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Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

Editors-in-Chief: Gian Luigi Mariottini - Antonella Marino Gammazza, Italy | eISSN 2284-0230 - pISSN 1826-8838

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  • EVALUATING ENDOCRINE AND OXIDATIVE EFFECTS OF POLYLACTIC ACID NANOPLASTICS (PLA-NPs) ON BREAST CELL MODELS Maria Denise AMICO1, Antonietta SANTORO2, Erwin Pavel LAMPARELLI2, Giovanna DELLA PORTA2, Magdalena GORSKA-PONIKOWSKA3,4,5, Francesca RAPPA1,5, Fabio BUCCHIERI1, Francesco CAPPELLO1,5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medical Chemistry, Medical University of Gdansk, Poland; 4Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Germany; 5Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14556
    204
  • 021 | Novel para-phenylenediamine-based derivatives as receptor tyrosine kinase-like orphan receptor 1 inhibitors: an in vitro preliminary characterization Maria Rosaria Miranda1, Gerardina Smaldone1, Francesca Di Matteo1, Valeria Napolitano1, Michela Aliberti1, Simona Musella1, Veronica Di Sarno1, Gianluigi Lauro1, Giuseppe Bifulco1, Giacomo Pepe1, Giovanna Aquino1, Mario Felice Tecce1, Isabel Maria Gomez-Monterrey2, Pietro Campiglia1, Carmine Ostacolo1, Alessia Bertamino1, Tania Ciaglia1, Vincenzo Vestuto1 | 1Department of Pharmacy, University of Salerno, Italy; 2Department of Pharmacy, University of Naples Federico II, Naples, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15273
    38
  • 145 | Synergistic effects of APP and Tau on neuronal miRNA regulation Laura M. De Plano1, Alessandra Saitta1, Antonella Caccamo1, Emanuele L. Sciuto1, Sabrina Conoci2, Salvatore Oddo1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Dipartimento di Chimica "Giacomo Ciamician", University of Bologna, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15397
    38
  • 028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale1, Giuseppa D’Amico1, Martina Di Marco1, Giuseppina Poppa2, Pierlorenzo Maria Veiceschi3, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Paola Limoncelli2, Ilaria Giusti2, Vincenza Dolo2, Claudia Campanella1, Francesca Rappa1, Rosario Barone1, Giovanni Tringali3, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15280
    46
  • RAT SERUM IMPROVES RAT PSEUDOISLET FORMATION AND INSULIN GENE EXPRESSION

    L. Lione, A. Puddu, A. Pedemonte, G.L. Viviani
    31-05-2024
    https://doi.org/10.4081/jbr.2001.12502
    165
    Downloads: 203
  • 083 | HSV-1 replication and chemokines activation in human monocytes are suppressed by Pistacia vera l. extracts Rosamaria Pennisi1, Marianna Costa1|2, Paola Trischitta1|2, Giuseppina Mandalari1, Maria Teresa Sciortino1. | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15335
    59
  • FROM PRISTINE TO LABORATORY-WEATHERED MICRO- AND NANOPLASTICS: INTERACTION WITH ENVIRONMENTAL CONTAMINANTS AND BIOLOGICAL EFFECTS Astrid SARACENI1, Barbara MOGNETTI1, Erika COTTONE1, Andrey Ethan RUBIN2, Maria Pia GALLO1, Yoav GOTHILF3, Ines ZUCKER2,4, Federica DAL BELLO5, Patrizia BOVOLIN1 | 1Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy; 2Porter School of Earth and Environmental Studies, Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel; 3Department of Neurobiology, The George S. Wise Faculty of Life Sciences and Sagol School of Neuroscience, Tel-Aviv University, Tel Aviv, Israel; 4School of Mechanical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel; 5Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14557
    213
  • 090 | Activation of Sirtuin-1 by Cipollotto Nocerino leaf extract protects HepG2 cells from lipotoxicity Vincenzo Vestuto1, Maria Rosaria Miranda1, Giovanna Aquino2, Tania Ciaglia1, Rodolfo Maria Abbate1, Giuseppina Amodio3, Manuela Giovanna Basilicata4, Mario Felice Tecce1, Luca Rastrelli1, Pietro Campiglia1, Michele Manfra5, Giacomo Pepe1 | 1Department of Pharmacy, University of Salerno, Italy; 2AREA Science Park, Laboratorio di Multi-omica Area Sud LAAS, Baronissi [SA], Italy; 3Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi [SA], Italy; 4Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy; 5Department of Science, University of Basilicata, Potenza, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15342
    92
  • 020 | A three-dimensional vascularized cancer model mimicking the tumor microenvironment for drug resistance studies Alessandra Lo Cicero1, Gabriele Lo Buglio1, Francesco La Monica1, Simona Campora1, Margot Lo Pinto2, Simone Dario Scilabra2, Giulio Ghersi1|3 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Palermo, Italy; 2Proteomics Group of RiMED Foundation, Research Department IRCCS ISMETT Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy; 3Abiel srl, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15272
    54
  • Inhibition study of proinflammatory factor with ethanolic extract of propolis on innate immunity from diabetes mellitus mice model

