Abstracts of the 22nd Meeting of the Interuniversity Institute of Myology
Vol. 36 No. s1 (2026): Abstract book of the Padua Days on Muscle and Mobility Medicine 2026
https://doi.org/10.4081/ejtm.2026.15016

Abstract 017 | Full body in-bed gym: a synergistic, well-tolerated, low-impact strategy for healthy and active aging

Maria Chiara Maccarone 1|2, Ugo Carraro 2|3|4 | 1Department of Neuroscience, Physical Medicine and Rehabilitation Unit, University of Padova; 2A&C M-C Foundation for Translational Myology, Padua; 3Department of Biomedical Sciences, University of Padova, Padua, Italy; 4School of Physical Medicine and Rehabilitation, Department of Neuroscience, University of Padova, Italy.

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Received: 2 March 2026
Published: 2 March 2026
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In recent years, rehabilitation has increasingly integrated prehabilitation as well as secondary and tertiary prevention strategies, with the aim of promoting healthy and active aging. Evidence-based, non-pharmacological, and personalized interventions targeting the main determinants of longevity have therefore gained increasing attention, including physical exercise, nutrition, and strategies to promote sleep quality. Among these approaches, Full Body In-Bed Gym represents an innovative exercise protocol designed for adults aged over 65 years. It consists of aerobic and muscle- strengthening exercises that can be entirely performed in bed, engaging all body districts. This global, low-impact, and adaptable exercise modality is particularly suitable for frail individuals, older adults, and subjects with limited exercise tolerance, ensuring therapeutic continuity beyond the rehabilitative phase and supporting preventive care (1). When combined with tailored nutritional strategies (2), specifically, time-restricted eating (TRE) that involves restricting daily food intake to a defined time window, this approach promotes metabolic regulation through its effects on inflammatory pathways, autophagy, and circadian biology (3,4,5). This integrated approach may promote synergistic effects on body composition, muscle function, and metabolic muscle function, and metabolic health (2). In our cohort, 24 elderly subjects participated in the Full Body In-Bed Gym program over two months, with optional continuation (1). The exercise routine included simple movements targeting the upper limbs, lower limbs, trunk, and respiratory muscles, lasting 15-30 minutes per session, three to five times per week. TRE involves restricting daily food intake to a defined time window, promoting metabolic regulation through its effects on inflammatory pathways, autophagy, and circadian biology (3,4,5). In one case, a participant, U.C., undertook a combined intervention consisting of semi-fasting through time-restricted eating (TRE) paired with the Full Body In-Bed Gym program. Being Italian and adhering to a Mediterranean diet, he adopted a specific dietary approach known as Italian name:"3-NO" ("3-withouts", in English) that means "WITHOUT BREAD, WITHOUT WINE", "WITHOUT DINNER" (6). With such a strict, yet affordable dietary approach (combined with a total body workout in bed), in just two weeks he lost 2-3 kilos and reduced his waistline, achieving his main goal (6). This integrated approach may contribute to the prevention and management of sarcopenia, improvement of quality of life, and reduction of perceived pain in older adults, as previously demonstrated (1,2). Moreover, the exercise protocol appears to be well tolerated, favoring long-term adherence and continuity of physical activity among elderly individuals (1,2). Therefore, the Full Body In-Bed Gym protocol represents a promising option for promoting healthy aging, potentially reducing the disability-related burden associated with aging.

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1. Maccarone MC, Caregnato A, Regazzo G, Carriero A, Casellato G, Finamoni C, Jirillo R, Laskova O, Marigo E, Sánchez DY, Seno I, Venturin C, Veronese H, Ravara B, Giurati W, Carraro U, Masiero S. Effects of the Full-Body in-Bed Gym program on quality of life, pain and risk of sarcopenia in elderly sedentary individuals: preliminary positive results of a Padua prospective observational study. Eur J Transl Myol. 2023 Sep 26;33(3):11780. doi: 10.4081/ejtm.2023.11780. PMID: 37753778; PMCID: PMC10583150.

2. Forni R, Gargiulo P, Boretti G, Quadrelli M, Baccaglini T, Morra A, Ravara B, Zampieri S, Pond A, Carraro U, Maccarone MC, Masiero S. The Impact of Persevering Home Full-Body In-Bed Gym Exercise on Body Muscles in Aging: A Case Report by Quantitative Radio-Densitometric Study Using 3D and 2D Color CT. Diagnostics (Basel). 2024 Dec 13;14(24):2808. doi: 10.3390/diagnostics14242808. PMID: 39767169; PMCID: PMC11674620.

3. McLaren CW, Pearl RL, Smith GE, Anton SD. A Secondary Analysis of Caloric Restriction and Exercise Effects on Cognitive Function in Functionally Limited Postmenopausal Women with Overweight or Obesity. Nutrients. 2025 Jun 22;17(13):2075. doi: 10.3390/nu17132075. PMID: 40647181; PMCID: PMC12251159.

4. Ezzati A, Tamargo JA, Golberg L, Haub MD, Anton SD. The Effects of Time-Restricted Eating on Inflammation and Oxidative Stress in Overweight Older Adults: A Pilot Study. Nutrients. 2025 Jan 17;17(2):322. doi: 10.3390/nu17020322. PMID: 39861451; PMCID: PMC11768921.

5. Ezzati A, Rosenkranz SK, Horne BD. Importance of Intermittent Fasting Regimens and Selection of Adequate Therapy on Inflammation and Oxidative Stress in SARS- CoV-2 Infection. Nutrients. 2022 Oct 14;14(20):4299. doi: 10.3390/nu14204299. PMID: 36296982; PMCID: PMC9607422.

6. Carraro Ugo. How to rejuvenate at 80’s. CLEUP sc, University of Padova, Italy. 2024. ISBN 978-88-5495-727-5. 2024: 1-190.

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1.
Maccarone MC. Abstract 017 | Full body in-bed gym: a synergistic, well-tolerated, low-impact strategy for healthy and active aging: Maria Chiara Maccarone 1|2, Ugo Carraro 2|3|4 | 1Department of Neuroscience, Physical Medicine and Rehabilitation Unit, University of Padova; 2A&C M-C Foundation for Translational Myology, Padua; 3Department of Biomedical Sciences, University of Padova, Padua, Italy; 4School of Physical Medicine and Rehabilitation, Department of Neuroscience, University of Padova, Italy. Eur J Transl Myol [Internet]. 2026 Mar. 2 [cited 2026 Apr. 17];36(s1). Available from: https://www.pagepressjournals.org/bam/article/view/15016