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• 100 | Tracking polystyrene nanoplastics by raman microscopy reveals intestinal and retinal toxicity Valentina Iezzi¹, Roberta Maria Ferri¹, Annamaria Iannetta², Ludovica Sulcanese², Tommaso Silvestrini², Vanessa D’Altilia², Giovanni Angelozzi², Federico Perrella³, Carino Ferrante⁴, Giulia Fioravanti³, Monia Perugini², Elisabetta Benedetti¹ | ¹Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; ²Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Italy; ³Department of Physical and Chemical Sciences University of L’Aquila, Italy; ⁴CNR-SPIN, c/o department of Physical and Chemical Sciences University of L’Aquila, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15352

  61

• 171 | Development of a 3D ex vivo model of human intestinal organoids for the study of inflammatory bowel diseases Giulia Maria Giorgia Lo Piano¹, Massimo Biondo¹, Adelaide Carista¹, Domiziana Picone¹, Stefano Burgio^2|3, Alberto Fucarino⁴, Francesca Rappa¹, Alessandro Pitruzzella¹, Fabio Bucchieri¹ | ¹Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; ²Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy; ³Department of Medicine and Surgery, Kore University of Enna, Enna, Italy; ⁴Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Como, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15423

  55

• 106 | Health effects of noise pollution on juvenile crustaceans: behavioral and molecular responses in Procambarus clarkii Maria Ceraulo^1|2, Giuseppa Buscaino¹, Clarissa De Vita¹, Aiti Vizzini^2|3|*, Mirella Vazzana^2|3, Elena Papale¹, Vincenzo Arizza^2|3, Francesco Longo³, Francesco Paolo Faraone³, Manuela Mauro^2|3 | ¹Institute for the Study of Anthropogenic impacts and Sustainability in the marine environment, National Research Council of Italy, Torretta Granitola, Campobello di Mazara [TP], Italy; ²NBFC, National Biodiversity Future Center, Palermo, Italy; ³Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15358

  70

• 071 | Decoding eryptosis: human red blood cells response to xenobiotic-induced stress Marilena Briglia¹, Alice Foti¹, Fabio Allia¹, Rosalia Battaglia¹, Giuseppe Piccione², Alessandro Attanzio³, Caterina Faggio⁴, Roberta Malaguarnera¹, Adriana Carol Eleonora Graziano¹ | ¹Department of Medicine and Surgery, University of Enna “Kore”, Enna, Italy; ²Department of Veterinary Sciences, University of Messina, Messina, Italy; ³Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; ⁴Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15323

  81

• 158 | Tick-borne pathogens in wild ungulates from Sicily (southern Italy): molecular detection and characterization Valeria Blanda¹, Valeria Vaglica¹, Sergio Migliore¹, Ilenia Giacchino¹, Elisa Maria Petta¹, Federico Cangialosi¹, Rosario Adragna¹, Santina Di Bella¹, Francesca Gucciardi¹, Silvia Scibetta¹, Francesca Grippi¹, Annalisa Guercio¹, Ettore Napoli², Paola Galluzzo¹ | ¹Istituto Zooprofilattico Sperimentale della Sicilia, Palermo, Italy; ²Department of Veterinary Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15410

  70

• 032 | Natural exposure to Lactococcus garvieae in rainbow trout: evidence of susceptibility and clinical outcomes Annalisa Cotugno¹, Sara Glorio Patrucco¹, Giorgia Zicarelli¹, Silvia Colussi^1|2, Martina Gini¹, Pier Luigi Acutis¹, Giulia Milanese¹, Giulia Stilo¹, Caterina Faggio^3|4, Giuseppe Esposito¹, Paolo Pastorino¹, Marino Prearo¹ | ¹Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Turin, Italy; ²Department of Animal, Nutritional and Food Sciences, Università Cattolica del Sacro Cuore, Piacenza, Italy; ³Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ⁴Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15284

  87

• 012 | Anticancer activity of Orobanche crenata leaf extract in human colorectal cancer cell lines Floriana D’Angeli¹, Alfio Distefano², Laura Orlando², Elisa Gili³, Valentina Di Salvatore⁴, Simone Ronsisvalle⁴, Ivana Roberta Romano², Giuliana Mannino², Debora Lo Furno², Giovanni Giurdanella¹, Giovanni Li Volti², Carlo Genovese¹ | ¹Department of Medicine and Surgery, School of Medicine and Surgery, University of Enna "Kore", Enna, Italy; ²Department of Biomedical and Biotechnological Sciences, University of Catania, Italy; ³Department of Clinical and Experimental Medicine, "Regional Referral Center for Rare Lung Diseases", University, Hospital Policlinico "G. Rodolico-San Marco", University of Catania, Italy; ⁴Department of Health and Drug Sciences, University of Catania, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15264

