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• 072 | A standardized onion peel-derived bioactive ingredient attenuates palmitate-induced steatosis and oxidative stress in HepG2 cells Ilaria Di Gregorio^1|2, Vincenzo Migliaccio², Maria D’Elia^1|3|4, Rita Celano^1|3, Anna Lisa Piccinelli^1|3, Luca Rastrelli^1|3, Lillà Lionetti^2|3 | ¹Dept Pharmacy, University of Salerno, Salerno, Italy; ²Dept Chemistry and Biology “A Zambelli”, University of Salerno, Italy; ³National Biodiversity Future Center NBFC, Palermo, Italy; ⁴Dept Earth and Marine Sciences, University of Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15324

  67

• 102 | Polylactic acid nanoparticles as metabolically active entities: a metabolomics and fluxomics perspective Martina Lombardi^1|2|3, Vera Abenante^2|3, Alessio Trotta^2|3, Erwin Pavel Lamparelli¹, Federica Montella¹, Giovanna Della Porta¹, Andrea Viggiano¹, Jacopo Troisi^1|2|3|4, Antonietta Santoro¹ | ¹Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; ²Theoreo Srl, Montecorvino Pugliano, Salerno, Italy; ³European Institute of Metabolomics - Fondazione EIM, Baronissi, Salerno, Italy; ⁴Department of Chemistry and Biology, “A Zambelli”, University of Salerno, Fisciano [SA], Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15354

  52

• 026 | Graphene oxide nanosystem for antisense miRNA-21 delivery in hepatocellular carcinoma Paola Trischitta¹, Rosamaria Pennisi¹, Maria Teresa Sciortino¹, Marta Kutwin² | ¹Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Dep of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, Warsaw, Poland.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15278

  54

• Tribulus terrestris fruit’s potential for synthesizing gold nanoparticles with remarkable biological prospects

  Nighat Nawaz, Irshad Ahmad, Simon G. Patching, Iqbal Hussain

  27-01-2025

  https://doi.org/10.4081/jbr.2025.12674

  5817

  Downloads: 1298

• 05 | ENGINEERED PARTICLES IN DRUG DELIVERY AND TISSUE ENGINEERING: IMPLICATIONS FOR PUBLIC HEALTH Anna Barbara Di Stefano¹, Simona Di Leo¹, Mara Franza^2|3, Francesca Toia^1|2|3 | ¹BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; ²Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; ³Section of Plastic and Reconstructive Surgery, Department of DAI chirurgico, Azienda Policlinico Paolo Giaccone, Palermo, Italy

  Società Italiana di Biologia Sperimentale

  20-04-2026

  https://doi.org/10.4081/jbr.2026.15574

  114

  Downloads: 23

• 114 | Mechanisms of antimony-induced intestinal injury under chronic low-dose exposure: evidence from Caco‑2 cells and protective role of cyanidin-3-o-glucoside Federica Lina Salamone^1|2, Maria Sofia Molonia¹, Santi Trischitta¹, Antonella Saija¹, Francesco Cimino¹, Antonio Speciale¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ²Imbesi Foundation, Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15366

  61
• 

  The venom and the toxicity of Pelagia noctiluca (Cnidaria: Scyphozoa). A review of three decades of research in Italian laboratories and future perspectives

  Rossana Morabito, Angela Marino, Giuseppina La Spada, Luigi Pane, Gian Luigi Mariottini

  28-12-2015

  https://doi.org/10.4081/jbr.2015.5372

  2927

  Downloads: 1188
• 

  The protective effect of Matricaria pubescens extracts against alloxan-induced hyperglycemia in rats

  Kherraz Khaled, Ghemam Amara Djilani, Laoudj Hacen, Mahdid Mohmed, Chefrour Azedinne

  04-08-2022

  https://doi.org/10.4081/jbr.2022.10441

  1326

  Downloads: 487

• Effects of extra virgin olive oil phenols on HL60 cell lines sensitive and resistant to anthracyclines

