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039 | Age and growth of the mesopelagic fish Electrona risso (myctophidae) from the Strait of Messina (central Mediterranean sea) Calogero Fontana1, Alice Vaccaro2, Francesco Longo1, Danilo Malara3, Emanuela Fanelli2|4, Pietro Battaglia1|4 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2Università Politecnica delle Marche UNIVPM, Dipartimento di Scienze della Vita e dell’Ambiente, Ancona, Italy; 3Northern Territory Government of Australia, Department of Agriculture and Fisheries, Fisheries Division, Berrimah, NT, Australia; 4National Biodiversity Future Center, Palermo, Italy.
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056 | Thidiazuron exposure reprograms metabolic networks with lasting effects on growth and photosynthetic efficiency in Arabidopsis thaliana Manuela Giraldo-Acosta1, Giulia Giovanna Salerno2, Marino B. Arnao1, Cinzia Margherita Bertea3, Ada Ricci2, Giuseppe Mannino3 | 1Department of Plant Biology Plant Physiology, University of Murci, Spain; 2Department of Chemical, Life and Environmental Sustainability Sciences, University of Parma, Italy; 3Department of Life Sciences and Systems Biology, Plant Physiology Unit, University of Turin, Italy.
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028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale1, Giuseppa D’Amico1, Martina Di Marco1, Giuseppina Poppa2, Pierlorenzo Maria Veiceschi3, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Paola Limoncelli2, Ilaria Giusti2, Vincenza Dolo2, Claudia Campanella1, Francesca Rappa1, Rosario Barone1, Giovanni Tringali3, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.
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010 | Combining a gemcitabine-derived prodrug, GEM-C18, with nanoparticles to counteract acidic ph-dependent chemoresistance of pancreatic adenocarcinoma Francesca Fracasso, Marilena Ardone, Tiago Miguel Amaral Carvalho1|2, Barbara Rolando3, Silvia Arpicco3, Valeria Bincoletto3, Francesca Bianco4, Alessandra Fiorio Pla4, Daniela Isabel Abbrescia5, Ylenia Antonacci5, Chrysovalentinos Pousis5, Sharon Natasha Cox1, Flaviana Marzano5, Graziano Pesole1, Apollonia Tullo5, Stephan Joel Reshikn1, Rosa Angela Cardone1 | 1Dept of Biosciences, Biotechnology and Environment, University of Bari, ltaly; 2CICS-UBI-Health Sciences Research Center, Universidade da Beira Interior, Covilhã, Portugal; 3Dept. of Drug Science and Technology, University of Turin, ltaly; 4Dept of Life Sciences and Systems Biology, University of Turin, Italy 5Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies – IBIOM - CNR, Bari, Italy.
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135 | Genotype-dependent modulation of drought-induced responses in durum wheat through wheat–clover intercropping Noemi Gatti1, Moez Maghrebi1, Matteo Spada2, Giuseppe Mannino1, Stefania Astolfi2, Gianpiero Vigani1 | 1University of Turin, Department of Life Sciences and Systems Biology, Turin, Italy; 2University of Tuscia, Department of Agriculture and Forest Sciences, Viterbo, Italy.
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TOXIC EFFECTS OF POLYLACTIC ACID NANOPLASTICS ON IN VITRO MODELS OF ASTROCYTES AND NEURONS Marianna MARINO1, Martina LOMBARDI1-3, Raffaella D’AURIA1, Erwin Pavel LAMPARELLI1, Giovanna DELLA PORTA1,4, Marta Anna SZYCHLINSKA5, Federica SCALIA6, Francesco CAPPELLO6,7, Rosaria MECCARIELLO8, Andrea VIGGIANO1,4, Antonietta SANTORO1,4 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 2Theoreo Srl, Montecorvino Pugliano, SA, Italy; 3European Institute of Metabolomics - Fondazione EIM, Baronissi, SA, Italy; 4Interdepartmental Observatory for Scientific Health Initiatives in Environmental Legislation and Disease Prevention, SHIELD, University of Salerno, Italy; 5Department of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, Italy; 6Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 7Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; 8Department of Physical Sciences and Wellness, University of Naples Parthenope, Italy
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COMPARISON OF THE POTENTIAL CHRONIC TOXICITY OF POLYPROPYLENE AND POLYLACTIC ACID TO THE AMPHIPOD GAMMARUS AEQUICAUDA Francesca BIANDOLINO1, Ermelinda PRATO1, Amalia AMATO1,2, Loredana MANFRA2,5, Giovanni LIBRALATO2,3, Luisa ALBARANO3, Valerio ZUPO6, Maria COSTANTINI2 | 1National Research Council, Water Research Institute (IRSA-CNR), Taranto, Italy; 2Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy; 3Department of Biology, University of Naples Federico II, Naples, Italy; 4Stazione Zoologica Anton Dohrn, Department of Marine Animal Conservation and Public Engagement, Naples, Italy; 5Institute for Environmental Protection and Research (ISPRA), Rome, Italy; 6Stazione Zoologica Anton Dohrn, Department of Ecosustainable Marine Biotechnology, Ischia, Italy
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025 | Protect colorectal cancer: in vitro chemopreventive effects of bronte pistachio extracts on colorectal cancer cells Graziella Serio1, Roberto Chiarelli1, Giuseppe Mannino2, Samuele Davì1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Life Sciences and Systems Biology, Innovation Centre, University of Turin, Italy.
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164 | Analysis of the regenerative capacity and biochemical composition of pediatric platelet rich plasma in oronasal fistulas Anna Barbara Di Stefano1, Daniele Matta2, Francesca Toia1|2 | 1Department of Precision Medicine in Medical, Surgical and Critical Care, Plastic and Reconstructive Surgery Section, Palermo, Italy; 2BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, University of Palermo, Italy; 2Department of Precision Medicine in Medical, Surgical and Critical Care, Plastic and Reconstructive Surgery Section, University of Palermo, Italy.