  63

• 06 | FROM MACRO- TO MICROPLASTICS IN THE SOUTHERN TYRRHENIAN SEA: AN INTEGRATED ANALYSIS OF MONITORING, IMPACTS ON BIOTA, AND MITIGATION STRATEGIES Monique Mancuso^1|2, Francesca Fabrizi^1|3, Ilaria Guardamagna¹, Chiara Anastasia Bruno¹, Teresa Bottari^1|2 | ¹Istituto per le Risorse Biologiche e le Biotecnologie Marine (IRBIM) - CNR, Messina, Italy; ²National Biodiversity Future Center (NBFC), Palermo, Italy; ³Scuola Universitaria Superiore IUSS Pavia, Italy

  Società Italiana di Biologia Sperimentale

  20-04-2026

  https://doi.org/10.4081/jbr.2026.15575

  124

  Downloads: 36

• 031 | Hypoxia exposure influences the oxidative status of Mytilus galloprovincialis in a time-dependent manner Alessia Caferro¹, Mariacristina Filice¹, Giorgia Giurlanda¹, Maria Assunta Iovine¹, Alfonsina Gattuso¹, Federica Impellitteri², Caterina Faggio³, Maria Carmela Cerra¹, Sandra Imbrogno¹ | ¹ Department of Biology, Ecology, and Earth Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy; ² Department of Veterinary Sciences, University of Messina, Italy; ³ Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15283

  59

• 156 | Thinned apple polyphenols extract improves skin wound healing by regulating oxidant, angiogenic and fibrotic markers Regina Aparo¹, Ramona D’Amico², Rosalba Siracusa¹, Giancarlo Aldini³, Daniela Impellizzeri¹ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Department of Medicine and Surgery, “Kore” University of Enna, Italy; ³Department of Pharmaceutical Sciences DISFARM, Università degli Studi di Milano, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15408

  59

• 052 | Metabolic analysis of farm animal plasma by 1H-NMR: variation and preliminary spectral characterization Luca Cicero¹, Silvia Orecchio¹, Aldo Migliazzo¹, Valeria Vitale Badaco¹, Stefano Burgio³, Tiziana Orefice¹, Giuseppe La Corte¹, Antonino La Corte¹, Grazia Scuderi², Paolo Fagone², Giovanni Cassata¹ | ¹Istituto Zooprofilattico Sperimentale della Sicilia, Italy; ²Università degli Studi di Catania, Italy; ³Università di Enna "Kore", Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15304

  47

• 176 | Preliminary observations on cannabinoid receptor activation in an in vitro steatosis model and in triple-negative breast cancer cells Roberta Oliveri¹, Gianluca Lavanco², Giovanni Pratelli¹, Diana Di Liberto¹, Fabiana Plescia³, Anna De Blasio³, Francesca Vaccaro², Stella Cascioferro³, Flavia Zingales¹, Marianna Lauricella¹, Rosaria Maria Pipitone², Stefania Grimaudo², Fulvio Plescia², Daniela Carlisi¹ | ¹Department of Biomedicine, Neurosciences and Advanced Diagnostics BiND, University of Palermo, Italy; ²Department of Health Promotion Sciences, Maternal and Child Care, Internal Medicine and Medical Specialties “Giuseppe D'Alessandro”, University of Palermo, Italy; ³Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF - University of Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15428

  83

• 143 | Anodal tDCS enhances decision precision during biological motion perception: a computational active inference perspective Antonio Cangelosi¹, Umberto Quartetti¹, Giulio Musotto², Dimitri Ognibene³, Giuditta Gambino¹, Giuseppe Giglia¹ | ¹Department of Biomedicine, Neuroscience and Advanced Diagnostics BiND, Section of Human Physiology, University of Palermo, Italy; ²Bioengineering Unit, RiMED Foundation, Palermo, Italy; ³Department of Psychology, University of Milan-Bicocca, Milan, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15395

