A narrative review on palliative care in the emergency department: dealing with the uncertainty of death


Submitted: 13 March 2023
Accepted: 16 May 2023
Published: 23 June 2023
Abstract Views: 1355
PDF: 308
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

In the last decades emergency physicians have observed a steep increase in the emergency department (ED) admissions of palliative care patients who rely on the hospital for symptoms’ relief and management of acute exacerbations of their chronic disease. Previous studies have suggested that palliative care interventions in the ED could prevent unnecessary admissions and reduce both the length of hospitalization and costs. However, emergency medicine physicians might have limited specialistic education and resources to provide a correct management of palliative care patients and avoid futile interventions. Thus, we aim in this narrative review to provide the reader with an introduction on the principles that should guide the emergency physician in a correct approach to palliative care patients in the ED. We will explain how to deal with the intrinsic prognostic uncertainty of palliative care patients by implementing a correct ethical approach which encompasses the understanding of both appropriateness and futility of intervention; furthermore, we will present practical tools such as scores and trials.


UN Department of Economic and Social Affairs, Population Division: World Population Ageing 2013. UN, 2013.

WHO’s Global Health Estimates (GHE) World Health Organization. 2019. Available from: https://www.who.int/data/global-health-estimates

Kardamanidis K, Lim K, Da Cunha C, et al. Hospital costs of older people in New South Wales in the last year of life. Med J Aust 2007;187:383–6. DOI: https://doi.org/10.5694/j.1326-5377.2007.tb01306.x

Smith AK, McCarthy E, Weber E, et al. Half of older Americans seen in emergency department in last month of life; most admitted to hospital, and many die there. Health Aff (Millwood) 2012;31:1277-85. DOI: https://doi.org/10.1377/hlthaff.2011.0922

Da Silva Soares D, Nunes CM, Gomes B. Effectiveness of emergency department based palliative care for adults with advanced disease: a systematic review. J Palliat Med 2016;19:601-9. DOI: https://doi.org/10.1089/jpm.2015.0369

Cervellin G, Casagranda I, Ricci G, et al. Unavoidable deaths in the Italian Emergency Departments. Results of a ten-year survey. A mirror of substantial social changes, or a warning for a hospital-system pathology? Emerg Care J 2017;13:6718. DOI: https://doi.org/10.4081/ecj.2017.6718

Elmer J, Mikati N, Arnold RM, et al. Death and End-of-Life Care in Emergency Departments in the US. JAMA Netw Open 2022;5:e2240399. DOI: https://doi.org/10.1001/jamanetworkopen.2022.40399

Wang DH, Breyre AM, Brooten JK, Hanson KC. Top ten tips palliative care clinicians should know about improving partnerships with emergency medical services. J Palliat Med 2023;26:704-10. DOI: https://doi.org/10.1089/jpm.2022.0537

Bowman JK, Aaronson EL, Petrillo LA, Jacobsen JC. Goals of care conversations documented by an embedded emergency department-palliative care team during COVID. J Palliat Med 2023;26:662-6. DOI: https://doi.org/10.1089/jpm.2022.0314

European Society For Medical Oncology. Available from: https://www.esmo.org/covid-19-and-cancer/covid-19-resource-centre/covid-19-palliative-care-pathways

Grudzen CR, Stone SC, Morrison RS. The palliative care model for emergency department patients with advanced illness. J Palliat Med 2011;14:945–50. DOI: https://doi.org/10.1089/jpm.2011.0011

Stone SC, Mohanty S, Grudzen CR, et al. Emergency medicine physicians' perspectives of providing palliative care in an emergency department. J Palliat Med 2011;14:1333–8. DOI: https://doi.org/10.1089/jpm.2011.0106

Smith AK, Fisher J, Schonberg MA, et al. Am I doing the right thing? Provider perspectives on improving palliative care in the emergency department. Ann Emerg Med 2009;54:86–93.e1 DOI: https://doi.org/10.1016/j.annemergmed.2008.08.022

O'Connor AE, Winch S, Lukin W, Parker M: Emergency medicine and futile care: Taking the road less travelled. Emerg Med Australas 2011;23:640–3. DOI: https://doi.org/10.1111/j.1742-6723.2011.01435.x

Poggiali E, Bertè R, Orsi L. When emergency medicine embraces palliative care. Emerg Care J 2022;18:11013. DOI: https://doi.org/10.4081/ecj.2022.11013

Downie RS, Macnaughton J. Clinical judgement: evidence in practice. Oxford, Oxford University Press, 2000.

