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Denervation does not induce muscle atrophy through oxidative stress
3169Downloads: 1659HTML: 469 -
Increasing autophagy does not affect neurogenic muscle atrophy
2336Downloads: 1149HTML: 110 -
Srf KO and wild-type mice similarly adapt to endurance exercise
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02 | Entrainment of skeletal muscle circaldian clock by 2-hydroxybutyrate, a noval exerkine Taoyue Yang1|2, L. Matta1, A. Bartelt1|3, K. Dyar1 | 1Institute for Diabetes and Cancer, Helmholtz Munich, Germany; 2Faculty of Medicine, Ludwig-Maximilian-Universität München, Germany; 3Traslational Nutritional Medicine, Technical University of Munich, Germany.
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13 | Generation of human stem cell-derived cardiac in vitro models to investigate the role of epicardial activation in adverse cardiac remodeling Margalida Campaner Socias1, V. Marini1, L. Rinvenuto1, A. Wang1, J. Zhang1, S. Morri1, D. Stalkopf1, R. Oida1, B. Sampaio1, M. Sampaolesi1|2 | 1Laboratory of Translational Cardiomyology, Stem Cell and Developmental Biology Unit, Department of Development and Regeneration, KU Leuven, Leuven, Belgium; 2Histology and Medical Embryology Unit, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Sapienza University of Rome, Rome, Italy.
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03 | The muscle out of breath? Limitations and adaptations in chronic diseases Angèle N. Merlet1|2, L.A Messonnier3|4, L. Féasson1|2 | 1Unité de Myologie, Service de Physiologie Clinique et de l'Exercice, Centre Référent Maladies Neuromusculaires Rares – Euro-NmD, Hôpital Universitaire de Saint-Etienne, Saint-Etienne, France; 2Laboratoire Interuniversitaire de Biologie de la Motricité, EA 7424, F-42023, Université de Lyon, UJM-Saint- Etienne, France; 3Univ. Savoie Mont Blanc, Laboratoire Interuniversitaire de Biologie de la Motricité, Chambéry, France; 4Institut Universitaire de France (IUF).
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40 | Role of glucocorticoids in cancer cachexia: focus on lipocalin 2 and iron homeostasis E. Wyart1, Giada Fregnan1, M. Colombera1, A. Scalera1, A. Menga2, P.E. Porporato1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Italy; 2Department of Health Sciences, Center for translational Research on Autoimmune & Allergic Diseases, University of Eastern Piedmont, Novara, Italy.
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41 | SRT2104 improves muscle and cognitive outcomes and has the potential to enhance μDys gene therapy in Duchenne muscular dystrophy Laura Lociuro1, A. Arcari2, O. Gjana1, G. Scolari1, S.R. Casati1|2, S. Zecchini2, M. Giovarelli2, C. Perrotta2, C. De Palma1 | 1Department of Medical Biotechnology and Translational Medicine (BioMeTra), Università degli Studi di Milano, Segrate (MI), Italy; 2Department of Biomedical and Clinical Sciences "Luigi Sacco" (DIBIC), Università degli Studi di Milano, Italy.
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23 | Preclinical evaluation of 3s-HMGB1 as a therapeutic strategy for Duchenne muscular dystrophy Federica Esposito1, E. Sbolli1, S. Curtarello1, E. Ruggieri1|2, M. Patrone1|2, M. Rodrigues3, V. Taglietti3, F. Relaix3, E. Vénéreau1|2 | 1Unit, Division of Genetics and Cellular Biology, IRCCS Ospedale San Raffaele, Milan, Italy; 2University Vita-Salute San Raffaele, Milan, Italy; 3Univ Paris-Est Créteil, INSERM, U955 IMRB, Créteil, France.
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06 | Pharmacological AMPK activation promotes higher levels of Pax7 expression in human muscle stem cells D. Michel1, A. Bouche1|2, R. Mounier3, D. Hannouche1|2, Thomas Laumonier1|2 | 1Cell Therapy and Musculoskeletal Disorders Laboratory, Department of Orthopedic Surgery, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland; 2Department of Cell Physiology and Metabolism, Faculty of Medicine, Geneva, Switzerland; 3Institut Neuromyogène, CNRS 5261 – INSERM U1315 - UCBL1, Lyon, France.