    Bambang Pristiwanto, Sutiman B. Sumitro, Muhammad S. Djati, Aris Soewondo, Hideo Tsuboi, Muhaimin Rifa’i
    12-02-2018
    https://doi.org/10.4081/jbr.2017.6733
    1035
    Downloads: 839
  • 062 | Enriched bioplastics with natural compounds as innovative hemocompatible biomaterials targeting red blood cells Stefano Putaggio, Annamaria Russo, Giuseppe Tancredi Patanè, Claudia Gravagno, Antonella Calderaro, Davide Barreca, Silvana Ficarra, Ester Tellone | Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15314
    61
  • Regulatory volume decrease in isolated nematocytes is affected by crude venom from the jellyfish Pelagia noctiluca

    Rossana Morabito, Silvia Dossena, Giuseppa La Spada, Angela Marino
    28-11-2014
    https://doi.org/10.4081/jbr.2014.4813
    1970
    Downloads: 762
  • 125 | Impact of 2D and 3D in vitro culture models on extracellular vesicles in human ovarian cancer Giulia Di Fazio1, Giuseppina Poppa1, Giuseppe Cammarata2, Sandra D’Ascenzo1, Vincenza Dolo1, Simona Taverna2, Ilaria Giusti1 | 1Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; 2Institute of Translational Pharmacology IFT, National Research Council of Italy CNR, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15377
    67
  • 010 | Combining a gemcitabine-derived prodrug, GEM-C18, with nanoparticles to counteract acidic ph-dependent chemoresistance of pancreatic adenocarcinoma Francesca Fracasso, Marilena Ardone, Tiago Miguel Amaral Carvalho1|2, Barbara Rolando3, Silvia Arpicco3, Valeria Bincoletto3, Francesca Bianco4, Alessandra Fiorio Pla4, Daniela Isabel Abbrescia5, Ylenia Antonacci5, Chrysovalentinos Pousis5, Sharon Natasha Cox1, Flaviana Marzano5, Graziano Pesole1, Apollonia Tullo5, Stephan Joel Reshikn1, Rosa Angela Cardone1 | 1Dept of Biosciences, Biotechnology and Environment, University of Bari, ltaly; 2CICS-UBI-Health Sciences Research Center, Universidade da Beira Interior, Covilhã, Portugal; 3Dept. of Drug Science and Technology, University of Turin, ltaly; 4Dept of Life Sciences and Systems Biology, University of Turin, Italy 5Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies – IBIOM - CNR, Bari, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15262
    60
  • 061 | Immunosafe(r)-by-design invertebrate-based nanoparticles: from engineered to biogenic structures for translational nanomedicine Annalisa Pinsino1, Giovanni Perconti1, Alessia Giannetto2, Andi Alijagic3 | 1Institute of Translational Pharmacology IFT, National Research Council CNR, Palermo, Italy; 2Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy; 3Man-Technology-Environment Research Center MTM, Orebro University, Sweden.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15313
    52
  • Monitoring magnesium efflux cyclic AMP-induced in HL60 cells by using a new hydroxyquinoline fluorescent chemosensor