  83

• 162 | Functional and health-promoting properties of EVOO from Sicilian olive cultivars: focus on oxidative stress and inflammation Mariateresa Cristani¹, Ali Mert Yetisgin², Giovanni Bartolomeo³, Nicola Cicero^3|4, Rosaria Costa³, Nicola Micale¹ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy; ²İnönü University, Faculty of Pharmacy, Kampüs, Battalgazi/Malatya, Türkiye; ³Department of Biomedical, Dental, Morphological and Functional Images Sciences BIOMORF, University of Messina, Messina, Italy; ⁴Science4Life srl, start-up of the University of Messina, Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15414

  105

• 130 | Behavioural taxonomy of the common octopus: a framework for understanding individual variation through complex task navigation Emanuela Cirillo^1|2, Tania Russo³, Mariangela Norcia¹, Valeria Maselli¹, Salvatore Valiante¹, Michael Kuba¹, Marco Gamba⁴, Gianluca Polese^1|2, Anna Di Cosmo^1|2 | ¹Dipartimento di Biologia, Università di Napoli Federico II, Napoli, Italy; ²MNESYS - PNRR partenariato esteso; ³Dipartimento di Biologia, Ecologia e Scienze della Terra, Università della Calabria, Rende (CS), Italy; ⁴Dipartimento di Scienze della Vita e Biologia dei Sistemi, Università di Torino, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15382

  80

• 024 | In vitro analysis of molecular chaperone involvement in the radiological response of triple-negative breast cancer models Giusi Alberti¹, Giuseppe Vergilio¹, Domiziana Picone¹, Denise Amico¹, Rosario Barone¹, Francesca Rappa¹, Marco Calvaruso³, Gaia Pucci³, Luigi Minafra³, Antonella Marino Gammazza² | ¹Department of Biomedicine, Neuroscience and Advanced Diagnostic BIND, University of Palermo, Italy; ²Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; ³Institute of Bioimaging and Complex Biological Systems-National Reasearch Council IBSBC-CNR, Cefalù-Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15276

  64

• 044 | Thyroid response to stress in illness Caretta caretta: a preliminary study Chiara Lomonaco¹, Paola Galluzzo^2|3, Giorgia Schirò^1|3, Angelo Costanza^2|3, Rosario Adragna³, Vincenzo Monteverde^2|3, Claudia Giannetto¹, Salvatore Dara^2|3, Rosaria Disclafani^2|4 | ¹Dipartimento di Scienze Veterinarie, Polo Universitario dell’Annunziata, University of Messina, Italy; ²Centro Referenza Nazionale per il Benessere, Monitoraggio e Diagnostica delle malattie delle Tartarughe Marine CReTaM; ³Istituto Zooprofilattico Sperimentale della Sicilia “A. Mirri”, Palermo, Italy; ⁴Centro di Sostenibilità e Transizione Ecologica, University of Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15296

  57

• 05 | ENGINEERED PARTICLES IN DRUG DELIVERY AND TISSUE ENGINEERING: IMPLICATIONS FOR PUBLIC HEALTH Anna Barbara Di Stefano¹, Simona Di Leo¹, Mara Franza^2|3, Francesca Toia^1|2|3 | ¹BIOPLAST-Laboratory of BIOlogy and Regenerative Medicine-PLASTic Surgery, Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; ²Plastic and Reconstructive Surgery Section, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Italy; ³Section of Plastic and Reconstructive Surgery, Department of DAI chirurgico, Azienda Policlinico Paolo Giaccone, Palermo, Italy

  Società Italiana di Biologia Sperimentale

  20-04-2026

  https://doi.org/10.4081/jbr.2026.15574

  138

  Downloads: 37

• 103 | Valorization of olive mill wastewaters for the recovery of polyphenols with reducing, radical scavenging and anti-inflammatory activities Francesco Longo¹, Luisa Tesoriere¹, Claudio Luparello¹, Ignazio Restivo¹, Federica Bellistrì¹, Serena Indelicato¹, David Bongiorno¹, Rosi De Luca¹, Giulia Abruscato¹, Antonio Fabbrizio², Salvatore Terrani³, Mirella Vazzana¹, Vincenzo Arizza¹, Manuela Mauro¹ | ¹Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; ²Department of Theoretical and Applied Sciences DiSTA, University e Campus, Novedrate [CIO], Italy; ³The Wave Innovation Group, Verona, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15355

