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161 | Anle 138b inclusion complex with methyl-β-cylodextrin: a novel liquid formulation for administration in Parkinson disease Giuditta Colangelo1, Adriana Trapani2, Giuseppe Fracchiolla2, Rosa Angela Cardone3, Anna Patrizia De Nichilo2, Stefano Castellani4, Michele Maffia5, Massimo Conese1, Rosanna Mallamaci3 | 1Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 2Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, Bari, Italy; 3Department of Biosciences, Biotechnologies and Environment, University of Bari “Aldo Moro”, Bari, Italy; 4Department of Precision and Regenerative Medicine and Ionian Area DiMePRe-J, University of Bari “Aldo Moro”, Bari, Italy; 5Department of Biological and Environmental Science and Technologies DiSTeBA, University of Salento, Lecce, Italy.
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025 | Protect colorectal cancer: in vitro chemopreventive effects of bronte pistachio extracts on colorectal cancer cells Graziella Serio1, Roberto Chiarelli1, Giuseppe Mannino2, Samuele Davì1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Life Sciences and Systems Biology, Innovation Centre, University of Turin, Italy.
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099 | Mechanistic insights into the ecotoxicity of bisphenol analogues and their mixtures in marine mussels: oxidative stress and neuro-immune responses Antonella Iaconis1, Marika Cordaro2, Davide Di Paola1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 2Department of Biomedical, Dental and Morphological and Functional Imaging, University of Messina,, Italy.
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EFFECTS OF CO-EXPOSURE TO MICROPLASTICS AND CADMIUM ON THE BINDING OF PROTAMINE-LIKE PROTEINS TO DNA IN MYTILUS GALLOPROVINCIALIS Gennaro LETTIERI, Giulio SANTANIELLO, Simona AMORE, Carmela MARINARO, Marina PISCOPO | Dipartimento di Biologia, Università degli Studi di Napoli Federico II
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125 | Impact of 2D and 3D in vitro culture models on extracellular vesicles in human ovarian cancer Giulia Di Fazio1, Giuseppina Poppa1, Giuseppe Cammarata2, Sandra D’Ascenzo1, Vincenza Dolo1, Simona Taverna2, Ilaria Giusti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Institute of Translational Pharmacology IFT, National Research Council of Italy CNR, Palermo, Italy.
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077 | Activation of the Keap1–Nrf2 axis underlies the antioxidant astrocytes protective effects of Boswellia sacra ethanolic extract: in vitro evidences supported by in silico analysis Graziella Serio1, Alessia Bono1, Roberto Chiarelli1, Marta Amato1, Mariangela Geraci1, Adriano Trapani1, Alessia Vermiglio1, Lorenza La Rosa1, Andrea Occhipinti2, Gabriella Schiera1, Antonino Lauria1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Abel Nutraceuticals SRL, Turin, Italy.
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024 | In vitro analysis of molecular chaperone involvement in the radiological response of triple-negative breast cancer models Giusi Alberti1, Giuseppe Vergilio1, Domiziana Picone1, Denise Amico1, Rosario Barone1, Francesca Rappa1, Marco Calvaruso3, Gaia Pucci3, Luigi Minafra3, Antonella Marino Gammazza2 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostic BIND, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; 3Institute of Bioimaging and Complex Biological Systems-National Reasearch Council IBSBC-CNR, Cefalù-Palermo, Italy.
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097 | Pharmaceutical pollution in aquatic environments: effects of valsartan on Mytilus galloprovincialis Giorgia Giurlanda1, Alessia Caferro1, Mariacristina Filice1, Maria Assunta Iovine1, Alfonsina Gattuso1, Federica Impellitteri2, Caterina Faggio3, Maria Carmela Cerra1, Sandra Imbrogno1 | 1Department of Biology, Ecology, and Earth Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy; 2Department of Veterinary Sciences, University of Messina, Italy; 3Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.
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POLYLACTIC ACID (PLA) PRODUCED FROM BREWER'S SPENT GRAIN (BSG): SUSTAINABLE PRODUCTION AND BIOMEDICAL APPLICATIONS Mario RUGGIERO, Filomena MAZZEO | Università degli Studi di Napoli Parthenope, Italy
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064 | Sustainable extraction and functional characterization of bioactive compounds from Spirulina platensis for nutraceutical and cosmetic applications Carmen Sica1, Chiara Copat1, Gea Oliveri Conti1, Sheima Inoubli2, Margherita Ferrante1 | 1Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Italy; 2Department of Chemical Engineering, Universidade de Vigo, Campus de Ourense, Spain.
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