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MATERNAL EXPOSURE TO ENDOCRINE DISRUPTORS AND INFANT DEVELOPMENT: FINDINGS FROM THE LIFE MILCH COHORT STUDY Silvia PATERLINI1, Maria Maddalena BRAMBILLA1, Francesca ALBERGHI2, Alessia ARDENGHI3, Mariateresa BELLANTONI1, Marta FONTANA2, Laura FILONZI3, Francesco NONNIS MARZANO3, Francesca NUTI4, Annalisa PELOSI1, Serafina PERRONE1, Silvia PETZA5, Roberta PINTUS5, Feliciana REAL-FERNANDEZ4, Vassilios FANOS5, Anna Maria PAPINI4, Maria E. STREET1,2, Paola PALANZA1 | 1Department of Medicine and Surgery, University of Parma (IT); 2Department of Obstetrics, Gynecology and Pediatrics, Azienda USL-IRCCS, Reggio Emilia (IT); 3Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma (IT); 4Department of Chemistry “Ugo Schiff”, University of Florence; 5Department of Surgical Sciences, University of Cagliari, Italy
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01 | INTEGRATED STRATEGIES FOR PLASTIC MANAGEMENT: MONITORING, BIOLOGICAL IMPACT, AND CIRCULAR PERSPECTIVES ROUND TABLE REPORT Giorgia Görner Enrile1|2, Antonietta Santoro3, Federica Scalia4, Stefania D’Angelo5, Annamaria Visco6, Andrea Pace7, Michele Torregrossa8, Dario Scalia9, Alessandro Aglialoro10, Salvatore Campanella10 | 1Siciliamedica.it; 2Ilsicilia.it; 3PI, Plastamination Project, University of Salerno, Italy; 4Human Anatomy, University Kore, Enna, Italy; 5Biochemistry, University Parthenope of Naples, Italy; 6Life Restart Project, University of Messina, Italy; 7Research and Technology Transfer, University of Palermo, Italy; 8Engineering, University of Palermo, Italy; 9Plastic Free Onlus Sicily, Italy; 10Regional Environmental Protection Agency of Sicily, Italy
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056 | Thidiazuron exposure reprograms metabolic networks with lasting effects on growth and photosynthetic efficiency in Arabidopsis thaliana Manuela Giraldo-Acosta1, Giulia Giovanna Salerno2, Marino B. Arnao1, Cinzia Margherita Bertea3, Ada Ricci2, Giuseppe Mannino3 | 1Department of Plant Biology Plant Physiology, University of Murci, Spain; 2Department of Chemical, Life and Environmental Sustainability Sciences, University of Parma, Italy; 3Department of Life Sciences and Systems Biology, Plant Physiology Unit, University of Turin, Italy.
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180 | Shared pathways in experimental projects: research, territory, and scientific communities compared the example of the initiatives of the Regional Agency for Rural Development – Ersa (Friuli Venezia Giulia, Italy) Simona Rainis | Regional Agency for the Rural Development ERSA, Gorizia, Italy.
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128 | Human biodiversity (anthropological, agricultural, and urban) is closely connected to experimental biology studies to understand the present and pave the way for the future Paolo Bonivento | Istituto di Studi Europei “A. De Gasperi”, Roma, Italy.
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EXPOSITION TO PLASTIC AND ASSOCIATED-CHEMICALS IN NEURODEVELPMENTAL DISORDER: AN OVERVIEW Grazia Maria Giovanna PASTORINO, Francesca Felicia OPERTO | Department of Science of Health School of Medicine, University Magna Greacia of Catanzaro, Italy
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Adipokines in obesity and metabolic diseases
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POLY-LACTIC ACID NANOPLASTICS BIOCCUMULATE IN DEVELOPING ZEBRAFISH AND INDUCE EPIGENETIC CHANGES Massimo VENDITTI1, Marta Anna SZYCHLINSKA2, Valentina LOPARDO3, Federica SCALIA4, Marianna MARINO3, Erwin Pavel LAMPARELLI3, Giovanna DELLA PORTA3, Antonietta SANTORO3, Francesco CAPPELLO5, Rosaria MECCARIELLO6 | 1Department of Experimental Medicine, University of Campania “L. Vanvitelli”, Naples, Italy; 2Department of Precision Medicine in Medical, Surgical and Critical Care (MEPRECC), University of Palermo, Palermo, Italy; 3Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi, SA, Italy; 4Department of Medicine and Surgery, “Kore” University of Enna, Enna, Italy; 5Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; 6Department of Medical, Human Movement and Well-being Sciences, Parthenope University of Naples, Italy
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054 | Biostimulant-mediated mitigation of hypoxic stress and recovery in lettuce under flooding conditions Chiara Dellapiana1, Chiara Agliassa2, Francesco Caldo1, Moez Maghrebi1, Valeria Contartese2, Giuseppe Mannino1, Gianpiero Vigani1 | 1Department of Life Sciences and Systems Biology, University of Turin, Italy; 2Green Has Italia SpA, Canale [AT], Italy.
