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07 | WASTEWATER TREATMENT PLANTS AS A BARRIER AND SOURCE OF MICROPLASTICS Santo Fabio Corsino, Giuseppe Beringheli, Marco Capodici, Michele Torregrossa | Department of Engineering, University of Palermo, Italy
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013 | Innovative therapeutic approaches in solid tumors Alessia Dottore1, Rosalba Rossello2, Francesco Ferraù1 | 1UOC Oncologia Medica, Ospedale “San Vincenzo”, Taormina [ME], Italy; 2UOS Oncologia Medica, Ospedale “Cutroni Zodda”, Barcellona Pozzo di Gotto [ME], Italy.
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01 | INTEGRATED STRATEGIES FOR PLASTIC MANAGEMENT: MONITORING, BIOLOGICAL IMPACT, AND CIRCULAR PERSPECTIVES ROUND TABLE REPORT Giorgia Görner Enrile1|2, Antonietta Santoro3, Federica Scalia4, Stefania D’Angelo5, Annamaria Visco6, Andrea Pace7, Michele Torregrossa8, Dario Scalia9, Alessandro Aglialoro10, Salvatore Campanella10 | 1Siciliamedica.it; 2Ilsicilia.it; 3PI, Plastamination Project, University of Salerno, Italy; 4Human Anatomy, University Kore, Enna, Italy; 5Biochemistry, University Parthenope of Naples, Italy; 6Life Restart Project, University of Messina, Italy; 7Research and Technology Transfer, University of Palermo, Italy; 8Engineering, University of Palermo, Italy; 9Plastic Free Onlus Sicily, Italy; 10Regional Environmental Protection Agency of Sicily, Italy
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027 | Exploring the cooperative effect of osilodrostat and mitotane in 3D spheroid models of adrenocortical carcinoma Fabiola Vaglica1, Laura Tomasello1, Mattia Biondo2, Giuseppe Siragusa2, Giorgio Arnaldi1, Giuseppe Pizzolanti1|3, Valentina Guarnotta1 | 1Dept. of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties PROMISE, University of Palermo; 2Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo; 3ATeN Center, Palermo, Italy.
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073 | Modulation of NLRP3 inflammasome and macrophage polarization by quantum molecular resonance in THP-1 cells Maria Giulia Di Battista1, Osama Elsallabi1, Benedetta Rizza1, Tiziano Lupi1, Alessandro Pozzato2, Paola Lanuti1, Antonia Patruno1 | 1Department of Medicine and Aging Sciences, University “G. d’Annunzio” of Chieti-Pescara, Italy; 2Telea Electronic Engineering Srl, Sandrigo [VI], Italy.
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146 | Preventive effect of intranasal lemon-derived nanovesicles in a high-fat diet rat model of metabolic syndrome: modulation of anxiety-like behavior and survival signalling pathways Andrea Giubilato1, Nicolò Ricciardi1, Valentina Di Liberto1, Miriana Scordino1, Giulia Urone1, Danila Di Majo1, Giuseppe Giglia1|4, Pierangelo Sardo1, Giuseppe Ferraro1, Riccardo Alessandro1|2|3, Stefania Raimondo1|2, Giuditta Gambino1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, University of Palermo, Section of Human Physiology, Biology and Genetics, Palermo, Italy; 2Navhetec srl, Spinoff of the University of Palermo, Palermo, Italy; 3Institute for Biomedical Research and Innovation IRIB, National Research Council CNR, Palermo, Italy; 4Euro Mediterranean Institute of Science and Technology-IEMEST, Palermo, Italy.
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081 | Redox imbalance and ER stress mediate the anti-cancer effects of quinoline-based derivatives in triple-negative breast cancer cells Chiara Occhipinti1, Gabriele La Monica2, Federica Alamia2, Alessia Bono2, Antonino Lauria2, Annamaria Martorana2, Antonella D’Anneo1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, Laboratory of Biochemistry, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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EXPLORING THE NEUROTOXIC POTENTIAL OF LDPE MICROPLASTICS: EVIDENCE IN VITRO AND IN VIVO ASSESSMENT Marilena MARRAUDINO1,2, Elena RICCI1,2, Silvia CHASSEUR1,2, Daniela RASA'1, Riccardo ROLANDO1, Stefano GOTTI1,2, Marina BOIDO1,2 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (TO), Italy; 2Department of Neuroscience ‘Rita Levi Montalcini’, University of Torino, Torino, Italy
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016 | Mechanisms underlying resistance to CDK4/6 inhibitors in aggressive medulloblastoma subtypes Alice Foti1, Fabio Allia1, Marilena Briglia1, Gianpiero Tamburrini2, Roberta Malaguarnera1, Francesco Cecconi2|3, Vittoria Pagliarini2|3, Veronica Marabitti4, Francesca Nazio4, Adriana C.E. Graziano1 | 1University of Enna “Kore”, Enna, Italy; 2Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; 3Università Cattolica del Sacro Cuore, Rome, Italy; 4University of Rome Tor Vergata, Rome, Italy.
