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POLY(LACTIC ACID) PLASTICS CONTAMINATION (PLASTAMINATION): SIZE-DEPENDENT EFFECTS OF PLA-DERIVED NANOPLASTICS ON EARLY ZEBRAFISH DEVELOPMENT Giusy VULTAGGIO1, Martina DI MARCO1, Antonietta SANTORO2, Marianna MARINO2, Erwin Pavel LAMPARELLI2, Giovanna DELLA PORTA2, Francesco CAPPELLO1,3, Federica SCALIA1,4, Marta Anna SZYCHLINSKA5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; 4Department of Medicine and Surgery - Kore University of Enna, Enna, Italy; 5Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Italy
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033 | Innovative autonomous surface vehicles for enhanced welfare and continuous monitoring in sustainable aquaculture Alex Carnevale1, Ayman El Qemmah2, Rosario Sorbello3, Alessia Avolicino1 | 1DIBEST, Università della Calabria; 2DIMES, Università della Calabria; 3Dipartimento di Ingegneria Industriale e dell’Informazione, Università eCampus, Italy.
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055 | Investigating microgravity’s dual impact through neuronal and cyanobacterial models: mechanistic insights into spirulina bioactivity and Parkinson’s disease pathology Mohammed Amine El Faqir1|2, Giuseppe Uras1, Alessia Manca2, Veronica Lentini2, Antonella Pantaleo2 | 1Department of Clinical Neuroscience, Institute of Neurology, University college London, UK; 2Department of Biomedical Science, University of Sassari, Italy.
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188 | Frontal sinus osteomas in the mummy of a poor clare nun from Fara in Sabina (17th-18th century) Luca Ventura1, Federico Bruno2, Veronica Forte1, Nadia Gabriele1, Irene Faenza3, Enrico Petrella4, Gianandrea Pasquinelli5, Mirko Traversari5 | 1UOC di Anatomia Patologica, Ospedale San Salvatore, L’Aquila, Italy; 2UOC di Neuroradiologia e Radiologia Interventistica, Ospedale San Salvatore, L’Aquila, Italy; 3Dipartimento di Scienze Biomediche e Neuromotorie DIBINEM, Alma Mater Studiorum Università di Bologna, Italy; 4Dipartimento di Radiologia, AUSL Romagna, Ospedale Morgagni-Pierantoni, Forlì, Italy; 5Dipartimento di Scienze Mediche e Chirurgiche DIMEC, Alma Mater Studiorum Università di Bologna, Italy.
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109 | Novel eco-sustainable approaches to prevent and mitigate emerging contaminants-induced physiological changes in a marine model organisms Cristiana Roberta Multisanti1, Marina Russo2, Paolo Pastorino3, Giuseppe Piccione1, Federica Impellitteri1, Caterina Faggio4|5 | 1Dept of Veterinary Sciences, University of Messina, Messina, Italy; 2Dept of Chemical, Biological, Pharmaceutical, and Environmental Sciences, Messina Institute of Technology c/o, University of Messina, Messina, Italy; 3Zooprophylactic Institute of Piedmont, Liguria and Valle d'Aosta, Turin, Italy; 4Dept of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 5Dept of Eco-sustainable Marine Biotechnology, SZN Anton Dohrn, Naples, Italy.
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002 | Ecotoxicology in a changing planet: challenges and opportunities in the Anthropocene Paolo Pastorino1, Antonia Concetta Elia2, Monia Renzi3, Caterina Faggio4|5, Marino Prearo1, Damià Barceló6 | 1Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Torino, Italy; 2Department of Chemistry, Biology and Biotechnology, University of Perugia, Italy; 3Department of Life Sciences, University of Trieste, Italy; 4Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; 5Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy; 6Department of Chemistry and Physics, University of Almería, Carretera Sacramento, Almería, Spain.
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150 | New strategies to counteract dopaminergic degeneration: in vitro and in vivo neurotrophic properties of a tetrahydro-isoquinoline derivative as a novel mGlu2/3 agonist/positive allosteric modulator Miriana Scordino1, Giulia Urone1, Monica Frinchi1, Lucia Seidita1, Alessandra Montalbano2, Marilia Barreca2, Paola Barraja2, Maria Valeria Raimondi2, Roberta Bivacqua2, Fanny Malhaire3, Cyril Goudet3, Giuseppa Mudò1, Virginia Spanò2, Valentina Di Liberto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; 3IGF, Université de Montpellier, CNRS, INSERM, France.
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076 | Iron-driven redox dysregulation fuels psoriatic signaling in CARD14 e138a mutant keratinocytes Cristiana Galeano1, Anna Martina Battaglia1, Emanuele Giorgio1, Lavinia Petriaggi1, Giuseppe Natali2, Flavia Biamonte1 | 1Laboratory of Biochemistry and Cell Biology, Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Italy; 2Department of Life Science, Magna Graecia University of Catanzaro, Italy.
