Maccarone et al.’s comments on Cohort studies using 3D-CT are needed to assess whether “home Gym-Bed” exercises are beneficial against sarcopenia

We appreciate the insightful comments provided by Josef Finsterer regarding our article on the first evidence on the effects of the Home Full-Body in-Bed Gym protocol as a potential intervention to mitigate age-related muscle loss based on the preliminary positive results of a Padua prospective observational study.¹ We acknowledge the importance of the points raised and would like to address them in this response.

At the University of Padua, we conducted a study aimed at evaluating the impact of a home-based Full-Body in-Bed Gym protocol on various outcomes in elderly individuals, which was published in 2023.¹ The rational of our proposal is based on the fact that functional muscle decay of aging is inevitable, but that the general population is highly hypoactive, let's say "lazy". The increase in daily muscular activity even through “Home In-Bed Gym” recovers at least in part the potential abilities progressively lost. Therefore, it is easy to rejuvenate the “lazy” population, that is, the vast majority of elderlies.[...]