    Chiara Marraccini, Azzurra Sargenti, Lucia Merolle, Concettina Cappadone, Giovanna Farruggia, Stefano Iotti
    10-01-2014
    https://doi.org/10.4081/jbr.2014.2137
    1196
    Downloads: 865
  • 070 | Role of bioactive extracts obtained from marine sources and agri-food industry by-products in ETosis modulation Federica Bellistrì1, Giulia Abruscato1, Manuela Perlotti1, Alessia Lo Muzzo1, Claudio Gargano1, Francesco Longo1, Manuela Mauro1, Roberto Chiarelli1, Vincenzo Arizza1|3, Claudio Luparello1|3, Gianluca Sarà2|3, Mirella Vazzana1|3 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Earth and Marine Sciences, Palermo, Italy; 3National Biodiversity Future Center, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15322
    60
  • 025 | Protect colorectal cancer: in vitro chemopreventive effects of bronte pistachio extracts on colorectal cancer cells Graziella Serio1, Roberto Chiarelli1, Giuseppe Mannino2, Samuele Davì1, Carla Gentile1 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 2Department of Life Sciences and Systems Biology, Innovation Centre, University of Turin, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15277
    40
  • BT3 molecules ligation enhances the proinflammatory responses of human monocytes and monocyte-derived dendritic cells

    R. Simone, A. Rabellino, G. Icardi, M. Bagnasco, G. Pesce, D. Olive, D. Saverino
    30-01-2011
    https://doi.org/10.4081/jbr.2011.4664
    849
    Downloads: 644
  • NANOPLASTICS AND IMMUNITY: INVESTIGATING THE EXTRACELLULAR MATRIX’S INFLUENCE ON MACROPHAGE INTERACTION WITH POLYSTYRENE NANOPARTICLES Marianna ROCA1, Naym BLAL1, Zeynep RENKLER2, Vincenzo GUARINO2, Antonia DI MOLA1, Antonio MASSA1, Ilaria DE MARTINO3, Velia SICILIANO3, Daniela GUARNIERI1 | 1Department of Chemistry and Biology, “Adolfo Zambelli”, University of Salerno; 2Institute of Polymers, Composites and Biomaterials, National Research Council of Italy; 3Synthetic and Systems Biology for Biomedicine Lab, Istituto Italiano di Tecnologia, Naples, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14561
    222
  • 168 | GLP‑1 receptor signaling directs adipogenic repression and thermogenic activation in human adipose-derived stem cells Carola Pia Giordano, Laura Tomasello, Luigi Di Rosa, Antonino Salvatore Fiore, Sonya Vasto, Sara Baldassano | Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15420
    78
  • 121 | Probiotics effect on brain-gut axis mediated by nanovescicles Alessandro Lo Giudice1, Giuseppa D’Amico1, Melania Ionelia Gratie1, Letizia Paladino2, Giusy Vultaggio1, Adelaide Carista1, Francesco Cappello1, Vita Di Stefano3, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy; 3Department of Biological, Chemical, and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15373
    41
  • 023 | Chaperone-associated macrophage polarization and extracellular matrix remodelling in human glioblastoma Leila Noori1|2, Rosario Barone1, Giuseppe Vergilio1|2, Maria Antonella Augello1, Giuseppa D’Amico1, Federica Scalia3, Pierlorenzo Veiceschi2, Giovanni Tringali2, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics [BiND], University of Palermo, Italy; 2Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS, Palermo, Italy; 3Department of Medicine and Surgery, Kore University of Enna, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15275
    64
  • Immunohistochemical evidence of HLA-G expression in extravillous trophoblast invading decidual tissues

    V. Prada, Y. Musizzano, M. Mora, F. Puppo, E. Fulcheri
    30-01-2010
    https://doi.org/10.4081/jbr.2010.4442
    1177
    Downloads: 572
  • Spontaneous electrical activity of guinea-pig sinoatrial cells under modulation of two different pacemaker mechanisms