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COMPARISON OF THE POTENTIAL CHRONIC TOXICITY OF POLYPROPYLENE AND POLYLACTIC ACID TO THE AMPHIPOD GAMMARUS AEQUICAUDA Francesca BIANDOLINO1, Ermelinda PRATO1, Amalia AMATO1,2, Loredana MANFRA2,5, Giovanni LIBRALATO2,3, Luisa ALBARANO3, Valerio ZUPO6, Maria COSTANTINI2 | 1National Research Council, Water Research Institute (IRSA-CNR), Taranto, Italy; 2Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy; 3Department of Biology, University of Naples Federico II, Naples, Italy; 4Stazione Zoologica Anton Dohrn, Department of Marine Animal Conservation and Public Engagement, Naples, Italy; 5Institute for Environmental Protection and Research (ISPRA), Rome, Italy; 6Stazione Zoologica Anton Dohrn, Department of Ecosustainable Marine Biotechnology, Ischia, Italy
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121 | Probiotics effect on brain-gut axis mediated by nanovescicles Alessandro Lo Giudice1, Giuseppa D’Amico1, Melania Ionelia Gratie1, Letizia Paladino2, Giusy Vultaggio1, Adelaide Carista1, Francesco Cappello1, Vita Di Stefano3, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy; 2Department of Theoretical and Applied Sciences, eCampus University, Novedrate [CO], Italy; 3Department of Biological, Chemical, and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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028 | Modelling glioblastoma multiforme microanatomical complexity with patient-derived 3D spheroids: a promising therapeutic tool for advancing precision medicine Alessandra Maria Vitale1, Giuseppa D’Amico1, Martina Di Marco1, Giuseppina Poppa2, Pierlorenzo Maria Veiceschi3, Alessandro Lo Giudice1, Francesca Chiara Cecala1, Paola Limoncelli2, Ilaria Giusti2, Vincenza Dolo2, Claudia Campanella1, Francesca Rappa1, Rosario Barone1, Giovanni Tringali3, Francesco Cappello1, Celeste Caruso Bavisotto1 | 1Institute of Human Anatomy and Histology, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Italy; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3Department of Neurosurgery, National Relevance and High Specialization Hospital Trust ARNAS Civico, Palermo, Italy.
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132 | Environmental DNA: a preliminary characterization of invertebrate biodiversity in a Sicilian river Manuela Mauro1, Rosi De Luca1, Mario Lo Valvo1, Slobodanka Radovic2, Aiti Vizzini1, Grazia Orecchio1, Francesco Longo1, Vinicius Queiroz3, Rosario Badalamenti1, Claudio Gargano1, Mirella Vazzana1 | 1Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche STEBICEF, Università Degli Studi di Palermo, Palermo, Italy; 2IGA Technology Services Srl, Udine, Italy; 3Department of Physiology, Institute of Biosciences, University of São Paulo, Brazil.
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ENVIRONMENTAL NANOPLASTIC ACCUMULATION AND NEURODEGENERATIVE DISEASE IN ANIMAL MODELS Beatrice ZARRILLI1,2, Nicola B. MERCURI2,3, Rosaria MECCARIELLO1, Ezia GUATTEO1,2 | 1University of Naples ‘Parthenope’, Department of Medical, Human Movement and Well-being Sciences, Naples, Italy; 2Experimental Neurology Laboratory, Fondazione Santa Lucia IRCCS, Rome, Italy; 3University of Rome Tor Vergata, Department of Systems Medicine, Rome, Italy
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190 | Surface engineering of titanium implants with vanillin-chitosan and cerium doped-nanoparticle coatings for improved osteoimmune response Ioannis Tsamesidis1, Styliani Axypolitou1, Georgia K. Pouroutzidou1, Maria Bousnaki1, Dimitrios Bikiaris1, Evi Christodoulou1, Antonios D. Anastasiou2, Eleana Kontonasaki1 | 1Aristotle University of Thessaloniki, Greece 2University of Manchester, UK.
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107 | Protective effects of hydroxytyrosol against dichlorodiphenilethylene-induced oxidative injury in liver cells Vincenzo Migliaccio1, Ilaria Di Gregorio1, Martina Coletta1, Giuliana Panico2, Assunta Lombardi2, Lillà Lionetti1 | 1Dept Chemistry and Biology “Adolfo Zambelli”, University of Salerno, Italy; 2Dept Biology, University Federico II, Napoli, Italy.
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057 | Bioactive metabolites from antarctic sponge-associated bacteria: bioactivity and cytotoxic assessment Claudia Gravagno1|2, Stefano Putaggio2, Teresa Romeo2|3, Annamaria Russo2, Carmen Rizzo2|4, Ester Tellone2, Angelina Lo Giudice4 | 1Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Messina, Italy; 2University of Messina, Italy; 3National Institute for Environmental Protection and Research, Milazzo [ME], Italy; 4National Research Council, Institute of Polar Sciences, Messina, Italy.
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148 | Lysosomal and synuclein pathology in IPSC-derived dopaminergic neurons from GBA1-mutant Parkinson’s disease patients Gaia Pinna1, Giuseppe Uras1|2, Veronica Lentini1, Luca Miuzzo1, Sara Del Pozo3, Federico Fierli3, Anthony Schapira3, Antonella Pantaleo1 | 1Department of Biomedical Science, University of Sassari, Italy; 2Department of Haematology, UCL, London, United Kingdom; 3Department of Clinical and Movement Neurosciences, UCL, London, UK.
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The tools of the Ancient Egyptian embalmers
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