Case Reports
Vol. 6 (2016)
https://doi.org/10.4081/cdr.6.5945

Two cases of monoclonal nodular pulmonary amyloidosis and review of the literature

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Received: 18 April 2016
Published: 21 December 2016
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Pulmonary nodule, Amyloidosis, Immunoglobulin
Cardiothoracic Surgery, Pathology, Pulmonology

Authors

Kendal M. Endicott
Division of Cardiothoracic Surgery, Veterans Affairs Medical Center, Washington, DC, United States.
Conor F. Hynes
Division of Cardiothoracic Surgery, Veterans Affairs Medical Center, Washington, DC, United States.
Cindy M. Hsieh
Department of Pathology, The George Washington University, Washington, DC, United States.
Edina Paal
Department of Pathology, The George Washington University, Washington, DC; Pathology and Laboratory Medicine Service, Veterans Affairs Medical Center, Washington, DC, United States.
Gregory Trachiotis
gregory.trachiotis@va.gov
Division of Cardiothoracic Surgery, Veterans Affairs Medical Center, Washington, DC; Division of Cardiothoracic Surgery, The George Washington University, Washington, DC, United States.
Nodular pulmonary amyloidosis (NPA) is an uncommon pathology of insoluble protein depositing in pulmonary parenchyma. This localized pulmonary form of amyloidosis is most often found to contain combinations of kappa and lambda immunoglobulin light chain and immunoglobulin heavy chain proteins with a polyclonal lymphoplasmacystic infiltrate. Herein we present two cases of NPA of the rarely reported monoclonal (light-chain restricted) form with review of the literature and discussion of the clinical, radiographic, and histologic features of NPA.

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Two cases of monoclonal nodular pulmonary amyloidosis and review of the literature. (2016). Chest Disease Reports, 6(1). https://doi.org/10.4081/cdr.6.5945

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