Hearing loss, why bronchial tree may be involved?


Submitted: 19 January 2024
Accepted: 23 January 2024
Published: 25 January 2024
Abstract Views: 973
PDF: 50
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Authors

  • Marisa Anelli Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo; Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo; Department of Health Sciences, University of Milan, Italy.
  • Federico Raimondi Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo, Italy. https://orcid.org/0000-0001-9599-6864
  • Luca Novelli Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo, Italy. https://orcid.org/0000-0002-2705-248X
  • Chiara Allegri Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo; Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo; Department of Health Sciences, University of Milan, Italy.
  • Simone Bonetti Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo; Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo; Department of Health Sciences, University of Milan, Italy.
  • Carlo Catani Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo; Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo; Department of Health Sciences, University of Milan, Italy.
  • Luca Malandrino Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo; Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo; Department of Health Sciences, University of Milan, Italy.
  • Elisabetta Candiago Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Giuseppe Ciaravino Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Andrea Gianatti Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Fabiano Di Marco Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, Bergamo; Department of Pathological Anatomy, ASST Papa Giovanni XXIII, Bergamo; Department of Health Sciences, University of Milan, Italy.

A 62-years-old man former occasional smoker was hospitalized for progressive hearing loss and Magnetic Resonance Imaging (MRI) detected multiple round hyperdense lesions in each cerebral hemisphere. Total body Computed Tomography (CT) scan showed a lobulated consolidative lesion on the right lung lower lobe associated to conglomerate lymph nodes (11R) suspected for primary lung cancer. Endoscopy showed an endobronchial invasion and integrated endobronchial ultrasound did not demonstrate any accessible lymph node for sampling. Forceps biopsy report on the endobronchial specimen led to histopathological diagnosis of metastatic melanoma. Skin and ophthalmologic examinations were negative for suspicious pigmented lesions findings and patient had no history of familiarity for melanoma. Malignant melanoma is rarely observed to metastasize to endobronchial tissue and it is represented only in the 4.5% of cases. The vast majority of endobronchial metastases are metachronous, even after several years. Nevertheless, the anachronous manifestations are possible.


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Anelli, M., Raimondi, F., Novelli, L., Allegri, C., Bonetti, S., Catani, C., Malandrino, L., Candiago, E., Ciaravino, G., Gianatti, A., & Di Marco, F. (2024). Hearing loss, why bronchial tree may be involved?. Chest Disease Reports, 12(1). https://doi.org/10.4081/cdr.12.12298

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