Macnaughton J The humanities in medical education: context, outcomes and structures Medical Humanities 2000;26:23-30. DOI: https://doi.org/10.1136/mh.26.1.23

Orsi L, Gristina GR. The right choice at the right time Minerva Anestesiologica 2017;83:436-9. DOI: https://doi.org/10.23736/S0375-9393.17.11940-1

Beller EM, Driel ML van, McGregor L, et al. Palliative pharmacological sedation for terminally ill adults. Cochrane Database of Systematic Reviews 2018. DOI: https://doi.org/10.1002/14651858.CD010206.pub2

De Iaco F, Gandolfo E, Guarino M, et al. Terapia del dolore in Urgenza e Sedazione Procedurale. Amazon self publishing. Chapter 14. 2022.

Società italiana Cure Palliative (SICP). https://www.sicp.it/aggiornamento/linee-guida-bp-procedures/2022/06/sala-del-sollievo-e-sedazione-palliativa-malato-end-stage-con-sintomi-refrattari-nel-dea/

Murray SA, Kendall M, Boyd K, Sheikh A. Illness trajectories and palliative care. BMJ 2005;330:1007-11. DOI: https://doi.org/10.1136/bmj.330.7498.1007

Beauchamp TL, Childress JF. Principles of biomedical ethics. New York: Oxford University Press; 2001.

American College of Emergency Physicians. Code of ethics for emergency physicians. Accessed March 8, 2023. Available from: https://www.acep.org/globalassets/sites/acep/media/by-medical-focus/ethics/code-of-ethics-for-emergency-physicians.pdf

Vergano M, Magavern E, Zamperetti N. Clinical ethics: what the anesthesiologist and the intensivist need to know. Minerva Anestesiol 2018;84:515-22. DOI: https://doi.org/10.23736/S0375-9393.17.12055-9

Hinshaw DB, Pawlik T, Mosenthal AC, et al. When do we stop, and how do we do it? Medical futility and withdrawal of care. J Am Coll Surg 2003;196:621-51. DOI: https://doi.org/10.1016/S1072-7515(03)00106-6

Moss A, Ganjoo J, Sharma S, et al. Utility of the “surprise” question to identify dialysis patients with high mortality. Clin J Am Soc of Nephrol 2008;3:1379-84. DOI: https://doi.org/10.2215/CJN.00940208

Moss A, Lunney JR, Culp S, et al. Prognostic significance of the “surprise” question in cancer patients. J Palliat Med 2010;13:837-840. DOI: https://doi.org/10.1089/jpm.2010.0018

Haydar S, Almeder L, Michalakes L, et al. Using the surprise question to identify those with unmet palliative care needs in emergency and inpatient settings: what do clinicians think? J Palliat Med 2017;20:729-35. DOI: https://doi.org/10.1089/jpm.2016.0403

Mitchell G, Senior HE, Rhee JJ, et al. Using intuition or a formal palliative care needs assessment screening process in general practice to predict death within 12 months: a randomised controlled trial. Palliat Med 2018;32:384-94. DOI: https://doi.org/10.1177/0269216317698621

Zeng H, Eugene P, Supino M. Would you be surprised if this patient died in the next 12 months? Using the surprise question to increase palliative care consults from the emergency department. J Palliat Care 2020;35:221-5. DOI: https://doi.org/10.1177/0825859719866698

Babcock M, Gould Kuntz J, Kowalsky D, et al. The palliative performance scale predicts three- and six-month survival in older adult patients admitted to the hospital through the emergency department. J Palliat Med 2016;19:1087-91. DOI: https://doi.org/10.1089/jpm.2016.0011

Harrold J, Rickerson E, Carroll JT, et al. Is the palliative performance scale a useful predictor of mortality in a heterogeneous hospice population? J Palliat Med 2005;8:503–9. DOI: https://doi.org/10.1089/jpm.2005.8.503

Head B, Ritchie CS, Smoot TM. Prognostication in hospice care: Can the palliative performance scale help? J Palliat Med 2005;8:492–502. DOI: https://doi.org/10.1089/jpm.2005.8.492

