Primary melanoma of the bladder: Case report and review of the literature

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Francesco Barillaro *
Marco Camilli
Paolo Dessanti
Nader Gorji
Fabio Chiesa
Alessandro Villa
Alessandro Pastorino
Carlo Aschele
Enrico Conti
(*) Corresponding Author:
Francesco Barillaro | francesco.barillaro@asl5.liguria.it

Abstract

Skin melanoma represents one of the most common and lethal solid tumor. It usually develops on the skin but it can occur in any tissues with melanine- containing-cells (extracutaneous malignant melanoma). Only 4-5% of malignant melanomas originate in extracutaneous tissues, and they have an extremely lethal behavior (1). These non-skin malignant melanomas are rare but extremely aggressive. Primary melanoma of the genitourinary tract accounts for less than 0.2% of all melanomas. To date only 28 cases of primary bladder melanoma (PMM) are described. We report a rare case of PMM of the bladder in a 72 years old man treated with radical cystectomy and immunotherapy with Nivolumab.

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