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163 | SIX-2G as a novel compound to attenuate airway inflammation in cystic fibrosis through modulation of molecular chaperones Giuseppa D’Amico1, Federica Scalia2, Maria Antonella Augello1, Giusi Alberti1, Roberta Bivacqua3, Marilia Barreca3, Rosario Barone1, Francesco Cappello1, Paola Barraja3, Alessandra Montalbano3, Celeste Caruso Bavisotto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Department of Medicine and Surgery, Kore University of Enna, Italy; 3Department of Biological, Chemical, Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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183 | Pericyte-like adipose mesenchymal stem cells as a tool for blood-retinal barrier repair Ivana Roberta Romano1, Giuliana Mannino2, Alessio Canovai3, Rosario Amato3, Silvia Marracci3, Matteo Fallico4, Claudio Bucolo1, Rosario Giuffrida1, Maurizio Cammalleri3, Debora Lo Furno1 | 1Dept Biomedical and Biotechnological Sciences, Catania University, Catania, Italy; 2Faculty of Medicine and Surgery, Kore University, Enna, Italy; 3Department of Biology, Pisa University, Italy; 4Department of Ophthalmology, University of Catania, Italy.
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087 | Synergistic collapse of redox homeostasis in human hepatic and renal cells: perfluorooctane sulfonate as a priming factor for oxidative pathophysiology Graziano Vinci1, Marika Cordaro2, Rosanna Di Paola3 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy; 2Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy; 3Department of Veterinary Sciences, University of Messina, Italy.
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164 | Analysis of the regenerative capacity and biochemical composition of pediatric platelet rich plasma in oronasal fistulas Anna Barbara Di Stefano1, Daniele Matta2, Francesca Toia1|2 | 1Department of Precision Medicine in Medical, Surgical and Critical Care, Plastic and Reconstructive Surgery Section, Palermo, Italy; 2BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, University of Palermo, Italy; 2Department of Precision Medicine in Medical, Surgical and Critical Care, Plastic and Reconstructive Surgery Section, University of Palermo, Italy.
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079 | Pharmacological modulation of the STING pathway as an antiviral strategy against HSV-1 Federica Mastrolembo Barnà1|2, Paola Trischitta1|2, Marianna Costa1|2, Antonella Torre3, Alessia Onali3, Angela Pagliaro3, Alberto Deplano3, Elias Maccioni3, Rita Meleddu3, Simona Distinto3, Rosamaria Pennisi1, Maria Teresa Sciortino1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Dep of chemistry, biology and biotechnology, University of Perugia, Italy; 3Department of Life and Environmental Sciences, Section of Drug Sciences, University of Cagliari, University Campus, Monserrato [CA], Italy.
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066 | Modulation of oxidative stress and mitochondrial alteration in IL1β-stimulated human astrocytes: effects of extracts from leaves and rhizomes of Posidonia oceanica (L) Delile Giulia Abruscato1, Lucia Sileo2, Giulia Scanavino2, Manuela Mauro1, Francesco Longo1, Vincenzo Arizza1|3, Mirella Vazzana1|3, Claudio Luparello1|3, Ada Maria Tata2 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STeBICeF, University of Palermo, Italy; 2Department of Biology and Biotechnologies Charles Darwin, Sapienza- University of Rome, Italy; 3National Biodiversity Future Center NBFC, Palermo, Italy.
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160 | Short-term mild caloric restriction induces early adaptive metabolic and mitochondrial responses in the liver of healthy rats Martina Coletta1, Vincenzo Migliaccio1, Giuliana Panico2, Ilaria Di Gregorio1, Assunta Lombardi2, Lillà Lionetti1 | 1Dept Chemistry and Biology "A Zambelli", University of Salerno, Italy; 2Dept Biology, University of Naples Federico II, Naples, Italy.
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124 | Immunomodulatory effects of extracellular vesicles from invertebrate species on human cells Kristian Riolo1, Francesco Di Pietro1, Sabrina Oliva1, Claudia Mosca1, Valeria Stefanizzi1, Giovanna Montana2, Annalisa Pinsino2, Alessia Giannetto1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 2Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy.
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08 | NEURAL AND INTESTINAL IMPACT OF BIODEGRADABLE POLYLACTIC ACID NANOPLASTICS: RESULTS FROM THE PLASTAMINATION PROJECT Antonietta Santoro | Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Baronissi, Salerno, Italy; Interdepartmental Observatory for Scientific Health Initiatives in Environmental Legislation and Disease Prevention, SHIELD, University of Salerno, Italy
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094 | 2-octyl-2h-isothiazol-3-one and its role in zebrafish larvae neurogenesis and neuronal function Vanessa D’Altilia1, Ludovica Sulcanese1, Valentina Iezzi2, Silvana Zugaro2, Annamaria Iannetta1, Tommaso Silvestrini1|3, Elisabetta Benedetti2, Monia Perugini1. | 1Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Teramo, Italy; 2Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy; 3University of Camerino, International School of Advanced Studies, Camerino, Italy.
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088 | Investigating the role of Hsp60 in the pathophysiology of celiac disease Giusy Vultaggio1, Giuseppe Vergilio1|2, Letizia Paladino3, Rosario Barone1, Francesca Rappa1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy; 3Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy.
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