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023 | Chaperone-associated macrophage polarization and extracellular matrix remodelling in human glioblastoma Leila Noori1|2, Rosario Barone1, Giuseppe Vergilio1|2, Maria Antonella Augello1, Giuseppa D’Amico1, Federica Scalia3, Pierlorenzo Veiceschi2, Giovanni Tringali2, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics [BiND], University of Palermo, Italy; 2Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS, Palermo, Italy; 3Department of Medicine and Surgery, Kore University of Enna, Italy.
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163 | SIX-2G as a novel compound to attenuate airway inflammation in cystic fibrosis through modulation of molecular chaperones Giuseppa D’Amico1, Federica Scalia2, Maria Antonella Augello1, Giusi Alberti1, Roberta Bivacqua3, Marilia Barreca3, Rosario Barone1, Francesco Cappello1, Paola Barraja3, Alessandra Montalbano3, Celeste Caruso Bavisotto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Department of Medicine and Surgery, Kore University of Enna, Italy; 3Department of Biological, Chemical, Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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014 | Development of a standardized and reproducible workflow for the generation and characterization of patient-derived glioblastoma spheroids Martina Di Marco1, Alessandra Maria Vitale1, Giuseppa D’Amico1, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Francesco Cappello1|2, Celeste Caruso Bavisotto1|2 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy.
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121 | Probiotics effect on brain-gut axis mediated by nanovescicles Alessandro Lo Giudice1, Giuseppa D’Amico1, Melania Ionelia Gratie1, Letizia Paladino2, Giusy Vultaggio1, Adelaide Carista1, Francesco Cappello1, Vita Di Stefano3, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy; 3Department of Biological, Chemical, and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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005 | Targeting the CCT5–AURKA–CEP55 axis in glioblastoma and neuroblastoma cell lines: antitumor effects of SA16 Maria Antonella Augello1, Giuseppa D’Amico1, Alessandra Maria Vitale1, Rosario Barone1, Simona Rapposelli3, Maciej Wnuk4, Francesco Cappello1|2, Celeste Caruso Bavisotto1|2, Federica Scalia5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy; 3Department of Pharmacy, University of Pisa, Italy; 4Faculty of Biotechnology, Collegium Medicum, University of Rzeszow, Poland; 5Department of Medicine and Surgery, Kore University of Enna, Italy.
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117 | Modulation of DNA methylation patterns and heat shock proteins following exercise and probiotic supplementation A. Boatta1|2, G. Messina1, A. Pagliaro3, A. Alioto3, C. Rossi3, L. Paladino4, F. Rappa6, F. Naselli5, F. Cappello6, R. Barone6, P. Proia3 | 1Department of Human Sciences and Promotion of Quality of Life, San Raffaele Roma Open University, Roma, Italy; 2Institute for Biomedical Research and Innovation, CNR, Palermo, Italy; 3Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Sciences and Human Movement, University of Palermo, Palermo, Italy; 4Department of Theoretical and Applied Sciences DiSTA, eCampus University, Novedrate, Italy; 5Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy; 6Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Palermo, Italy.
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093 | Beyond biodegradability: assessing the toxicological footprint of polylactic acid nanoplastics on zebrafish gastrointestinal tract development Francesca Chiara Cecala1, Giusy Vultaggio1, Martina Di Marco1, Alessandra Maria Vitale1, Rosario Barone1, Francesca Rappa1, Maria Denise Amico1, Erwin Pavel Lamparelli2, Giovanna Della Porta2, Antonietta Santoro2, Francesco Cappello1|4, Federica Scalia3, Marta Anna Szychlinska5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medicine and Surgery - Kore University of Enna, Italy; 4Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy; 5Department of Precision Medicine in Medical, Surgical and Critical Care MePreCC, University of Palermo, Italy.
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082 | Supplementation with Lactobacillus fermentum reversed fiber atrophy in a myopathy model by modulating IL-6, TNFα, and hsp60 levels, thereby enhancing muscle regeneration Martina Sausa1, Letizia Paladino2, Federica Scalia3, Francesco Paolo Zummo1, Giuseppe Vergilio1, Francesca Rappa1, Francesco Cappello1, Melania Ionelia Gratie1, Patrizia Proia4, Valentina Di Felice1, Antonella Marino Gammazza,5, Filippo Macaluso1, Rosario Barone1 | 1Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo; 2Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO]; 3Department of Medicine and Surgery, Kore University of Enna; 4Department of Psychology, Educational Science and Human Movement, University of Palermo; 5Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy.
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028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale1, Giuseppa D’Amico1, Martina Di Marco1, Giuseppina Poppa2, Pierlorenzo Maria Veiceschi3, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Paola Limoncelli2, Ilaria Giusti2, Vincenza Dolo2, Claudia Campanella1, Francesca Rappa1, Rosario Barone1, Giovanni Tringali3, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.
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