  M. Crescimanno, M.V. Sepporta, E. Tripoli, C. Flandina, M. Giammanco, F.T. Tumminello, D. Di Majo, M. Tolomeo, M. La Guardia, G. Leto

  30-01-2009

  https://doi.org/10.4081/jbr.2009.4729

  1041

  Downloads: 680

• 100 | Tracking polystyrene nanoplastics by raman microscopy reveals intestinal and retinal toxicity Valentina Iezzi¹, Roberta Maria Ferri¹, Annamaria Iannetta², Ludovica Sulcanese², Tommaso Silvestrini², Vanessa D’Altilia², Giovanni Angelozzi², Federico Perrella³, Carino Ferrante⁴, Giulia Fioravanti³, Monia Perugini², Elisabetta Benedetti¹ | ¹Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; ²Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Italy; ³Department of Physical and Chemical Sciences University of L’Aquila, Italy; ⁴CNR-SPIN, c/o department of Physical and Chemical Sciences University of L’Aquila, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15352

  53
• 

  Effects of altered gravity induced by clinorotation on the cholinesterase activity of the non-sentient model Paramecium primaurelia (Protozoa)

  Francesca Sardi, Martina Rossi, Sara Ferrando, Maria Angela Masini, Federico Biggi, Andrea Amaroli

  23-05-2018

  https://doi.org/10.4081/jbr.2018.7034

  1219

  Downloads: 578

• 109 | Novel eco-sustainable approaches to prevent and mitigate emerging contaminants-induced physiological changes in a marine model organisms Cristiana Roberta Multisanti¹, Marina Russo², Paolo Pastorino³, Giuseppe Piccione¹, Federica Impellitteri¹, Caterina Faggio^4|5 | ¹Dept of Veterinary Sciences, University of Messina, Messina, Italy; ²Dept of Chemical, Biological, Pharmaceutical, and Environmental Sciences, Messina Institute of Technology c/o, University of Messina, Messina, Italy; ³Zooprophylactic Institute of Piedmont, Liguria and Valle d'Aosta, Turin, Italy; ⁴Dept of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ⁵Dept of Eco-sustainable Marine Biotechnology, SZN Anton Dohrn, Naples, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15361

  59

• Comparison and evaluation of the methods for measuring hemolytic activity of Stomolophus meleagris jellyfish tentacle extract

  Yongfang Wang, Yiran He, Fengling Yang, Yi Wang, Zhaoyun Peng, Liang Xiao, Marina Pozzolini, Yina Zhu

  29-03-2024

  https://doi.org/10.4081/jbr.2024.11682

  2207

  Downloads: 542

• 087 | Synergistic collapse of redox homeostasis in human hepatic and renal cells: perfluorooctane sulfonate as a priming factor for oxidative pathophysiology Graziano Vinci¹, Marika Cordaro², Rosanna Di Paola³ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy; ²Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy; ³Department of Veterinary Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15339

  48

• The effect of culture media and seeding densities on the human malignant testicular germ cell line (NT2/D1) growth pattern

  Rawabi S. Altuwayjiri, Ibtesam S. Almami

  05-02-2025

  https://doi.org/10.4081/jbr.2025.13148

  5662

  Downloads: 1047

• 086 | Kir4.1 channels at the crossroads of oxidative stress and presbycusis: redox imbalance, electrophysiological failure and quercetin-mediated rescue Sara Spinelli¹, Alessia Remigante², Angela Marino¹, Rossana Morabito¹ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15338

  64

• 015 | A flavonoid-rich extract of bergamot juice modulates redox homeostasis and apoptosis in colorectal cancer experimental models Martina Farina¹, Alessandro Maugeri², Michele Navarra¹ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Department of Veterinary Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15267

  76

• Estrogen receptor-dependent effects of bisphenol a

  P. Bulzomi, A. Bolli, M. Marino

  30-01-2011

  https://doi.org/10.4081/jbr.2011.4502

  1857

  Downloads: 786

• CDX2 Expression in ovarian teratomatous cells with intestinal differentiation

  M. Mora, L. Mastracci, F. Grillo, G. Gaggero, E. Fulcheri

  31-01-2006

  https://doi.org/10.4081/jbr.2006.8074

  491

  Downloads: 234

• 068 | In vitro modulation of inflammatory mediators by eggplant peel extracts from two cultivar Alessandra Armeli, Desirèe Bonfiglio, Serena Munaò, Giovanna Calabrese | Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15320

  55

• Histological method to study winter physiological dormancy in leaf buds of "San Castrese" and "Laycot" apricot, Prunus armeniaca L.