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32 | Trifolium pratense extract mitigates skeletal muscle atrophy: a nutraceutical approach for the prevention of sarcopenia Tommaso Raiteri1, H. Meskine2, M. Paiella1, A. Trabalzini1, I. Varfaj4, L. Salvadori2, F. Riuzzi1, R. Sardella4, F. Orlandi3, N. Filigheddu2, G. Sorci1 | 1Department of Medicine and Surgery, University of Perugia, Italy; 2Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 3Department of Civil and Environmental Engineering, University of Perugia, Italy; 4Department of Pharmaceutical Sciences, University of Perugia, Italy.
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43 | Synergistic negative effects of advanced glycation end products and tumor-conditioned medium on C2C12 myotubes and the protective activity of Vaccinium macrocarpon T. Raiteri2, Hajar Meskine1, L. Salvadori1, M. Paiella2, F. Prodam3, F. Riuzzi2, N. Filigheddu1 | 1Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 2Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 3Department of Health Science, University of Piemonte Orientale, Novara, Italy.
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44 | Targeted delivery of mir-486 to skeletal muscle: efficacy, tropism, and integrin dependency of MYOAAV2A vs. AAV9 Chiara Ricciardi1, S. Perni1, V. Sorrentino1|2 | 1Department of Molecular and Developmental Medicine, University of Siena, Italy; 2Interdepartmental Program of Molecular Diagnosis and Pathogenetic Mechanisms of Rare Genetic Diseases, Azienda Ospedaliera Universitaria Senese, Italy.
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15 | GDF5 therapeutic potential for Duchenne muscular dystrophy C. Gentil, A. Bourguiba, A. Vergnol, B. Cadot, Z. Guesmia, L. Saillard, P. Meunier, S. Falcone, L. Giordani, France Pietri-Rouxel | Sorbonne Université, INSERM, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
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34 | Hyaluronan enhances proliferation and myogenic differentiation of C2C12 murine myoblasts under inflammatory stress Fabio Ferrini, G. Annibalini, M. Battistelli, F. Fanelli, S. Moosavi, R. Osman, I. Capparucci, P. Sestili, E. Barbieri | Dept. of biomolecular sciences, University of Urbino, Italy.
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45 | Interleukin-4 prevents cancer-induced muscle wasting and promotes exercise-like metabolic adaptations Giacomo Rubini1, E. E. Cappellato1, L. C. Botinas1, S. Reano2, N. Filigheddu2, A. Bonetto3, F. Penna1, P. Costelli 1 | 1Dept. of Clinical and Biological Sciences, University of Turin, Italy; 2Dept. of Translational Medicine, University of Piemonte Orientale, Italy; 3Dept. of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
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24 | Smooth muscle cells from human vagina express functional transient receptor potential channels Francesco Palmieri1, R. Garella1, I. Cellai2, G. Guarnieri1, E. Maseroli2, S. Cipirani2, M. Annunziato2, P. Comeglio2, A. Morelli1, M. Maggi2, L. Vignozzi2, R. Squecco1 | 1Dip. di Medicina Sperimentale e Clinica, Università di Firenze, Italy; 2Dip. di Scienze Biomediche Sperimentali e Cliniche, Università di Firenze, Italy.
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35 | A novel 3D skeletal muscle model to study cancer cachexia R. Wüst1, L. Terrie1, A. Weisrock1|2, L. Thorrez1, Emanuele Berardi1 | 1Tissue Engineering Lab, Department of Development and Regeneration, KU Leuven Kulak, Kortrijk, Belgium; 2Univ. Lille, CNRS, Centrale Lille, UMR 9013, LaMcube, Lille, France.
