Original Articles

Is a multidimensional robotic rehabilitation approach feasible in Guillain-Barrè syndrome? Report from a clinical case

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Received: 29 November 2024
Accepted: 23 February 2025
Published: 3 July 2025
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We describe the case of a 54-year-old patient, who was admitted to our Rehabilitation Unit with diagnosis of Guillain–Barré Syndrome (GBS). Neurophysiological investigation revealed an axonal polyneuropathy, with impairment of the motor component and preserved sensory function. Despite rapid diagnosis, therapeutic treatment and customized progressive rehabilitation program, nine months after the onset of the disease he presented severe motor sequelae and functional impairment. Patient’s hospitalization lasted about two months, while he performed a conventional rehabilitation training. Besides, he underwent a 4-week comprehensive rehabilitation treatment, including both conventional and robotic multidimensional trainings, for 5 1-h sessions per week. Despite the residual global impairment, this treatment, specifically tailored on patient’s skills and progress, promoted improvements in functional abilities such as motricity, trunk control, and activities of daily living. Therefore, this case report evidenced the feasibility and efficacy of a multidimensional robotic therapeutic approach along with conventional treatment in the post-acute phase of GBS.

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Esposito S, Longo MR, Guillain–Barré syndrome. Autoimmun Rev 2017;16:96-101. DOI: https://doi.org/10.1016/j.autrev.2016.09.022
Shahrizaila N, Lehmann HC, Kuwabara S. Guillain-Barré syndrome. Lancet 2021;397:1214-1228. DOI: https://doi.org/10.1016/S0140-6736(21)00517-1
Hughes RA, Rees JH. Clinical and epidemiologic features of Guillain-Barrè syndrome. Infect Dis 1997;176:92-8. DOI: https://doi.org/10.1086/513793
Mayer JE, McNamara CA, Mayer J. Miller Fisher syndrome and Guillain-Barré syndrome: dual intervention rehabilitation of a complex patient case. Physiother Theory Pract 2022;38:245-54. DOI: https://doi.org/10.1080/09593985.2020.1736221
Restrepo-Jiménez P, Rodríguez Y, González P, et al. The immunotherapy of Guillain-Barré syndrome. Expert Opin Biol Ther 2018;18:619-31. DOI: https://doi.org/10.1080/14712598.2018.1468885
Pritchard J. Novel therapeutic approaches to Guillain-Barré syndrome. Exp Opin Invest Drugs 2000;9:2307-18. DOI: https://doi.org/10.1517/13543784.9.10.2307
Khan F. Rehabilitation in Guillian Barre syndrome. Aust Fam Physician 2004;33:1013-7.
Khan F, Ng L, Amatya B, et al. Multidisciplinary care for Guillain-Barre syndrome. Eur J Phys Rehabil Med 2011;47:607-12. DOI: https://doi.org/10.1002/14651858.CD008505
Jako I, Kollreider A, Germanotta M, et al. Robotic and sensor technology for upper limb rehabilitation. PMR 2018;10:189-97. DOI: https://doi.org/10.1016/j.pmrj.2018.07.011
Medical Research Council of the United Kingdom. Aids to examination of the peripheral nervous system: memorandum no 45. Palo Alto, Calif: Pedragon House; 1978.
Fayazi M, Noorizadeh Dehkordi S, Dadgoo M, et al. Test-retest reliability of Motricity Index strength assessments for lower extremity in post stroke hemiparesis. Med J Islam Repub Iran 2012;26:27–30.
Tramonti C, Graziani F, Pasqualone E, et al. Outpatient rehabilitation in post-acute COVID-19 patients: a combined progressive treatment protocol. Disabil Rehabil 2024;46:5879-89. DOI: https://doi.org/10.1080/09638288.2024.2316797
Franchignoni FP, Tesio L, Ricupero C, et al. Trunk control test as an early predictor of stroke rehabilitation outcome. Stroke 1997;28:1382-5. DOI: https://doi.org/10.1161/01.STR.28.7.1382
Pellicciari L, Basagni B, Paperini A, et al. Trunk control test as a main predictor of the modified barthel index score at discharge from intensive post-acute stroke rehabilitation: results from a multicenter Italian study. Arch Phys Med Rehabil 2024;105:326-34. DOI: https://doi.org/10.1016/j.apmr.2023.08.007
Hsieh YW, Wang CH, Wu SC, et al. Establishing the minimal clinically important difference of the Barthel Index in stroke patients. Neurorehabilit Neural Repair 2007;21:233–8. DOI: https://doi.org/10.1177/1545968306294729
Nguyen DTH, Trinh DTT. Correlation of the Fugl Meyer assessment, Motricity Index and Barthel Index scales in the assessment of rehabilitation in post-stroke patients. Med Pharm Res 2023;7:1-10. DOI: https://doi.org/10.32895/UMP.MPR.7.4.1
Lin C, Arevalo YA, Harvey RL, et al. The minimal clinically important difference of the motricity index score. Top Stroke Rehabil 2023;30:298–303. DOI: https://doi.org/10.1080/10749357.2022.2031532
Ishiwatari M, Honaga K, Tanuma A et al. Trunk impairment as a predictor of activities of daily living in acute stroke. Front Neurol 2021;12:665592. DOI: https://doi.org/10.3389/fneur.2021.665592
Rajabally YA, Uncini A. Outcome and its predictors in Guillaine Barre’ syndrome. J Neurol Neurosurg Psychiatry 2012;83:711-8. DOI: https://doi.org/10.1136/jnnp-2011-301882
Forsberg A, Press R, Einarsson U, et al. Disability and health-related quality of life in Guillain-Barre’ syndrome during the first two years after onset: a prospective study. Clin Rehabil 2005;19:900-9. DOI: https://doi.org/10.1191/0269215505cr918oa
Arsenault NS, Vincent PO, He Shen YB, et al. Influence of exercise on patients with guillain-barre syndrome: a systematic review. Physiotherapy Canada 2016;68:367–76. DOI: https://doi.org/10.3138/ptc.2015-58

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Is a multidimensional robotic rehabilitation approach feasible in Guillain-Barrè syndrome? Report from a clinical case. (2025). European Journal of Translational Myology, 35(3). https://doi.org/10.4081/ejtm.2025.12758