  N. Valentini, A. Ponso, E. Ruffa, G. Me, B. Dore

  30-01-2009

  https://doi.org/10.4081/jbr.2009.4791

  833

  Downloads: 613

• 097 | Pharmaceutical pollution in aquatic environments: effects of valsartan on Mytilus galloprovincialis Giorgia Giurlanda¹, Alessia Caferro¹, Mariacristina Filice¹, Maria Assunta Iovine¹, Alfonsina Gattuso¹, Federica Impellitteri², Caterina Faggio³, Maria Carmela Cerra¹, Sandra Imbrogno¹ | ¹Department of Biology, Ecology, and Earth Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy; ²Department of Veterinary Sciences, University of Messina, Italy; ³Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15349

  46

• 022 | Physiologic remodelling in 3D hepatocellular carcinoma models: temporal evolution from day 0 to day 9 Serena Munaò, Alessandra Armeli, Desirèe Bonfiglio, Giovanna Calabrese | Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences ChiBioFarAm, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15274

  66

• Histochemical characterization of human osteochondral tissue: comparison between healthy cartilage, arthrotic tissues, and cartilage defect treated with MACI technique

  F. Tessarolo, R. Tatti, M. Molinari, P. Dorigotti, R. Antolini, G. Nollo

  30-01-2011

  https://doi.org/10.4081/jbr.2011.4688

  977

  Downloads: 879
• 

  Nutrients formulation to maximize Ankistrodesmus sp. microalgal cell biomass and lipid productivities

  Wanida Pan-utai, Penjit Srinophakun, Wilasinee Inrung

  11-11-2019

  https://doi.org/10.4081/jbr.2019.8547

  1163

  Downloads: 843

• Morphological Patterns Identification in PET+ Aneurysmatic Lesions

  L. Abete, F. Sarocchi, D. Palombo, G. Spinella, C. Barisione, E. Fulcheri

  30-01-2010

  https://doi.org/10.4081/jbr.2010.4431

  782

  Downloads: 454
• 

  Survey on ethnobotanical uses of anti-cancer herbs in Southern region of Ilam, West Iran

  Mahmoud Bahmani, Amir Sasan Mozaffari Nejad, Naseer Ali Shah, Sayed Afzal Shah, Mahmoud Rafieian-Kopaei, Leila Mahmoodnia

  22-09-2017

  https://doi.org/10.4081/jbr.2017.5939

  1784

  Downloads: 1182

• On probiotic integration in the management of inflammation and the maintenance of the intestinal epithelial barrier’s integrity

  Giovanna Traina

  08-08-2024

  https://doi.org/10.4081/jbr.2024.12362

  1129

  Downloads: 503

• 014 | Development of a standardized and reproducible workflow for the generation and characterization of patient-derived glioblastoma spheroids Martina Di Marco¹, Alessandra Maria Vitale¹, Giuseppa D’Amico¹, Alessandro Lo Giudice¹, Francesca Chiara Cecala¹, Francesco Cappello^1|2, Celeste Caruso Bavisotto^1|2 | ¹Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; ²Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15266

  68

• Chlorella minutissima grown free and in alginate beads and cytotoxicity of algal extracts on L929 cells

  G.L. Mariottini, L. Pane

  31-01-2006

  https://doi.org/10.4081/jbr.2006.8081

  455

  Downloads: 277
• 

  A protocol combining current- and voltage-clamp provides a novel and useful three-dimensional representation of cardiac action potential