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066 | Modulation of oxidative stress and mitochondrial alteration in IL1β-stimulated human astrocytes: effects of extracts from leaves and rhizomes of Posidonia oceanica (L) Delile Giulia Abruscato1, Lucia Sileo2, Giulia Scanavino2, Manuela Mauro1, Francesco Longo1, Vincenzo Arizza1|3, Mirella Vazzana1|3, Claudio Luparello1|3, Ada Maria Tata2 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STeBICeF, University of Palermo, Italy; 2Department of Biology and Biotechnologies Charles Darwin, Sapienza- University of Rome, Italy; 3National Biodiversity Future Center NBFC, Palermo, Italy.
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EFFECTS OF POLYLACTIC ACID-NANOPLASTICS ON THE INTESTINAL BARRIER: IN VITRO ANALYSIS ON HUMAN EPITHELIAL CELLS Maria Gerarda LULLO1, Raffaella D’AURIA1, Marianna MARINO1, Martina LOMBARDI1, Giovanna DELLA PORTA1,2, Erwin Pavel LAMPARELLI1, Rosaria MECCARIELLO3, Andrea VIGGIANO1,2, Antonietta SANTORO1,2 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Fisciano, Salerno, Italy; 2Interdepartmental Observatory for Scientific Health Initiatives in Environmental Legislation and Disease Prevention, SHIELD, University of Salerno, Italy; 3Department of Medical, Motor and Wellness Sciences, University of Naples Parthenope, Naples, Italy
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012 | Anticancer activity of Orobanche crenata leaf extract in human colorectal cancer cell lines Floriana D’Angeli1, Alfio Distefano2, Laura Orlando2, Elisa Gili3, Valentina Di Salvatore4, Simone Ronsisvalle4, Ivana Roberta Romano2, Giuliana Mannino2, Debora Lo Furno2, Giovanni Giurdanella1, Giovanni Li Volti2, Carlo Genovese1 | 1Department of Medicine and Surgery, School of Medicine and Surgery, University of Enna "Kore", Enna, Italy; 2Department of Biomedical and Biotechnological Sciences, University of Catania, Italy; 3Department of Clinical and Experimental Medicine, "Regional Referral Center for Rare Lung Diseases", University, Hospital Policlinico "G. Rodolico-San Marco", University of Catania, Italy; 4Department of Health and Drug Sciences, University of Catania, Italy.
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086 | Kir4.1 channels at the crossroads of oxidative stress and presbycusis: redox imbalance, electrophysiological failure and quercetin-mediated rescue Sara Spinelli1, Alessia Remigante2, Angela Marino1, Rossana Morabito1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina, Italy.
