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070 | Role of bioactive extracts obtained from marine sources and agri-food industry by-products in ETosis modulation Federica Bellistrì1, Giulia Abruscato1, Manuela Perlotti1, Alessia Lo Muzzo1, Claudio Gargano1, Francesco Longo1, Manuela Mauro1, Roberto Chiarelli1, Vincenzo Arizza1|3, Claudio Luparello1|3, Gianluca Sarà2|3, Mirella Vazzana1|3 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Earth and Marine Sciences, Palermo, Italy; 3National Biodiversity Future Center, Palermo, Italy.
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162 | Functional and health-promoting properties of EVOO from Sicilian olive cultivars: focus on oxidative stress and inflammation Mariateresa Cristani1, Ali Mert Yetisgin2, Giovanni Bartolomeo3, Nicola Cicero3|4, Rosaria Costa3, Nicola Micale1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2İnönü University, Faculty of Pharmacy, Kampüs, Battalgazi/Malatya, Türkiye; 3Department of Biomedical, Dental, Morphological and Functional Images Sciences BIOMORF, University of Messina, Messina, Italy; 4Science4Life srl, start-up of the University of Messina, Messina, Italy.
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EVALUATING ENDOCRINE AND OXIDATIVE EFFECTS OF POLYLACTIC ACID NANOPLASTICS (PLA-NPs) ON BREAST CELL MODELS Maria Denise AMICO1, Antonietta SANTORO2, Erwin Pavel LAMPARELLI2, Giovanna DELLA PORTA2, Magdalena GORSKA-PONIKOWSKA3,4,5, Francesca RAPPA1,5, Fabio BUCCHIERI1, Francesco CAPPELLO1,5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medical Chemistry, Medical University of Gdansk, Poland; 4Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Germany; 5Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
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103 | Valorization of olive mill wastewaters for the recovery of polyphenols with reducing, radical scavenging and anti-inflammatory activities Francesco Longo1, Luisa Tesoriere1, Claudio Luparello1, Ignazio Restivo1, Federica Bellistrì1, Serena Indelicato1, David Bongiorno1, Rosi De Luca1, Giulia Abruscato1, Antonio Fabbrizio2, Salvatore Terrani3, Mirella Vazzana1, Vincenzo Arizza1, Manuela Mauro1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences DiSTA, University e Campus, Novedrate [CIO], Italy; 3The Wave Innovation Group, Verona, Italy.
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039 | Age and growth of the mesopelagic fish Electrona risso (myctophidae) from the Strait of Messina (central Mediterranean sea) Calogero Fontana1, Alice Vaccaro2, Francesco Longo1, Danilo Malara3, Emanuela Fanelli2|4, Pietro Battaglia1|4 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2Università Politecnica delle Marche UNIVPM, Dipartimento di Scienze della Vita e dell’Ambiente, Ancona, Italy; 3Northern Territory Government of Australia, Department of Agriculture and Fisheries, Fisheries Division, Berrimah, NT, Australia; 4National Biodiversity Future Center, Palermo, Italy.
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MICROPLASTIC INGESTION BY MARINE FISH FROM THE CENTRAL TYRRHENIAN SEA: TOWARD THE IDENTIFICATION OF REGIONAL BIOINDICATORS Tommaso VALENTE1, Paolo TOMASSETTI1, Laura CIARALLI1,2, Eleonora MONFARDINI1,3, Cecilia SILVESTRI1, Marco MATIDDI1 | 1ISPRA, Italian Institute for Environmental Protection and Research, CN-LAB/BIO; 2Department of Biology, University of Naples Federico II; 3Department of Environmental Biology, La Sapienza University of Rome, Italy
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UNTARGETED METABOLOMICS REVEALS GONADAL METABOLIC DISRUPTION IN MYTILUS GALLOPROVINCIALIS EXPOSED TO CADMIUM AND MICROPLASTICS Vera ABENANTE1,2, Andrea INGENITO1,2, Alessio TROTTA1,2, Giulio SANTANIELLO3, Gennaro LETTIERI3 , Marina PISCOPO3, Jacopo TROISI1,2,4 | 1Theoreo S.r.l., University of Salerno; 2European Institute of Metabolomics - Fondazione EIM, Baronissi (SA); 3Department of Biology, University of Naples Federico II, Naples; 4Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy
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050 | Proliferative kidney disease: new insights for Piedmont region; correlation between clinical signs and proliferative kidney disease positivity in rainbow trout Giorgia Zicarelli1, Annalisa Cotugno1, Sara Glorio Patrucco1, Silvia Colussi1|2, Giulia Milanese1, Giulia Stilo1, Martina Gini1, Pier Luigi Acutis1, Caterina Faggio3|4, Giuseppe Esposito1, Paolo Pastorino1, Marino Prearo1 | 1Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Turin, Italy; 2Department of Animal, Nutritional and Food Sciences, Università Cattolica del Sacro Cuore, Piacenza, Italy; 3Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 4Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Napoli, Italy.
