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• 095 | Nanoplastic as modulators of human immune responses: effect on natural killer and T cells Francesca D’Ascanio^1|2|3, Isabel María Vallejo Bermúdez^4|5, Domenico De Bellis^1|2, Giulia Colasante,^1|2, Arianna Aquilini^1|2, Sabino Porro^1|2, Tamer Shibl Ali Esmail^1|2, Ayesha Younas^1|2, Mariagiulia Filoso^1|2, Luana D’Onofrio^1|2, Piero Chiacchiaretta^1|6, Melania Dovizio^1|6, Patrizia Ballerini^1|6, Piero Di Carlo^1|6, Alejandra Pera^4|5, Bruna Sinjiari⁶, Paola Lanuti^1|2. | ¹Center for Advanced Studies and Technology CAST, "G.d'Annunzio" University of Chieti-Pescara, Chieti, Italy; ²Department of Medicine and Aging Sciences, "G.d'Annunzio" University of Chieti-Pescara, Chieti, Italy; ³Department of Humanities, Law and Economics, “Leonardo da Vinci” University, Torrevecchia Teatina, Italy; ⁴Immunology and Allergy Group GC01, Instituto Maimónides de Investigación Biomédica IMIBIC, Córdoba, Spain; ⁵Molecular Immunology Group CTS208, Department of Cell Biology, Physiology and Immunology, University of Cordoba, , Spain; ⁶Department of Innovative Technologies in Medicine and Dentistry, University "G d'Annunzio" of Chieti-Pescara, Chieti, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15347

  125

• 051 | Optimization of a combined spectral and imaging flow cytometry protocol integrated with AI for rapid human microbiota screening Arianna Aquilini-Mummolo^1|2, Francesca D’Ascanio^1|2|3, Giulia Colasante^1|2, Domenico De Bellis^1|2, Pasquale Simeone⁴, Sabino Porro^1|2, Tamer Esmail^1|2, Ayesha Younas^1|2, Luana D’Onofrio^1|2, Isabel Vallejo Bermúdez^5|6, Camilla Cichella², Mariagiulia Filoso^1|2, Chiara Porro⁴, Paola Lanuti^1|2. | ¹Department of Medicine and Aging Sciences, University “G d’Annunzio”, Chieti-Pescara, Chieti; ²Center for Advanced Studies and Technology CAST, University “G d’Annunzio”, Chieti-Pescara; ³Department of Humanities, Law and Economics, “Leonardo da Vinci” University, Torrevecchia Teatina, Italy; ⁴Department of Clinical and Experimental Medicine, University of Foggia, Italy; ⁵Molecular Immunology Group CTS208, Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; ⁶Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15303

  121

• 122 | Tangential flow filtration enables high-yield isolation and stable characterization of grape-derived extracellular vesicles for therapeutic application Sabino Porro^1|2, Tamer Esmail^1|2, Francesca D’Ascanio^1|2|3, Giulia Colasante^1|2, Arianna Aquilini-Mummolo,^1|2, Luana D’Onofrio^1|2, Mariagiulia Filoso^1|2, Ayesha Younas^1|2, Isabel Maria Vallejo Bermudez^4|5, Camilla Cichella^1|2, Michela Battistelli⁶, Anna Piro⁷, Serena Veschi⁷, Serena Pilato⁷, Antonella Fontana⁷, Alessandro Cama⁷, Angelo Cichelli⁸, Paola Lanuti^1|2, Federica Flamminii⁹ | ¹Department of Medicine and Aging Sciences, University “G d’Annunzio” of Chieti-Pescara, Italy; ²Center for Advanced Studies and Technology CAST; ³Molecular Immunology Group CTS208 Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy; ⁴Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain; ⁵Immunology and Allergy Group GC01, Maimonides Biomedical Research Institute of Cordoba IMIBIC, University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain; ⁶Department of Biomolecular Sciences DISB University of Urbino Carlo Bo, Italy; ⁷Department of Pharmacy, University “G d’Annunzio” of Chieti-Pescara, Italy; ⁸Department of Innovative Technologies in Medicine & Dentistry, University “G d’Annunzio” of Chieti-Pescara, Italy; ⁹Department of Promotion of Human Sciences and Quality of Life, San Raffaele Telematic University, Rome, Italy.

  Società Italiana di Biologia Sperimentale

  31-03-2026

  https://doi.org/10.4081/jbr.2026.15374

  113