Manghisi1, Salvatore Giacobbe2, Marina Morabito1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2CNR-IRBIM, Messina, Italy.
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097 | Pharmaceutical pollution in aquatic environments: effects of valsartan on Mytilus galloprovincialis Giorgia Giurlanda1, Alessia Caferro1, Mariacristina Filice1, Maria Assunta Iovine1, Alfonsina Gattuso1, Federica Impellitteri2, Caterina Faggio3, Maria Carmela Cerra1, Sandra Imbrogno1 | 1Department of Biology, Ecology, and Earth Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy; 2Department of Veterinary Sciences, University of Messina, Italy; 3Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.
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166 | Attenuation of Pseudomonas aeruginosa virulence by engineered phage Domenico Franco1, Salvatore Papasergi2, Francesco Mediati1, Salvatore P.P. Guglielmino1, Laura Maria De Plano1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy; 2Institute of Translational Pharmacology of the National Research Council; 3Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers’Compensation Authority INAIL, Italy.
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DEGRADATION PATHWAYS OF BIODEGRADABLE FILMS IN AQUATIC ECOSYSTEMS: THE ROLE OF ENVIRONMENTAL FACTORS IN MICROPLASTICS FORMATION Annalisa APICELLA, Loredana INCARNATO | Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA), Italy
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