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028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale1, Giuseppa D’Amico1, Martina Di Marco1, Giuseppina Poppa2, Pierlorenzo Maria Veiceschi3, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Paola Limoncelli2, Ilaria Giusti2, Vincenza Dolo2, Claudia Campanella1, Francesca Rappa1, Rosario Barone1, Giovanni Tringali3, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.
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094 | 2-octyl-2h-isothiazol-3-one and its role in zebrafish larvae neurogenesis and neuronal function Vanessa D’Altilia1, Ludovica Sulcanese1, Valentina Iezzi2, Silvana Zugaro2, Annamaria Iannetta1, Tommaso Silvestrini1|3, Elisabetta Benedetti2, Monia Perugini1. | 1Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Teramo, Italy; 2Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy; 3University of Camerino, International School of Advanced Studies, Camerino, Italy.
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COMMERCIALLY-DERIVED MICROPLASTICS AFFECT EARLY LIFE STAGES IN PARACENTROTUS LIVIDUS SEA URCHIN Amalia AMATO1,2,3, Ermelinda PRATO4, Mariacristina COCCA5, Francesca BIANDOLINO4, Immacolata LIOTTA5,6, Simone GIOIA1,2,3, Roberta ESPOSITO1, Davide CARAMIELLO7, Loredana MANFRA1,8, Giovanni LIBRALATO1,2, Valerio ZUPO3, Maria COSTANTINI1 | 1Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Napoli, Italy; 2Department of Biology, University of Naples Federico II, Napoli, Italy; 3Stazione Zoologica Anton Dohrn, Department of Ecosustainable Marine Biotechnology, Ischia Marine Centre, Ischia, Italy; 4National Research Council, Water Research Institute (IRSA-CNR), Taranto, Italy; 5Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Pozzuoli, Napoli, Italy; 6Department of Chemical, Materials and Production Engineering, University of Naples “Federico II”, Napoli, Italy; 7Stazione Zoologica Anton Dohrn, Department of Marine Animal Conservation and Public Engagement, Naples, Italy; 8Institute for Environmental Protection and Research (ISPRA), Rome, Italy
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021 | Novel para-phenylenediamine-based derivatives as receptor tyrosine kinase-like orphan receptor 1 inhibitors: an in vitro preliminary characterization Maria Rosaria Miranda1, Gerardina Smaldone1, Francesca Di Matteo1, Valeria Napolitano1, Michela Aliberti1, Simona Musella1, Veronica Di Sarno1, Gianluigi Lauro1, Giuseppe Bifulco1, Giacomo Pepe1, Giovanna Aquino1, Mario Felice Tecce1, Isabel Maria Gomez-Monterrey2, Pietro Campiglia1, Carmine Ostacolo1, Alessia Bertamino1, Tania Ciaglia1, Vincenzo Vestuto1 | 1Department of Pharmacy, University of Salerno, Italy; 2Department of Pharmacy, University of Naples Federico II, Naples, Italy.
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113 | Ecotoxicological effects of bromuconazole in Oryzias latipes from embryos to adult endpoints Tania Russo1|2, Ilaria Olivito1, Iolanda Carratù2, Chiara Barone2, Ivan Conte2, Anna Di Cosmo2, Gianluca Polese2, Elvira Brunelli1 | 1Dipartimento di Biologia, Ecologia e Scienze della Terra, Università della Calabria, Rende [CS], Italy; 2Dipartimento di Biologia, Università di Napoli Federico II, Napoli, Italy.
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100 | Tracking polystyrene nanoplastics by raman microscopy reveals intestinal and retinal toxicity Valentina Iezzi1, Roberta Maria Ferri1, Annamaria Iannetta2, Ludovica Sulcanese2, Tommaso Silvestrini2, Vanessa D’Altilia2, Giovanni Angelozzi2, Federico Perrella3, Carino Ferrante4, Giulia Fioravanti3, Monia Perugini2, Elisabetta Benedetti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Italy; 3Department of Physical and Chemical Sciences University of L’Aquila, Italy; 4CNR-SPIN, c/o department of Physical and Chemical Sciences University of L’Aquila, Italy.
