Deceleration of denervated facial muscle atrophy through functional electrical stimulation: a sonographic quantification in patients with facial nerve paralysis

Submitted: 25 September 2024
Accepted: 3 October 2024
Published: 13 November 2024
Abstract Views: 499
PDF: 167
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Authors

Functional Electrical Stimulation (FES) is an established intervention for a range of muscular and neurological disorders that has already been studied in numerous publications. However, its application to Peripheral Facial nerve Paralysis (PFP) still needs to be sufficiently investigated. As the first approach known to the authors, this study examines the effect of FES on the facial muscles in complete PFP using ultrasonography as a means of observation. In a prospective single-center observational pilot study, ten patients with complete PFP, confirmed by needle-electromyography (EMG), performed FES of the affected lateral mouth region at home twice daily for 20 minutes. The facial muscles’ Cross-Sectional Area (CSA) was regularly assessed using sonographic quantification. While the CSA of most non-stimulated muscles decreased considerably during ongoing paralysis, a significant CSA increase of the Zygomaticus Muscle (ZYG), which was regularly subjected to FES, could be demonstrated. FES can halt the atrophy of denervated ZYG and potentially other facial muscles. Further investigations with a more significant patient collective are recommended. From now on, FES could be established as an additive method in the non-invasive treatment of PFP.

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Citations

Guerreschi P, Labbé D. Sequelae of facial palsy: a comprehensive treatment. Plastic Reconstr Surg 2019;144:682e-92e.
Dobel C, Miltner WHR, Witte OW, et al. Emotionale Auswirkungen einer Fazialisparese. Laryngorhinootologie 2013;92:9-23.
Strobelt L, Kuttenreich A-M, Volk GF, et al. Oral health and oral health-related quality of life in patients with chronic peripheral facial nerve palsy with synkineses—A case-control-study. PLoS One 2022;17:e0276152.
Kurz A, Volk GF, Arnold D, et al. Selective electrical surface stimulation to support functional recovery in the early phase after unilateral acute facial nerve or vocal fold paralysis. Front Neurol 2022;13:869900.
Bersch I, Fridén J. Electrical stimulation alters muscle morphological properties in denervated upper limb muscles. EBioMedicine 2021;74.
Kern H, Salmons S, Mayr W, et al. Recovery of long-term denervated human muscles induced by electrical stimulation. Muscle & Nerve 2005;31:98-101.
Mäkelä E, Venesvirta H, Ilves M, et al. Facial muscle reanimation by transcutaneous electrical stimulation for peripheral facial nerve palsy. J Med Eng Technol 2019;43:155-64.
Bersch I, Mayr W. Electrical stimulation in lower motoneuron lesions, from scientific evidence to clinical practice: a successful transition. Eur J Transl Myol 2023;33:11230.
Arnold D, Thielker J, Klingner CM, et al. Selective Surface Electrostimulation of the Denervated Zygomaticus Muscle. Diagnostics (Basel) 2021;11(2).
Puls WC, Jarvis JC, Ruck A, et al. Surface electrical stimulation for facial paralysis is not harmful. Muscle Nerve 2020;61:347-53.
Volk GF, Sauer M, Pohlmann M, Guntinas-Lichius O. Reference values for dynamic facial muscle ultrasonography in adults. Muscle Nerve 2014;50:348-357.
Guntinas-Lichius O, Volk GF, Olsen KD, et al. Facial nerve electrodiagnostics for patients with facial palsy: a clinical practice guideline. Eur Arch Otorhinolaryngol 2020;277:1855-74.
Geißler K, Guntinas-Lichius O, Fabian Volk G. [Needle electromyography of facial muscles]. Laryngorhinootologie 2016;95:528-9.
Krauß J, Meincke G, Geitner M, et al. Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis: evidence from facial grading and automated image analysis. Eur J Transl Myol 2024, in press.
Sauer M. Instructions for sonography of the facial muscles/Anleitung zur Sonographie der mimischen Muskulatur. Jena, 2013.
Schneider CA, Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 years of image analysis. Nature Methods 2012;9:671-5.
Volk GF, Pohlmann M, Sauer M, et al. Quantitative ultrasonography of facial muscles in patients with chronic facial palsy. Muscle Nerve 2014;50:358-65.
Tuncay F, Borman P, Taşer B, et al. Role of electrical stimulation added to conventional therapy in patients with idiopathic facial (Bell) palsy. Am J Phys Med Rehabil 2015;94:222-8.
Hyvärinen A, Tarkka IM, Mervaala E, et al. Cutaneous electrical stimulation treatment in unresolved facial nerve paralysis: an exploratory study. Am J Phys Med Rehabil 2008;87:992-7.
Doucet BM, Lam A, Griffin L. Neuromuscular electrical stimulation for skeletal muscle function. Yale J Biol Med 2012;85:201-15.
Boncompagni S, Kern H, Rossini K, et al. Structural differentiation of skeletal muscle fibers in the absence of innervation in humans. Proc Natl Acad Sci U S A 2007;104:19339-44.
Radnót M, Follmann P. Ultrastructural changes in senile atrophy of the orbicularis oculi muscle. Am J Ophthalmol 1974;78:689-99.
Mastryukova V, Arnold D, Güllmar D, et al. Can MRI quantify the volume changes of denervated facial muscles? Eur J Transl Myol 2020;30:8918.

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How to Cite

Meincke, G., Krauß, J., Geitner, M., Kuttenreich, A.-M., Arnold, D., Ballmaier, J., Lehmann, T., Mayr, W., Guntinas-Lichius, O., & Volk, G. F. (2024). Deceleration of denervated facial muscle atrophy through functional electrical stimulation: a sonographic quantification in patients with facial nerve paralysis. European Journal of Translational Myology. https://doi.org/10.4081/ejtm.2024.13162

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