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D-ASPARTATE ALLEVIATES THE TESTICULAR DAMAGE INDUCED BY POLYSTYRENE MICROPLASTICS Sara FALVO1, Giulia GRILLO1, Gabriella CHIEFFI BACCARI1, Alessandra SANTILLO1, Imed MESSAOUDI2, Maria Maddalena DI FIORE1, Alessandra BIASI3, Maria Rosaria AMBRUOSI3, Massimo VENDITTI3 | 1Dept. of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania L. Vanvitelli, Caserta, Italy; 2LR11ES41: Génétique, Biodiversité et Valorisation des Bioresources, Institut Supérieur de Biotechnologie, Université de Monastir, Monastir, Tunisia; 3Dept of Experimental Medicine, University of Campania ‘Luigi Vanvitelli’, Napoli, Italy
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10 | EFFECTS OF POLYLACTIC ACID NANOPLASTICS ON RAT SPERM PARAMETERS Maria Zelinda Romano1, Martina Lombardi2, Massimo Venditti1, Mariagerarda Lullo2, Marianna Marino2, Erwin Pawel Lamparelli2, Giovanna Della Porta2, Antonino Testa3, Andrea Viggiano2, Antonietta Santoro2, Rosara Meccariello4 | 1Department of Experimental Medicine, University of Campania “L Vanvitelli”, Naples Italy; 2Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi, Salerno, Italy; 3Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Caserta, Italy; 4Department of Medical, Human Movement and Well-being Sciences, University of Naples Parthenope, Naples, Italy
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Metabolic effects of 3,5-Diiodo-L-Thyronine
2501Downloads: 485 -
083 | HSV-1 replication and chemokines activation in human monocytes are suppressed by Pistacia vera l. extracts Rosamaria Pennisi1, Marianna Costa1|2, Paola Trischitta1|2, Giuseppina Mandalari1, Maria Teresa Sciortino1. | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy.
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TOXIC EFFECTS OF POLYLACTIC ACID NANOPLASTICS ON IN VITRO MODELS OF ASTROCYTES AND NEURONS Marianna MARINO1, Martina LOMBARDI1-3, Raffaella D’AURIA1, Erwin Pavel LAMPARELLI1, Giovanna DELLA PORTA1,4, Marta Anna SZYCHLINSKA5, Federica SCALIA6, Francesco CAPPELLO6,7, Rosaria MECCARIELLO8, Andrea VIGGIANO1,4, Antonietta SANTORO1,4 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 2Theoreo Srl, Montecorvino Pugliano, SA, Italy; 3European Institute of Metabolomics - Fondazione EIM, Baronissi, SA, Italy; 4Interdepartmental Observatory for Scientific Health Initiatives in Environmental Legislation and Disease Prevention, SHIELD, University of Salerno, Italy; 5Department of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, Italy; 6Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 7Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; 8Department of Physical Sciences and Wellness, University of Naples Parthenope, Italy
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107 | Protective effects of hydroxytyrosol against dichlorodiphenilethylene-induced oxidative injury in liver cells Vincenzo Migliaccio1, Ilaria Di Gregorio1, Martina Coletta1, Giuliana Panico2, Assunta Lombardi2, Lillà Lionetti1 | 1Dept Chemistry and Biology “Adolfo Zambelli”, University of Salerno, Italy; 2Dept Biology, University Federico II, Napoli, Italy.
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PRELIMINARY RESULTS ON MICROPLASTIC AND NANOPLASTIC IMPACT IN VIRUS AND BACTERIAL REPLICATION Nicoletta CAPUANO1,2, Alessia GIANNATTASIO3, Noemi CAFA’1,2, Anna BARBATO1,2, Mariarosa SCOGNAMIGLIO4, Vincenzo BELGIORNO5, Luca RINALDI6, Veronica FOLLIERO1,2, Antonio BUONERBA3, Gianluigi FRANCI1,2 | 1Dipartimento di Medicina, Chirurgia e Odontoiatria, Scuola Medica Salernitana, Università degli Studi di Salerno, Baronissi (SA), Italia; 2UOS di Microbiologia e Virologia, AOU San Giovanni di Dio e Ruggi D’Aragona, Salerno, Italia; 3Dipartimento di Chimica e Biologia, Università degli Studi di Salerno, Fisciano (SA), Italia; 4Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA), Italia; 5Dipartimento di Ingegneria Civile, Università degli Studi di Salerno, Fisciano (SA), Italia; 6Dipartimento di Medicina e Scienze della Salute, Università degli Studi del Molise, Italy
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070 | Role of bioactive extracts obtained from marine sources and agri-food industry by-products in ETosis modulation Federica Bellistrì1, Giulia Abruscato1, Manuela Perlotti1, Alessia Lo Muzzo1, Claudio Gargano1, Francesco Longo1, Manuela Mauro1, Roberto Chiarelli1, Vincenzo Arizza1|3, Claudio Luparello1|3, Gianluca Sarà2|3, Mirella Vazzana1|3 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Earth and Marine Sciences, Palermo, Italy; 3National Biodiversity Future Center, Palermo, Italy.
