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067 | Redefining amphibian innate immunity: first in vitro and in vivo evidence of phagocytic function in blood cells Valbona Aliko1, Erion Sukaj2, Cristiana Roberta Multisanti3, Federica Impelliteri4, Caterina Faggio4 | 1University of Tirana, Faculty of Natural Sciences, Department of Biology, Tirana, Albania; 2Western Balkans University, Faculty of Medicine and Technical Medical Sciences, Tirana, Albania; 3Department of Veterinary Sciences, University of Messina, Italy; 4University of Messina, Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, Messina, Italy.
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017 | Targeting lipogenesis promotes the synergistic effect of the selective HDAC inhibitor ITF3756 with bortezomib in colon cancer cells Marzia Franzò1, Giovanni Pratelli1, Federica Affranchi2, Antonietta Notaro2, Michela Giuliano2, Sonia Emanuele1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics, Biochemistry Building, University of Palermo, Italy; 2Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy.
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007 | Dysregulation of the trans-sulfuration-sphingosine-1-phosphate signaling axis in glioblastoma: preclinical evidence Elsa Calcaterra1, Michela Campolo1, Melania Correale2, Rossella Basilotta1, Maria Caffo3, Roberta D’Emmanuele Di Villa Bianca2, Emma Mitidieri2, Giovanna Casili1, Emanuela Esposito1 | 1Department of Chemical, Biological, Pharmaceutical, Environmental Sciences, University of Messina, Italy; 2Department of Pharmacy, School of Medicine and Surgery, University of Study of Naples - Federico II, Naples, Italy; 3Unit of Neurosurgery, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
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DEGRADATION PATHWAYS OF BIODEGRADABLE FILMS IN AQUATIC ECOSYSTEMS: THE ROLE OF ENVIRONMENTAL FACTORS IN MICROPLASTICS FORMATION Annalisa APICELLA, Loredana INCARNATO | Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA), Italy
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043 | Hemocyte motility integrated into a multimarker ecophysiological approach for thermal stress assessment in native and invasive bivalve species Gayatri Udayan, Claudio Calabrese1, Daniele Arduini; Antonella Giacovelli1, Maria Elena Giordano1, Adriana Giangrande1|2, Maria Giulia Lionetto1|2 | 1Dept Biological and Environmental Sciences and Technologies DiSTeBA, University of Salento; 2NBFC, National Biodiversity Future Center, Palermo, Italy.
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097 | Pharmaceutical pollution in aquatic environments: effects of valsartan on Mytilus galloprovincialis Giorgia Giurlanda1, Alessia Caferro1, Mariacristina Filice1, Maria Assunta Iovine1, Alfonsina Gattuso1, Federica Impellitteri2, Caterina Faggio3, Maria Carmela Cerra1, Sandra Imbrogno1 | 1Department of Biology, Ecology, and Earth Sciences, University of Calabria, Arcavacata di Rende, Cosenza, Italy; 2Department of Veterinary Sciences, University of Messina, Italy; 3Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy.
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166 | Attenuation of Pseudomonas aeruginosa virulence by engineered phage Domenico Franco1, Salvatore Papasergi2, Francesco Mediati1, Salvatore P.P. Guglielmino1, Laura Maria De Plano1 | 1Department of Chemical, Biological, Pharmaceutical and Environmental Sciences ChiBioFarAm, University of Messina, Italy; 2Institute of Translational Pharmacology of the National Research Council; 3Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian Workers’Compensation Authority INAIL, Italy.
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PRELIMINARY RESULTS ON MICROPLASTIC AND NANOPLASTIC IMPACT IN VIRUS AND BACTERIAL REPLICATION Nicoletta CAPUANO1,2, Alessia GIANNATTASIO3, Noemi CAFA’1,2, Anna BARBATO1,2, Mariarosa SCOGNAMIGLIO4, Vincenzo BELGIORNO5, Luca RINALDI6, Veronica FOLLIERO1,2, Antonio BUONERBA3, Gianluigi FRANCI1,2 | 1Dipartimento di Medicina, Chirurgia e Odontoiatria, Scuola Medica Salernitana, Università degli Studi di Salerno, Baronissi (SA), Italia; 2UOS di Microbiologia e Virologia, AOU San Giovanni di Dio e Ruggi D’Aragona, Salerno, Italia; 3Dipartimento di Chimica e Biologia, Università degli Studi di Salerno, Fisciano (SA), Italia; 4Dipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Fisciano (SA), Italia; 5Dipartimento di Ingegneria Civile, Università degli Studi di Salerno, Fisciano (SA), Italia; 6Dipartimento di Medicina e Scienze della Salute, Università degli Studi del Molise, Italy
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096 | Hidden threats: trojan horse effects of microplastics enhance the toxicity of tire-wear chemicals in marine ecosystems Federica Davì, Roberta Fusco, Davide Di Paola | Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy.
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EVALUATING ENDOCRINE AND OXIDATIVE EFFECTS OF POLYLACTIC ACID NANOPLASTICS (PLA-NPs) ON BREAST CELL MODELS Maria Denise AMICO1, Antonietta SANTORO2, Erwin Pavel LAMPARELLI2, Giovanna DELLA PORTA2, Magdalena GORSKA-PONIKOWSKA3,4,5, Francesca RAPPA1,5, Fabio BUCCHIERI1, Francesco CAPPELLO1,5 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Italy; 2Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana”, University of Salerno, Italy; 3Department of Medical Chemistry, Medical University of Gdansk, Poland; 4Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Germany; 5Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
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055 | Investigating microgravity’s dual impact through neuronal and cyanobacterial models: mechanistic insights into spirulina bioactivity and Parkinson’s disease pathology Mohammed Amine El Faqir1|2, Giuseppe Uras1, Alessia Manca2, Veronica Lentini2, Antonella Pantaleo2 | 1Department of Clinical Neuroscience, Institute of Neurology, University college London, UK; 2Department of Biomedical Science, University of Sassari, Italy.
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163 | SIX-2G as a novel compound to attenuate airway inflammation in cystic fibrosis through modulation of molecular chaperones Giuseppa D’Amico1, Federica Scalia2, Maria Antonella Augello1, Giusi Alberti1, Roberta Bivacqua3, Marilia Barreca3, Rosario Barone1, Francesco Cappello1, Paola Barraja3, Alessandra Montalbano3, Celeste Caruso Bavisotto1 | 1Department of Biomedicine, Neuroscience and Advanced Diagnostics BIND, University of Palermo, Italy; 2Department of Medicine and Surgery, Kore University of Enna, Italy; 3Department of Biological, Chemical, Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy.
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03 | MICRO- AND NANOPLASTICS: A NEW UNCONVENTIONAL RISK FACTOR FOR CARDIOVASCULAR HEALTH Raffaele Marfella | Departments of Advanced Medical and Surgical Sciences, University of Naples, Italy
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018 | BSA nanoparticles containing collagenases and doxorubicin to enhance therapeutic efficacy in 3D models of solid tumor Gabriele Lo Buglio1|2, Alessandra Lo Cicero1, Simona Campora1, Paolo Cinà3Samuel Lenton2, Vito Foderà2, Giulio Ghersi1|3 | 1Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF, University of Palermo, Italy; 2Department of Pharmacy, University of Copenhagen, Denmark; 3Abiel srl, Palermo, Italy.
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