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08 | Combination therapy targeting HDAC8 and SIRT1 improves muscle integrity in a Duchenne muscular dystrophy zebrafish model Sabrina Carbone1, A. Brix1, L. Lociuro1, O. Gjana1, L. Belleri2, M. Schiavone3, A. Marozzi1, F. Del Bene2, C. De Palma1, A. Pezzotta1, A. Pistocchi1 | 1Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy; 2Sorbonne Université, INSERM U968, CNRS UMR 7210, Institut de la Vision, Paris, France; 3Department of Molecular and translational medicine, Università degli Studi di Brescia, Brescia, Italy.
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Abstract 069 | Exercise oncology and biomarkers: how skeletal muscle interacts with inflammation and immunity Elena Barbieri 1, Giosuè Annibalini 1, Mauro De Santi 1, Giulia Baldelli 1, Veronica Gentilini 1, Francesco Lucertini 1, Valentina Natalucci 1, Marta Imperio 1, Seyedehmahboobeh Mosavi 1, Roberta Saltarelli 1, Fabio Ferrini 1, Matteo Bocconcelli 1, Davide Sisti 1, Simone Barocci 2, Vincenzo Catalano 1, Rita Emili 1 | 1Department of Biomolecular Sciences, University of Urbino, Italy; 2Ospedale Santa Maria della Misericordia, AST Pesaro Urbino, Italy; 3Department of Medicine and Surgery, Section of Hygiene and Public Health, University of Perugia, Perugia, Italy.
121Downloads: 69 -
23 | Preclinical evaluation of 3s-HMGB1 as a therapeutic strategy for Duchenne muscular dystrophy Federica Esposito1, E. Sbolli1, S. Curtarello1, E. Ruggieri1|2, M. Patrone1|2, M. Rodrigues3, V. Taglietti3, F. Relaix3, E. Vénéreau1|2 | 1Unit, Division of Genetics and Cellular Biology, IRCCS Ospedale San Raffaele, Milan, Italy; 2University Vita-Salute San Raffaele, Milan, Italy; 3Univ Paris-Est Créteil, INSERM, U955 IMRB, Créteil, France.
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22 | Subcutaneous injection of microencapsulated Sertoli cells is more efficacious than deflazacort treatment in mdx mice Sara Chiappalupi1|2, G. Gentili1|2, L. Salvadori2|3, I. Arato1, F. Mancuso1, M. Paiella1|2, F. Riuzzi1|2, R. Calafiore1, G. Luca1, G. Sorci1|2 | 1Department of Medicine and Surgery, University of Perugia, Italy; 2Interuniversity Institute of Myology (IIM), Perugia, Italy; 3Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy. | S. Chiappalupi and G. Sorci shared Senior authorship; S. Chiappalupi and G. Gentili contributed equally.
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Abstract 025 | Proteomic profiling of the biofluid marker signature of dystrophinopathies Kay Ohlendieck 1|2, Dieter Swandulla 3, Paul Dowling 1|2 | 1Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland; 2Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland; 3Institute of Physiology, Faculty of Medicine, University of Bonn, Bonn, Germany.
110Downloads: 39 -
10 | Human myogenic progenitor and 3D bioprinting for volumetric muscle loss recovery in swine model Rebecca Deodati, F. De Paolis, E. Guarnaccia, B. Corci, S. Bernardini, M. Costantini, C. Fuoco, C. Gargioli | Dept. of Biology, University of Tor Vergata, Rome, Italy.
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41 | SRT2104 improves muscle and cognitive outcomes and has the potential to enhance μDys gene therapy in Duchenne muscular dystrophy Laura Lociuro1, A. Arcari2, O. Gjana1, G. Scolari1, S.R. Casati1|2, S. Zecchini2, M. Giovarelli2, C. Perrotta2, C. De Palma1 | 1Department of Medical Biotechnology and Translational Medicine (BioMeTra), Università degli Studi di Milano, Segrate (MI), Italy; 2Department of Biomedical and Clinical Sciences "Luigi Sacco" (DIBIC), Università degli Studi di Milano, Italy.
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18 | Double-edge sword of ketogenic diet: hepatic improvement at the expense of musculoskeletal health Alessandro Antonioli1, T. Raiteri2, A. Provera1, S. Reano3, S. Tini1, S. Sutti1, N. Filigheddu3, F. Prodam1 | 1Department of Health Sciences, University of Piemonte Orientale, Novara, Italy; 2Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 3Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
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Abstract 101 | Magistral lesson: the role played by sleep physiology and its disruption in stomatognathic and systemic disorders Luca Imeri | Department of Health Sciences, University of Milan Medical School, San Paolo University Hospital, Milan, Italy.
161Downloads: 51 -
Frailty: future prospectives in rehabilitation medicine
1202Downloads: 880HTML: 19 -
27 | Polymeric nanoparticles as a favorable delivery system to enhance the anti-inflammatory action of n-palmitoylethanolamide, an endocannabinoid-like molecule E. Maretti1, C. Rustichelli1, B. Recchia1, G. Battaglia, E. de Nicola1, C. Fuoco2, A. Votta3, C. Gargioli2, E. Ferraro3, E. Leo1, Susanna Molinari1 | 1Dept. of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy; 2Dept. Of Biology, Tor Vergata Rome University, Rome, Italy; 3Dept. of Biology, University of Pisa, Pisa, Italy.
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15 | GDF5 therapeutic potential for Duchenne muscular dystrophy C. Gentil, A. Bourguiba, A. Vergnol, B. Cadot, Z. Guesmia, L. Saillard, P. Meunier, S. Falcone, L. Giordani, France Pietri-Rouxel | Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
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Abstract 070 | Significant decrease of adiponectin plasmatic levels following two different programs of resistance training in healthy and well-trained young adults Eleonora Martegani,1|2, Luigi Marano 1|2, Sara Missaglia 1|2, Aurora Daniele 3|4, Marta Mallardo 4|5, Ersilia Nigro 4|6, Ferdinando Cereda 7, Daniela Tavian 1|2 | 1Laboratory of Cellular Biochemistry and Molecular Biology, CRIBENS, Università Cattolica del Sacro Cuore, Milan, Italy; 2Department of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy; 3Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli “Federico II” , Napoli, Italy; 4CEINGE Biotecnologie Avanzate ”Franco Salvatore” Scarl, Napoli, Italy; 5Department of Education and Sport Sciences Università telematica Pegaso Napoli, Italy; 6Dipartimento di Scienze e Tecnologie Ambientali, Biologiche, Farmaceutiche, Università della Campania “Luigi Vanvitelli”, Caserta, Italy; 7Department of Education, Catholic University of Sacred Heart, Milan, Italy.
124Downloads: 60 -
Abstract 040 | Short-term bed rest shifts DNA methylation age in a sex-specific manner: implications for mobility medicine Sofia Pavanello 1, Luana Cannella 1, Sara De Vidi 1, Gabriele Dolfi 1, Manuela Campisi 1, Marco V. Narici 2 | 1Department of Cardio-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy; 2Department of Biomedical Sciences, University of Padova, Padua, Italy.
163Downloads: 107 -
Abstract 019 | Circulating hematologic signatures distinguish low vs high physical function in older adults Rola S. Zeidan | Department of Physiology and Aging, University of Florida, Gainesville, FL, USA.
122Downloads: 82