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06 | Pharmacological AMPK activation promotes higher levels of Pax7 expression in human muscle stem cells D. Michel1, A. Bouche1|2, R. Mounier3, D. Hannouche1|2, Thomas Laumonier1|2 | 1Cell Therapy and Musculoskeletal Disorders Laboratory, Department of Orthopedic Surgery, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland; 2Department of Cell Physiology and Metabolism, Faculty of Medicine, Geneva, Switzerland; 3Institut Neuromyogène, CNRS 5261 – INSERM U1315 - UCBL1, Lyon, France.
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Abstract 061 | Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance Gaia Gherardi 1, Anna Weiser 2|3, Flavien Bermont 2, Eugenia Migliavacca 2, Benjamin Brinon 2, Guillaume E. Jacot 2, Aurelie Hermant 2, Mattia Sturlese 4, Leonardo Nogara 1|4, Filippo Vascon 5, Agnese De Mario 1, Andrea Mattarei 4, Emma Garratt 6|7, Mark Burton 6, Karen Lillycrop 6|7|8, Keith M. Godfrey 6|7|9, Laura Cendron 5, Denis Barron 2, Stefano Moro 4, Bert Blaauw 1|10, Rosario Rizzuto 1|11, Jerome N. Feige 2|12, Cristina Mammucari 1|11, Umberto De Marchi 2|14 | 1Department of Biomedical Sciences, University of Padova, Padova, Italy; 2Nestlé Institute of Health Sciences, Nestlé Research, Socié té des Produit Nestlé S.A., EPFL Innovation Park, Lausanne, Switzerland; 3Molecular Nutritional Medicine, Else Kroner Fresenius Center for Nutritional Medicine, Technische Universitat Munchen, Freising, Germany; 4Molecular Modeling Section - MMS, Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy; 5Department of Biology, University of Padova, Padova, Italy; 6Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; 7NIHR Southampton Biomedical Research Centre, University of Southampton & University Hospital Southampton NHS Foundation Trust, Southampton, UK; 8Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; 9Medical Research Council Lifecourse Epdemiology Centre, University of Southampton, Southampton, UK; 10Venetian Institute of Molecular Medicine - VIMM, Padova, Italy; 11Myology Center CIR-Myo, University of Padova, Padova, Italy; 12School of Life Sciences, Ecole Polytechnique Federale de Lausanne - EPFL, Lausanne, Switzerland.
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39 | Exploring the role of the chemokine receptor CXCR2 in muscle stem cell heterogeneity Angela Gambardella, G. Andolfi, G. Minchiotti, O. Guardiola | Stem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR, Naples, Italy.
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