Parry-Romberg syndrome associated with ataxia: description of a patient improved after neurorehabilitation
Abstract
Parry-Romberg Syndrome (PRS) is a rare condition that can affect the musculoskeletal system, resulting in progressive motor disabilities. The existing literature provides limited evidence regarding physical therapy interventions for PRS. We present a case of a 69-year-old woman diagnosed with PRS with associated ataxia treated with a neurorehabilitative program aimed at improving motor function and balance. We administered various functional scales (SPPB, Tampa Scale of Kinesiophobia, Berg Balance Scale, and Tinetti Scale). Additionally, a standardized gait analysis was conducted in our Gait and Motion Laboratory. Following neurorehabilitative therapy, the patient exhibited significant positive changes in various motor outcomes, as demonstrated by improvements in scores on standardized tests (SPBB, Berg, TSK and Tinetti scales when compared pre- and post-treatment), as well as enhancements in biomechanical parameters and quality of life (FIM, SF-12). This case report suggests that neurorehabilitative therapy can be beneficial in improving motor function and balance in PRS patient, as well as other rare condition associated with disabilities.
References
- 1. Schultz KP, Dong E, Truong TA, Maricevich RS. Parry Romberg Syndrome. Clin Plast Surg 2019;46:231-7. DOI: https://doi.org/10.1016/j.cps.2018.11.007
- 2. Sudarshan R, Annigeri RG. Parry Romberg syndrome. Wien Klin Wochenschr 2010;122:606. DOI: https://doi.org/10.1007/s00508-010-1482-2
- 3. Patel H, Thakkar C, Patel K. Parry-romberg syndrome: a rare entity. J Maxillofac Oral Surg 2010;9:247-50. DOI: https://doi.org/10.1007/s12663-010-0103-y
- 4. Van der Cruyssen F, Meeus J, Schoenaers J, et al. Parry-Romberg syndrome: a mini review. Acta Dermatovenerol Alp Pannonica Adriat 2020;29:193-9. DOI: https://doi.org/10.15570/actaapa.2020.39
- 5. Yu BF, Dong LP, Dai CC, Wei J. Genetic variations in patient with Parry-Romberg syndrome. Sci Rep 2023;13:400. DOI: https://doi.org/10.1038/s41598-023-27597-1
- 6. Wong M, Phillips CD, Hagiwara M, Shatzkes DR. Parry Romberg Syndrome: 7 Cases and Literature Review. AJNR Am J Neuroradiol 2015;36:1355-61. DOI: https://doi.org/10.3174/ajnr.A4297
- 7. Kumar M, Singla R, Singh G, et al. Parry Romberg Syndrome: A Case Report and an Insight Into Etiology. Cureus 2023;15:e41465. DOI: https://doi.org/10.7759/cureus.41465
- 8. Budrewicz S, Koszewicz M, Koziorowska-Gawron E, et al. Parry-Romberg syndrome: clinical, electrophysiological and neuroimaging correlations. Neurol Sci 2012;33:423-7. DOI: https://doi.org/10.1007/s10072-011-0756-4
- 9. Parry Romberg syndrome: A long-term retrospective cohort study of 10 patients. Oral Maxillof Surg Cases 2018;4:73-83. DOI: https://doi.org/10.1016/j.omsc.2018.04.004
- 10. Lee YJ, Chung KY, Kang HC, et al. Parry-Romberg syndrome with ipsilateral hemipons involvement presenting as monoplegic ataxia. Korean J Pediatr 2015;58:354-7.
- 11. Sharma PK, Sekar A, Amir AP, Prabhu ALR. Parry-Romberg syndrome: A case report and literature review. Radiol Case Rep 2024;19:2230-8. DOI: https://doi.org/10.1016/j.radcr.2024.02.053
- 12. Aydın H, Yologlu Z, Sargın H, Metin MR. Parry-Romberg syndrome. Physical, clinical, and imaging features. Neurosciences (Riyadh) 2015;20:368-71. DOI: https://doi.org/10.17712/nsj.2015.4.20150142
- 13. de Vasconcelos Carvalho M, do Nascimento GJ, Andrade E, et al. Association of aesthetic and orthodontic treatment in Parry-Romberg syndrome. J Craniofac Surg 2010;21:436-9. DOI: https://doi.org/10.1097/SCS.0b013e3181cfe917
- 14. Lee YJ, Chung KY, Kang HC, et al. Parry-Romberg syndrome with ipsilateral hemipons involvement presenting as monoplegic ataxia. Korean J Pediatr 2015;58:354-7. DOI: https://doi.org/10.3345/kjp.2015.58.9.354
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