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01 | INTEGRATED STRATEGIES FOR PLASTIC MANAGEMENT: MONITORING, BIOLOGICAL IMPACT, AND CIRCULAR PERSPECTIVES ROUND TABLE REPORT Giorgia Görner Enrile1|2, Antonietta Santoro3, Federica Scalia4, Stefania D’Angelo5, Annamaria Visco6, Andrea Pace7, Michele Torregrossa8, Dario Scalia9, Alessandro Aglialoro10, Salvatore Campanella10 | 1Siciliamedica.it; 2Ilsicilia.it; 3PI, Plastamination Project, University of Salerno, Italy; 4Human Anatomy, University Kore, Enna, Italy; 5Biochemistry, University Parthenope of Naples, Italy; 6Life Restart Project, University of Messina, Italy; 7Research and Technology Transfer, University of Palermo, Italy; 8Engineering, University of Palermo, Italy; 9Plastic Free Onlus Sicily, Italy; 10Regional Environmental Protection Agency of Sicily, Italy
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AIRBORNE MICROPLASTICS IN WORKPLACES: PRELIMINARY FINDINGS FROM A MULTI-SITE INVESTIGATION OF PLASTIC HANDLING AND PROCESSING FACILITIES Claudia CAMPANALE1, Leonardo BARLUCCHI2, Augusta PICCARDI1, Marcello DE ROSSI3, Giordano MORELLI3, Jacopo LA NASA2, Francesca MODUGNO2, Lorenzo PALUMBO1 | 1Dept. of Environment & Health, National Institute of Health (ISS), Rome; 2Department of Chemistry and Industrial Chemistry, University of Pisa; 3Laboratory of Industryal Hygiene – ASL Viterbo, Viterbo, Italy
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061 | Immunosafe(r)-by-design invertebrate-based nanoparticles: from engineered to biogenic structures for translational nanomedicine Annalisa Pinsino1, Giovanni Perconti1, Alessia Giannetto2, Andi Alijagic3 | 1Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy; 2Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy; 3Man-Technology-Environment Research Center MTM, Orebro University, Sweden.
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124 | Immunomodulatory effects of extracellular vesicles from invertebrate species on human cells Kristian Riolo1, Francesco Di Pietro1, Sabrina Oliva1, Claudia Mosca1, Valeria Stefanizzi1, Giovanna Montana2, Annalisa Pinsino2, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy.
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D-ASPARTATE ALLEVIATES THE TESTICULAR DAMAGE INDUCED BY POLYSTYRENE MICROPLASTICS Sara FALVO1, Giulia GRILLO1, Gabriella CHIEFFI BACCARI1, Alessandra SANTILLO1, Imed MESSAOUDI2, Maria Maddalena DI FIORE1, Alessandra BIASI3, Maria Rosaria AMBRUOSI3, Massimo VENDITTI3 | 1Dept. of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania L. Vanvitelli, Caserta, Italy; 2LR11ES41: Génétique, Biodiversité et Valorisation des Bioresources, Institut Supérieur de Biotechnologie, Université de Monastir, Monastir, Tunisia; 3Dept of Experimental Medicine, University of Campania ‘Luigi Vanvitelli’, Napoli, Italy
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072 | A standardized onion peel-derived bioactive ingredient attenuates palmitate-induced steatosis and oxidative stress in HepG2 cells Ilaria Di Gregorio1|2, Vincenzo Migliaccio2, Maria D’Elia1|3|4, Rita Celano1|3, Anna Lisa Piccinelli1|3, Luca Rastrelli1|3, Lillà Lionetti2|3 | 1Dept Pharmacy, University of Salerno, Salerno, Italy; 2Dept Chemistry and Biology “A Zambelli”, University of Salerno, Italy; 3National Biodiversity Future Center NBFC, Palermo, Italy; 4Dept Earth and Marine Sciences, University of Palermo, Italy.
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083 | HSV-1 replication and chemokines activation in human monocytes are suppressed by Pistacia vera l. extracts Rosamaria Pennisi1, Marianna Costa1|2, Paola Trischitta1|2, Giuseppina Mandalari1, Maria Teresa Sciortino1. | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy.
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096 | Hidden threats: trojan horse effects of microplastics enhance the toxicity of tire-wear chemicals in marine ecosystems Federica Davì, Roberta Fusco, Davide Di Paola | Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy.
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103 | Valorization of olive mill wastewaters for the recovery of polyphenols with reducing, radical scavenging and anti-inflammatory activities Francesco Longo1, Luisa Tesoriere1, Claudio Luparello1, Ignazio Restivo1, Federica Bellistrì1, Serena Indelicato1, David Bongiorno1, Rosi De Luca1, Giulia Abruscato1, Antonio Fabbrizio2, Salvatore Terrani3, Mirella Vazzana1, Vincenzo Arizza1, Manuela Mauro1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences DiSTA, University e Campus, Novedrate [CIO], Italy; 3The Wave Innovation Group, Verona, Italy.
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055 | Investigating microgravity’s dual impact through neuronal and cyanobacterial models: mechanistic insights into spirulina bioactivity and Parkinson’s disease pathology Mohammed Amine El Faqir1|2, Giuseppe Uras1, Alessia Manca2, Veronica Lentini2, Antonella Pantaleo2 | 1Department of Clinical Neuroscience, Institute of Neurology, University college London, UK; 2Department of Biomedical Science, University of Sassari, Italy.
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077 | Activation of the Keap1–Nrf2 axis underlies the antioxidant astrocytes protective effects of Boswellia sacra ethanolic extract: in vitro evidences supported by in silico analysis Graziella Serio1, Alessia Bono1, Roberto Chiarelli1, Marta Amato1, Mariangela Geraci1, Adriano Trapani1, Alessia Vermiglio1, Lorenza La Rosa1, Andrea Occhipinti2, Gabriella Schiera1, Antonino Lauria1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Abel Nutraceuticals SRL, Turin, Italy.
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086 | Kir4.1 channels at the crossroads of oxidative stress and presbycusis: redox imbalance, electrophysiological failure and quercetin-mediated rescue Sara Spinelli1, Alessia Remigante2, Angela Marino1, Rossana Morabito1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina, Italy.
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