  74

• COMBINED EFFECTS OF POLYSTYRENE MICROPLASTICS, NANOPLASTICS, AND MERCURY ON THE GILL STRUCTURE AND FUNCTION OF MYTILUS GALLOPROVINCIALIS Rossana ROMANO^1,2, Maria D. BORDALO³, Hugo C. VIEIRA³, Sílvia FS. PIRES³, Federica DI FRANCO¹, Chiara M. MOTTA⁴, Palma SIMONIELLO^1,2 | ¹Department of Science and Technology, University Parthenope, Napoli, Italy; ²International PhD Programme, UNESCO Chair “Environment, Resources and Sustainable Development”, Department of Science and Technology, Parthenope University of Naples, Naples, Italy; ³CESAM—Centre for Environmental and Marine Studies, Department of Biology, University of Aveiro, Aveiro, Portugal; ⁴Department of Biology, University of Naples Federico II, Napoli, Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14547

  185

• 088 | Investigating the role of Hsp60 in the pathophysiology of celiac disease Giusy Vultaggio¹, Giuseppe Vergilio^1|2, Letizia Paladino³, Rosario Barone¹, Francesca Rappa¹ | ¹Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; ²Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy; ³Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15340

  62

• EFFECTS OF POLYLACTIC ACID-NANOPLASTICS ON THE INTESTINAL BARRIER: IN VITRO ANALYSIS ON HUMAN EPITHELIAL CELLS Maria Gerarda LULLO¹, Raffaella D’AURIA¹, Marianna MARINO¹, Martina LOMBARDI¹, Giovanna DELLA PORTA^1,2, Erwin Pavel LAMPARELLI¹, Rosaria MECCARIELLO³, Andrea VIGGIANO^1,2, Antonietta SANTORO^1,2 | ¹Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Fisciano, Salerno, Italy; ²Interdepartmental Observatory for Scientific Health Initiatives in Environmental Legislation and Disease Prevention, SHIELD, University of Salerno, Italy; ³Department of Medical, Motor and Wellness Sciences, University of Naples Parthenope, Naples, Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14560

  228

• 142 | Drug repositioning reveals novel therapeutic candidates for spinal muscular atrophy Marina Boido¹, Daniela Maria Rasà¹, Serena Stanga¹, Ersilia Nicorvo¹, Pamela Santonicola², Nadia Mazzarella³, Antonella Camera², Roberto Iacomino², Ilenia Matino², Silvia Chasseur¹, Giuseppina Zampi², Piera Smeriglio⁴, Elia Di Schiavi², Alessandro Vercelli¹ | ¹Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy; ²Institute of Biosciences and BioResources ^IBBR, National Research Council CNR, Naples, Italy; ³Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" IGB-ABT, National Research Council CNR, Naples, Italy; ⁴Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15394

  45

• 091 | Increased vulnerability to experimental colitis following chronic low-dose exposure to Sicilian environmental contaminants Noemi Aloi^1|2, Paolo Colombo², Valeria Longo², Rosa Serio¹, Maria Grazia Zizzo¹ | ¹Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, Università di Palermo, Italy; ²Institute for Biomedical Research and Innovation, National Research Council of Italy IRIB-CNR, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15343

  55

• 097 | Pharmaceutical pollution in aquatic environments: effects of valsartan on Mytilus galloprovincialis Giorgia Giurlanda¹, Alessia Caferro¹, Mariacristina Filice¹, Maria Assunta Iovine¹, Alfonsina Gattuso¹, Federica Impellitteri², Caterina Faggio³, Maria Carmela Cerra¹, Sandra Imbrogno¹ | ¹Department of Biology, Ecology, and Earth Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy; ²Department of Veterinary Sciences, University of Messina, Italy; ³Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15349

  57

• 060 | Interdomain interactions and pH modulate folding intermediates in MAGI1 PDZ4 Cosmin Marian Obreja¹, Valeria Pennacchietti², Dimitrios Marinidis¹, Sara Di Matteo³, Rodolfo Ippoliti¹, Stefano Gianni², Francesca Malagrinò¹ | ¹University of L’Aquila, Italy; ²University “La Sapienza” of Rome, Italy; ³University of Chieti-Pescara, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15312