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POLYSTYRENE NANOPARTICLES IN ZEBRAFISH: THEIR ROLE IN OCULAR STRESS AND LIPID METABOLIC IMBALANCE V. IEZZI1, F. PERRELLA2, S. ZUGARO1, R. M. FERRI1, A. IANNETTA3, L. SULCANESE3, T. SILVESTRINI3,4, M. PERUGINI3, E. BENEDETTI1, C. FERRANTE5 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila; 2Department of Physical and Chemical Sciences University of L’Aquila; 3Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo; 4Advanced Study “Theoretical and Applied Neuroscience” Preclinical, clinical and Translational neuroscience, University of Camerino, Italy; 5CNR-SPIN, c/o Department of Physical and Chemical Sciences University of L’Aquila, Italy
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102 | Polylactic acid nanoparticles as metabolically active entities: a metabolomics and fluxomics perspective Martina Lombardi1|2|3, Vera Abenante2|3, Alessio Trotta2|3, Erwin Pavel Lamparelli1, Federica Montella1, Giovanna Della Porta1, Andrea Viggiano1, Jacopo Troisi1|2|3|4, Antonietta Santoro1 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 2Theoreo Srl, Montecorvino Pugliano, Salerno, Italy; 3European Institute of Metabolomics - Fondazione EIM, Baronissi, Salerno, Italy; 4Department of Chemistry and Biology, “A Zambelli”, University of Salerno, Fisciano [SA], Italy.
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091 | Increased vulnerability to experimental colitis following chronic low-dose exposure to Sicilian environmental contaminants Noemi Aloi1|2, Paolo Colombo2, Valeria Longo2, Rosa Serio1, Maria Grazia Zizzo1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, Università di Palermo, Italy; 2Institute for Biomedical Research and Innovation, National Research Council of Italy IRIB-CNR, Palermo, Italy.
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035 | Shkodra lake – Drini river basin and buna in UNESCO Transboundary Biosphere Reserve: values to be protected and used in a sustainable way Aurora Dibra, Neira Medja, Irida Zmijanej, Gjergj Shegaj | University of Shkodra “Luigj Gurakuqi” Faculty of Natural Sciences, Tirana, Albania.
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126 | Vertical stratification shapes microbial community assembly in the meromictic Lake Faro water column Erika Arcadi1, Carmen Rizzo2|3, Rosario Calogero1, Marilena Sanfilippo1, Francesco Fabiano4|5, Vittoria Dias2|6, Teresa Romeo5|7|8 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 3Institute of Polar Sciences, National Research Council CNR-ISP, Messina, Italy; 4Department of Earth and Marine Sciences, University of Palermo, Italy; 5National Biodiversity Future Centre NBFC, Italy; 6Earth and Environmental Science Department, University of Milano Bicocca, Milano, Italy; 7Department of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Milazzo [ME], Italy; 8National Institute for Environmental Protection and Research, Milazzo [ME], Italy.
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SWIMMING IN PLASTAMINATION: POLY-LACTIC ACID NANOPLASTICS AND SPERM FUNCTIONS Alberto CONTRI1, Massimo VENDITTI2, Alessia GLORIA1, Marianna MARINO3, Erwin Pavel LAMPARELLI3, Giovanna DELLA PORTA3, Antonietta SANTORO3, Rosaria MECCARIELLO4 | 1Department of Veterinary Medicine, University of Teramo; 2Department of Experimental Medicine, University of Campania “L. Vanvitelli”, Naples; 3Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi (SA); 4Department of Medical, Human Movement and Well-being Sciences, Parthenope University of Naples, Italy
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049 | CMIT as an emerging contaminant: physiological and biochemical effects in Mytilus galloprovincialis Giuseppe Stracuzzi1, Federica Impellitteri1, Maria Giovanna Rizzo1, Monia Perugini2, Marika Cordaro3, Kateryna Yunko4, Oksana Stoliar4, Caterina Faggio1|5 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Feed and Food Scienxes, Teramo Univesity, Teramo, Italy; 3Department of Biomedical, Dental and Morphological and Functional Imaging University of Messina, Messina, Italy; 4Ternopil Volodymyr Hnatiuk National Pedagogical University, Ternopil, Ukraine; 5Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.
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146 | Preventive effect of intranasal lemon-derived nanovesicles in a high-fat diet rat model of metabolic syndrome: modulation of anxiety-like behavior and survival signalling pathways Andrea Giubilato1, Nicolò Ricciardi1, Valentina Di Liberto1, Miriana Scordino1, Giulia Urone1, Danila Di Majo1, Giuseppe Giglia1|4, Pierangelo Sardo1, Giuseppe Ferraro1, Riccardo Alessandro1|2|3, Stefania Raimondo1|2, Giuditta Gambino1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, University of Palermo, Section of Human Physiology, Biology and Genetics, Palermo, Italy; 2Navhetec srl, Spinoff of the University of Palermo, Palermo, Italy; 3Institute for Biomedical Research and Innovation IRIB, National Research Council CNR, Palermo, Italy; 4Euro Mediterranean Institute of Science and Technology-IEMEST, Palermo, Italy.
