Letters to the Editor

Treatment with perilesional injections of pentoxifylline in patients with Peyronie's disease improves the therapeutic effect of oral and topical antioxidant therapy

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: 25 December 2024
Published: 11 February 2025
1113
Views
653
Downloads

Authors

To the Editor,

We conducted a retrospective study to demonstrate that it is possible to achieve better therapeutic outcomes through combining perilesional injections of pentoxifylline (PTX) with oral antioxidants and the local application of a cream containing antioxidants and a gel containing diclofenac in patients with Peyronie's disease (PD)...

Downloads

Download data is not yet available.

Pryor JP, Ralph DJ. Clinical presentations of Peyronie’s disease. Int. J Impot Res. 2002; 14:414–417. DOI: https://doi.org/10.1038/sj.ijir.3900877

Garaffa G, Trost LW, Serefoglu EC, et al. Understanding the course of Peyronie's disease. Int J Clin Pract. 2013; 67:781–788. DOI: https://doi.org/10.1111/ijcp.12129

Brant WO, Dean RC, Lue TF. Treatment of Peyronie's disease with oral pentoxifylline. Nat Clin Pract Urol. 2006; 3:111-115. DOI: https://doi.org/10.1038/ncpuro0409

Smith JF, Shindel AW, Huang YC, et al. Pentoxifylline treatment and penile calcifications in men with Peyronie’s disease. Asian J Androl. 2011; 13:322–325. DOI: https://doi.org/10.1038/aja.2010.117

Ibrahim A, Gazzard L, Alharbi M, et al. Evaluation of Oral Pentoxifylline, Colchicine, and Penile Traction for the Management of Peyronie's Disease. Sex Med. 2019; 7:459–463. DOI: https://doi.org/10.1016/j.esxm.2019.07.003

Paulis G, Barletta D, Turchi P, et al. Efficacy and safety evaluation of pentoxifylline associated with other antioxidants in medical treatment of Peyronie’s disease: A case-control study. Res Rep Urol. 2016; 8:1-10. DOI: https://doi.org/10.2147/RRU.S97194

How to Cite



Treatment with perilesional injections of pentoxifylline in patients with Peyronie’s disease improves the therapeutic effect of oral and topical antioxidant therapy. (2025). Archivio Italiano Di Urologia E Andrologia, 97(1). https://doi.org/10.4081/aiua.2025.13525