  49

• 023 | Chaperone-associated macrophage polarization and extracellular matrix remodelling in human glioblastoma Leila Noori^1|2, Rosario Barone¹, Giuseppe Vergilio^1|2, Maria Antonella Augello¹, Giuseppa D’Amico¹, Federica Scalia³, Pierlorenzo Veiceschi², Giovanni Tringali², Francesco Cappello¹, Celeste Caruso Bavisotto¹ | ¹Department of Biomedicine, Neuroscience and Advanced Diagnostics [BiND], University of Palermo, Italy; ²Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS, Palermo, Italy; ³Department of Medicine and Surgery, Kore University of Enna, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15275

  73

• 116 | Exosomes and miRNA content engagement in inflammatory processes let's take stock in the veterinary field Francesca Arfuso¹, Jessica M. Abbate², Claudia Giannetto¹, Marilena Briglia³, Elisabetta Giudice¹, Giovanni Lanteri², Giuseppe Piccione¹ | ¹Department of Veterinary Sciences, University of Messina, Polo Universitario Annunziata, Messina, Italy; ²Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, Polo Universitario Papardo, Messina, Italy; ³Department of Medicine and Surgery “Kore”, University of Enna, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15368

  58

• INNOVATIVE MULTI-OMIC STRATEGIES TO EXPLORE MICRO- AND NANOPLASTIC EFFECTS Andrea INGENITO^1,2, Nicole PALMIERI^1,2,3, Alessio TROTTA^1,2, Vera ABENANTE^1,2, Jacopo TROISI^1,2,4 | ¹Theoreo srl, Montecorvino Pugliano, SA, Italy; ²European Institute of Metabolomics - Fondazione EIM, Baronissi (SA) Italy; ³Department of Chemistry and Biology, “A. Zambelli”, University of Salerno, Fisciano (SA); ⁴Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Baronissi (SA), Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14568

  199

• 066 | Modulation of oxidative stress and mitochondrial alteration in IL1β-stimulated human astrocytes: effects of extracts from leaves and rhizomes of Posidonia oceanica (L) Delile Giulia Abruscato¹, Lucia Sileo², Giulia Scanavino², Manuela Mauro¹, Francesco Longo¹, Vincenzo Arizza^1|3, Mirella Vazzana^1|3, Claudio Luparello^1|3, Ada Maria Tata² | ¹Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STeBICeF, University of Palermo, Italy; ²Department of Biology and Biotechnologies Charles Darwin, Sapienza- University of Rome, Italy; ³National Biodiversity Future Center NBFC, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15318

  56

• 189 | Fluorescent analysis by confocal microscopy of lipid droplets as a marker of oocyte quality in Sarda sheep under different seasonal conditions Silvia Zaccardi¹, Domenica Cocciolone¹, Guido Macchiarelli¹, Sara Succu², Giovanni Giuseppe Leoni³, Maria Grazia Palmerini¹ | ¹Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; ²Department of Veterinary Medicine, University of Sassari, Italy; ³Department of Biomedical Sciences, University of Sassari, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15441

  79

• 087 | Synergistic collapse of redox homeostasis in human hepatic and renal cells: perfluorooctane sulfonate as a priming factor for oxidative pathophysiology Graziano Vinci¹, Marika Cordaro², Rosanna Di Paola³ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Italy; ²Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy; ³Department of Veterinary Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15339

  54

• 141 | An inverted taxonomic approach unveils diversity of cladophoraceae (Chlorophyta) in two nature oriented reserves in northern Sicily (Italy) Matteo Vita¹, Vincenzo Zammuto¹, Mattia Soppelsa¹, Fabio Mondello¹, Salvatore Giacobbe², Marina Morabito¹, Antonio Manghisi¹ | ¹Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²CNR-IRBIM, Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15393

  66

• 036 | Diversity and composition of microbial communities associated with deep-sea marine litter Vittoria Dias^1|2, Carmen Rizzo^1|3, Cristina Pedà¹, Pierpaolo Consoli¹, Teresa Romeo^1|3 | ¹Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; ²University of Milano Bicocca, Milano, Italy; ³National Biodiversity Future Centre NBFC, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15288

