https://doi.org/10.4081/ejtm.2025.14516
The outcome of severe Guillain-Barré syndrome after robotic or conventional rehabilitation also depends on the triggering agent and the electrophysiological subtype
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Published: 19 December 2025
Dear Editor,
We read with interest the article by Tramonti et al. about a 54-year-old man with severe Guillain-Barré Syndrome (GBS) following a flu-like infection in April 2022, which required long-term intubation and mechanical ventilation.1 Despite immediate treatment with steroids, Intravenous Immunoglobulins (IVIG), and Plasma Exchange (PE), the patient was discharged to a rehabilitation facility after 9 months with severe quadruparesis and weakness of the axial, respiratory, and pharyngeal muscles.1 After intensive rehabilitation with conventional and robot-assisted approaches, the patient's condition improved significantly after another two months.1 The study is noteworthy, but some points require discussion. [...]
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1. Tramonti C, Gnetti B, Gemignani P, et al. Is a multidimensional robotic rehabilitation approach feasible in Guillain-Barrè syndrome? Report from a clinical case. Eur J Transl Myol 2025;35:12758. DOI: https://doi.org/10.4081/ejtm.2025.12758
2. Kilinc D, van de Pasch S, Doets AY, et al. Guillain-Barré syndrome after SARS-CoV-2 infection. Eur J Neurol 2020;27:1757-8. DOI: https://doi.org/10.1111/ene.14398
3. Finsterer J. Triggers of Guillain-Barré Syndrome: Campylobacter jejuni Predominates. Int J Mol Sci 2022;23:14222. DOI: https://doi.org/10.3390/ijms232214222
4. Hughes RA, van Der Meché FG. Corticosteroids for treating Guillain-Barré syndrome. Cochrane Database Syst Rev 2000;3:CD001446. Update in: Cochrane Database Syst Rev 2006;2:CD001446. DOI: https://doi.org/10.1002/14651858.CD001446
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