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09 | POLY(LACTIC ACID) PLASTICS CONTAMINATION (PLASTINATION): ORGAN INJURIES AND UNDERLINING MOLECULAR MECHANISMS: EVIDENCE FROM IN VIVO ZEBRAFISH MODEL Marta A. Szychlinska1, Federica Scalia2, Martina Di Marco3, Giusy Vultaggio3, Maria Denise Amico3, Fabiano Capparucci4, Carmelo Iaria4, Marianna Marino5, Erwin Pavel Lamparelli5, Giovanna Della Porta5, Francesca Rappa3, Antonella Marino Gammazza3, Rosario Barone3, Antonino Testa6, Rosaria Meccariello7, Antonietta Santoro5, Francesco Cappello3 | 1Department of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, Italy; 2Department of Medicine and Surgery - Kore University of Enna, Italy; 3Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Italy; 4Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Italy; 5Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 6Department of Biological and Pharmaceutical Environmental Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Caserta, Italy; 7Department of Movement and Wellness Sciences, Parthenope University of Naples, Italy
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05 | ENGINEERED PARTICLES IN DRUG DELIVERY AND TISSUE ENGINEERING: IMPLICATIONS FOR PUBLIC HEALTH Anna Barbara Di Stefano1, Simona Di Leo1, Mara Franza2|3, Francesca Toia1|2|3 | 1BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; 2Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; 3Section of Plastic and Reconstructive Surgery, Department of DAI chirurgico, Azienda Policlinico Paolo Giaccone, Palermo, Italy
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185 | From mycelium to medicine: cytotoxic effects of Ganoderma adspersum extracts in renal cancer cells Maria Noemi Sgobba1, Nikola Schlosserova1|2, Biagia Musio3, Federica Mastropirro1, Antonio Radesco4, Maria Favia5, Simona Marianna Sanzani4, Stefano Todisco3, Mariateresa Volpicella1, Anna De Grassi1, Vito Gallo3, Elena Ciani1, Ciro Leonardo Pierri6, Jakub Treml7, Lorenzo Guerra1 | 1Department of Biosciences, Biotechnologies and Environment, University of Bari, Italy; 2Department of Chemistry and Biochemistry, Faculty of AgriSciences, Mendel University in Brno, Czech Republic; 3Department of Civil, Environmental, Land, Building Engineering and Chemistry DICATECh, Polytechnic University of Bari, Italy; 4Department of Soil, Plant and Food Sciences, University of Bari, Italy; 5Department of Translational Biomedicine and Neurosciences DiBraiN, University of Bari, Italy; 6Department of Pharmacy – Pharmaceutical Sciences, University of Bari, Italy; 7Department of Molecular Pharmacy, Faculty of Pharmacy, Masaryk University, Brno, Czech Republic.
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POLYLACTIC ACID (PLA) PRODUCED FROM BREWER'S SPENT GRAIN (BSG): SUSTAINABLE PRODUCTION AND BIOMEDICAL APPLICATIONS Mario RUGGIERO, Filomena MAZZEO | Università degli Studi di Napoli Parthenope, Italy
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EVALUATING ENDOCRINE AND OXIDATIVE EFFECTS OF POLYLACTIC ACID NANOPLASTICS (PLA-NPs) ON BREAST CELL MODELS Maria Denise AMICO1, Antonietta SANTORO2, Erwin Pavel LAMPARELLI2, Giovanna DELLA PORTA2, Magdalena GORSKA-PONIKOWSKA3,4,5, Francesca RAPPA1,5, Fabio BUCCHIERI1, Francesco CAPPELLO1,5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medical Chemistry, Medical University of Gdansk, Poland; 4Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Germany; 5Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
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027 | Exploring the cooperative effect of osilodrostat and mitotane in 3D spheroid models of adrenocortical carcinoma Fabiola Vaglica1, Laura Tomasello1, Mattia Biondo2, Giuseppe Siragusa2, Giorgio Arnaldi1, Giuseppe Pizzolanti1|3, Valentina Guarnotta1 | 1Dept. of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties PROMISE, University of Palermo; 2Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo; 3ATeN Center, Palermo, Italy.
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013 | Innovative therapeutic approaches in solid tumors Alessia Dottore1, Rosalba Rossello2, Francesco Ferraù1 | 1UOC Oncologia Medica, Ospedale “San Vincenzo”, Taormina [ME], Italy; 2UOS Oncologia Medica, Ospedale “Cutroni Zodda”, Barcellona Pozzo di Gotto [ME], Italy.
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171 | Development of a 3D ex vivo model of human intestinal organoids for the study of inflammatory bowel diseases Giulia Maria Giorgia Lo Piano1, Massimo Biondo1, Adelaide Carista1, Domiziana Picone1, Stefano Burgio2|3, Alberto Fucarino4, Francesca Rappa1, Alessandro Pitruzzella1, Fabio Bucchieri1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy; 3Department of Medicine and Surgery, Kore University of Enna, Enna, Italy; 4Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Como, Italy.
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