  72

• 079 | Pharmacological modulation of the STING pathway as an antiviral strategy against HSV-1 Federica Mastrolembo Barnà^1|2, Paola Trischitta^1|2, Marianna Costa^1|2, Antonella Torre³, Alessia Onali³, Angela Pagliaro³, Alberto Deplano³, Elias Maccioni³, Rita Meleddu³, Simona Distinto³, Rosamaria Pennisi¹, Maria Teresa Sciortino¹ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Dep of chemistry, biology and biotechnology, University of Perugia, Italy; ³Department of Life and Environmental Sciences, Section of Drug Sciences, University of Cagliari, University Campus, Monserrato [CA], Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15331

  68

• 028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale¹, Giuseppa D’Amico¹, Martina Di Marco¹, Giuseppina Poppa², Pierlorenzo Maria Veiceschi³, Alessandro Lo Giudice¹, Francesca Chiara Cecala¹, Paola Limoncelli², Ilaria Giusti², Vincenza Dolo², Claudia Campanella¹, Francesca Rappa¹, Rosario Barone¹, Giovanni Tringali³, Francesco Cappello¹, Celeste Caruso Bavisotto¹ | ¹Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; ²Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; ³Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15280

  59

• 121 | Probiotics effect on brain-gut axis mediated by nanovescicles Alessandro Lo Giudice¹, Giuseppa D’Amico¹, Melania Ionelia Gratie¹, Letizia Paladino², Giusy Vultaggio¹, Adelaide Carista¹, Francesco Cappello¹, Vita Di Stefano³, Celeste Caruso Bavisotto¹ | ¹Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; ²Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy; ³Department of Biological, Chemical, and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15373

  47

• 172 | Genetic diversity of Candida albicans in animal hosts Lucilla Lo Re¹, Letterio Giuffrè¹, Silvia Crotti², Deborah Cruciani², Alice Ranucci², Orazio Romeo¹ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Experimental Zooprophylactic Institute of Umbria and Marche “Togo Rosati”, Perugia, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15424

  77

• 034 | Characterization of a ribavirin-based drug delivery system against viral nervous necrosis virus Marianna Costa^1|2, Rosamaria Pennisi¹, Paola Trischitta¹, Federica Mastrolembo Barnà^1|2, Giuseppe Nocito³, Antonino Mazzaglia³, Maria Teresa Sciortino¹ | ¹Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy; ³CNR-ISMN URT of Messina at Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15286

  55

• DEVELOPMENT OF A NOVEL PROTOCOL FOR THE EXTRACTION OF SMALL MICROPLASTICS (1-5 µm) FROM BIOLOGICAL TISSUES Mary Carolin KURISINGAL CLEETUS¹, Ludovico PONTONI², Luigi ROSATI³, Massimiliano FABBRICINO², Annamaria LOCASCIO¹ | ¹Department of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Naples, Italy; ²Department of Civil, Architectural and Environmental Engineering, University of Naples Federico II, Naples, Italy; ³Department of Biology, University of Naples Federico II, Monte Sant’Angelo, Naples, Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14540

  220

• 111 | Plastic contamination in bycaught yelkouan shearwater (Puffinus yelkouan) from the Mediterranean sea Marco Parolini¹, Federico Tossani¹, Federico De Pascalis², Dimitra Christidi³, Angelos Evangelidis³, Andrea Benvenuti⁴, Sara Di Leo¹, Simona Mondellini¹, Giacomo Dell’Omo⁴, Danae Portolou³, Jacopo G. Cecere², Diego Rubolini¹ | ¹Department of Environmental Science and Policy, University of Milan, Italy; ²Area Avifauna Migratrice, Istituto Superiore per la Protezione e la Ricerca Ambientale ISPRA, Ozzano dell’Emilia, Italy; ³Hellenic Ornithological Society, Athens, Greece; ⁴Animal Tracking, TECHNOSMART EUROPE srl, Guidonia-Montecelio, Roma, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15363

  68

• 159 | Innovative and sustainable strategies to recover bioactive molecules from pruning waste Giovanna Cafeo¹, Marina Russo¹, Alessia Arena², Mariosimone Zoccali³, Paola Dugo^1|2, Luigi Mondello^1|2 | ¹Messina Institute of Technology, c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Chromaleont srl, c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ³Department of Mathematical and Computer Science, Physical Sciences and Earth Sciences, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15411