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142 | Drug repositioning reveals novel therapeutic candidates for spinal muscular atrophy Marina Boido1, Daniela Maria Rasà1, Serena Stanga1, Ersilia Nicorvo1, Pamela Santonicola2, Nadia Mazzarella3, Antonella Camera2, Roberto Iacomino2, Ilenia Matino2, Silvia Chasseur1, Giuseppina Zampi2, Piera Smeriglio4, Elia Di Schiavi2, Alessandro Vercelli1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy; 2Institute of Biosciences and BioResources IBBR, National Research Council CNR, Naples, Italy; 3Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" IGB-ABT, National Research Council CNR, Naples, Italy; 4Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
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080 | Monocytes succumb to protect head and neck cancer cells from plasma-treated water solutions cytotoxicity Giuseppe Natali1, Anna Martina Battaglia2, Emanuele Giorgio2, Lavinia Petriaggi2, Alessandro Antonelli3, Cristiana Galeano2, Amerigo Giudice3, Eloisa Sardella4, Vittoria Perrotti5, Flavia Biamonte2 | 1Department of Health Sciences, Magna Graecia University of Catanzaro, Italy; 2Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Italy; 3Department of Health Science, School of Dentistry, Magna Graecia University of Catanzaro, Italy; 4CNR-Istituto di Nanotecnologia CNR-NANOTEC UoS Bari, c/o Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, Italy; 5Department of Innovative Technologies in Medicine & Dentistry, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy.
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The role of selenium in autoimmune thyroiditis
1735Downloads: 464 -
182 | Preliminary data on clinical assessment, blood biochemistry analysis, and infrared thermography in dairy cows affected by foot diseases Maria Rizzo1, Nicolò Parisi1, Andrea Spadaro1, Esterina Fazio1, Enrico Fiore2, Giorgia Taio2, Giuseppe Piccione1, Francesca Arfuso1, Filippo Spadola1 | 1Department of Veterinary Sciences, University of Messina, Polo University Annunziata, Messina, Italy; 2Department of Animal Medicine, Productions and Health MAPS, University of Padua, Legnaro, Italy;.
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155 | Mitochondrial dynamics and therapeutic insights in spinal muscular atrophy: effects of MFN2 boosting in motoneurons and human fibroblasts Francesco Paolo Zummo1, Serena Stanga1, Letizia Paladino2, Maria Beltran3, Francesco Fedeli4, Maria Rosa Soler3, Fabio Bucchieri5, Marina Boido1 | 1Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy; 2E-Campus University, Palermo, Italy; 3Neuronal Signaling Unit, Experimental Medicine Department, University of Lleida-IRBLleida, Lleida, Spain; 4University of Pavia, Italy; 5Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy.
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181 | Exploring boron neutron capture therapy effects on healthy skin: from cells to tissues Stefania Ricci1|2|3, Silva Bortolussi3|4, Ricardo Luis Ramos3|4, Ian Postuma3, Daniele Dondi3|5, Cinzia Ferrari3|7, Laura Cansolino3|7, Tea Maverna2, Federica Riva2|3 | 1Dept of Internal Medicine and Medical Therapy, University of Pavia, Italy; 2Dept of Experimental Medicine, Histology and Embryology Unit, University of Pavia, Italy; 3National Institute of Nuclear Physics INFN, Unit of Pavia, Italy; 4Dept of Physics, University of Pavia, Italy; 5Dept of Chemistry, University of Pavia, Italy; 6Dept of Molecular Medicine, Human Physiology Unit, University of Pavia, Italy; 7Laboratory of Experimental Surgery, Department of Clinical-Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Italy.
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121 | Probiotics effect on brain-gut axis mediated by nanovescicles Alessandro Lo Giudice1, Giuseppa D’Amico1, Melania Ionelia Gratie1, Letizia Paladino2, Giusy Vultaggio1, Adelaide Carista1, Francesco Cappello1, Vita Di Stefano3, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy; 3Department of Biological, Chemical, and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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076 | Iron-driven redox dysregulation fuels psoriatic signaling in CARD14 e138a mutant keratinocytes Cristiana Galeano1, Anna Martina Battaglia1, Emanuele Giorgio1, Lavinia Petriaggi1, Giuseppe Natali2, Flavia Biamonte1 | 1Laboratory of Biochemistry and Cell Biology, Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Italy; 2Department of Life Science, Magna Graecia University of Catanzaro, Italy.
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Adipokines in obesity and metabolic diseases
1058Downloads: 552