    Francesca Cacciani, Massimiliano Zaniboni
    10-01-2014
    https://doi.org/10.4081/jbr.2014.2125
    1226
    Downloads: 1087
  • 147 | Screening of novel metabotropic glutamate receptor 4-oriented molecules in an in vitro model of Parkinson’s disease Cristina Giuffré1, Miriana Scordino1, Giulia Urone1, Miriam Buttacavoli1, Alessandra Montalbano2, Marilia Barreca2, Roberta Bivacqua2, Paola Barraja2, Virginia Spano’2, Giuseppa Mudo’1, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15399
    39
  • 076 | Iron-driven redox dysregulation fuels psoriatic signaling in CARD14 e138a mutant keratinocytes Cristiana Galeano1, Anna Martina Battaglia1, Emanuele Giorgio1, Lavinia Petriaggi1, Giuseppe Natali2, Flavia Biamonte1 | 1Laboratory of Biochemistry and Cell Biology, Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Italy; 2Department of Life Science, Magna Graecia University of Catanzaro, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15328
    44
  • 105 | The invasive crab Callinectes sapidus as a model for assessing sub-lethal effects of polyvinyl alcohol Alessandra Maganza1|2, Alice Gabetti1, Camilla Mossotto1|2, Alessia Merialdi1, Monia Renzi3, Francesca Provenza4, Serena Anselmi4, Antonia Concetta Elia2, Giorgia Zicarelli1, Annalisa Cotugno1, Giuseppe Esposito1, Caterina Faggio5|6, Marino Prearo1, Paolo Pastorino1 | 1The Veterinary Medical Research Institute for Piemonte, Liguria and Valle d’Aosta, Torino, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy; 3Bioscience Research Center, Orbetello, Italy; 4Department of Life Sciences, University of Trieste, Trieste, Italy; 5Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; 6Department of Eco-sustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Napoli, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15357
    51
  • Adipokines in obesity and metabolic diseases

    Marco Giammanco, Herbert R. Marini, Socrate Pallio, Manfredi Marco Giammanco, Giovanni Tomasello, Francesco Carini, Fabio Venturella, Gaetano Leto, Maurizio La Guardia
    13-01-2021
    https://doi.org/10.4081/jbr.2020.8915
    1091
    Downloads: 571
  • SWIMMING IN PLASTAMINATION: POLY-LACTIC ACID NANOPLASTICS AND SPERM FUNCTIONS Alberto CONTRI1, Massimo VENDITTI2, Alessia GLORIA1, Marianna MARINO3, Erwin Pavel LAMPARELLI3, Giovanna DELLA PORTA3, Antonietta SANTORO3, Rosaria MECCARIELLO4 | 1Department of Veterinary Medicine, University of Teramo; 2Department of Experimental Medicine, University of Campania “L. Vanvitelli”, Naples; 3Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi (SA); 4Department of Medical, Human Movement and Well-being Sciences, Parthenope University of Naples, Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14570
    201
  • 013 | Innovative therapeutic approaches in solid tumors Alessia Dottore1, Rosalba Rossello2, Francesco Ferraù1 | 1UOC Oncologia Medica, Ospedale “San Vincenzo”, Taormina [ME], Italy; 2UOS Oncologia Medica, Ospedale “Cutroni Zodda”, Barcellona Pozzo di Gotto [ME], Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15265
    53
  • 064 | Sustainable extraction and functional characterization of bioactive compounds from Spirulina platensis for nutraceutical and cosmetic applications Carmen Sica1, Chiara Copat1, Gea Oliveri Conti1, Sheima Inoubli2, Margherita Ferrante1 | 1Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Italy; 2Department of Chemical Engineering, Universidade de Vigo, Campus de Ourense, Spain.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15316
    58
  • Iron metabolism and peripheral eosinophil count do not correlate in the general population

    Mara De Amici, Riccardo Albertini, Fiorella Barocci, Tiziana Bosoni, Laura Maria Ciardelli, Annalisa De Silvestri, Gian Luigi Marseglia, Giorgio Ciprandi
    10-08-2023
    https://doi.org/10.4081/jbr.2023.11352
    2299
    Downloads: 639
  • 073 | Modulation of NLRP3 inflammasome and macrophage polarization by quantum molecular resonance in THP-1 cells Maria Giulia Di Battista1, Osama Elsallabi1, Benedetta Rizza1, Tiziano Lupi1, Alessandro Pozzato2, Paola Lanuti1, Antonia Patruno1 | 1Department of Medicine and Aging Sciences, University “G. d’Annunzio” of Chieti-Pescara, Italy; 2Telea Electronic Engineering Srl, Sandrigo [VI], Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15325
    47
  • Inhibitory effect of plant extracts on the cytotoxicity of eurytele nematocysts from Pelagia noctiluca