  Massimiliano Zaniboni, Francesca Cacciani

  10-01-2014

  https://doi.org/10.4081/jbr.2014.2134

  1324

  Downloads: 1284

• Serum Levels of Classical HLA Class I Antigen in HIV-Infected patients during antiretroviral therapy. Correlation with the clinical outcome

  G. Murdaca, P. Cagnati, F. Puppo

  30-01-2009

  https://doi.org/10.4081/jbr.2009.4793

  807

  Downloads: 599

• Possible evidence of pregnancy and or famine in an ancient nubian female

  John Denton, Jennifer Mann, Ann Rosalie David

  31-12-2005

  https://doi.org/10.4081/jbr.2005.10098

  323

  Downloads: 175

• Oxidative stress and mitochondria damage contribute to silica nanoparticle-induced cytotoxicity in human endothelial cells

  S. Punzoni, V. Sanna, P. Bandiera, A. Montella, S. Uzzau, M. Sechi, G. Pintus

  30-01-2010

  https://doi.org/10.4081/jbr.2010.4465

  1175

  Downloads: 547
• 

  Comparative study of estrogen receptor α, β mRNA expressions of endometriosis and normal endometrium in women and analysis of potential synthetic anti-estrogens in silico

  Eldafira Eldafira, Abinawanto Abinawanto, Luthfiralda Sjahfirdi, Asmarinah Asmarinah, Purnomo Soeharso, Muharam Muharam, Vivitri D. Prasasty, Dwi A. Pujianto

  28-11-2018

  https://doi.org/10.4081/jbr.2018.7550

  1505

  Downloads: 606

• MICROPLASTICS IN EDIBLE PLANTS: AN UNDERESTIMATED RISK IN THE HUMAN FOOD CHAIN Pasquale PERRONE, Stefania D’ANGELO | Department of Medical, Movement, and Wellbeing Sciences, Parthenope University of Naples, Naples, Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14537

  533

• Molecular mechanisms mediating the neuroproyective effects of quinacrine and minocycline on cell death induced by the prion protein fragment 90-231 (hPrP90-231)

  V. Villa, A. Corsaro, S. Thellung, A. Simi, M. Nizzari, M. Tonelli, V. Boido, A. Aceto, T. Florio

  30-01-2011

  https://doi.org/10.4081/jbr.2011.4689

  992

  Downloads: 624

• Can Endocrine disrupters interfere with Ca2+ homeostasis in invertebrate cells?

  L. Canesi, B. Marchi, G. Mancinelli, R. Fabbri, F. Caprì, F. Dondero, A. Viarengo, G. Gallo

  30-01-2010

  https://doi.org/10.4081/jbr.2010.4435

  829

  Downloads: 654
• 

  Characterization of high frequency of recombination strains selected by integrative suppression of F’lac in dnaA, gyrA and gyrB temperature sensitive mutants

  Eugenio A. Debbia, Anna Marchese

  16-10-2017

  https://doi.org/10.4081/jbr.2017.6595

  898

  Downloads: 552

• 155 | Mitochondrial dynamics and therapeutic insights in spinal muscular atrophy: effects of MFN2 boosting in motoneurons and human fibroblasts Francesco Paolo Zummo¹, Serena Stanga¹, Letizia Paladino², Maria Beltran³, Francesco Fedeli⁴, Maria Rosa Soler³, Fabio Bucchieri⁵, Marina Boido¹ | ¹Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy; ²E-Campus University, Palermo, Italy; ³Neuronal Signaling Unit, Experimental Medicine Department, University of Lleida-IRBLleida, Lleida, Spain; ⁴University of Pavia, Italy; ⁵Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15407

  42

• Somatostatin receptor 1,2 and 5 activation leads to C6 glioma growth arrest in vitro and in vivo; analysis of the intracellular pathways involved

  M. Gatti, A. Pattarozzi, R. Würth, F. Angeletti, F. Barbieri, T. Florio

  31-01-2011

  https://doi.org/10.4081/jbr.2011.4649

  878

  Downloads: 681

• Insulin does not reverse neither exalt the effects of modeled gravity on the metabolism of normal and transformed cultured cells

