Quantitative Computed Tomography and image analysis for advanced muscle assessment

Submitted: 23 May 2016
Accepted: 16 June 2016
Published: 22 June 2016
Abstract Views: 1529
PDF: 734
HTML: 571
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Medical imaging is of particular interest in the field of translational myology, as extant literature describes the utilization of a wide variety of techniques to non-invasively recapitulate and quantity various internal and external tissue morphologies. In the clinical context, medical imaging remains a vital tool for diagnostics and investigative assessment. This review outlines the results from several investigations on the use of computed tomography (CT) and image analysis techniques to assess muscle conditions and degenerative process due to aging or pathological conditions. Herein, we detail the acquisition of spiral CT images and the use of advanced image analysis tools to characterize muscles in 2D and 3D. Results from these studies recapitulate changes in tissue composition within muscles, as visualized by the association of tissue types to specified Hounsfield Unit (HU) values for fat, loose connective tissue or atrophic muscle, and normal muscle, including fascia and tendon. We show how results from these analyses can be presented as both average HU values and compositions with respect to total muscle volumes, demonstrating the reliability of these tools to monitor, assess and characterize muscle degeneration.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

How to Cite

Edmunds, K. J., Gíslason, M. K., Arnadottir, I. D., Marcante, A., Piccione, F., & Gargiulo, P. (2016). Quantitative Computed Tomography and image analysis for advanced muscle assessment. European Journal of Translational Myology, 26(2). https://doi.org/10.4081/ejtm.2016.6015

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.