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Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

Editors-in-Chief: Gian Luigi Mariottini - Antonella Marino Gammazza, Italy | eISSN 2284-0230 - pISSN 1826-8838

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  • Unleashing the potential of millets: a comprehensive review of its nutritional, therapeutic, and genomic attributes

    Biju Vadakkemukadiyil Chellappan, Rajendran Peramaiyan
    07-05-2024
    https://doi.org/10.4081/jbr.2024.12131
    1785
    Downloads: 1159
  • 072 | A standardized onion peel-derived bioactive ingredient attenuates palmitate-induced steatosis and oxidative stress in HepG2 cells Ilaria Di Gregorio1|2, Vincenzo Migliaccio2, Maria D’Elia1|3|4, Rita Celano1|3, Anna Lisa Piccinelli1|3, Luca Rastrelli1|3, Lillà Lionetti2|3 | 1Dept Pharmacy, University of Salerno, Salerno, Italy; 2Dept Chemistry and Biology “A Zambelli”, University of Salerno, Italy; 3National Biodiversity Future Center NBFC, Palermo, Italy; 4Dept Earth and Marine Sciences, University of Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15324
    100
  • 151 | Dysregulation of the lung-brain axis induced by CMIT/MIT: oxidative stress and junctional protein impairment lead to α-synuclein accumulation and dopaminergic neurotoxicity Nicla Tranchida1, Rosanna Di Paola2, Marika Cordaro3 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Italy; 3Department of Biomedical, Dental and Morphological and Functional Imaging University of Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15403
    103
  • Therapeutic potential of Withania somnifera (Ashwagandha): a comprehensive review of its phytochemical, pharmacological, and clinical applications

    Martina Martorana, Anastasia Valentina Liga, Fabio Venturella
    12-12-2025
    https://doi.org/10.4081/jbr.2025.13901
    2631
    Downloads: 777
  • 090 | Activation of Sirtuin-1 by Cipollotto Nocerino leaf extract protects HepG2 cells from lipotoxicity Vincenzo Vestuto1, Maria Rosaria Miranda1, Giovanna Aquino2, Tania Ciaglia1, Rodolfo Maria Abbate1, Giuseppina Amodio3, Manuela Giovanna Basilicata4, Mario Felice Tecce1, Luca Rastrelli1, Pietro Campiglia1, Michele Manfra5, Giacomo Pepe1 | 1Department of Pharmacy, University of Salerno, Italy; 2AREA Science Park, Laboratorio di Multi-omica Area Sud LAAS, Baronissi [SA], Italy; 3Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi [SA], Italy; 4Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy; 5Department of Science, University of Basilicata, Potenza, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15342
    137
  • Effect of cadmium on anion exchange capability through Band 3 protein in human erythrocytes

    Rossana Morabito, Alessia Remigante, Benedetta Arcuri, Angela Marino, Marco Giammanco, Giuseppina La Spada, Angela Marino
    15-05-2018
    https://doi.org/10.4081/jbr.2018.7203
    1312
    Downloads: 676
  • 09 | POLY(LACTIC ACID) PLASTICS CONTAMINATION (PLASTINATION): ORGAN INJURIES AND UNDERLINING MOLECULAR MECHANISMS: EVIDENCE FROM IN VIVO ZEBRAFISH MODEL Marta A. Szychlinska1, Federica Scalia2, Martina Di Marco3, Giusy Vultaggio3, Maria Denise Amico3, Fabiano Capparucci4, Carmelo Iaria4, Marianna Marino5, Erwin Pavel Lamparelli5, Giovanna Della Porta5, Francesca Rappa3, Antonella Marino Gammazza3, Rosario Barone3, Antonino Testa6, Rosaria Meccariello7, Antonietta Santoro5, Francesco Cappello3 | 1Department of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, Italy; 2Department of Medicine and Surgery - Kore University of Enna, Italy; 3Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Italy; 4Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Italy; 5Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 6Department of Biological and Pharmaceutical Environmental Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Caserta, Italy; 7Department of Movement and Wellness Sciences, Parthenope University of Naples, Italy

    Società Italiana di Biologia Sperimentale
    20-04-2026
    https://doi.org/10.4081/jbr.2026.15578
    218
    Downloads: 75
  • 049 | CMIT as an emerging contaminant: physiological and biochemical effects in Mytilus galloprovincialis Giuseppe Stracuzzi1, Federica Impellitteri1, Maria Giovanna Rizzo1, Monia Perugini2, Marika Cordaro3, Kateryna Yunko4, Oksana Stoliar4, Caterina Faggio1|5 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Feed and Food Scienxes, Teramo Univesity, Teramo, Italy; 3Department of Biomedical, Dental and Morphological and Functional Imaging University of Messina, Messina, Italy; 4Ternopil Volodymyr Hnatiuk National Pedagogical University, Ternopil, Ukraine; 5Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15301
    112
  • Biochemical adaptations in middle-distance runners: an assessment of blood and anthropometric parameters

