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• 171 | Development of a 3D ex vivo model of human intestinal organoids for the study of inflammatory bowel diseases Giulia Maria Giorgia Lo Piano¹, Massimo Biondo¹, Adelaide Carista¹, Domiziana Picone¹, Stefano Burgio^2|3, Alberto Fucarino⁴, Francesca Rappa¹, Alessandro Pitruzzella¹, Fabio Bucchieri¹ | ¹Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; ²Euro-Mediterranean Institute of Science and Technology IEMEST, Palermo, Italy; ³Department of Medicine and Surgery, Kore University of Enna, Enna, Italy; ⁴Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Como, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15423

  19

• 155 | Mitochondrial dynamics and therapeutic insights in spinal muscular atrophy: effects of MFN2 boosting in motoneurons and human fibroblasts Francesco Paolo Zummo¹, Serena Stanga¹, Letizia Paladino², Maria Beltran³, Francesco Fedeli⁴, Maria Rosa Soler³, Fabio Bucchieri⁵, Marina Boido¹ | ¹Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy; ²E-Campus University, Palermo, Italy; ³Neuronal Signaling Unit, Experimental Medicine Department, University of Lleida-IRBLleida, Lleida, Spain; ⁴University of Pavia, Italy; ⁵Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15407

  19