Morita T, Tsunoda J, Inoue S, Chihara S. Validity of the palliative performance scale from a survival perspective. J Pain Symptom Manage 1999;18:2–3. DOI: https://doi.org/10.1016/S0885-3924(99)00096-2

Downing M, Lau F, Lesperance M, et al. Meta-analysis of survival prediction with palliative performance scale. J Palliat Care 2007;23:245–252; discussion 252–254. DOI: https://doi.org/10.1177/082585970702300402

Paske JRT, DeWitt S, Hicks R, et al. Palliative care and rapid emergency screening tool and the palliative performance scale to predict survival of older adults admitted to the hospital from the emergency department. Am J Hosp Palliat Care 2021;38:800-6. DOI: https://doi.org/10.1177/1049909120960713

Bowman J, George N, Barrett N, et al. Acceptability and reliability of a novel palliative care screening tool among emergency department providers. Acad Emerg Med 2016;23:694-702. DOI: https://doi.org/10.1111/acem.12963

Tan A, Durbin M, Chung FR, et al. Design and implementation of a clinical decision support tool for primary palliative Care for Emergency Medicine (PRIM-ER). BMC Med Inform Decis Mak 2020;20:13. DOI: https://doi.org/10.1186/s12911-020-1021-7

Calsina-Berna A, Amblàs Novellas J, González-Barboteo J, et al. Prevalence and clinical characteristics of patients with Advanced Chronic Illness and Palliative Care needs, identified with the NECPAL CCOMS-ICO© Tool at a Tertiary Care Hospital. BMC Palliat Care 2022;21:210. DOI: https://doi.org/10.1186/s12904-022-01101-4

Gómez-Batiste X, Martínez-Muñoz M, Blay C, et al. Utility of the NECPAL CCOMS-ICO© tool and the Surprise Question as screening tools for early palliative care and to predict mortality in patients with advanced chronic conditions: A cohort study. Palliat Med 2017;31:754-63. DOI: https://doi.org/10.1177/0269216316676647

VanKerkhoff TD, Viglianti EM, Detsky ME, Kruser JM. Time-limited trials in the intensive care unit to promote goal-concordant patient care. Clin Pulm Med 2019;26:141-5. DOI: https://doi.org/10.1097/CPM.0000000000000323

Temel JS, Greer JA, Muzikansky A, et al. Early palliative care for patients with metastatic non–small-cell lung cancer. N Engl J Med 2010;363:733-42 DOI: https://doi.org/10.1056/NEJMoa1000678

Bozzaro C, Schildmann J. "Suffering" in palliative sedation: conceptual analysis and implications for decision making in clinical practice. J Pain Symptom Manage 2018;56:288-94. DOI: https://doi.org/10.1016/j.jpainsymman.2018.04.003

Prado BL, Gomes DBD, Usón Júnior PLS, et al. Continuous palliative sedation for patients with advanced cancer at a tertiary care cancer center. BMC Palliat Care 2018;17:13. DOI: https://doi.org/10.1186/s12904-017-0264-2

Imai K, Morita T, Mori M, et al. Family experience of palliative sedation therapy: proportional vs. continuous deep sedation. Support Care Cancer 2022;30:3903-15. DOI: https://doi.org/10.1007/s00520-021-06745-1

De Araujo C, De Araújo L, Nassar Junior A. Palliative sedation in patients with advanced cancer in a specialized unit in a middle-income country: A retrospective cohort study. Palliative & Supportive Care 2022;20:491-5. DOI: https://doi.org/10.1017/S1478951521001371

Arantzamendi M, Belar A, Payne S, et al. Clinical aspects of palliative sedation in prospective studies. A systematic review. J Pain Symptom Manage 2021;61:831-844.e10. DOI: https://doi.org/10.1016/j.jpainsymman.2020.09.022

Olsen ML, Swetz KM, Mueller PS. Ethical decision making with end-of-life care: palliative sedation and withholding or withdrawing life-sustaining treatments. Mayo Clin Proc 2010;85:949-54. DOI: https://doi.org/10.4065/mcp.2010.0201

Porta, L., & Mauri, E. (2023). A narrative review on palliative care in the emergency department: dealing with the uncertainty of death. Emergency Care Journal, 19(2). https://doi.org/10.4081/ecj.2023.11308

Downloads

Download data is not yet available.

Citations