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• 028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale¹, Giuseppa D’Amico¹, Martina Di Marco¹, Giuseppina Poppa², Pierlorenzo Maria Veiceschi³, Alessandro Lo Giudice¹, Francesca Chiara Cecala¹, Paola Limoncelli², Ilaria Giusti², Vincenza Dolo², Claudia Campanella¹, Francesca Rappa¹, Rosario Barone¹, Giovanni Tringali³, Francesco Cappello¹, Celeste Caruso Bavisotto¹ | ¹Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; ²Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; ³Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15280

  28

• 125 | Impact of 2D and 3D in vitro culture models on extracellular vesicles in human ovarian cancer Giulia Di Fazio¹, Giuseppina Poppa¹, Giuseppe Cammarata², Sandra D’Ascenzo¹, Vincenza Dolo¹, Simona Taverna², Ilaria Giusti¹ | ¹Department of Life, Health and Environmental Sciences, University of L’Aquila, Italy; ²Institute of Translational Pharmacology IFT, National Research Council of Italy CNR, Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15377

  43