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• 010 | Combining a gemcitabine-derived prodrug, GEM-C18, with nanoparticles to counteract acidic ph-dependent chemoresistance of pancreatic adenocarcinoma Francesca Fracasso, Marilena Ardone, Tiago Miguel Amaral Carvalho^1|2, Barbara Rolando³, Silvia Arpicco³, Valeria Bincoletto³, Francesca Bianco⁴, Alessandra Fiorio Pla⁴, Daniela Isabel Abbrescia⁵, Ylenia Antonacci⁵, Chrysovalentinos Pousis⁵, Sharon Natasha Cox¹, Flaviana Marzano⁵, Graziano Pesole¹, Apollonia Tullo⁵, Stephan Joel Reshikn¹, Rosa Angela Cardone¹ | ¹Dept of Biosciences, Biotechnology and Environment, University of Bari, ltaly; ²CICS-UBI-Health Sciences Research Center, Universidade da Beira Interior, Covilhã, Portugal; ³Dept. of Drug Science and Technology, University of Turin, ltaly; ⁴Dept of Life Sciences and Systems Biology, University of Turin, Italy ⁵Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies – IBIOM - CNR, Bari, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15262

  37