Comparative analysis of MOSESTM technology versus novel thulium fiber laser (TFL) for transurethral enucleation of the prostate: A single-institutional study


Submitted: March 23, 2022
Accepted: April 25, 2022
Published: June 29, 2022
Abstract Views: 1265
PDF: 527
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Authors

  • Hazem Elmansy Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Amr Hodhod Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Ahmed Elshafei Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Yasser A. Noureldin Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada; Urology Department, Benha University, Benha, Egypt.
  • Vahid Mehrnoush Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Ahmed S. Zakaria Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Ruba Abdul Hadi Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Moustafa Fathy Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada; Urology Department, Menoufia University, Shebin Elkom, Egypt.
  • Loay Abbas Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Ahmed Kotb Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
  • Walid Shahrour Urology Department, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.

Introduction: Novel laser technologies have been developed for the minimally invasive surgical management of benign prostatic hyperplasia (BPH). The objective of this study was to assess the safety and efficacy of MOSESTM technology versus the thulium fiber laser (TFL) in patients with BPH undergoing transurethral enucleation of the prostate.
Methods: We conducted a retrospective review of prospectively collected data of eighty-two patients who underwent transurethral enucleation of the prostate using MOSESTM or TFL technologies from August 2020 to September 2021. Preoperative and intraoperative parameters, in addition to postoperative outcomes, were collected and analyzed.
Results: Twenty patients underwent transurethral enucleation of the prostate with TFL, while 62 had MOSESTM HoLEP. No statistically significant difference in preoperative characteristics was observed between the groups. Patients in the TFL group had longer median enucleation, hemostasis, and morcellation times (p < 0.001) than those in the MOSESTM cohort. The longer morcellation time of TFL is mostly related to less visibility. The postoperative outcomes IPSS, QoL, Qmax, and post void residual (PVR), were comparable between the groups at 1, 3 and 6 months. The incidence of urge urinary incontinence (p = 0.79), stress urinary incontinence (p = 0.97), and hospital readmission rates (p = 0.1) were comparable between the two groups.
Conclusions: A satisfactory safety and efficacy profile with comparable postoperative outcomes was demonstrated for both techniques; though, MOSESTM technology was superior to TFL in terms of shorter overall operative time.


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Elmansy, H., Hodhod, A. ., Elshafei, A. ., Noureldin, Y. A. ., Mehrnoush, V. ., Zakaria, A. S. ., Hadi, R. A. ., Fathy, M. ., Abbas, L. ., Kotb, A. ., & Shahrour, W. . (2022). Comparative analysis of MOSES<sup>TM</sup> technology versus novel thulium fiber laser (TFL) for transurethral enucleation of the prostate: A single-institutional study. Archivio Italiano Di Urologia E Andrologia, 94(2), 180–185. https://doi.org/10.4081/aiua.2022.2.180

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