    Danila Di Majo, Gabriella Schiera, Valentina Contrò, Elena Joana Armeli, Marcello Giaccone, Marco Giammanco, Marcello Traina, Antonio Palma, Patrizia Proia
    09-12-2014
    https://doi.org/10.4081/jbr.2014.4713
    2112
    Downloads: 1015
  • 068 | In vitro modulation of inflammatory mediators by eggplant peel extracts from two cultivar Alessandra Armeli, Desirèe Bonfiglio, Serena Munaò, Giovanna Calabrese | Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15320
    102
  • 146 | Preventive effect of intranasal lemon-derived nanovesicles in a high-fat diet rat model of metabolic syndrome: modulation of anxiety-like behavior and survival signalling pathways Andrea Giubilato1, Nicolò Ricciardi1, Valentina Di Liberto1, Miriana Scordino1, Giulia Urone1, Danila Di Majo1, Giuseppe Giglia1|4, Pierangelo Sardo1, Giuseppe Ferraro1, Riccardo Alessandro1|2|3, Stefania Raimondo1|2, Giuditta Gambino1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, University of Palermo, Section of Human Physiology, Biology and Genetics, Palermo, Italy; 2Navhetec srl, Spinoff of the University of Palermo, Palermo, Italy; 3Institute for Biomedical Research and Innovation IRIB, National Research Council CNR, Palermo, Italy; 4Euro Mediterranean Institute of Science and Technology-IEMEST, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15398
    156
  • 185 | From mycelium to medicine: cytotoxic effects of Ganoderma adspersum extracts in renal cancer cells Maria Noemi Sgobba1, Nikola Schlosserova1|2, Biagia Musio3, Federica Mastropirro1, Antonio Radesco4, Maria Favia5, Simona Marianna Sanzani4, Stefano Todisco3, Mariateresa Volpicella1, Anna De Grassi1, Vito Gallo3, Elena Ciani1, Ciro Leonardo Pierri6, Jakub Treml7, Lorenzo Guerra1 | 1Department of Biosciences, Biotechnologies and Environment, University of Bari, Italy; 2Department of Chemistry and Biochemistry, Faculty of AgriSciences, Mendel University in Brno, Czech Republic; 3Department of Civil, Environmental, Land, Building Engineering and Chemistry DICATECh, Polytechnic University of Bari, Italy; 4Department of Soil, Plant and Food Sciences, University of Bari, Italy; 5Department of Translational Biomedicine and Neurosciences DiBraiN, University of Bari, Italy; 6Department of Pharmacy – Pharmaceutical Sciences, University of Bari, Italy; 7Department of Molecular Pharmacy, Faculty of Pharmacy, Masaryk University, Brno, Czech Republic.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15437
    105
  • Xenopus laevis embryos: biochemical evaluations in simulated microgravity condition

    B. Berra, G. Montorfano, M. Negroni, S. Zava, A.M. Rizzo
    31-01-2009
    https://doi.org/10.4081/jbr.2009.4727
    776
    Downloads: 616
  • 065 | Phytochemical profile, oxidative response and antimicrobial activity of Scutellaria lateriflora extract against Staphylococcus aureus Dionysia Amanatidou1, Ioannis Tsamesidis1|2, Stylaini Axipolitou2, Nektaria Grammatika2, Antonella Pantaleo3, Eleana Kontonasaki2, Phaedra Eleftheriou1 | 1Department of Biomedical Sciences, International Hellenic University, Thessaloniki, Greece; 2Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece; 3Department of Biomedical Science, University of Sassari, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15317
    89
  • 124 | Immunomodulatory effects of extracellular vesicles from invertebrate species on human cells Kristian Riolo1, Francesco Di Pietro1, Sabrina Oliva1, Claudia Mosca1, Valeria Stefanizzi1, Giovanna Montana2, Annalisa Pinsino2, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15376
    144
  • EVALUATING ENDOCRINE AND OXIDATIVE EFFECTS OF POLYLACTIC ACID NANOPLASTICS (PLA-NPs) ON BREAST CELL MODELS Maria Denise AMICO1, Antonietta SANTORO2, Erwin Pavel LAMPARELLI2, Giovanna DELLA PORTA2, Magdalena GORSKA-PONIKOWSKA3,4,5, Francesca RAPPA1,5, Fabio BUCCHIERI1, Francesco CAPPELLO1,5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medical Chemistry, Medical University of Gdansk, Poland; 4Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Germany; 5Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14556
    253
  • 081 | Redox imbalance and ER stress mediate the anti-cancer effects of quinoline-based derivatives in triple-negative breast cancer cells Chiara Occhipinti1, Gabriele La Monica2, Federica Alamia2, Alessia Bono2, Antonino Lauria2, Annamaria Martorana2, Antonella D’Anneo1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, Laboratory of Biochemistry, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15333
    103
  • 167 | The importance of personalized oxygen-ozone dosing in systemic therapy: algorithmic solutions for regenerative medicine Antonio Galoforo1, Paolo Bonivento2 | 1Tavolo Tecnico “Salute ed Ambiente”, Intergruppo parlamentare “One Health”, Camera dei Deputati, Roma, Italy; 2RING - ODR Research Innovation Networking Generation, Organismo di Ricerca, Milano, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15419
    122
  • Genetic variation in GSTP1 and TBXA2R genes: influence of Badoush cement factory pollutant