  R. Coinu, G. Palumbo

  31-01-2006

  https://doi.org/10.4081/jbr.2006.8092

  377

  Downloads: 212

• 118 | Perinatal tissue-derived extracellular vesicles for diabetic wound healing: a translational proposal Mattia Biondo¹, Laura Tomasello², Giuseppina Biscari¹, Grazia L. Di Grado², Calogero Fiorica¹, Fabio S. Palumbo¹, Marian Mellen³, Ismael Santa-Maria³, Antonio S. Laganà², Maite Iglesias³, Giovanna Pitarresi¹, Giuseppe Pizzolanti^2|4 | ¹Dept of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; ²Dept of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties PROMISE, University of Palermo, Italy; ³Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Madrid, Spain; ⁴ATeN Center, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15370

  45
• 

  K:D-Rib: cancer cell proliferation inibitor and DNAzyme folding promoter

  Luca Bruni, Simonetta Croci

  10-01-2014

  https://doi.org/10.4081/jbr.2014.2135

  1497

  Downloads: 1305

• The remodeling of BRGI, the ATPase subunit of SWI/SNF complex, induces senescence in mesenchymal stem cells

  N. Alessio, T. Squillaro, A. Giordano, U. Galderisi, L. Bagella

  30-01-2010

  https://doi.org/10.4081/jbr.2010.4466

  683

  Downloads: 453
• 

  Expression of p53 and p21 in bladder carcinoma of Iraqi patients

  Rawaa Al Chalabi, Shahlaa M. Salih, Sajid Saad, Hayder Jawad

  24-06-2019

  https://doi.org/10.4081/jbr.2019.7742

  1052

  Downloads: 547

• PRELIMINARY RESULTS ON MICROPLASTIC AND NANOPLASTIC IMPACT IN VIRUS AND BACTERIAL REPLICATION Nicoletta CAPUANO^1,2, Alessia GIANNATTASIO³, Noemi CAFA’^1,2, Anna BARBATO^1,2, Mariarosa SCOGNAMIGLIO⁴, Vincenzo BELGIORNO⁵, Luca RINALDI^6, Veronica FOLLIERO^1,2, Antonio BUONERBA³, Gianluigi FRANCI^1,2 | ¹Dipartimento di Medicina, Chirurgia e Odontoiatria, Scuola Medica Salernitana, Università degli Studi di Salerno, Baronissi (SA), Italia; ²UOS di Microbiologia e Virologia, AOU San Giovanni di Dio e Ruggi D’Aragona, Salerno, Italia; ³Dipartimento di Chimica e Biologia, Università degli Studi di Salerno, Fisciano (SA), Italia; ⁴Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA), Italia; ⁵Dipartimento di Ingegneria Civile, Università degli Studi di Salerno, Fisciano (SA), Italia; ⁶Dipartimento di Medicina e Scienze della Salute, Università degli Studi del Molise, Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14541

  156

• 134 | Living with mold: a growing problem for urban biodiversity Andrea Furlan¹, Paolo Bonivento² | ¹Nanocoatings Research, Trieste, Italy; ²Istituto di Studi Europei “A. De Gasperi”, Roma, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15386

  49

• 057 | Bioactive metabolites from antarctic sponge-associated bacteria: bioactivity and cytotoxic assessment Claudia Gravagno^1|2, Stefano Putaggio², Teresa Romeo^2|3, Annamaria Russo², Carmen Rizzo^2|4, Ester Tellone², Angelina Lo Giudice⁴ | ¹Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; ²University of Messina, Italy; ³National Institute for Environmental Protection and Research, Milazzo [ME], Italy; ⁴National Research Council, Institute of Polar Sciences, Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15309

  44

• MICROFLUIDIC SYNTHESIS OF PLA NANOPARTICLES: COMPARISON OF DIFFERENT SYSTEMS TO ACHIEVE HIGH SCALABILITY AND BATCH-TO-BATCH REPRODUCIBILITY Federica MONTELLA , Erwin Pavel LAMPARELLI, Giovanna DELLA PORTA | Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi (SA), Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14577

  214