Trends in treatments for erectile dysfunction in Chile between 2010 and 2020 with special focus on penile prostheses
https://doi.org/10.4081/aiua.2022.1.65
Accepted: January 26, 2022
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Objectives: Evidence regarding demand trends for erectile dysfunction (ED) treatments are scarce in South America. This study aims to evaluate trends in ED treatments in Chile over a 10-year period (2010- 2020) and estimate the potential number of candidates for penile prosthesis.
Materials and methods: Sales trends of pharmacological treatments and penile prosthesis were obtained from market studies. The potential number of candidates for penile prosthesis implantation was calculated by crossing epidemiological data with previously reported ED prevalence, proportion of sexually active men, percentage of men seeking medical assistance for ED, and the proportion of patients who are non-responders to ED oral drug therapies
Results: In the 10-year studied period, the Chilean male population older than 50 years increased 34.7%, with an average annual variation (AAV) of 3.4%. For the same period, the sales of oral drug therapies for ED increased by 71.3% (AAV 6.2%), the sales of intracavernosal vasoactive agents (ICVA) decreased by 0.4% (AAV -0.2%), and penile prosthesis sales increased by 113% (AAV 6.7%). We estimated that only 0.05% of sexually active men older than 50 years old with ED who sought medical assistance finally had a penile prosthesis implanted to manage their condition.
Conclusions: Demand for ED oral drug therapies significantly increased in Chile during the last decade, while ICVA remained stable. The annual rate of penile prosthesis implantation increased. However, the gap between the potential penile prosthesis candidates and the actual number of devices implanted is suspected to remain extremely high.
Baas W, O'Connor B, Welliver C, et al. Worldwide trends in penile implantation surgery: data from over 63,000 implants. Transl Androl Urol. 2020; 9:31-37. DOI: https://doi.org/10.21037/tau.2019.09.26
Penile implants or penile prosthesis market - Global industry analysis, size, share, trends and forecast, 2015-2023. https://www.researchandmarkets.com/. ID: 4209017, Report, March 2017.
Lee DJ, Najari BB, Davison W, et al. Trends in the Utilization of Penile Prostheses in the Treatment of Erectile Dysfunction in the United States. J Sex Med. 2015; 12:1638-45. DOI: https://doi.org/10.1111/jsm.12921
Instituto Nacional de Estadística de Chile. www.ine.cl
World Bank national accounts data, and OECD National Accounts data files. GDP per capita (current US$). https://data.worldbank.org/.
World health statistics 2020: monitoring health for the SDGs, sustainable development goals. Geneva: World Health Organization; 2020. www.who.org
Venegas JA, Baeza R. Prevalencia de disfunción eréctil en Chile. Rev Chil Urol. 2004; 69:199-202.
Acuña JI, Marió C, Salazar I, et al. Prevalence of erectile dysfunction in men screened for prostate cancer. Abstracts from the 36th Congress of the Société Internationale d'Urologie, Buenos Aires, Argentina. World J Urol. 2016; 34 (Suppl 1):1-248. DOI: https://doi.org/10.1007/s00345-016-1931-2
Santibañez C, Anchique C, Herdy A, et al. Prevalencia de disfunción eréctil y factores asociados en pacientes con indicación de rehabilitación cardíaca. Rev Chil Cardiol. 2016; 35:216-221. DOI: https://doi.org/10.4067/S0718-85602016000300002
La Sexualidad de lo Chilenos. Encuesta GFK Adimark, año 2017. https://www.gfk.com/es/
Nicolosi A, Buvat J, Glasser DB, et al. Sexual behaviour, sexual dysfunctions and related help seeking patterns in middle-aged and elderly Europeans: the global study of sexual attitudes and behaviors. World J Urol. 2006; 4:423-8. DOI: https://doi.org/10.1007/s00345-006-0088-9
Moreira ED, Glasser DB, Gingell C, et al. Sexual activity, sexual dysfunction and associated help-seeking behaviours in middle-aged and older adults in Spain: a population survey. World J Urol .2005;6:422-9. DOI: https://doi.org/10.1007/s00345-005-0035-1
McMahon C, Smith C, Shabsigh R. Treating erectile dysfunction when PDE5 inhibitors fail. BMJ. 2006; 332:589-92. DOI: https://doi.org/10.1136/bmj.332.7541.589
Goldstein I, Tseng L-J, Creanga D, et al. Efficacy and safety of Sildenafil by age in men with erectile dysfunction. J Sex Med. 2016;13:852-59. DOI: https://doi.org/10.1016/j.jsxm.2016.02.166
Consultora-IQVIA. Informe de evolución del mercado farmacéutico chileno. Santiago, Chile; 2020. www.iqvia.com
Old-age dependency ratio. In Pensions at a glance 2017: OECD and G20 indicators, OECD Publishing, Paris. DOI: https://doi.org/10.1787/pension_glance-2017-22-en DOI: https://doi.org/10.1787/pension_glance-2017-22-en
Deger MD, Madendere S. Erectile dysfunction treatment with Phosphodiesterase-5 Inhibitors: Google trends analysis of last 10 years and COVID-19 pandemic. Arch Ital Urol Androl. 2021;93:361-365. DOI: https://doi.org/10.4081/aiua.2021.3.361
Palmieri A, Silvani M, Giammusso B, et al. A "real life" investigation on the prescriptive habits among Italian andrologists: The "CONSER" survey from Italian Society of Andrology (SIA) on Sildenafil oral film. Arch Ital Urol Androl. 2019; 91:115. DOI: https://doi.org/10.4081/aiua.2019.2.115
Léon P, Seisen T, Mozer P, et al. Trends in the placement of penile prosthesis over the last 17 years in France. Asian J Androl. 2015;17:337-8. DOI: https://doi.org/10.4103/1008-682X.139260
Alwaal A, Al-Sayyad A. Utilization of penile prosthesis and male incontinence prosthetics in Saudi Arabia. J Urol Ann. 2017; 4:353-356. DOI: https://doi.org/10.4103/UA.UA_46_17
Kashanian JA, Golan R, Sun T, et al. Trends in penile prosthetics: influence of patient demographics, surgeon volume, and hospital volume on type of penile prosthesis inserted in New York State. J Sex Med. 2018; 15:245-250. DOI: https://doi.org/10.1016/j.jsxm.2017.12.005
Vakalopoulos I, Kampantais S, Ioannidis S, et al. High patient satisfaction after inflatable penile prosthesis implantation correlates with female partner satisfaction. J Sex Med. 2013; 10:2774-81. DOI: https://doi.org/10.1111/jsm.12311
Pescatori ES, Baldini A, Parazzini F, et al. How much do people know about male sexual problems? A survey in a selected population sample. Arch Ital Urol Androl. 2019; 91:182. DOI: https://doi.org/10.4081/aiua.2019.3.182
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Downloads
Citations
