Images in Emergency Open access

If you hear a new worrisome heart murmur…

Authors

Published
13 February 2025
Section
Images in Emergency

Abstract

An 86-year-old woman presented to our emergency department for acute dyspnea without chest pain. She had taken amoxicillin/clavulanate 1 g/q12h for acute bronchitis. She underwent a left nephrectomy for cancer twenty years earlier. Blood pressure, heart rate, peripheral oxygen saturation, respiratory rate, and body temperature were 110/60 mmHg, 112 bpm, 90% with a non-rebreather mask (15 L/min), 25 breaths/min, and 36.5°C, respectively. Arterial blood gas documented pH 7.31, pCO2 29 mmHg, pO2 49 mmHg, SatO2 90%, HCO3 14.6 mEq/L, lactates 3.8 mmol/L. Chest examination revealed absent vesicular murmur in the basal regions, crackles in the upper ones, and a pansystolic murmur. A lung ultrasound showed a white lung pattern with a severe pleural effusion and non-collapsible inferior vena cava. Laboratory findings documented WBC 18,610/mm3 with CRP 84 mg/L (n.v.<10), AST 489 U/L (n.v. 11-34), ALT 296 U/L (n.v.<33), and troponin T 5191 ng/L (n.v.<20). ECG and echocardiography are reported in Figure 1 and Video 1, respectively.

References

  1. Reddy SG, Roberts WC. Frequency of rupture of the left ventricular free wall and ventricular septum among necropsy cases of fatal acute myocardial infarction since introduction of coronary care units. Am J Cardiol 1989;63:906-11. DOI: https://doi.org/10.1016/0002-9149(89)90137-9
  2. Damluji AA, van Diepen S, Katz JN, et al. American Heart Association Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Surgery and Anesthesia; and Council on Cardiovascular and Stroke Nursing. Mechanical Complications of Acute Myocardial Infarction: A Scientific Statement From the American Heart Association. Circulation 2021;144:e16-e35. DOI: https://doi.org/10.1161/CIR.0000000000000985
  3. David TE. Post-infarction ventricular septal rupture. Ann Cardiothorac Surg 2022;11:261-7. DOI: https://doi.org/10.21037/acs-2021-ami-111
  4. Crenshaw BS, Granger CB, Birnbaum Y, et al. Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. GUSTO-I (Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries) Trial Investigators. Circulation 2000;101:27-32. DOI: https://doi.org/10.1161/01.CIR.101.1.27
  5. Shahreyar M, Akinseye O, Nayyar M, et al. Post-Myocardial Infarction Ventricular Septal Defect: A Comprehensive Review. Cardiovasc Revasc Med 2020;21:1444-9. DOI: https://doi.org/10.1016/j.carrev.2018.11.017
  6. Rogers WJ, Frederick PD, Stoehr E, et al. Trends in presenting characteristics and hospital mortality among patients with ST elevation and non-ST elevation myocardial infarction in the National Registry of Myocardial Infarction from 1990 to 2006. Am Heart J 2008;156:1026–34. DOI: https://doi.org/10.1016/j.ahj.2008.07.030
  7. Lemery R, Smith HC, Giuliani ER, et al. Prognosis in rupture of the ventricular septum after acute myocardial infarction and role of early surgical intervention. Am J Cardiol 1992;70:147-51. DOI: https://doi.org/10.1016/0002-9149(92)91266-7
  8. Ibanez B, James S, Agewall S, et al. ESC Scientific Document Group. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2018;39:119–77. DOI: https://doi.org/10.1093/eurheartj/ehx393

Metrics

Citations and online attention from Dimensions, Altmetric and PlumX.