    Rossana Morabito, Laura Cornara, Giuseppina La Spada, Angela Marino, Gian Luigi Mariottini, Alessia Remigante, Bruno Burlando
    13-01-2021
    https://doi.org/10.4081/jbr.2020.9136
    773
    Downloads: 523
  • 084 | Modulation of the autophagic process by S1P under hypoxia: dissecting the contribution of S1P1 and S1P5 receptors Beatrice Pranzo1, Marco Greco1, Luisa Rosato1, Rita Paroni2, Maria Rosaria Coscia3, Paola Italiani4, Giacomo Strapazzon5, Sara Ottolenghi2, Federico Maria Rubino2, Alessia Ametrano3, Michele Samaja2, Giulia Maria Lionetto6, Michele Maffia1 | 1Department of Experimental Medicine, University of Salento, Lecce, Italy; 2Department of Health Sciences, University of Milano, Italy; 3Institute of Biochemistry and Cell Biology, National Research Council of Italy, Naples, Italy; 4Institute for Biomedical Research and Innovation, National Research Council of Italy, Palermo, Italy; 5Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy; 6Department of Biological and Environmental Sciences and Technologies, Lecce, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15336
    49
  • Inhibition of the cytotoxicity of pelagia noctiluca Venom by lanthanum sulfate

    G.L. Mariottini, E. Giacco, L. Pane
    30-01-2010
    https://doi.org/10.4081/jbr.2010.4436
    934
    Downloads: 709
  • CTLA-4 expressed by human dendritic cells modulates thei cytokine secretion and induction of T cell proliferation

    S. Laurent, P. Carrega, D. Saverino, P. Piccioli, M. Camoriamo, A. Morabito, B. Dozin, V. Fontana, R. Simone, L. Mortara, M.C. Mingari, G. Ferlazzo, M.P. Pistillo
    31-01-2011
    https://doi.org/10.4081/jbr.2011.4651
    965
    Downloads: 684
  • CELL SPECIFIC METABOLOMIC AND FLUXOMIC RESPONSES TO POLYLACTIC ACID NANOPLASTICS EXPOSURE IN HUMAN INTESTINAL CELLS Martina LOMBARDI1,2,3, Raffaella D’AURIA1, Marianna MARINO1, Mariagerarda LULLO1, Erwin Pavel LAMPARELLI1, Federica MONTELLA1, Giovanna DELLA PORTA1,4, Andrea VIGGIANO1, Jacopo TROISI1,2,3,5, Antonietta SANTORO1,4 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno; 2Theoreo Srl, Montecorvino Pugliano (SA); 3European Institute of Metabolomics - Fondazione EIM, Baronissi (SA); 4Interdepartmental Observatory for Scientific Health Initiatives in Environmental Legislation and Disease Prevention, SHIELD, University of Salerno; 5Department of Chemistry and Biology, “A. Zambelli”, University of Salerno, Fisciano (SA), Italy

    16-10-2025
    https://doi.org/10.4081/jbr.2025.14559
    186
  • 117 | Modulation of DNA methylation patterns and heat shock proteins following exercise and probiotic supplementation A. Boatta1|2, G. Messina1, A. Pagliaro3, A. Alioto3, C. Rossi3, L. Paladino4, F. Rappa6, F. Naselli5, F. Cappello6, R. Barone6, P. Proia3 | 1Department of Human Sciences and Promotion of Quality of Life, San Raffaele Roma Open University, Roma, Italy; 2Institute for Biomedical Research and Innovation, CNR, Palermo, Italy; 3Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Sciences and Human Movement, University of Palermo, Palermo, Italy; 4Department of Theoretical and Applied Sciences DiSTA, eCampus University, Novedrate, Italy; 5Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy; 6Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Palermo, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15369
    68
  • 173 | Lab-on-chip (LOC) as a tool for parkinson disease diagnosis: preliminary evaluation of neuronal cell culture on LOC Rosanna Mallamaci1, Rosangela Cardone1, Lorenzo Guerra1, Maria Noemi Sgobba1, Marilena Ardone1, Antonio Ancona2, Annalisa Volpe2a, Stefania Caragnano2, Salvatore Petralia3, Adriana Trapani4 | 1Department of Biosciences, Biotechnologies and Environment, University of Bari “Aldo Moro”, Bari, Italy; 2Physics Department, Università degli Studi di Bari & Politecnico di Bari, Italy; 3Department of Drug and Health Sciences, University of Catania, Italy; 4Department of Pharmacy-Drug Sciences, University of Bari “Aldo Moro”, Bari, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15425
    82
  • Assessment of an in vitro model of human cells to evaluate the toxic and irritating potential of chemical compounds

