Original Papers - Stones and Infections

Success rate of Double J stent insertion in patients with advanced cervical cancer and hydronephrosis at tertiary hospital

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: 20 April 2026
Published: 5 June 2026
6
Views
1
Downloads

Authors

Introduction: Obstructive uropathy is a common complication in advanced cervical cancer, occurring because of ureteral compression by the tumour mass and often leading to hydronephrosis and impaired renal function. Double-J (DJ) stent insertion is frequently used as the first-line decompression method to restore ureteral patency; however, its technical success is influenced by anatomical distortion and severity of obstruction. Understanding the factors associated with successful stent placement is essential to guide appropriate urinary diversion strategies.

Materials and methods: This retrospective cross-sectional study included 275 patients with confirmed advanced cervical cancer and hydronephrosis treated at Dr. Saiful Anwar General Hospital, Malang, from January 2019 to July 2025. Data collected included age, cervical cancer stage, hydronephrosis grade, DJ stent insertion status, histopathology findings, and survival status. Statistical analysis using the Kruskal-Wallis test and Spearman correlation assessed the association between clinical variables and DJ stent insertion.

Results: DJ stent insertion was successfully performed in 56.7% of patients. Hydronephrosis grade (p = 0.027) and cervical cancer stage (p = 0.046) were significantly associated with successful stent insertion in univariate analysis, whereas histopathological subtype was not (p = 0.970). Patients with higher-grade hydronephrosis had significantly lower odds of successful stent insertion. Correlation analysis showed no significant monotonic relationship between hydronephrosis severity and cancer stage (ρ = -0.041, p = 0.503). In multivariate logistic regression analysis, severe hydronephrosis emerged as an independent predictor of DJ stent insertion failure (OR 0.30, 95% CI 0.11-0.83, p = 0.021), while cervical cancer stage and histopathological subtype were not significant after adjustment.

Conclusion: Hydronephrosis severity and cervical cancer stage influence the success of DJ stent insertion in advanced cervical cancer; however, hydronephrosis severity appears to be a more direct determinant of stenting feasibility than cancer stage alone, whereas histopathological subtype shows no significant association.

Downloads

Download data is not yet available.

1. Fowler JR, Maani EV, Dunton CJ, et al. Cervical Cancer. 2023 Nov 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026.

2. Shannon M, Grabosch MD. Ovarian cancer staging, TNM and FIGO classifications for ovarian cancer. Medscape; 2021.

3. Perri T, Meller E, Ben-Baruch G, et al. Palliative urinary diversion in patients with malignant ureteric obstruction due to gynaecological cancer. BMJ Support Palliat Care. 2022; 12:e855-e61.

4. Pergialiotis V, Bellos I, Thomakos N, et al. Survival outcomes of patients with cervical cancer and accompanying hydronephrosis: a systematic review of the literature prabhu. Oncol Rev 2019; 13:387.

5. Patel K, Foster NR, Kumar A, et al. Hydronephrosis in patients with cervical cancer: an assessment of morbidity and survival. Support Care Cancer. 2015; 23:1303-9.

6. Dhani FK, Daryanto B, Seputra KP. Survival Outcome of Urinary Diversion in Advanced Cervical Cancer Patients with Hydronephrosis. Asian Pac J Cancer Prev. 2023 Aug 1; 24:2641-2646.

7. Daryanto B, Nurseta T, Wisnu GAMP. Prevalence and survival rate of advanced stage cervical cancer patients with obstructive uropathy in a tertiary hospital. Journal of the Indonesian medical Association. 2024; 74:64-70.

8. Thotakura R, Anjum F. Hydronephrosis and Hydroureter. 2023.

9. Tan ST, Chen X, Sun M, Wu B. The comparation of effects and security of double-J stent retention and ureteroscopy lithotripsy in the treatment of symptomatic ureteral calculi during pregnancy. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018; 227:32-4.

10. Kurata S, Tobu S, Udo K, Noguchi M. Outcomes of Ureteral Stent Placement for Hydronephrosis in Patients with Gynecological Malignancies. Curr Urol. 2017; 10:126-131.

11. Fontham ETH, Wolf AMD, Church TR, et al. Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society. CA Cancer J Clin. 2020; 70:321-346.

12. Noegroho BS, Kurniawan AP, Wijayanti Z, Mustafa A. Factors Affecting Survival Outcome After Percutaneous Nephrostomy as Palliative Urinary Diversion in Obstructive Uropathy due to Advance Cervical Cancer Patients. Asian Pac J Cancer Prev. 2021; 22:1211-1216.

13. Daryanto B, Budaya TN, Purnomo BB. Urine diversion improve survival rate of cervix cancer patients with obstructive uropathy. BJU Int. 2015; 115:33-4.

CRediT authorship contribution

DS: Conceptualization, methodology, investigation, validation, data curation, analysis, visualization, writing – review & editing. BD: Conceptualization, methodology, investigation, analysis, visualization, writing – review & editing, supervision. AFP: Conceptualization, methodology, analysis, writing– review & editing, project administration, supervision

Supporting Agencies

The authors report no funding.

Data Availability Statement

All data underlying the results are available as part of the article and no additional source of data are required.

How to Cite



Success rate of Double J stent insertion in patients with advanced cervical cancer and hydronephrosis at tertiary hospital. (2026). Archivio Italiano Di Urologia E Andrologia. https://doi.org/10.4081/aiua.2026.15582