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46 | Investigating the impact of the tumor secretome on in vitro human skeletal and cardiac muscle models of cancer-induced cachexia Ashley Ju-Wei Wang1, L. Yedigaryan 1|2, M. Campaner Socias1, J. Zhang1, F. Palmieri3, L. Rinvenuto1, V. Marini1, R. Squecco3, M. Seelaender4, M. Sampaolesi1|5 | 1Laboratory of Translational Cardiomyology, Stem Cell Institute Leuven, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Inserm U1258, CNRS UMR7104, Université de Strasbourg, Illkirch, France; 3Department of Experimental and Clinical Medicine, Section of Physiological Sciences, University of Florence, Florence, Italy; 4Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo, São Paulo SP, Brazil; 5Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy. | Correspondence to A. Ju-Wei Wang and M. Sampaolesi, ashley.wang@kuleuven.be; maurilio.sampaolesi@kuleuven.be.
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35 | A novel 3D skeletal muscle model to study cancer cachexia R. Wüst1, L. Terrie1, A. Weisrock1|2, L. Thorrez1, Emanuele Berardi1 | 1Tissue Engineering Lab, Department of Development and Regeneration, KU Leuven Kulak, Kortrijk, Belgium; 2Univ. Lille, CNRS, Centrale Lille, UMR 9013, LaMcube, Lille, France.
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45 | Interleukin-4 prevents cancer-induced muscle wasting and promotes exercise-like metabolic adaptations Giacomo Rubini1, E. E. Cappellato1, L. C. Botinas1, S. Reano2, N. Filigheddu2, A. Bonetto3, F. Penna1, P. Costelli 1 | 1Dept. of Clinical and Biological Sciences, University of Turin, Italy; 2Dept. of Translational Medicine, University of Piemonte Orientale, Italy; 3Dept. of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
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