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CELL SPECIFIC METABOLOMIC AND FLUXOMIC RESPONSES TO POLYLACTIC ACID NANOPLASTICS EXPOSURE IN HUMAN INTESTINAL CELLS Martina LOMBARDI1,2,3, Raffaella D’AURIA1, Marianna MARINO1, Mariagerarda LULLO1, Erwin Pavel LAMPARELLI1, Federica MONTELLA1, Giovanna DELLA PORTA1,4, Andrea VIGGIANO1, Jacopo TROISI1,2,3,5, Antonietta SANTORO1,4 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno; 2Theoreo Srl, Montecorvino Pugliano (SA); 3European Institute of Metabolomics - Fondazione EIM, Baronissi (SA); 4Interdepartmental Observatory for Scientific Health Initiatives in Environmental Legislation and Disease Prevention, SHIELD, University of Salerno; 5Department of Chemistry and Biology, “A. Zambelli”, University of Salerno, Fisciano (SA), Italy
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100 | Tracking polystyrene nanoplastics by raman microscopy reveals intestinal and retinal toxicity Valentina Iezzi1, Roberta Maria Ferri1, Annamaria Iannetta2, Ludovica Sulcanese2, Tommaso Silvestrini2, Vanessa D’Altilia2, Giovanni Angelozzi2, Federico Perrella3, Carino Ferrante4, Giulia Fioravanti3, Monia Perugini2, Elisabetta Benedetti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Italy; 3Department of Physical and Chemical Sciences University of L’Aquila, Italy; 4CNR-SPIN, c/o department of Physical and Chemical Sciences University of L’Aquila, Italy.
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TINY PLASTICS, BIG PRESSURE: NANOPLASTIC ACCUMULATION IN BENTHIC MEIOFAUNA Adele COCOZZA DI MONTANARA1,2,3,4, Carola MURANO2,5, Marco UTTIERI1,2, Roberto SANDULLI3,4, Teresa ROMEO2,6, Antonio TERLIZZI4,7 | 1Department of Integrate Marine Ecology, Stazione Zoologica Anton Dohrn, Naples, Italy; 2National Biodiversity Future Center (NBFC), Palermo, Italy; 3Dipartimento di Scienze e Tecnologie, Università di Napoli Parthenope, Naples, Italy; 4Consorzio Nazionale Interuniversitario per le Scienze del Mare (CoNISMa), Rome, Italy; 5Department of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, Brindisi Marine Centre, Brindisi, Italy; 6Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Department of Biology and Evolution of Marine Organisms (BEOM), Milazzo (ME), Italy; 7Department of Life Sciences, University of Trieste, Trieste, Italy
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122 | Tangential flow filtration enables high-yield isolation and stable characterization of grape-derived extracellular vesicles for therapeutic application Sabino Porro1|2, Tamer Esmail1|2, Francesca D’Ascanio1|2|3, Giulia Colasante1|2, Arianna Aquilini-Mummolo,1|2, Luana D’Onofrio1|2, Mariagiulia Filoso1|2, Ayesha Younas1|2, Isabel Maria Vallejo Bermudez4|5, Camilla Cichella1|2, Michela Battistelli6, Anna Piro7, Serena Veschi7, Serena Pilato7, Antonella Fontana7, Alessandro Cama7, Angelo Cichelli8, Paola Lanuti1|2, Federica Flamminii9 | 1Department of Medicine and Aging Sciences, University “G d’Annunzio” of Chieti-Pescara, Italy; 2Center for Advanced Studies and Technology CAST; 3Molecular Immunology Group CTS208 Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy; 4Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; 5Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain; 6Department of Biomolecular Sciences DISB University of Urbino Carlo Bo, Italy; 7Department of Pharmacy, University “G d’Annunzio” of Chieti-Pescara, Italy; 8Department of Innovative Technologies in Medicine & Dentistry, University “G d’Annunzio” of Chieti-Pescara, Italy; 9Department of Promotion of Human Sciences and Quality of Life, San Raffaele Telematic University, Rome, Italy.
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NANOPLASTICS AND IMMUNITY: INVESTIGATING THE EXTRACELLULAR MATRIX’S INFLUENCE ON MACROPHAGE INTERACTION WITH POLYSTYRENE NANOPARTICLES Marianna ROCA1, Naym BLAL1, Zeynep RENKLER2, Vincenzo GUARINO2, Antonia DI MOLA1, Antonio MASSA1, Ilaria DE MARTINO3, Velia SICILIANO3, Daniela GUARNIERI1 | 1Department of Chemistry and Biology, “Adolfo Zambelli”, University of Salerno; 2Institute of Polymers, Composites and Biomaterials, National Research Council of Italy; 3Synthetic and Systems Biology for Biomedicine Lab, Istituto Italiano di Tecnologia, Naples, Italy
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