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189 | Fluorescent analysis by confocal microscopy of lipid droplets as a marker of oocyte quality in Sarda sheep under different seasonal conditions Silvia Zaccardi1, Domenica Cocciolone1, Guido Macchiarelli1, Sara Succu2, Giovanni Giuseppe Leoni3, Maria Grazia Palmerini1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Department of Veterinary Medicine, University of Sassari, Italy; 3Department of Biomedical Sciences, University of Sassari, Italy.
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134 | Living with mold: a growing problem for urban biodiversity Andrea Furlan1, Paolo Bonivento2 | 1Nanocoatings Research, Trieste, Italy; 2Istituto di Studi Europei “A. De Gasperi”, Roma, Italy.
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BIODEGRADABLE NANOPLASTIC: A TOOL FOR DRUG DELIVERY AND ENVIRONMENTAL CHALLENGE Enza TORINO1,2,3, Anna MENALE1, Samuele FIORENZA1,2, Simona SILVESTRI1,3 | 1University of Naples Federico II - Department of Chemical, Materials Engineering and Industrial Production; 2Interdepartmental Research Center on Biomaterial (CRIB); 3Fondazione Istituto Italiano di Tecnologia – Center for Advanced Biomaterials for Healthcare
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064 | Sustainable extraction and functional characterization of bioactive compounds from Spirulina platensis for nutraceutical and cosmetic applications Carmen Sica1, Chiara Copat1, Gea Oliveri Conti1, Sheima Inoubli2, Margherita Ferrante1 | 1Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Italy; 2Department of Chemical Engineering, Universidade de Vigo, Campus de Ourense, Spain.
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POLYSTYRENE NANOPARTICLES IN ZEBRAFISH: THEIR ROLE IN OCULAR STRESS AND LIPID METABOLIC IMBALANCE V. IEZZI1, F. PERRELLA2, S. ZUGARO1, R. M. FERRI1, A. IANNETTA3, L. SULCANESE3, T. SILVESTRINI3,4, M. PERUGINI3, E. BENEDETTI1, C. FERRANTE5 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila; 2Department of Physical and Chemical Sciences University of L’Aquila; 3Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo; 4Advanced Study “Theoretical and Applied Neuroscience” Preclinical, clinical and Translational neuroscience, University of Camerino, Italy; 5CNR-SPIN, c/o Department of Physical and Chemical Sciences University of L’Aquila, Italy
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053 | Collagen-based biomaterials for biologically relevant 3D in vitro vascular models Elena Delgrosso1, Franca Scocozza1, Michele Conti1|2 | 1Department of Civil Engineering and Architecture, University of Pavia, Italy; 23D and Computer Simulation Laboratory, IRCCS Policlinico San Donato, San Donato Milanese [MI], Italy.
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COMPARISON OF THE POTENTIAL CHRONIC TOXICITY OF POLYPROPYLENE AND POLYLACTIC ACID TO THE AMPHIPOD GAMMARUS AEQUICAUDA Francesca BIANDOLINO1, Ermelinda PRATO1, Amalia AMATO1,2, Loredana MANFRA2,5, Giovanni LIBRALATO2,3, Luisa ALBARANO3, Valerio ZUPO6, Maria COSTANTINI2 | 1National Research Council, Water Research Institute (IRSA-CNR), Taranto, Italy; 2Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy; 3Department of Biology, University of Naples Federico II, Naples, Italy; 4Stazione Zoologica Anton Dohrn, Department of Marine Animal Conservation and Public Engagement, Naples, Italy; 5Institute for Environmental Protection and Research (ISPRA), Rome, Italy; 6Stazione Zoologica Anton Dohrn, Department of Ecosustainable Marine Biotechnology, Ischia, Italy
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PERINATAL EXPOSURE TO BISPHENOL A AND BISPHENOL B CAN ALTER THE SEXUAL BEHAVIOUR AND REPRODUCTIVE SYSTEM OF OFFSPRING Elena RICCI1,2, Marilena MARRAUDINO1,2, Noemi CADORIN1, Iva SABOVIC3, Alberto FERLIN3, Stefano GOTTI1,2 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Torino, Italy; 2Department of Neuroscience ‘Rita Levi Montalcini’, University of Torino, Torino, Italy; 3Department of Medicine, Operative Unit of Andrology and Medicine of Human Reproduction, University of Padova, Padova, Italy
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044 | Thyroid response to stress in illness Caretta caretta: a preliminary study Chiara Lomonaco1, Paola Galluzzo2|3, Giorgia Schirò1|3, Angelo Costanza2|3, Rosario Adragna3, Vincenzo Monteverde2|3, Claudia Giannetto1, Salvatore Dara2|3, Rosaria Disclafani2|4 | 1Dipartimento di Scienze Veterinarie, Polo Universitario dell’Annunziata, University of Messina, Italy; 2Centro Referenza Nazionale per il Benessere, Monitoraggio e Diagnostica delle malattie delle Tartarughe Marine CReTaM; 3Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri”, Palermo, Italy; 4Centro di Sostenibilità e Transizione Ecologica, University of Palermo, Italy.
