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069 | Comparative analysis of inflammatory and redox responses in human and rat macrophages exposed to calcium-doped mesoporous silica nanoparticles Styliani Axypolitou1, Antonietta Ligas2, Ioannis Tsamesidis1, Georgia K. Pouroutzidou1, Pier Luigi Fiori2, Antonella Pantaleo2, Eleana Kontonasaki1 | 1Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece 2Department of Biomedical Sciences, Division of Microbiology and Virology, University of Sassari, Italy.
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065 | Phytochemical profile, oxidative response and antimicrobial activity of Scutellaria lateriflora extract against Staphylococcus aureus Dionysia Amanatidou1, Ioannis Tsamesidis1|2, Stylaini Axipolitou2, Nektaria Grammatika2, Antonella Pantaleo3, Eleana Kontonasaki2, Phaedra Eleftheriou1 | 1Department of Biomedical Sciences, International Hellenic University, Thessaloniki, Greece; 2Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece; 3Department of Biomedical Science, University of Sassari, Italy.
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148 | Lysosomal and synuclein pathology in IPSC-derived dopaminergic neurons from GBA1-mutant Parkinson’s disease patients Gaia Pinna1, Giuseppe Uras1|2, Veronica Lentini1, Luca Miuzzo1, Sara Del Pozo3, Federico Fierli3, Anthony Schapira3, Antonella Pantaleo1 | 1Department of Biomedical Science, University of Sassari, Italy; 2Department of Haematology, UCL, London, United Kingdom; 3Department of Clinical and Movement Neurosciences, UCL, London, UK.
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055 | Investigating microgravity’s dual impact through neuronal and cyanobacterial models: mechanistic insights into spirulina bioactivity and Parkinson’s disease pathology Mohammed Amine El Faqir1|2, Giuseppe Uras1, Alessia Manca2, Veronica Lentini2, Antonella Pantaleo2 | 1Department of Clinical Neuroscience, Institute of Neurology, University college London, UK; 2Department of Biomedical Science, University of Sassari, Italy.
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