  67

• EVALUATING ENDOCRINE AND OXIDATIVE EFFECTS OF POLYLACTIC ACID NANOPLASTICS (PLA-NPs) ON BREAST CELL MODELS Maria Denise AMICO¹, Antonietta SANTORO², Erwin Pavel LAMPARELLI², Giovanna DELLA PORTA², Magdalena GORSKA-PONIKOWSKA^3,4,5, Francesca RAPPA^1,5, Fabio BUCCHIERI¹, Francesco CAPPELLO^1,5 | ¹Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; ²Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; ³Department of Medical Chemistry, Medical University of Gdansk, Poland; ⁴Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Germany; ⁵Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14556

  214

• 180 | Shared pathways in experimental projects: research, territory, and scientific communities compared the example of the initiatives of the Regional Agency for Rural Development – Ersa (Friuli Venezia Giulia, Italy) Simona Rainis | Regional Agency for the Rural Development ERSA, Gorizia, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15432

  52

• PERINATAL EXPOSURE TO BISPHENOL A AND BISPHENOL B CAN ALTER THE SEXUAL BEHAVIOUR AND REPRODUCTIVE SYSTEM OF OFFSPRING Elena RICCI^1,2, Marilena MARRAUDINO^1,2, Noemi CADORIN¹, Iva SABOVIC³, Alberto FERLIN³, Stefano GOTTI^1,2 | ¹Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Torino, Italy; ²Department of Neuroscience ‘Rita Levi Montalcini’, University of Torino, Torino, Italy; ³Department of Medicine, Operative Unit of Andrology and Medicine of Human Reproduction, University of Padova, Padova, Italy

  16-10-2025

  https://doi.org/10.4081/jbr.2025.14563

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• 070 | Role of bioactive extracts obtained from marine sources and agri-food industry by-products in ETosis modulation Federica Bellistrì¹, Giulia Abruscato¹, Manuela Perlotti¹, Alessia Lo Muzzo¹, Claudio Gargano¹, Francesco Longo¹, Manuela Mauro¹, Roberto Chiarelli¹, Vincenzo Arizza^1|3, Claudio Luparello^1|3, Gianluca Sarà^2|3, Mirella Vazzana^1|3 | ¹Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; ²Department of Earth and Marine Sciences, Palermo, Italy; ³National Biodiversity Future Center, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15322

  66

• 094 | 2-octyl-2h-isothiazol-3-one and its role in zebrafish larvae neurogenesis and neuronal function Vanessa D’Altilia¹, Ludovica Sulcanese¹, Valentina Iezzi², Silvana Zugaro², Annamaria Iannetta¹, Tommaso Silvestrini^1|3, Elisabetta Benedetti², Monia Perugini¹. | ¹Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Teramo, Italy; ²Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy; ³University of Camerino, International School of Advanced Studies, Camerino, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15346

  66

• 020 | A three-dimensional vascularized cancer model mimicking the tumor microenvironment for drug resistance studies Alessandra Lo Cicero¹, Gabriele Lo Buglio¹, Francesco La Monica¹, Simona Campora¹, Margot Lo Pinto², Simone Dario Scilabra², Giulio Ghersi^1|3 | ¹Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Palermo, Italy; ²Proteomics Group of RiMED Foundation, Research Department IRCCS ISMETT Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy; ³Abiel srl, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15272

  61

• 179 | Body fat reduction in adult women: a longitudinal study after six-month Bikram yoga Federico Zoila^1|2, Francesca Martina Filannino¹, Maria Ida De Stefano¹, Pasquale Simeone¹, Daniela Cagnetta¹, Antonia Cianciulli³, Melania Ruggiero³, Maria Antonietta Panaro³, Chiara Porro¹ | ¹Department of Clinical and Experimental Medicine, University of Foggia, Italy; ²Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy; ³Department of Biosciences, Biotechnologies and Environment, University of Bari, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15431

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• 007 | Dysregulation of the trans-sulfuration-sphingosine-1-phosphate signaling axis in glioblastoma: preclinical evidence Elsa Calcaterra¹, Michela Campolo¹, Melania Correale², Rossella Basilotta¹, Maria Caffo³, Roberta D’Emmanuele Di Villa Bianca², Emma Mitidieri², Giovanna Casili¹, Emanuela Esposito¹ | ¹Department of Chemical, Biological, Pharmaceutical, Environmental Sciences, University of Messina, Italy; ²Department of Pharmacy, School of Medicine and Surgery, University of Study of Naples - Federico II, Naples, Italy; ³Unit of Neurosurgery, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15259

  66