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178 | Food-borne and environmental pathogens in wild ungulates from Sicily: implications for public health at the wildlife–livestock–human interface Elisa Maria Petta1, Valeria Vaglica1, Ilenia Giacchino1, Paola Galluzzo1, Sergio Migliore1, Federico Cangialosi1, Silvia Scibetta1, Elena Lo Bue1, Martina Imburgia1, Giuseppina Chiarenza1, Ettore Napoli2, Annalisa Guercio1, Francesca Grippi1, Valeria Blanda1 | 1Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri”, Palermo, Italy; 2Department of Veterinary Sciences, University of Messina, Italy.
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120 | Exploring CD36-dependent lipid uptake in melanoma–adipocyte communication mediated by extracellular vesicles Gaia Giannitti1, Kinga Kamińska2|3, Sara Marchesi1, Riccardo Garavaglia1, Ivan Preosto1, Małgorzata Grzesiak2, Fabrizio Fontana1 | 1Department of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", University of Milan, Italy; 2Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland; 3Department of Animal Biotechnology, University of Agriculture in Krakow, Poland.
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MATERNAL EXPOSURE TO ENDOCRINE DISRUPTORS AND INFANT DEVELOPMENT: FINDINGS FROM THE LIFE MILCH COHORT STUDY Silvia PATERLINI1, Maria Maddalena BRAMBILLA1, Francesca ALBERGHI2, Alessia ARDENGHI3, Mariateresa BELLANTONI1, Marta FONTANA2, Laura FILONZI3, Francesco NONNIS MARZANO3, Francesca NUTI4, Annalisa PELOSI1, Serafina PERRONE1, Silvia PETZA5, Roberta PINTUS5, Feliciana REAL-FERNANDEZ4, Vassilios FANOS5, Anna Maria PAPINI4, Maria E. STREET1,2, Paola PALANZA1 | 1Department of Medicine and Surgery, University of Parma (IT); 2Department of Obstetrics, Gynecology and Pediatrics, Azienda USL-IRCCS, Reggio Emilia (IT); 3Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma (IT); 4Department of Chemistry “Ugo Schiff”, University of Florence; 5Department of Surgical Sciences, University of Cagliari, Italy
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014 | Development of a standardized and reproducible workflow for the generation and characterization of patient-derived glioblastoma spheroids Martina Di Marco1, Alessandra Maria Vitale1, Giuseppa D’Amico1, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Francesco Cappello1|2, Celeste Caruso Bavisotto1|2 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy.
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141 | An inverted taxonomic approach unveils diversity of cladophoraceae (Chlorophyta) in two nature oriented reserves in northern Sicily (Italy) Matteo Vita1, Vincenzo Zammuto1, Mattia Soppelsa1, Fabio Mondello1, Salvatore Giacobbe2, Marina Morabito1, Antonio Manghisi1 | 1Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2CNR-IRBIM, Messina, Italy.
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054 | Biostimulant-mediated mitigation of hypoxic stress and recovery in lettuce under flooding conditions Chiara Dellapiana1, Chiara Agliassa2, Francesco Caldo1, Moez Maghrebi1, Valeria Contartese2, Giuseppe Mannino1, Gianpiero Vigani1 | 1Department of Life Sciences and Systems Biology, University of Turin, Italy; 2Green Has Italia SpA, Canale [AT], Italy.
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189 | Fluorescent analysis by confocal microscopy of lipid droplets as a marker of oocyte quality in Sarda sheep under different seasonal conditions Silvia Zaccardi1, Domenica Cocciolone1, Guido Macchiarelli1, Sara Succu2, Giovanni Giuseppe Leoni3, Maria Grazia Palmerini1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Veterinary Medicine, University of Sassari, Italy; 3Department of Biomedical Sciences, University of Sassari, Italy.
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119 | Insights into interleukin-8–dependent extracellular vesicle-mediated communication in melanoma Gaia Giannitti1, Kinga Kamińska2|3, Sara Marchesi1, Riccardo Garavaglia1, Ivan Preosto1, Małgorzata Grzesiak2, Fabrizio Fontana1 | 1Department of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", University of Milan, Italy; 2Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland; 3Department of Animal Biotechnology, University of Agriculture in Krakow, Poland.
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EXPLORING THE NEUROTOXIC POTENTIAL OF LDPE MICROPLASTICS: EVIDENCE IN VITRO AND IN VIVO ASSESSMENT Marilena MARRAUDINO1,2, Elena RICCI1,2, Silvia CHASSEUR1,2, Daniela RASA'1, Riccardo ROLANDO1, Stefano GOTTI1,2, Marina BOIDO1,2 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (TO), Italy; 2Department of Neuroscience ‘Rita Levi Montalcini’, University of Torino, Torino, Italy
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044 | Thyroid response to stress in illness Caretta caretta: a preliminary study Chiara Lomonaco1, Paola Galluzzo2|3, Giorgia Schirò1|3, Angelo Costanza2|3, Rosario Adragna3, Vincenzo Monteverde2|3, Claudia Giannetto1, Salvatore Dara2|3, Rosaria Disclafani2|4 | 1Dipartimento di Scienze Veterinarie, Polo Universitario dell’Annunziata, University of Messina, Italy; 2Centro Referenza Nazionale per il Benessere, Monitoraggio e Diagnostica delle malattie delle Tartarughe Marine CReTaM; 3Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri”, Palermo, Italy; 4Centro di Sostenibilità e Transizione Ecologica, University of Palermo, Italy.
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