    Dema Mohammed Sabah, Mohammad Ibrahim Khalil
    21-11-2024
    https://doi.org/10.4081/jbr.2024.12892
    795
    Downloads: 398
  • 101 | Physiological and cellular responses of the Mediterranean mussel to antifouling biocides 2-n-octyl-4-isothiazolin-3-one and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one, alone and in mixture Federica Impellitteri1, Maria Giovanna Rizzo1, Giuseppe Piccione2, Paolo Pastorino3, Cristiana Roberta Multisanti2, Caterina Faggio1|4 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Messina, Italy; 3Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Torino, Italy; 4Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15353
    92
  • 123 | Characterization of extracellular vesicles from the insect Hermetia illucens, a potential source of bioactive molecules Sharon Catrin Raimondi1, Kristian Riolo1, Domenico Savastano2, Sabrina Oliva1, Jessica Maria Abbate1, Antonio Leonardi1, Alessia Irrera3, Annalisa Pinsino4, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Progetto Hermetia, Gioia Tauro, Reggio Calabria, Italy; 3CNR IMM sede di Messina, Messina, Italy; 4Institute of Translational Pharmacology IFT National Research Council CNR, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15375
    135
  • 078 | Stress-driven Dhurrin accumulation in sorghum revealed by physiological and biochemical markers Alessio Giannilivigni1, Manuela Giraldo-Acosta2, Flavia Girolami3, Stefano Giantin4, Luca Carisio4, Carlo Nebbia3, Marino Bañón Arnao2, Alberico Franzin4, Giuseppe Mannino1. | 1Department of Life Sciences and Systems Biology, Plant Physiology Unit, University of Turin, Italy; 2Department of Plant Biology Plant Physiology, University of Murcia, Spain; 3Department of Veterinary Sciences, University of Turin, Grugliasco [TO], Italy; 4Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta IZSPLV, Turin, Italy; 5Green Has Italia Spa, Plant Physiology Unit, Canale [CN], Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15330
    103
  • Antitumoral activity of curcumin: an adjuvant therapeutic strategy

    Giovanni Tomasello, Marco Giammanco, Margherita Mazzola, Provvidenza Damiani, William Ra’, Paola Giammanco, Francesca Rappa, Alessandro Pitruzzella, Dario Saguto, Benedetto Di Trapani, Giovanni Taverna, Mike Carini, Antonio Ciulla, Francesco Carini
    21-01-2021
    https://doi.org/10.4081/jbr.2020.8252
    871
    Downloads: 506
  • 099 | Mechanistic insights into the ecotoxicity of bisphenol analogues and their mixtures in marine mussels: oxidative stress and neuro-immune responses Antonella Iaconis1, Marika Cordaro2, Davide Di Paola1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 2Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina,, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15351
    96
  • Grape seed oil protects against phenylhydrazine-induced hemolysis in rats

    Reema Turkistani
    21-01-2026
    https://doi.org/10.4081/jbr.2026.14262
    567
    Downloads: 212
  • 062 | Enriched bioplastics with natural compounds as innovative hemocompatible biomaterials targeting red blood cells Stefano Putaggio, Annamaria Russo, Giuseppe Tancredi Patanè, Claudia Gravagno, Antonella Calderaro, Davide Barreca, Silvana Ficarra, Ester Tellone | Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15314
    103
  • 110 | Integrative ultrastructural and molecular evidence of ferroptosis in lead-exposed zebrafish liver Ilaria Olivito, Abdalmoiz I.m. Ahmed, Federica Talarico, Marcello Mezzasalma, Elvira Brunelli | Department of Biology, Ecology and Earth Sciences DiBEST, University of Calabria, Rende [CS], Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15362
    97
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Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

is the official journal of the Società Italiana di Biologia Sperimentale and it is published online by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

pISSN: 1826-8838
eISSN: 2284-0230

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