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25 | Target adipogenic progenitors to cure Duchenne muscular dystrophy Luca Sali1, B. Periou2, A. Cojocaru1, E. Giry1, G. Severa2, L. Giordani3, V. Taglietti1, E. Malfatti1|2 | 1Univ. Paris-Est Créteil, INSERM, U955 IMRB, Créteil, France; 2Assistance Publique-Hôpitaux de Paris, Centre de Référence de Pathologie Neuromusculaire Nord-Est-Ile-de-France, Filnemus, Hôpital Henri Mondor, Créteil, France; European Reference Center for Neuromuscular Disorders, EURO-NMD, France; 3Sorbonne Université, INSERM UMRS 974, Association Institut de Myologie, Centre de Recherche en Myologie, Paris, France.
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36 | The effects of heat stress and exercise on skeletal muscle Chiara Malerba1, A. Laurino1, M. Serano, C. Pranzo1, F. Fiore1, E. Pierantozzi1, D. Rossi1|2, V. Sorrentino1|2 | 1Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy; 2Azienda Ospedaliero Universitaria Senese, Siena, Italy.
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07 | Role of GDF5 on macrophage polarization in the maintenance of muscle mass and function and during aging Maxime Gelin1, E. Hemery1, F. Truffault1, G. Juban2, C. Perrotta3, F. Pietri-Rouxel1, M. Traoré1, S. Falcone1 | 1Centre de Recherche en Myologie – U974 INSERM, Sorbonne Université, Institut de Myologie, Paris, France; 2Institut NeuroMyoGène, Physiopathologie et Génétique du Neurone et du Muscle Université Claude Bernard Lyon 1, CNRS U5261, Inserm U1315, University Lyon, Lyon, France; 3Department of Biomedical and Clinical Sciences Università degli Studi di Milano, Milan, Italy. | M. Traoré and S. Falcone contributed equally to this work and corresponding authors. s.falcone@institut-myologie.org; m.traore@institut-myologie.org.
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26 | Validation of a new multi-target antioxidant treatment for the therapy of Duchenne muscular dystrophy F. Fontana1|2, F. Carozzi1, G. Piccoli3, L. Nogara3, G. Romagnoli2, E. Petricci2, B. Blaauw3, M. Canton3, Libero Vitiello1, F. Galvagni2 | 1Dept. of Biology, Univ. of Padova, Italy; 2Dept. of Biotechnology, Chemistry and Pharmacy, Univ. of Siena, Italy; 3Dept. of Biomedical Sciences, Univ. of Padova, Italy.
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37 | Characterization of novel cancer cachexia preclinical models implementing chemotherapy and surgery Emma Elisabeth Cappellato, C. Fornelli, N.E. Cortez, V. Schiavo, P. Costelli, F. Penna | Department of Clinical and Biological Sciences, University of Torino, Italy.
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16 | Immunoproteasome inhibition positively impacts the gut-muscle axis in Duchenne muscular dystrophy Debora Mostosi1, A. Farini2, F. Strati3, M. Molinaro2, S. Saccone2, C. Amoroso3, B. Cassani4, E. Leonetti1, F. Caprioli5, F. Facciotti3, Y. Torrente1|2 | 1Stem Cell Laboratory, Dino Ferrari Center, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 2Neurology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; 3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy; 4Department of Medical Biotechnologies and Translational Medicine, University of Milan, Italy; 5Department of Pathophysiology and Transplantation, University of Milan, Unit of Gastroenterology and Endoscopy, Fondazione IRCCS Ca’ Granda, Ospedale Policlinico di Milano, Italy.
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27 | Polymeric nanoparticles as a favorable delivery system to enhance the anti-inflammatory action of n-palmitoylethanolamide, an endocannabinoid-like molecule E. Maretti1, C. Rustichelli1, B. Recchia1, G. Battaglia, E. de Nicola1, C. Fuoco2, A. Votta3, C. Gargioli2, E. Ferraro3, E. Leo1, Susanna Molinari1 | 1Dept. of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy; 2Dept. Of Biology, Tor Vergata Rome University, Rome, Italy; 3Dept. of Biology, University of Pisa, Pisa, Italy.
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