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061 | Immunosafe(r)-by-design invertebrate-based nanoparticles: from engineered to biogenic structures for translational nanomedicine Annalisa Pinsino1, Giovanni Perconti1, Alessia Giannetto2, Andi Alijagic3 | 1Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy; 2Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy; 3Man-Technology-Environment Research Center MTM, Orebro University, Sweden.
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171 | Development of a 3D ex vivo model of human intestinal organoids for the study of inflammatory bowel diseases Giulia Maria Giorgia Lo Piano1, Massimo Biondo1, Adelaide Carista1, Domiziana Picone1, Stefano Burgio2|3, Alberto Fucarino4, Francesca Rappa1, Alessandro Pitruzzella1, Fabio Bucchieri1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy; 3Department of Medicine and Surgery, Kore University of Enna, Enna, Italy; 4Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Como, Italy.
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091 | Increased vulnerability to experimental colitis following chronic low-dose exposure to Sicilian environmental contaminants Noemi Aloi1|2, Paolo Colombo2, Valeria Longo2, Rosa Serio1, Maria Grazia Zizzo1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, Università di Palermo, Italy; 2Institute for Biomedical Research and Innovation, National Research Council of Italy IRIB-CNR, Palermo, Italy.
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147 | Screening of novel metabotropic glutamate receptor 4-oriented molecules in an in vitro model of Parkinson’s disease Cristina Giuffré1, Miriana Scordino1, Giulia Urone1, Miriam Buttacavoli1, Alessandra Montalbano2, Marilia Barreca2, Roberta Bivacqua2, Paola Barraja2, Virginia Spano’2, Giuseppa Mudo’1, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy.
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014 | Development of a standardized and reproducible workflow for the generation and characterization of patient-derived glioblastoma spheroids Martina Di Marco1, Alessandra Maria Vitale1, Giuseppa D’Amico1, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Francesco Cappello1|2, Celeste Caruso Bavisotto1|2 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy.
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078 | Stress-driven Dhurrin accumulation in sorghum revealed by physiological and biochemical markers Alessio Giannilivigni1, Manuela Giraldo-Acosta2, Flavia Girolami3, Stefano Giantin4, Luca Carisio4, Carlo Nebbia3, Marino Bañón Arnao2, Alberico Franzin4, Giuseppe Mannino1. | 1Department of Life Sciences and Systems Biology, Plant Physiology Unit, University of Turin, Italy; 2Department of Plant Biology Plant Physiology, University of Murcia, Spain; 3Department of Veterinary Sciences, University of Turin, Grugliasco [TO], Italy; 4Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta IZSPLV, Turin, Italy; 5Green Has Italia Spa, Plant Physiology Unit, Canale [CN], Italy.
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Entertaining mummies: embalming for the sideshow
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167 | The importance of personalized oxygen-ozone dosing in systemic therapy: algorithmic solutions for regenerative medicine Antonio Galoforo1, Paolo Bonivento2 | 1Tavolo Tecnico “Salute ed Ambiente”, Intergruppo parlamentare “One Health”, Camera dei Deputati, Roma, Italy; 2RING - ODR Research Innovation Networking Generation, Organismo di Ricerca, Milano, Italy.
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036 | Diversity and composition of microbial communities associated with deep-sea marine litter Vittoria Dias1|2, Carmen Rizzo1|3, Cristina Pedà1, Pierpaolo Consoli1, Teresa Romeo1|3 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2University of Milano Bicocca, Milano, Italy; 3National Biodiversity Future Centre NBFC, Italy.
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104 | In vitro crosstalk between perfluorooctanoic acid–induced hypertrophic adipocytes and MCF-7 breast cancer cells Maria Sofia Molonia1, Federica Lina Salamone1|2, Santi Trischitta1, Antonella Saija1, Antonio Speciale1, Francesco Cimino1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; 2Imbesi Foundation, Messina, Italy.
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