    M. Catalano, C. Scanarotti, R. Sanguineti, S. Penco, P. Romano, A. Cadoni, M.A. Pronzato, A.M. Bassi
    30-01-2011
    https://doi.org/10.4081/jbr.2011.4481
    841
    Downloads: 609
  • IDENTIFICATION OF D. MELANOGASTER ENZYMES POTENTIALLY INVOLVED IN PENTACHLOROPHENOL DEGRADATION M. CASTALDO1,2, D.M. MONTI2, A. TESTA3, J. VONTAS4,5, D. TSAKIRELLI4,5, M.M. MONTI1, P.A. PEDATA1 | 1Institute for Sustainable Plant Protection (CNR-IPSP), Portici (NA), Italy; 2Department of Chemical Sciences, University of Naples “Federico II”, Naples, Italy; 3Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Caserta, Italy; 4Pesticide Science Lab, Agricultural University of Athens, Athens, Greece; 5Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Crete, Greece

    16-10-2025
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  • 072 | A standardized onion peel-derived bioactive ingredient attenuates palmitate-induced steatosis and oxidative stress in HepG2 cells Ilaria Di Gregorio1|2, Vincenzo Migliaccio2, Maria D’Elia1|3|4, Rita Celano1|3, Anna Lisa Piccinelli1|3, Luca Rastrelli1|3, Lillà Lionetti2|3 | 1Dept Pharmacy, University of Salerno, Salerno, Italy; 2Dept Chemistry and Biology “A Zambelli”, University of Salerno, Italy; 3National Biodiversity Future Center NBFC, Palermo, Italy; 4Dept Earth and Marine Sciences, University of Palermo, Italy.

    Società Italiana di Biologia Sperimentale
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    67
  • 102 | Polylactic acid nanoparticles as metabolically active entities: a metabolomics and fluxomics perspective Martina Lombardi1|2|3, Vera Abenante2|3, Alessio Trotta2|3, Erwin Pavel Lamparelli1, Federica Montella1, Giovanna Della Porta1, Andrea Viggiano1, Jacopo Troisi1|2|3|4, Antonietta Santoro1 | 1Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 2Theoreo Srl, Montecorvino Pugliano, Salerno, Italy; 3European Institute of Metabolomics - Fondazione EIM, Baronissi, Salerno, Italy; 4Department of Chemistry and Biology, “A Zambelli”, University of Salerno, Fisciano [SA], Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
    https://doi.org/10.4081/jbr.2026.15354
    52
  • 026 | Graphene oxide nanosystem for antisense miRNA-21 delivery in hepatocellular carcinoma Paola Trischitta1, Rosamaria Pennisi1, Maria Teresa Sciortino1, Marta Kutwin2 | 1Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 2Dep of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences, Warsaw, Poland.

    Società Italiana di Biologia Sperimentale
    31-03-2026
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    54
  • Tribulus terrestris fruit’s potential for synthesizing gold nanoparticles with remarkable biological prospects

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    27-01-2025
    https://doi.org/10.4081/jbr.2025.12674
    5817
    Downloads: 1298
  • 05 | ENGINEERED PARTICLES IN DRUG DELIVERY AND TISSUE ENGINEERING: IMPLICATIONS FOR PUBLIC HEALTH Anna Barbara Di Stefano1, Simona Di Leo1, Mara Franza2|3, Francesca Toia1|2|3 | 1BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; 2Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; 3Section of Plastic and Reconstructive Surgery, Department of DAI chirurgico, Azienda Policlinico Paolo Giaccone, Palermo, Italy

    Società Italiana di Biologia Sperimentale
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    114
    Downloads: 23
  • 114 | Mechanisms of antimony-induced intestinal injury under chronic low-dose exposure: evidence from Caco‑2 cells and protective role of cyanidin-3-o-glucoside Federica Lina Salamone1|2, Maria Sofia Molonia1, Santi Trischitta1, Antonella Saija1, Francesco Cimino1, Antonio Speciale1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 2Imbesi Foundation, Messina, Italy.

    Società Italiana di Biologia Sperimentale
    31-03-2026
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  • The venom and the toxicity of Pelagia noctiluca (Cnidaria: Scyphozoa). A review of three decades of research in Italian laboratories and future perspectives

    Rossana Morabito, Angela Marino, Giuseppina La Spada, Luigi Pane, Gian Luigi Mariottini
    28-12-2015
    https://doi.org/10.4081/jbr.2015.5372
    2927
    Downloads: 1188
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Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

is the official journal of the Società Italiana di Biologia Sperimentale and it is published online by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

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