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117 | Modulation of DNA methylation patterns and heat shock proteins following exercise and probiotic supplementation A. Boatta1|2, G. Messina1, A. Pagliaro3, A. Alioto3, C. Rossi3, L. Paladino4, F. Rappa6, F. Naselli5, F. Cappello6, R. Barone6, P. Proia3 | 1Department of Human Sciences and Promotion of Quality of Life, San Raffaele Roma Open University, Roma, Italy; 2Institute for Biomedical Research and Innovation, CNR, Palermo, Italy; 3Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Sciences and Human Movement, University of Palermo, Palermo, Italy; 4Department of Theoretical and Applied Sciences DiSTA, eCampus University, Novedrate, Italy; 5Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy; 6Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Palermo, Italy.
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EVALUATION OF TRANS-EPITHELIAL PENETRATION AND MICROPLASTIC-INDUCED TISSUE DAMAGE IN A 3D MODEL OF HUMAN RESPIRATORY MUCOSA Adelaide CARISTA1, Domiziana PICONE1, Giulia Maria Giorgia LO PIANO1, Olga Maria MANNA2,3, Stefano BURGIO3,4, Giuseppa D’AMICO1, Margherita FERRANTE5, Gea OLIVERI CONTE5, Francesca RAPPA1, Rosario BARONE1, Fabio BUCCHIERI1, Alessandro PITRUZZELLA1, Alberto FUCARINO6 | 1Department of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), University of Palermo, Palermo, Italy; 2Pathologic Anatomy Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy; 3Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; 4Department of Medicine and Surgery, Kore University of Enna, Enna, Italy; 5Dipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate "G.F. Ingrassia", Università degli Studi di Catania, Igiene e Sanità Pubblica; 6Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Italy
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028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale1, Giuseppa D’Amico1, Martina Di Marco1, Giuseppina Poppa2, Pierlorenzo Maria Veiceschi3, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Paola Limoncelli2, Ilaria Giusti2, Vincenza Dolo2, Claudia Campanella1, Francesca Rappa1, Rosario Barone1, Giovanni Tringali3, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.
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014 | Development of a standardized and reproducible workflow for the generation and characterization of patient-derived glioblastoma spheroids Martina Di Marco1, Alessandra Maria Vitale1, Giuseppa D’Amico1, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Francesco Cappello1|2, Celeste Caruso Bavisotto1|2 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy.
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174 | Mummified lung tissue as a microbiological archive: an integrated approach to investigate past pulmonary microbial communities in 18th-19th century Europe Angela Mollica Nardo1, David Harasser2, Dario Piombino-Mascali3|4 | 1Life Sciences Center, Vilnius University, Vilnius, Lithuania; 2Institute for Mummy Studies, EURAC Research, Bolzano, Italy; 3Department of Anatomy, Histology, and Anthropology, Vilnius University, Vilnius, Lithuania; 4Department of Cultural Heritage, University of Salento, Lecce, Italy.
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153 | α-synuclein regulation in brain and bone marrow is releted to the differential expression of GATA1 transcription factor Viola Velardi1, Francesca Arciprete1, Claudia Caturano,1Rosa Alba Rana1, Romina Mancinelli2, Maria Zingariello1, Giorgio Vivacqua1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy.
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121 | Probiotics effect on brain-gut axis mediated by nanovescicles Alessandro Lo Giudice1, Giuseppa D’Amico1, Melania Ionelia Gratie1, Letizia Paladino2, Giusy Vultaggio1, Adelaide Carista1, Francesco Cappello1, Vita Di Stefano3, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy; 3Department of Biological, Chemical, and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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